-
1
-
-
2942581416
-
Protein ty-rosine phosphatases in the human genome
-
A. Alonso, J. Sasin, N. Bottini, I. Friedberg, A. Osterman, A. Godzik, T. Hunter, J. Dixon and T. Mustelin, Protein ty-rosine phosphatases in the human genome, Cell 117 (2004), 699-711.
-
(2004)
Cell
, vol.117
, pp. 699-711
-
-
Alonso, A.1
Sasin, J.2
Bottini, N.3
Friedberg, I.4
Osterman, A.5
Godzik, A.6
Hunter, T.7
Dixon, J.8
Mustelin, T.9
-
2
-
-
0347285350
-
A genomic perspective on protein tyrosine phosphatases: Gene structure, pseudogenes and genetic disease linkage
-
J.N. Andersen, P.G. Jansen, S.M. Echwald, O.H. Mortensen, T. Fukada, R. Del Vecchio, N.K. Tonks and N.P. Moller, A genomic perspective on protein tyrosine phosphatases: gene structure, pseudogenes and genetic disease linkage, FA S E B J. 18 (2004), 8-30.
-
(2004)
FA S e B J.
, vol.18
, pp. 8-30
-
-
Andersen, J.N.1
Jansen, P.G.2
Echwald, S.M.3
Mortensen, O.H.4
Fukada, T.5
Del Vecchio, R.6
Tonks, N.K.7
Moller, N.P.8
-
3
-
-
0642337954
-
EGF receptor as a therapeutic target: Patient selection and mechanisms of resistance to receptor-targeted drugs J
-
C.L. Arteaga, EGF receptor as a therapeutic target: patient selection and mechanisms of resistance to receptor-targeted drugs, J. Clin. Oncol. 21 (2003), 289-291.
-
(2003)
Clin. Oncol.
, vol.21
, pp. 289-291
-
-
Arteaga, C.L.1
-
4
-
-
33847375227
-
Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer
-
M. Bentires-Alj and B.G. Neel, Protein-tyrosine phosphatase 1B is required for HER2/Neu-induced breast cancer, Cancer Res. 67 (2007), 2420-2424.
-
(2007)
Cancer Res.
, vol.67
, pp. 2420-2424
-
-
Bentires-Alj, M.1
Neel, B.G.2
-
5
-
-
43049131055
-
Mediators and markers of cancer progression
-
D.C. Bessette, D. Qiu and C.J. Pallen, PRL PTPs: mediators and markers of cancer progression, Cancer Metastasis Rev. 27 (2008), 231-252.
-
(2008)
Cancer Metastasis Rev.
, vol.27
, pp. 231-252
-
-
Bessette, D.C.1
Qiu, D.2
Pallen, C.J.3
Ptps, P.4
-
7
-
-
1642580489
-
Inhibition of proliferation and induction of apoptosis in breast cancer cells by the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ZD1839 ("Iressa") is independent of EGFR expression level
-
M. Campiglio, A. Locatelli, C. Olgiati, N. Normanno, G. Somenzi, L. Vigano, M. Fumagalli, S. Menard and L. Gianni, Inhibition of proliferation and induction of apoptosis in breast cancer cells by the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor ZD1839 ("Iressa") is independent of EGFR expression level, J. Cell. Physiol. 198 (2004), 259-268.
-
(2004)
J. Cell. Physiol.
, vol.198
, pp. 259-268
-
-
Campiglio, M.1
Locatelli, A.2
Olgiati, C.3
Normanno, N.4
Somenzi, G.5
Vigano, L.6
Fumagalli, M.7
Menard, S.8
Gianni, L.9
-
8
-
-
0038612855
-
Role of proliferation in HER2 status predicted response to doxorubicin
-
M. Campiglio, G. Somenzi, C. Olgiati, G. Beretta, A. Balsari, N. Zaffaroni, P. Valagussa and S. Menard, Role of proliferation in HER2 status predicted response to doxorubicin, Int. J. Cancer 105 (2003), 568-573.
-
(2003)
Int. J. Cancer
, vol.105
, pp. 568-573
-
-
Campiglio, M.1
Somenzi, G.2
Olgiati, C.3
Beretta, G.4
Balsari, A.5
Zaffaroni, N.6
Valagussa, P.7
Menard, S.8
-
9
-
-
55549146478
-
Spatiotemporal regulation of ERK2 by dual specificity phosphatases
-
C.J. Caunt, S.P. Armstrong, C.A. Rivers, M.R. Norman and C.A. McArdle, Spatiotemporal regulation of ERK2 by dual specificity phosphatases, J. Biol. Chem. 283 (2008), 26612-26623.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 26612-26623
-
-
Caunt, C.J.1
Armstrong, S.P.2
Rivers, C.A.3
Norman, M.R.4
McArdle, C.A.5
-
10
-
-
1842582811
-
Negative regulation of HER2 signaling by the PEST-type protein-tyrosine phos-phatase BDP1
-
M. Gensler, M. Buschbeck and A. Ullrich, Negative regulation of HER2 signaling by the PEST-type protein-tyrosine phos-phatase BDP1, J. Biol. Chem. 279 (2004), 12110-12116.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 12110-12116
-
-
Gensler, M.1
Buschbeck, M.2
Ullrich, A.3
-
11
-
-
1242316972
-
Protein tyrosine phosphatase ep-silon activates Yes and Fyn in Neu-induced mammary tumor cells
-
S. Granot-Attas and A. Elson, Protein tyrosine phosphatase ep-silon activates Yes and Fyn in Neu-induced mammary tumor cells, Exp. Cell Res. 294 (2004), 236-243.
-
(2004)
Exp. Cell Res.
, vol.294
, pp. 236-243
-
-
Granot-Attas, S.1
Elson, A.2
-
12
-
-
0034638925
-
Molecular mechanisms underlying ErbB2/HER2 action in breast cancer
-
D. Harari and Y. Yarden, Molecular mechanisms underlying ErbB2/HER2 action in breast cancer, Oncogene 19 (2000), 6102-6114.
-
(2000)
Oncogene
, vol.19
, pp. 6102-6114
-
-
Harari, D.1
Yarden, Y.2
-
13
-
-
63749086305
-
ErbB receptors and signaling pathways in cancer
-
N.E. Hynes and G. Macdonald, ErbB receptors and signaling pathways in cancer, Curr. Opin. Cell Biol. 21 (2009), 177-184.
-
(2009)
Curr. Opin. Cell Biol.
, vol.21
, pp. 177-184
-
-
Hynes, N.E.1
MacDonald, G.2
-
14
-
-
43049101029
-
Dual-specificity MAP kinase phosphatases (MKPs) and cancer
-
S.M. Keyse, Dual-specificity MAP kinase phosphatases (MKPs) and cancer, Cancer Metastasis Rev. 27 (2008), 253-261.
-
(2008)
Cancer Metastasis Rev.
, vol.27
, pp. 253-261
-
-
Keyse, S.M.1
-
16
-
-
0033969884
-
Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression
-
S.W. Lee, C.L. Reimer, L. Fang, M.L. Iruela-Arispe and S.A. Aaronson, Overexpression of kinase-associated phosphatase (KAP) in breast and prostate cancer and inhibition of the transformed phenotype by antisense KAP expression, Mol. Cell. Biol. 20 (2000), 1723-1732.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 1723-1732
-
-
Lee, S.W.1
Reimer, C.L.2
Fang, L.3
Iruela-Arispe, M.L.4
Aaronson, S.A.5
-
17
-
-
33751328082
-
ErbB receptors: New insights on mechanisms and biology
-
B. Linggi and G. Carpenter, ErbB receptors: new insights on mechanisms and biology, Trends Cell Biol. 16 (2006), 649-656.
-
(2006)
Trends Cell Biol.
, vol.16
, pp. 649-656
-
-
Linggi, B.1
Carpenter, G.2
-
18
-
-
33746820982
-
Systematic analysis of myotubularins: Heteromeric interactions, subcellular localisation and endosome related functions
-
O. Lorenzo, S. Urbe and M.J. Clague, Systematic analysis of myotubularins: heteromeric interactions, subcellular localisation and endosome related functions, J. Cell Sci. 119 (2006), 2953-2959.
-
(2006)
J. Cell Sci.
, vol.119
, pp. 2953-2959
-
-
Lorenzo, O.1
Urbe, S.2
Clague, M.J.3
-
19
-
-
0242624620
-
Biologic and therapeutic role of HER2 in cancer
-
S. Menard, S.M. Pupa, M. Campiglio and E. Tagliabue, Biologic and therapeutic role of HER2 in cancer, Oncogene 22 (2003), 6570-6578.
-
(2003)
Oncogene
, vol.22
, pp. 6570-6578
-
-
Menard, S.1
Pupa, S.M.2
Campiglio, M.3
Tagliabue, E.4
-
20
-
-
0035476803
-
The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells
-
M.M. Moasser, A. Basso, S.D. Averbuch and N. Rosen, The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells, Cancer Res. 61 (2001), 7184-7188.
-
(2001)
Cancer Res.
, vol.61
, pp. 7184-7188
-
-
Moasser, M.M.1
Basso, A.2
Averbuch, S.D.3
Rosen, N.4
-
21
-
-
33846402073
-
The role of Shp2 (PTPN11) in cancer
-
M.G. Mohi and B.G. Neel, The role of Shp2 (PTPN11) in cancer, Curr. Opin. Genet. Dev. 17 (2007), 23-30.
-
(2007)
Curr. Opin. Genet. Dev.
, vol.17
, pp. 23-30
-
-
Mohi, M.G.1
Neel, B.G.2
-
22
-
-
34547555607
-
Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer
-
B. Naume, X. Zhao, M. Synnestvedt, E. Borgen, H. Gierck-sky Russnes, O.C. Lingjærde, M. Strømberg, G. Wiedswang, G. Kvalheim, R. Kåresen, J.M. Nesland, A.L. Børresen-Dale and T. Sørlie, Presence of bone marrow micrometastasis is associated with different recurrence risk within molecular subtypes of breast cancer, Mol. Oncol. 1 (2007), 160-171.
-
(2007)
Mol. Oncol.
, vol.1
, pp. 160-171
-
-
Naume, B.1
Zhao, X.2
Synnestvedt, M.3
Borgen, E.4
Gierck-Sky Russnes, H.5
Lingjærde, O.C.6
Strømberg, M.7
Wiedswang, G.8
Kvalheim, G.9
Kåresen, R.10
Nesland, J.M.11
Børresen-Dale, A.L.12
Sørlie, T.13
-
23
-
-
0038771965
-
The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
-
B.G. Neel, H. Gu and L. Pao, The 'Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling, Trends Biochem. Sci. 28 (2003), 284-293.
-
(2003)
Trends Biochem. Sci.
, vol.28
, pp. 284-293
-
-
Neel, B.G.1
Gu, H.2
Pao, L.3
-
24
-
-
34248595035
-
Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases
-
D.M. Owens and S.M. Keyse, Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases, Oncogene 26 (2007), 3203-3213.
-
(2007)
Oncogene
, vol.26
, pp. 3203-3213
-
-
Owens, D.M.1
Keyse, S.M.2
-
25
-
-
9244219598
-
Breast cancer-loss of PTEN predicts resistance to treatment
-
P.P. Pandolfi, Breast cancer-loss of PTEN predicts resistance to treatment, N. Engl. J. Med. 351 (2004), 2337-2338.
-
(2004)
N. Engl. J. Med.
, vol.351
, pp. 2337-2338
-
-
Pandolfi, P.P.1
-
26
-
-
33746904684
-
Expression and prognostic impact of the protein ty-rosine phosphatases PRL-1, PRL-2 and PRL-3 in breast cancer
-
I. Radke, M. Gotte, C. Kersting, B. Mattsson, L. Kiesel and P. Wulfing, Expression and prognostic impact of the protein ty-rosine phosphatases PRL-1, PRL-2 and PRL-3 in breast cancer, Br. J. Cancer 95 (2006), 347-354.
-
(2006)
Br J. Cancer
, vol.95
, pp. 347-354
-
-
Radke, I.1
Gotte, M.2
Kersting, C.3
Mattsson, B.4
Kiesel, L.5
Wulfing, P.6
-
27
-
-
33746729798
-
Myotubularin phosphatases: Policing 3-phosphoinositides
-
F.L. Robinson and J.E. Dixon, Myotubularin phosphatases: policing 3-phosphoinositides, Trends Cell Biol. 16 (2006), 403-412.
-
(2006)
Trends Cell Biol.
, vol.16
, pp. 403-412
-
-
Robinson, F.L.1
Dixon, J.E.2
-
28
-
-
17744415869
-
Studies of the HER-2/neu proto-oncogene in human breast cancer
-
D.J. Slamon, Studies of the HER-2/neu proto-oncogene in human breast cancer, Cancer Invest. 8 (1990), 253.
-
(1990)
Cancer Invest.
, vol.8
, pp. 253
-
-
Slamon, D.J.1
-
29
-
-
37049183697
-
Human breast cancer: Correlation of relapse and survival with amplification of the HER-2/neu onco-gene
-
D.J. Slamon, G.M. Clark, S.G. Wong, W.J. Levin, A. Ullrich and W.L. McGuire, Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu onco-gene, Science 235 (1987), 177-182.
-
(1987)
Science
, vol.235
, pp. 177-182
-
-
Slamon, D.J.1
Clark, G.M.2
Wong, S.G.3
Levin, W.J.4
Ullrich, A.5
McGuire, W.L.6
-
30
-
-
0034707581
-
ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases
-
K.S. Spencer, D. Graus-Porta, J. Leng, N.E. Hynes and R.L. Klemke, ErbB2 is necessary for induction of carcinoma cell invasion by ErbB family receptor tyrosine kinases, J. Cell Biol. 148 (2000), 385-397.
-
(2000)
J. Cell Biol.
, vol.148
, pp. 385-397
-
-
Spencer, K.S.1
Graus-Porta, D.2
Leng, J.3
Hynes, N.E.4
Klemke, R.L.5
-
31
-
-
0034007078
-
Nerve growth factor cooperates with p185(HER2) in activating growth of human breast carcinoma cells
-
E. Tagliabue, F. Castiglioni, C. Ghirelli, M. Modugno, L. As-naghi, G. Somenzi, C. Melani and S. Menard, Nerve growth factor cooperates with p185(HER2) in activating growth of human breast carcinoma cells, J. Biol. Chem. 275 (2000), 5388-5394.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 5388-5394
-
-
Tagliabue, E.1
Castiglioni, F.2
Ghirelli, C.3
Modugno, M.4
As-Naghi, L.5
Somenzi, G.6
Melani, C.7
Menard, S.8
-
32
-
-
33750299450
-
Protein tyrosine phosphatases: From genes, to function, to disease
-
N.K. Tonks, Protein tyrosine phosphatases: from genes, to function, to disease, Nat. Rev. Mol. Cell Biol. 7 (2006), 833-846.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 833-846
-
-
Tonks, N.K.1
-
33
-
-
33847391938
-
A brake becomes an accelerator: PTP1B-a new therapeutic target for breast cancer
-
N.K. Tonks and S.K. Muthuswamy, A brake becomes an accelerator: PTP1B-a new therapeutic target for breast cancer, Cancer Cell 11 (2007), 214-216.
-
(2007)
Cancer Cell
, vol.11
, pp. 214-216
-
-
Tonks, N.K.1
Muthuswamy, S.K.2
-
34
-
-
0037137519
-
A gene-expression signature as a predictor of survival in breast cancer
-
DOI 10.1056/NEJMoa021967
-
M.J. van de Vijver, Y.D. He, L.J. van't Veer, H. Dai, A.A. Hart, D.W. Voskuil, G.J. Schreiber, J.L. Peterse, C. Roberts, M.J. Marton, M. Parrish, D. Atsma, A. Witteveen, A. Glas, L. De-lahaye, T. van der Velde, H. Bartelink, S. Rodenhuis, E.T. Rutgers, S.H. Friend and R. Bernards, A gene-expression signature as a predictor of survival in breast cancer, N. Engl. J. Med. 347 (2002), 1999-2009. (Pubitemid 35461656)
-
(2002)
New England Journal of Medicine
, vol.347
, Issue.25
, pp. 1999-2009
-
-
Van De Vijver, M.J.1
He, Y.D.2
Van 'T Veer, L.J.3
Dai, H.4
Hart, A.A.M.5
Voskuil, D.W.6
Schreiber, G.J.7
Peterse, J.L.8
Roberts, C.9
Marton, M.J.10
Parrish, M.11
Atsma, D.12
Witteveen, A.13
Glas, A.14
Delahaye, L.15
Van Der Velde, T.16
Bartelink, H.17
Rodenhuis, S.18
Rutgers, E.T.19
Friend, S.H.20
Bernards, R.21
more..
-
35
-
-
0027504858
-
Activation of the CDC25C phosphatase in mitotic HeLa cells
-
E. Villa-Moruzzi, Activation of the CDC25C phosphatase in mitotic HeLa cells, Biochem. Biophys. Res. Commun. 196 (1993), 1248-1254.
-
(1993)
Biochem. Biophys. Res. Commun.
, vol.196
, pp. 1248-1254
-
-
Villa-Moruzzi, E.1
-
36
-
-
0027240189
-
A protein tyrosine phosphatase activity associated with the hepatocyte growth factor/scatter factor receptor
-
E. Villa-Moruzzi, S. Lapi, M. Prat, G. Gaudino and P.M. Comoglio, A protein tyrosine phosphatase activity associated with the hepatocyte growth factor/scatter factor receptor, J. Biol. Chem. 268 (1993), 18176-18180.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 18176-18180
-
-
Villa-Moruzzi, E.1
Lapi, S.2
Prat, M.3
Gaudino, G.4
Comoglio, P.M.5
-
37
-
-
0032533167
-
Protein tyrosine phosphatase PTP-S binds to the juxtamembrane region of the hepatocyte growth factor receptor met
-
E. Villa-Moruzzi, F. Puntoni, A. Bardelli, E. Vigna, S. De Rosa and P.M. Comoglio, Protein tyrosine phosphatase PTP-S binds to the juxtamembrane region of the hepatocyte growth factor receptor met, Biochem. J. 336 (1998), 235-239.
-
(1998)
Biochem. J.
, vol.336
, pp. 235-239
-
-
Villa-Moruzzi, E.1
Puntoni, F.2
Bardelli, A.3
Vigna, E.4
De Rosa, S.5
Comoglio, P.M.6
-
38
-
-
2442648882
-
Mutational analysis of the tyrosine phosphatome in colorectal cancers
-
Z. Wang, D. Shen, D.W. Parsons, A. Bardelli, J. Sager, S. Szabo, J. Ptak, N. Silliman, B.A. Peters, M.S. van der Hei-jden, G. Parmigiani, H. Yan, T.L. Wang, G. Riggins, S.M. Powell, J.K. Willson, S. Markowitz, K.W. Kinzler, B. Vogel-stein and V.E. Velculescu, Mutational analysis of the tyrosine phosphatome in colorectal cancers, Science 304 (2004), 1164-1166.
-
(2004)
Science
, vol.304
, pp. 1164-1166
-
-
Wang, Z.1
Shen, D.2
Parsons, D.W.3
Bardelli, A.4
Sager, J.5
Szabo, S.6
Ptak, J.7
Silliman, N.8
Peters, B.A.9
Hei-Jden Der Van, M.S.10
Parmigiani, G.11
Yan, H.12
Wang, T.L.13
Riggins, G.14
Powell, S.M.15
Willson, J.K.16
Markowitz, S.17
Kinzler, K.W.18
Vogel-Stein, B.19
Velculescu, V.E.20
more..
-
39
-
-
33750696663
-
Effects of HER2 overexpression on cell signaling networks governing proliferation and migration
-
A. Wolf-Yadlin, N. Kumar, Y. Zhang, S. Hautaniemi, M. Za-man, H.D. Kim, V. Grantcharova, D.A. Lauffenburger and F.M. White, Effects of HER2 overexpression on cell signaling networks governing proliferation and migration, Mol. Syst. Biol. 2 (2006), 54.
-
(2006)
Mol. Syst. Biol.
, vol.2
, pp. 54
-
-
Wolf-Yadlin, A.1
Kumar, N.2
Zhang, Y.3
Hautaniemi, S.4
Za-Man, M.5
Kim, H.D.6
Grantcharova, V.7
Lauffenburger, D.A.8
White, F.M.9
-
41
-
-
58049202164
-
MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia
-
J. Yu, D.G. Ryan, S. Getsios, M. Oliveira-Fernandes, A. Fatima and R.M. Lavker, MicroRNA-184 antagonizes microRNA-205 to maintain SHIP2 levels in epithelia, Proc. Natl. Acad. Sci. USA 105 (2008), 19300-19305.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 19300-19305
-
-
Yu, J.1
Ryan, D.G.2
Getsios, S.3
Oliveira-Fernandes, M.4
Fatima, A.5
Lavker, R.M.6
-
42
-
-
33744912774
-
Controlled activation of ErbB1/ErbB2 heterodimers promote invasion of three-dimensional organized epithelia in an ErbB1-dependent manner: Implications for progression of ErbB2-overexpressing tumors
-
L. Zhan, B. Xiang and S.K. Muthuswamy, Controlled activation of ErbB1/ErbB2 heterodimers promote invasion of three-dimensional organized epithelia in an ErbB1-dependent manner: implications for progression of ErbB2-overexpressing tumors, Cancer Res. 66 (2006), 5201-5208.
-
(2006)
Cancer Res.
, vol.66
, pp. 5201-5208
-
-
Zhan, L.1
Xiang, B.2
Muthuswamy, S.K.3
-
43
-
-
44049108733
-
Inhibition of SHP2 leads to mes-enchymal to epithelial transition in breast cancer cells
-
X.D. Zhou and Y.M. Agazie, Inhibition of SHP2 leads to mes-enchymal to epithelial transition in breast cancer cells, Cell Death Differ. 15 (2008), 988-996.
-
(2008)
Cell Death Differ.
, vol.15
, pp. 988-996
-
-
Zhou, X.D.1
Agazie, Y.M.2
-
44
-
-
42249109536
-
Protein tyrosine phosphatase PTPN13 negatively regulates Her2/ErbB2 malignant signaling
-
J.H. Zhu, R. Chen, W. Yi, G.T. Cantin, C. Fearns, Y. Yang, J.R. Yates 3rd and J.D. Lee, Protein tyrosine phosphatase PTPN13 negatively regulates Her2/ErbB2 malignant signaling, Onco-gene 27 (2008), 2525-2531.
-
(2008)
Onco-gene
, vol.27
, pp. 2525-2531
-
-
Zhu, J.H.1
Chen, R.2
Yi, W.3
Cantin, G.T.4
Fearns, C.5
Yang, Y.6
Iii. Yates, J.R.7
Lee, J.D.8
|