Fractalkine receptor deficiency impairs microglial and neuronal responsiveness to chronic stress

Brain, Behavior, and Immunity

Volumn 55, Issue , 2016, Pages 114-125

  Milior, Giampaolo ^a   Lecours, Cynthia ^b   Samson, Louis ^b   Bisht, Kanchan ^b   Poggini, Silvia ^c   Pagani, Francesca ^d   Deflorio, Cristina ^a,e   Lauro, Clotilde ^a   Alboni, Silvia ^f   Limatola, Cristina ^a,g   Branchi, Igor ^c   Tremblay, Marie Eve ^b   Maggi, Laura ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b Université Laval   (Canada)

^c ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^e INSTITUT PASTEUR   (France)

^f UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^g IRCCS NEUROMED   (Italy)

Author keywords

Chronic stress; Differential susceptibility; Environment; Fractalkine receptor; Life events; LTP; Major depression; Microglia; Phagocytosis; Plasticity

Indexed keywords

CHEMOKINE RECEPTOR CX3CR1; CORTICOSTERONE;

ANHEDONIA; ANIMAL CELL; ARTICLE; BRAIN REGION; CELL COMMUNICATION; CELL SIZE; CHRONIC STRESS; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CX3CL1 GENE; ENVIRONMENTAL STRESS; GENE; GENE DELETION; GENOTYPE; HIPPOCAMPAL CA1 REGION; MALE; MICROGLIA; MOUSE; NERVE CELL; NERVE CELL PLASTICITY; NONHUMAN; PHAGOCYTE; PHENOTYPE; PRIORITY JOURNAL; STRATUM RADIATUM; SYNAPSE; SYNAPTIC TRANSMISSION; ANIMAL; ANIMAL BEHAVIOR; C57BL MOUSE; DEFICIENCY; DISEASE MODEL; KNOCKOUT MOUSE; MAJOR DEPRESSION; MENTAL STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; BEHAVIOR, ANIMAL; CX3C CHEMOKINE RECEPTOR 1; DEPRESSIVE DISORDER, MAJOR; DISEASE MODELS, ANIMAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROGLIA; NEURONAL PLASTICITY; NEURONS; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL;

EID: 84938651419     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2015.07.024     Document Type: Article

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