Dark microglia: A new phenotype predominantly associated with pathological states

GLIA

Volumn 64, Issue 5, 2016, Pages 826-839

  Bisht, Kanchan ^a   Sharma, Kaushik P ^a   Lecours, Cynthia ^a   Gabriela Sánchez, Maria ^a   El Hajj, Hassan ^a   Milior, Giampaolo ^b   Olmos Alonso, Adrián ^c   Gómez Nicola, Diego ^c   Luheshi, Giamal ^d   Vallières, Luc ^a   Branchi, Igor ^e   Maggi, Laura ^b   Limatola, Cristina ^b   Butovsky, Oleg ^f   Tremblay, Marie Ève ^a  

^a LAVAL UNIVERSITY   (Canada)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d DOUGLAS MENTAL HEALTH UNIVERSITY INSTITUTE   (Canada)

^e ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^f BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Aging; Microglia; Neurodegenerative diseases; Stress; Synapses

Indexed keywords

CD11B ANTIGEN; FRACTALKINE; GLIAL FIBRILLARY ACIDIC PROTEIN; IBA1 PROTEIN; PROTEIN; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 2; UNCLASSIFIED DRUG; ALDEHYDE DEHYDROGENASE; ALDH1L1 PROTEIN, HUMAN; AMYLOID PRECURSOR PROTEIN; CHEMOKINE RECEPTOR; CX3CR1 PROTEIN, MOUSE; GREEN FLUORESCENT PROTEIN; LEUKOCYTE ANTIGEN; NERVE PROTEIN; PRESENILIN 1;

AGING; ALZHEIMER DISEASE; AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; CELL MIGRATION; CELL SURVIVAL; CHROMATIN; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHRONIC STRESS; CONTROLLED STUDY; CYTOPLASM; DARK MICROGLIA; DENDRITIC SPINE; ENDOPLASMIC RETICULUM; EXTRACELLULAR SPACE; GENE EXPRESSION; GOLGI COMPLEX; HIPPOCAMPUS; HYPOTHALAMUS; MICROGLIA; MOUSE; NERVE ENDING; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTOSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; STEADY STATE; SYNAPSE; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENETICS; MENTAL STRESS; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

AGING; ALDEHYDE DEHYDROGENASE; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIGENS, CD; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; GREEN FLUORESCENT PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICROGLIA; NERVE TISSUE PROTEINS; PHENOTYPE; PRESENILIN-1; RECEPTORS, CHEMOKINE; STRESS, PSYCHOLOGICAL;

EID: 84958817363     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22966     Document Type: Article

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