Calcineurin preferentially synergizes with PKC-θ to activate JNK and IL-2 promoter in T lymphocytes

EMBO Journal

Volumn 17, Issue 11, 1998, Pages 3101-3111

  Werlen, Guy ^a   Jacinto, Estela ^a   Xia, Ying ^a   Karin, Michael ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Calcineurin; Interleukin 2; JNK; PKC ; T lymphocyte activation

Indexed keywords

CALCINEURIN; CALCIUM ION; CALCIUM IONOPHORE; CD28 ANTIGEN; CYCLOSPORIN A; INTERLEUKIN 2; ISOENZYME; MITOGEN ACTIVATED PROTEIN KINASE; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; T LYMPHOCYTE RECEPTOR;

ARTICLE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; LEUKEMIA CELL LINE; PRIORITY JOURNAL; PROMOTER REGION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

CALCINEURIN; DRUG SYNERGISM; GENE EXPRESSION REGULATION; GTP PHOSPHOHYDROLASES; GTP-BINDING PROTEINS; HELA CELLS; HUMANS; INTERLEUKIN-2; ISOENZYMES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; JURKAT CELLS; LYMPHOCYTE ACTIVATION; MAP KINASE KINASE 4; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; PROMOTER REGIONS (GENETICS); PROTEIN KINASE C; PROTEIN KINASES; RAC GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 0032101707     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/17.11.3101     Document Type: Article

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