Post-translational regulation of mitogen-activated protein kinase phosphatase (MKP)-1 and MKP-2 in macrophages following lipopolysaccharide stimulation: The role of the ctermini of the phosphatases in determining their stability

Journal of Biological Chemistry

Volumn 289, Issue 42, 2014, Pages 28753-28764

  Crowell, Sara ^a   Wancket, Lyn M ^b   Shakibi, Yasmine ^a   Xu, Pingping ^a   Xue, Jianjing ^a   Samavati, Lobelia ^c   Nelin, Leif D ^a,d   Liu, Yusen ^a,b,d  

^a NATIONWIDE CHILDREN S HOSPITAL   (United States)

^b THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^c OHIO STATE UNIVERSITY   (United States)

^d WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBODIES; CHEMICAL DETECTION; MACROPHAGES; PHOSPHORYLATION;

ENHANCED STABILITY; INNATE IMMUNE RESPONSE; LIPOPOLYSACCHARIDES; MITOGEN ACTIVATED PROTEIN KINASE; PATHWAY INHIBITORS; POLYUBIQUITINATION; POST-TRANSLATIONAL MODIFICATIONS; TRANSLATIONAL REGULATION;

PHOSPHATASES;

ASPARTIC ACID; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1 ANTIBODY; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 2; MONOCLONAL ANTIBODY; PROTEIN ANTIBODY; SERINE; UNCLASSIFIED DRUG; ALANINE; DUAL SPECIFICITY PHOSPHATASE; DUSP1 PROTEIN, HUMAN; DUSP1 PROTEIN, MOUSE; DUSP4 PROTEIN, HUMAN; EPITOPE; MITOGEN ACTIVATED PROTEIN KINASE P38; MKP2 PROTEIN, MOUSE; PROTEASOME INHIBITOR; PROTEIN TYROSINE PHOSPHATASE; UBIQUITIN;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ANTIGEN RECOGNITION; ARTICLE; CONTROLLED STUDY; MACROPHAGE; MOLECULAR WEIGHT; NONHUMAN; PROTEIN DEGRADATION; PROTEIN DEPHOSPHORYLATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN STABILITY; PROTEIN SYNTHESIS; UBIQUITINATION; ANIMAL; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION REGULATION; HEK293 CELL LINE; HUMAN; METABOLISM; MOUSE; PHOSPHORYLATION; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE;

ALANINE; ANIMALS; DUAL SPECIFICITY PHOSPHATASE 1; DUAL-SPECIFICITY PHOSPHATASES; EPITOPES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEK293 CELLS; HUMANS; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE PHOSPHATASES; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTEASOME INHIBITORS; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; PROTEIN TYROSINE PHOSPHATASES; UBIQUITIN;

EID: 84908042343     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.591925     Document Type: Article

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