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Volumn 11, Issue 2, 2016, Pages

Differential roles for DUSP family members in epithelial-to-mesenchymal transition and cancer stem cell regulation in breast cancer

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; CD24 ANTIGEN; DUAL SPECIFICITY PHOSPHATASE; DUAL SPECIFICITY PHOSPHATASE 6; E1A ASSOCIATED P300 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITHELIAL CELL ADHESION MOLECULE; HERMES ANTIGEN; HISTONE H3; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PROTEIN DUSP4; PROTEIN H3K27AC; PROTEIN KINASE C DELTA; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CHROMATIN; EP300 PROTEIN, HUMAN; HISTONE; LYSINE; PROTEIN KINASE C; TUMOR MARKER;

EID: 84959247267     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0148065     Document Type: Article
Times cited : (48)

References (61)
  • 1
    • 84872853140 scopus 로고    scopus 로고
    • Global estimates of cancer prevalence for 27 sites in the adult population in 2008
    • PMID: 22752881
    • Bray F, Ren JS, Masuyer E, Ferlay J (2013) Global estimates of cancer prevalence for 27 sites in the adult population in 2008. Int J Cancer 132: 1133-1145. doi:10.1002/ijc.27711 PMID: 22752881.
    • (2013) Int J Cancer , vol.132 , pp. 1133-1145
    • Bray, F.1    Ren, J.S.2    Masuyer, E.3    Ferlay, J.4
  • 2
    • 84942745805 scopus 로고    scopus 로고
    • New targeted therapies for breast cancer: A focus on tumor microenvironmental signals and chemoresistant breast cancers
    • PMID: 25516852
    • Nwabo Kamdje AH, Seke Etet PF, Vecchio L, Tagne RS, Amvene JM, Muller JM, et al. (2014) New targeted therapies for breast cancer: A focus on tumor microenvironmental signals and chemoresistant breast cancers. World J Clin Cases 2: 769-786. doi:10.12998/wjcc.v2.i12.769 PMID: 25516852.
    • (2014) World J Clin Cases , vol.2 , pp. 769-786
    • Nwabo, K.A.H.1    Seke Etet, P.F.2    Vecchio, L.3    Tagne, R.S.4    Amvene, J.M.5    Muller, J.M.6
  • 3
    • 67650999875 scopus 로고    scopus 로고
    • The basics of epithelial-mesenchymal transition
    • PMID: 19487818
    • Kalluri R, Weinberg RA (2009) The basics of epithelial-mesenchymal transition. J Clin Invest 119: 1420-1428. doi:10.1172/JCI39104 PMID: 19487818.
    • (2009) J Clin Invest , vol.119 , pp. 1420-1428
    • Kalluri, R.1    Weinberg, R.A.2
  • 4
    • 84873050284 scopus 로고    scopus 로고
    • Regulatory networks defining EMT during cancer initiation and progression
    • PMID: 23344542
    • De Craene B, Berx G (2013) Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer 13: 97-110. doi:10.1038/nrc3447 PMID: 23344542.
    • (2013) Nat Rev Cancer , vol.13 , pp. 97-110
    • De Craene, B.1    Berx, G.2
  • 5
    • 84894593599 scopus 로고    scopus 로고
    • Molecular mechanisms of epithelial-mesenchymal transition
    • PMID: 24556840
    • Lamouille S, Xu J, Derynck R (2014) Molecular mechanisms of epithelial-mesenchymal transition. Nature reviews Molecular cell biology 15: 178-196. doi:10.1038/nrm3758 PMID: 24556840.
    • (2014) Nature Reviews Molecular Cell Biology , vol.15 , pp. 178-196
    • Lamouille, S.1    Xu, J.2    Derynck, R.3
  • 6
    • 0031005659 scopus 로고    scopus 로고
    • The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition
    • PMID: 9182671
    • Savagner P, Yamada KM, Thiery JP (1997) The zinc-finger protein slug causes desmosome dissociation, an initial and necessary step for growth factor-induced epithelial-mesenchymal transition. J Cell Biol 137: 1403-1419. PMID: 9182671.
    • (1997) J Cell Biol , vol.137 , pp. 1403-1419
    • Savagner, P.1    Yamada, K.M.2    Thiery, J.P.3
  • 7
    • 0033784843 scopus 로고    scopus 로고
    • The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
    • PMID: 10655586
    • Cano A, Perez-Moreno MA, Rodrigo I, Locascio A, Blanco MJ, del Barrio MG, et al. (2000) The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2: 76-83. PMID: 10655586.
    • (2000) Nat Cell Biol , vol.2 , pp. 76-83
    • Cano, A.1    Perez-Moreno, M.A.2    Rodrigo, I.3    Locascio, A.4    Blanco, M.J.5    Del Barrio, M.G.6
  • 8
    • 84887167622 scopus 로고    scopus 로고
    • Sheep, Wolf, or wereWolf: Cancer stem cells and the epithelial-to-mesenchymal transition
    • PMID: 23499890
    • Chang JT, Mani SA (2013) Sheep, wolf, or werewolf: cancer stem cells and the epithelial-to-mesenchymal transition. Cancer Lett 341: 16-23. doi:10.1016/j.canlet.2013.03.004 PMID: 23499890.
    • (2013) Cancer Lett , vol.341 , pp. 16-23
    • Chang, J.T.1    Mani, S.A.2
  • 9
    • 84896125494 scopus 로고    scopus 로고
    • Evolution of the cancer stem cell model
    • PMID: 24607403
    • Kreso A, Dick JE (2014) Evolution of the cancer stem cell model. Cell Stem Cell 14: 275-291. doi:10.1016/j.stem.2014.02.006 PMID: 24607403.
    • (2014) Cell Stem Cell , vol.14 , pp. 275-291
    • Kreso, A.1    Dick, J.E.2
  • 10
    • 43049165453 scopus 로고    scopus 로고
    • The epithelial-mesenchymal transition generates cells with properties of stem cells
    • PMID: 1848587711
    • Mani SA, Guo W, Liao MJ, Eaton EN, Ayyanan A, Zhou AY, et al. (2008) The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 133: 704-715. doi:10.1016/j.cell.2008.03.027 PMID: 1848587711.
    • (2008) Cell , vol.133 , pp. 704-715
    • Mani, S.A.1    Guo, W.2    Liao, M.J.3    Eaton, E.N.4    Ayyanan, A.5    Zhou, A.Y.6
  • 12
    • 84873811988 scopus 로고    scopus 로고
    • Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
    • PMID: 23372014
    • Yu M, Bardia A, Wittner BS, Stott SL, Smas ME, Ting DT, et al. (2013) Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science 339: 580-584. doi:10.1126/science.1228522PMID: 23372014.
    • (2013) Science , vol.339 , pp. 580-584
    • Yu, M.1    Bardia, A.2    Wittner, B.S.3    Stott, S.L.4    Smas, M.E.5    Ting, D.T.6
  • 13
    • 79955778894 scopus 로고    scopus 로고
    • Breast cancer stem cells: Treatment resistance and therapeutic opportunities
    • PMID: 21310941
    • Al-Ejeh F, Smart CE, Morrison BJ, Chenevix-Trench G, Lopez JA, Lakhani SR, et al. (2011) Breast cancer stem cells: treatment resistance and therapeutic opportunities. Carcinogenesis 32: 650-658. doi:10.1093/carcin/bgr028 PMID: 21310941.
    • (2011) Carcinogenesis , vol.32 , pp. 650-658
    • Al-Ejeh, F.1    Smart, C.E.2    Morrison, B.J.3    Chenevix-Trench, G.4    Lopez, J.A.5    Lakhani, S.R.6
  • 14
    • 0029904681 scopus 로고    scopus 로고
    • Expression of mitogen-activated protein kinase phosphatase-1 in the early phases of human epithelial carcinogenesis
    • PMID: 8909245
    • Loda M, Capodieci P, Mishra R, Yao H, Corless C, Grigioni W, et al. (1996) Expression of mitogen-activated protein kinase phosphatase-1 in the early phases of human epithelial carcinogenesis. Am J Pathol 149: 1553-1564. PMID: 8909245.
    • (1996) Am J Pathol , vol.149 , pp. 1553-1564
    • Loda, M.1    Capodieci, P.2    Mishra, R.3    Yao, H.4    Corless, C.5    Grigioni, W.6
  • 15
    • 66149167313 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase phosphatase-1 in human breast cancer independently predicts prognosis and is repressed by doxorubicin
    • PMID: 19417026
    • Rojo F, Gonzalez-Navarrete I, Bragado R, Dalmases A, Menendez S, Cortes-Sempere M, et al. (2009) Mitogen-activated protein kinase phosphatase-1 in human breast cancer independently predicts prognosis and is repressed by doxorubicin. Clin Cancer Res 15: 3530-3539. doi:10.1158/1078-0432.CCR-08-2070 PMID: 19417026.
    • (2009) Clin Cancer Res , vol.15 , pp. 3530-3539
    • Rojo, F.1    Gonzalez-Navarrete, I.2    Bragado, R.3    Dalmases, A.4    Menendez, S.5    Cortes-Sempere, M.6
  • 16
    • 0037430452 scopus 로고    scopus 로고
    • Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer
    • PMID: 12618338
    • Wang HY, Cheng Z, Malbon CC (2003) Overexpression of mitogen-activated protein kinase phosphatases MKP1, MKP2 in human breast cancer. Cancer Lett 191: 229-237. PMID: 12618338.
    • (2003) Cancer Lett , vol.191 , pp. 229-237
    • Wang, H.Y.1    Cheng, Z.2    Malbon, C.C.3
  • 17
    • 84917677976 scopus 로고    scopus 로고
    • Mitochondrial MKP1 is a target for therapy-resistant HER2-positive breast cancer cells
    • PMID: 25377473
    • Candas D, Lu CL, Fan M, Chuang FY, Sweeney C, Borowsky AD, et al. (2014) Mitochondrial MKP1 is a target for therapy-resistant HER2-positive breast cancer cells. Cancer Res 74: 7498-7509. doi:10.1158/0008-5472.CAN-14-0844 PMID: 25377473.
    • (2014) Cancer Res , vol.74 , pp. 7498-7509
    • Candas, D.1    Lu, C.L.2    Fan, M.3    Chuang, F.Y.4    Sweeney, C.5    Borowsky, A.D.6
  • 18
    • 84921938603 scopus 로고    scopus 로고
    • Dual specificity phosphatase 4 gene expression in association with triple-negative breast cancer outcome
    • PMID: 25281216
    • Baglia ML, Cai Q, Zheng Y, Wu J, Su Y, Ye F, et al. (2014) Dual specificity phosphatase 4 gene expression in association with triple-negative breast cancer outcome. Breast Cancer Res Treat 148: 211- 220. doi:10.1007/s10549-014-3127-z PMID: 25281216.
    • (2014) Breast Cancer Res Treat , vol.148 , pp. 211-220
    • Baglia, M.L.1    Cai, Q.2    Zheng, Y.3    Wu, J.4    Su, Y.5    Ye, F.6
  • 19
    • 3343026531 scopus 로고    scopus 로고
    • Candidate tumor-suppressor genes on chromosome arm 8p in early-onset and high-grade breast cancers
    • PMID: 15184884
    • Armes JE, Hammet F, de Silva M, Ciciulla J, Ramus SJ, Soo WK, et al. (2004) Candidate tumor-suppressor genes on chromosome arm 8p in early-onset and high-grade breast cancers. Oncogene 23: 5697-5702. PMID: 15184884.
    • (2004) Oncogene , vol.23 , pp. 5697-5702
    • Armes, J.E.1    Hammet, F.2    De Silva, M.3    Ciciulla, J.4    Ramus, S.J.5    Soo, W.K.6
  • 20
    • 84925959931 scopus 로고    scopus 로고
    • Clinicopathological significance of dualspecificity protein phosphatase 4 expression in invasive ductal carcinoma of the breast
    • PMID: 25834604
    • Kim H, Jang SM, Ahn H, Sim J, Yi K, Chung Y, et al. (2015) Clinicopathological significance of dualspecificity protein phosphatase 4 expression in invasive ductal carcinoma of the breast. J Breast Cancer 18: 1-7. doi:10.4048/jbc.2015.18.1.1 PMID: 25834604.
    • (2015) J Breast Cancer , vol.18 , pp. 1-7
    • Kim, H.1    Jang, S.M.2    Ahn, H.3    Sim, J.4    Yi, K.5    Chung, Y.6
  • 21
    • 84907684933 scopus 로고    scopus 로고
    • Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor-negative breast cancers
    • PMID: 25201346
    • Manzano RG, Martinez-Navarro EM, Forteza J, Brugarolas A (2014) Microarray phosphatome profiling of breast cancer patients unveils a complex phosphatase regulatory role of the MAPK and PI3K pathways in estrogen receptor-negative breast cancers. Int J Oncol 45: 2250-2266. doi:10.3892/ijo.2014.2648PMID: 25201346.
    • (2014) Int J Oncol , vol.45 , pp. 2250-2266
    • Manzano, R.G.1    Martinez-Navarro, E.M.2    Forteza, J.3    Brugarolas, A.4
  • 22
    • 77953992438 scopus 로고    scopus 로고
    • Expression profile of tyrosine phosphatases in HER2 breast cancer cells and tumors
    • PMID: 20413845
    • Lucci MA, Orlandi R, Triulzi T, Tagliabue E, Balsari A, Villa-Moruzzi E (2010) Expression profile of tyrosine phosphatases in HER2 breast cancer cells and tumors. Cell Oncol 32: 361-372. doi:10.3233/CLO-2010-0520 PMID: 20413845.
    • (2010) Cell Oncol , vol.32 , pp. 361-372
    • Lucci, M.A.1    Orlandi, R.2    Triulzi, T.3    Tagliabue, E.4    Balsari, A.5    Villa-Moruzzi, E.6
  • 23
    • 34249320861 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase phosphatase-1 is a mediator of breast cancer chemoresistance
    • PMID: 17483361
    • Small GW, Shi YY, Higgins LS, Orlowski RZ (2007) Mitogen-activated protein kinase phosphatase-1 is a mediator of breast cancer chemoresistance. Cancer Res 67: 4459-4466. PMID: 17483361.
    • (2007) Cancer Res , vol.67 , pp. 4459-4466
    • Small, G.W.1    Shi, Y.Y.2    Higgins, L.S.3    Orlowski, R.Z.4
  • 25
    • 84887146919 scopus 로고    scopus 로고
    • Knockdown of dual specificity phosphatase 4 enhances the chemosensitivity of MCF-7 and MCF-7/ADR breast cancer cells to doxorubicin
    • PMID: 24012960
    • Liu Y, Du F, Chen W, Yao M, Lv K, Fu P (2013) Knockdown of dual specificity phosphatase 4 enhances the chemosensitivity of MCF-7 and MCF-7/ADR breast cancer cells to doxorubicin. Exp Cell Res 319: 3140-3149. doi:10.1016/j.yexcr.2013.08.023 PMID: 24012960.
    • (2013) Exp Cell Res , vol.319 , pp. 3140-3149
    • Liu, Y.1    Du, F.2    Chen, W.3    Yao, M.4    Lv, K.5    Fu, P.6
  • 26
    • 34250378608 scopus 로고    scopus 로고
    • Expression microarray analysis reveals genes associated with in vitro resistance to cisplatin in a cell line model
    • PMID: 17562441
    • Watson MB, Lind MJ, Smith L, Drew PJ, Cawkwell L (2007) Expression microarray analysis reveals genes associated with in vitro resistance to cisplatin in a cell line model. Acta Oncol 46: 651-658. PMID: 17562441.
    • (2007) Acta Oncol , vol.46 , pp. 651-658
    • Watson, M.B.1    Lind, M.J.2    Smith, L.3    Drew, P.J.4    Cawkwell, L.5
  • 27
    • 33745241078 scopus 로고    scopus 로고
    • Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: A mechanism of tamoxifen resistance
    • PMID: 16740736
    • Cui Y, Parra I, Zhang M, Hilsenbeck SG, Tsimelzon A, Furukawa T, et al. (2006) Elevated expression of mitogen-activated protein kinase phosphatase 3 in breast tumors: A mechanism of tamoxifen resistance. Cancer Res 66: 5950-5959. PMID: 16740736.
    • (2006) Cancer Res , vol.66 , pp. 5950-5959
    • Cui, Y.1    Parra, I.2    Zhang, M.3    Hilsenbeck, S.G.4    Tsimelzon, A.5    Furukawa, T.6
  • 28
    • 84904488713 scopus 로고    scopus 로고
    • Chromatinized PKC-theta directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells
    • Zafar A, Wu F, Hardy K, Li J, Tu WJ, McCuaig R, et al. (2014) Chromatinized PKC-theta directly regulates inducible genes in epithelial to mesenchymal transition and breast cancer stem cells. Mol Cell Biol.
    • (2014) Mol Cell Biol
    • Zafar, A.1    Wu, F.2    Hardy, K.3    Li, J.4    Tu, W.J.5    McCuaig, R.6
  • 29
    • 41749089813 scopus 로고    scopus 로고
    • Replicate-based noise corrected correlation for accurate measurements of colocalization
    • PMID: 18387047
    • Adler J, Pagakis SN, Parmryd I (2008) Replicate-based noise corrected correlation for accurate measurements of colocalization. J Microsc 230: 121-133. doi:10.1111/j.1365-2818.2008.01967.x PMID: 18387047.
    • (2008) J Microsc , vol.230 , pp. 121-133
    • Adler, J.1    Pagakis, S.N.2    Parmryd, I.3
  • 30
    • 84929118611 scopus 로고    scopus 로고
    • The T cell receptor resides in ordered plasma membrane nanodomains that aggregate upon patching of the receptor
    • PMID: 25955440
    • Dinic J, Riehl A, Adler J, Parmryd I (2015) The T cell receptor resides in ordered plasma membrane nanodomains that aggregate upon patching of the receptor. Sci Rep 5: 10082. doi:10.1038/srep10082 PMID: 25955440.
    • (2015) Sci Rep , vol.5 , pp. 10082
    • Dinic, J.1    Riehl, A.2    Adler, J.3    Parmryd, I.4
  • 31
    • 63049103410 scopus 로고    scopus 로고
    • Dynamic histone variant exchange accompanies gene induction in T cells
    • PMID: 19158270
    • Sutcliffe EL, Parish IA, He YQ, Juelich T, Tierney ML, Rangasamy D, et al. (2009) Dynamic histone variant exchange accompanies gene induction in T cells. Mol Cell Biol 29: 1972-1986. doi:10.1128/MCB.01590-08 PMID: 19158270.
    • (2009) Mol Cell Biol , vol.29 , pp. 1972-1986
    • Sutcliffe, E.L.1    Parish, I.A.2    He, Y.Q.3    Juelich, T.4    Tierney, M.L.5    Rangasamy, D.6
  • 32
    • 79952632406 scopus 로고    scopus 로고
    • Chromatin- associated protein kinase C-θ regulates an inducible gene expression program and micrornas in human t lymphocytes
    • PMID: 21419345
    • Sutcliffe Elissa L, Bunting Karen L, He Yi Q, Li J, Phetsouphanh C, Seddiki N, et al. (2011) Chromatin- Associated Protein Kinase C-θ Regulates an Inducible Gene Expression Program and MicroRNAs in Human T Lymphocytes. Molecular Cell 41: 704-719. doi:10.1016/j.molcel.2011.02.030 PMID: 21419345.
    • (2011) Molecular Cell , vol.41 , pp. 704-719
    • Sutcliffe, E.L.1    Bunting, K.L.2    He Yi, Q.3    Li, J.4    Phetsouphanh, C.5    Seddiki, N.6
  • 33
    • 84922938011 scopus 로고    scopus 로고
    • The role of protein kinase-C theta in control of epithelial to mesenchymal transition and cancer stem cell formation
    • PMID: 26484144
    • Zafar A, Hardy K, Wu F, Li J, Rao S (2015) The role of protein kinase-C theta in control of epithelial to mesenchymal transition and cancer stem cell formation. Genomics Data 3: 28-32. doi:10.1016/j.gdata.2014.11.002 PMID: 26484144.
    • (2015) Genomics Data , vol.3 , pp. 28-32
    • Zafar, A.1    Hardy, K.2    Wu, F.3    Li, J.4    Rao, S.5
  • 34
    • 34248210189 scopus 로고    scopus 로고
    • Targeting dual-specificity phosphatases: Manipulating MAP kinase signalling and immune responses
    • PMID: 17473844
    • Jeffrey KL, Camps M, Rommel C, Mackay CR (2007) Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses. Nat Rev Drug Discov 6: 391-403. PMID: 17473844.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 391-403
    • Jeffrey, K.L.1    Camps, M.2    Rommel, C.3    Mackay, C.R.4
  • 35
    • 77953422840 scopus 로고    scopus 로고
    • Phorbol ester phorbol-12- myristate-13-acetate induces epithelial to mesenchymal transition in human prostate cancer ARCaPE cells
    • PMID: 20333698
    • He H, Davidson AJ, Wu D, Marshall FF, Chung LW, Zhau HE, et al. (2010) Phorbol ester phorbol-12- myristate-13-acetate induces epithelial to mesenchymal transition in human prostate cancer ARCaPE cells. Prostate 70: 1119-1126. doi:10.1002/pros.21146 PMID: 20333698.
    • (2010) Prostate , vol.70 , pp. 1119-1126
    • He, H.1    Davidson, A.J.2    Wu, D.3    Marshall, F.F.4    Chung, L.W.5    Zhau, H.E.6
  • 36
    • 1842331095 scopus 로고
    • Phorbol diester receptor copurifies with protein kinase C
    • U S A, PMID: 6296873
    • Niedel JE, Kuhn LJ, Vandenbark GR (1983) Phorbol diester receptor copurifies with protein kinase C. Proc Natl Acad Sci U S A 80: 36-40. PMID: 6296873.
    • (1983) Proc Natl Acad Sci , vol.80 , pp. 36-40
    • Niedel, J.E.1    Kuhn, L.J.2    Vandenbark, G.R.3
  • 37
    • 43049101029 scopus 로고    scopus 로고
    • Dual-specificity MAP kinase phosphatases (MKPs) and cancer
    • PMID: 18330678
    • Keyse SM (2008) Dual-specificity MAP kinase phosphatases (MKPs) and cancer. Cancer Metastasis Rev 27: 253-261. doi:10.1007/s10555-008-9123-1 PMID: 18330678.
    • (2008) Cancer Metastasis Rev , vol.27 , pp. 253-261
    • Keyse, S.M.1
  • 38
    • 33847070442 scopus 로고    scopus 로고
    • The role of chromatin during transcription
    • PMID: 17320508
    • Li B, Carey M, Workman JL (2007) The role of chromatin during transcription. Cell 128: 707-719. PMID: 17320508.
    • (2007) Cell , vol.128 , pp. 707-719
    • Li, B.1    Carey, M.2    Workman, J.L.3
  • 39
    • 34249026300 scopus 로고    scopus 로고
    • High-resolution profiling of histone methylations in the human genome
    • PMID: 17512414
    • Barski A, Cuddapah S, Cui K, Roh TY, Schones DE, Wang Z, et al. (2007) High-resolution profiling of histone methylations in the human genome. Cell 129: 823-837. PMID: 17512414.
    • (2007) Cell , vol.129 , pp. 823-837
    • Barski, A.1    Cuddapah, S.2    Cui, K.3    Roh, T.Y.4    Schones, D.E.5    Wang, Z.6
  • 40
    • 80051564877 scopus 로고    scopus 로고
    • Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions
    • PMID: 21632746
    • Zentner GE, Tesar PJ, Scacheri PC (2011) Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions. Genome Res 21: 1273-1283. doi:10.1101/gr.122382.111 PMID: 21632746.
    • (2011) Genome Res , vol.21 , pp. 1273-1283
    • Zentner, G.E.1    Tesar, P.J.2    Scacheri, P.C.3
  • 41
    • 77953973940 scopus 로고    scopus 로고
    • Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of polycomb group target genes
    • PMID: 20385584
    • Pasini D, Malatesta M, Jung HR, Walfridsson J, Willer A, Olsson L, et al. (2010) Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes. Nucleic Acids Res 38: 4958-4969. doi:10.1093/nar/gkq244PMID: 20385584.
    • (2010) Nucleic Acids Res , vol.38 , pp. 4958-4969
    • Pasini, D.1    Malatesta, M.2    Jung, H.R.3    Walfridsson, J.4    Willer, A.5    Olsson, L.6
  • 42
    • 77957759247 scopus 로고    scopus 로고
    • Activator-dependent p300 acetylation of chromatin in vitro: Enhancement of transcription by disruption of repressive nucleosome- nucleosome interactions
    • PMID: 20720004
    • Szerlong HJ, Prenni JE, Nyborg JK, Hansen JC (2010) Activator-dependent p300 Acetylation of Chromatin in Vitro: ENHANCEMENT OF TRANSCRIPTION BY DISRUPTION OF REPRESSIVE NUCLEOSOME- NUCLEOSOME INTERACTIONS. The Journal of Biological Chemistry 285: 31954-31964. doi:10.1074/jbc.M110.148718 PMID: 20720004.
    • (2010) The Journal of Biological Chemistry , vol.285 , pp. 31954-31964
    • Szerlong, H.J.1    Prenni, J.E.2    Nyborg, J.K.3    Hansen, J.C.4
  • 43
    • 22544466382 scopus 로고    scopus 로고
    • Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity
    • PMID: 16024795
    • Huang WC, Chen CC (2005) Akt phosphorylation of p300 at Ser-1834 is essential for its histone acetyltransferase and transcriptional activity. Mol Cell Biol 25: 6592-6602. PMID: 16024795.
    • (2005) Mol Cell Biol , vol.25 , pp. 6592-6602
    • Huang, W.C.1    Chen, C.C.2
  • 44
    • 0034731524 scopus 로고    scopus 로고
    • Phosphorylation of p300 at serine 89 by protein kinase C
    • PMID: 11020388
    • Yuan LW, Gambee JE (2000) Phosphorylation of p300 at serine 89 by protein kinase C. J Biol Chem 275: 40946-40951. PMID: 11020388.
    • (2000) J Biol Chem , vol.275 , pp. 40946-40951
    • Yuan, L.W.1    Gambee, J.E.2
  • 46
    • 18344375627 scopus 로고    scopus 로고
    • Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors
    • PMID: 11901209
    • Lazo JS, Nemoto K, Pestell KE, Cooley K, Southwick EC, Mitchell DA, et al. (2002) Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors. Mol Pharmacol 61: 720-728. PMID: 11901209.
    • (2002) Mol Pharmacol , vol.61 , pp. 720-728
    • Lazo, J.S.1    Nemoto, K.2    Pestell, K.E.3    Cooley, K.4    Southwick, E.C.5    Mitchell, D.A.6
  • 47
    • 84865750181 scopus 로고    scopus 로고
    • Spinal cannabinoid receptor type 2 agonist reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatases in a rat model of neuropathic pain
    • Landry RP, Martinez E, DeLeo JA, Romero-Sandoval EA (2012) Spinal cannabinoid receptor type 2 agonist reduces mechanical allodynia and induces mitogen-activated protein kinase phosphatases in a rat model of neuropathic pain. The journal of pain: official journal of the American Pain Society 13: 836-848.
    • (2012) The Journal of Pain: Official Journal of the American Pain Society , vol.13 , pp. 836-848
    • Landry, R.P.1    Martinez, E.2    DeLeo, J.A.3    Romero-Sandoval, E.A.4
  • 48
    • 39749109385 scopus 로고    scopus 로고
    • A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone- protected cancer cells
    • PMID: 18245669
    • Vogt A, McDonald PR, Tamewitz A, Sikorski RP, Wipf P, Skoko JJ, et al. (2008) A cell-active inhibitor of mitogen-activated protein kinase phosphatases restores paclitaxel-induced apoptosis in dexamethasone- protected cancer cells. Molecular Cancer Therapeutics 7: 330-340. doi:10.1158/1535-7163.MCT-07-2165PMID: 18245669.
    • (2008) Molecular Cancer Therapeutics , vol.7 , pp. 330-340
    • Vogt, A.1    McDonald, P.R.2    Tamewitz, A.3    Sikorski, R.P.4    Wipf, P.5    Skoko, J.J.6
  • 49
    • 7244254418 scopus 로고    scopus 로고
    • MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2alpha
    • PMID: 15284227
    • Castelli M, Camps M, Gillieron C, Leroy D, Arkinstall S, Rommel C, et al. (2004) MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2alpha. J Biol Chem 279: 44731-44739. PMID: 15284227.
    • (2004) J Biol Chem , vol.279 , pp. 44731-44739
    • Castelli, M.1    Camps, M.2    Gillieron, C.3    Leroy, D.4    Arkinstall, S.5    Rommel, C.6
  • 50
    • 11844294679 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinases phosphorylate mitogen-activated protein kinase phosphatase 3/DUSP6 atSerines 159 and 197, two sites critical for its proteasomal degradation
    • PMID: 15632084
    • Marchetti S, Gimond C, Chambard J-C, Touboul T, Roux D, Pouysségur J, et al. (2005) Extracellular Signal-Regulated Kinases Phosphorylate Mitogen-Activated Protein Kinase Phosphatase 3/DUSP6 atSerines 159 and 197, Two Sites Critical for Its Proteasomal Degradation. Molecular and Cellular Biology 25: 854-864. PMID: 15632084.
    • (2005) Molecular and Cellular Biology , vol.25 , pp. 854-864
    • Marchetti, S.1    Gimond, C.2    Chambard, J.-C.3    Touboul, T.4    Roux, D.5    Pouysségur, J.6
  • 52
    • 84908042343 scopus 로고    scopus 로고
    • Post-translational regulation of mitogen-activated protein kinase phosphatase (MKP)-1 and MKP-2 in macrophages following lipopolysaccharide stimulation: The role of the C termini of the phosphatases in determining their stability
    • PMID: 25204653
    • Crowell S, Wancket LM, Shakibi Y, Xu P, Xue J, Samavati L, et al. (2014) Post-translational regulation of mitogen-activated protein kinase phosphatase (MKP)-1 and MKP-2 in macrophages following lipopolysaccharide stimulation: the role of the C termini of the phosphatases in determining their stability. J Biol Chem 289: 28753-28764. doi:10.1074/jbc.M114.591925 PMID: 25204653.
    • (2014) J Biol Chem , vol.289 , pp. 28753-28764
    • Crowell, S.1    Wancket, L.M.2    Shakibi, Y.3    Xu, P.4    Xue, J.5    Samavati, L.6
  • 53
    • 0033970533 scopus 로고    scopus 로고
    • Dual specificity phosphatases: A gene family for control of MAP kinase function
    • PMID: 10627275
    • Camps M, Nichols A, Arkinstall S (2000) Dual specificity phosphatases: A gene family for control of MAP kinase function. FASEB J 14: 6-16. PMID: 10627275.
    • (2000) FASEB J , vol.14 , pp. 6-16
    • Camps, M.1    Nichols, A.2    Arkinstall, S.3
  • 54
    • 54249119561 scopus 로고    scopus 로고
    • JNK Signaling in Apoptosis
    • PMID: 18931691
    • Dhanasekaran DN, Reddy EP (2008) JNK Signaling in Apoptosis. Oncogene 27: 6245-6251. doi:10.1038/onc.2008.301 PMID: 18931691.
    • (2008) Oncogene , vol.27 , pp. 6245-6251
    • Dhanasekaran, D.N.1    Reddy, E.P.2
  • 55
    • 33748747786 scopus 로고    scopus 로고
    • P38 MAP kinase mediates apoptosis through phosphorylation of bimEL at Ser-65
    • PMID: 16818494
    • Cai B, Chang SH, Becker EBE, Bonni A, Xia Z (2006) p38 MAP Kinase Mediates Apoptosis through Phosphorylation of BimEL at Ser-65. Journal of Biological Chemistry 281: 25215-25222. PMID: 16818494.
    • (2006) Journal of Biological Chemistry , vol.281 , pp. 25215-25222
    • Cai, B.1    Chang, S.H.2    Becker, E.B.E.3    Bonni, A.4    Xia, Z.5
  • 56
    • 0032101707 scopus 로고    scopus 로고
    • Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes
    • PMID: 9606192
    • Werlen G, Jacinto E, Xia Y, Karin M (1998) Calcineurin preferentially synergizes with PKC-theta to activate JNK and IL-2 promoter in T lymphocytes. The EMBO Journal 17: 3101-3111. PMID: 9606192.
    • (1998) The EMBO Journal , vol.17 , pp. 3101-3111
    • Werlen, G.1    Jacinto, E.2    Xia, Y.3    Karin, M.4
  • 57
    • 0031903616 scopus 로고    scopus 로고
    • Co-stimulation-dependent activation of a JNK-kinase in T lymphocytes
    • PMID: 9710210
    • Avraham A, Jung S, Samuels Y, Seger R, Ben-Neriah Y (1998) Co-stimulation-dependent activation of a JNK-kinase in T lymphocytes. Eur J Immunol 28: 2320-2330. PMID: 9710210.
    • (1998) Eur J Immunol , vol.28 , pp. 2320-2330
    • Avraham, A.1    Jung, S.2    Samuels, Y.3    Seger, R.4    Ben-Neriah, Y.5
  • 58
    • 0034288906 scopus 로고    scopus 로고
    • A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation
    • PMID: 10714681
    • Villalba M, Coudronniere N, Deckert M, Teixeiro E, Mas P, Altman A (2000) A novel functional interaction between Vav and PKCtheta is required for TCR-induced T cell activation. Immunity 12: 151-160. PMID: 10714681.
    • (2000) Immunity , vol.12 , pp. 151-160
    • Villalba, M.1    Coudronniere, N.2    Deckert, M.3    Teixeiro, E.4    Mas, P.5    Altman, A.6
  • 59
    • 0033590636 scopus 로고    scopus 로고
    • Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors
    • PMID: 9989833
    • Hoshino R, Chatani Y, Yamori T, Tsuruo T, Oka H, Yoshida O, et al. (1999) Constitutive activation of the 41-/43-kDa mitogen-activated protein kinase signaling pathway in human tumors. Oncogene 18: 813-822. PMID: 9989833.
    • (1999) Oncogene , vol.18 , pp. 813-822
    • Hoshino, R.1    Chatani, Y.2    Yamori, T.3    Tsuruo, T.4    Oka, H.5    Yoshida, O.6
  • 60
    • 0034899045 scopus 로고    scopus 로고
    • Signal pathways which promote invasion and metastasis: Critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways
    • PMID: 11486034
    • Ward Y, Wang W, Woodhouse E, Linnoila I, Liotta L, Kelly K (2001) Signal pathways which promote invasion and metastasis: critical and distinct contributions of extracellular signal-regulated kinase and Ral-specific guanine exchange factor pathways. Mol Cell Biol 21: 5958-5969. PMID: 11486034.
    • (2001) Mol Cell Biol , vol.21 , pp. 5958-5969
    • Ward, Y.1    Wang, W.2    Woodhouse, E.3    Linnoila, I.4    Liotta, L.5    Kelly, K.6
  • 61
    • 6944248910 scopus 로고    scopus 로고
    • Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro
    • PMID: 15548370
    • Xie L, Law BK, Chytil AM, Brown KA, Aakre ME, Moses HL (2004) Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia 6: 603-610. PMID: 15548370.
    • (2004) Neoplasia , vol.6 , pp. 603-610
    • Xie, L.1    Law, B.K.2    Chytil, A.M.3    Brown, K.A.4    Aakre, M.E.5    Moses, H.L.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.