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Volumn 29, Issue 3, 2016, Pages 274-284

Clinical consequences of circulating CD28-negative T cells for solid organ transplantation

Author keywords

CD28; rejection; T cells; tolerance; transplantation

Indexed keywords

ABATACEPT; B7 ANTIGEN; BELATACEPT; CD134 ANTIGEN; CD137 ANTIGEN; CD2 ANTIGEN; CD27 ANTIGEN; CD28 ANTIGEN; CD4 ANTIGEN; CD40 ANTIGEN; CD40 LIGAND; CD57 ANTIGEN; CD86 ANTIGEN; CHEMOKINE RECEPTOR CX3CR1; EFALIZUMAB; INTERLEUKIN 15; INTERLEUKIN 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MYCOPHENOLATE MOFETIL; NATURAL KILLER CELL RECEPTOR; PROGRAMMED DEATH 1 RECEPTOR; STEROID; TRANSCRIPTION FACTOR FOXP3; TUMOR NECROSIS FACTOR ALPHA;

EID: 84958679242     PISSN: 09340874     EISSN: 14322277     Source Type: Journal    
DOI: 10.1111/tri.12658     Document Type: Review
Times cited : (23)

References (120)
  • 1
    • 0027281691 scopus 로고
    • Differential T cell costimulatory requirements in CD28-deficient mice
    • Shahinian A, Pfeffer K, Lee KP, et al,. Differential T cell costimulatory requirements in CD28-deficient mice. Science 1993; 261: 609.
    • (1993) Science , vol.261 , pp. 609
    • Shahinian, A.1    Pfeffer, K.2    Lee, K.P.3
  • 2
    • 0030035269 scopus 로고    scopus 로고
    • Expansion of cytotoxic CD8+ CD28- T cells in healthy ageing people, including centenarians
    • Fagnoni FF, Vescovini R, Mazzola M, et al,. Expansion of cytotoxic CD8+ CD28- T cells in healthy ageing people, including centenarians. Immunology 1996; 88: 501.
    • (1996) Immunology , vol.88 , pp. 501
    • Fagnoni, F.F.1    Vescovini, R.2    Mazzola, M.3
  • 3
    • 0036135578 scopus 로고    scopus 로고
    • Development and homeostasis of T cell memory in rhesus macaque
    • Pitcher CJ, Hagen SI, Walker JM, et al,. Development and homeostasis of T cell memory in rhesus macaque. J Immunol 2002; 168: 29.
    • (2002) J Immunol , vol.168 , pp. 29
    • Pitcher, C.J.1    Hagen, S.I.2    Walker, J.M.3
  • 4
    • 0032478816 scopus 로고    scopus 로고
    • Aging-related deficiency of CD28 expression in CD4+ T cells is associated with the loss of gene-specific nuclear factor binding activity
    • Vallejo AN, Nestel AR, Schirmer M, Weyand CM, Goronzy JJ,. Aging-related deficiency of CD28 expression in CD4+ T cells is associated with the loss of gene-specific nuclear factor binding activity. J Biol Chem 1998; 273: 8119.
    • (1998) J Biol Chem , vol.273 , pp. 8119
    • Vallejo, A.N.1    Nestel, A.R.2    Schirmer, M.3    Weyand, C.M.4    Goronzy, J.J.5
  • 5
    • 33745257254 scopus 로고    scopus 로고
    • A new look at blockade of T-cell costimulation: A therapeutic strategy for long-term maintenance immunosuppression
    • Larsen CP, Knechtle SJ, Adams A, Pearson T, Kirk AD,. A new look at blockade of T-cell costimulation: a therapeutic strategy for long-term maintenance immunosuppression. Am J Transplant 2006; 6: 876.
    • (2006) Am J Transplant , vol.6 , pp. 876
    • Larsen, C.P.1    Knechtle, S.J.2    Adams, A.3    Pearson, T.4    Kirk, A.D.5
  • 6
    • 84927514683 scopus 로고    scopus 로고
    • Regulation of human helper T cell subset differentiation by cytokines
    • Schmitt N, Ueno H,. Regulation of human helper T cell subset differentiation by cytokines. Curr Opin Immunol 2015; 34: 130.
    • (2015) Curr Opin Immunol , vol.34 , pp. 130
    • Schmitt, N.1    Ueno, H.2
  • 7
    • 84876975542 scopus 로고    scopus 로고
    • Immune cell dysfunction and inflammation in end-stage renal disease
    • Betjes MG,. Immune cell dysfunction and inflammation in end-stage renal disease. Nat Rev Nephrol 2013; 9: 255.
    • (2013) Nat Rev Nephrol , vol.9 , pp. 255
    • Betjes, M.G.1
  • 8
    • 35748945719 scopus 로고    scopus 로고
    • The grateful dead: Damage-associated molecular pattern molecules and reduction/oxidation regulate immunity
    • Lotze MT, Zeh HJ, Rubartelli A, et al,. The grateful dead: damage-associated molecular pattern molecules and reduction/oxidation regulate immunity. Immunol Rev 2007; 220: 60.
    • (2007) Immunol Rev , vol.220 , pp. 60
    • Lotze, M.T.1    Zeh, H.J.2    Rubartelli, A.3
  • 9
    • 0347505003 scopus 로고    scopus 로고
    • CD28-mediated co-stimulation: A quantitative support for TCR signalling
    • Acuto O, Michel F,. CD28-mediated co-stimulation: a quantitative support for TCR signalling. Nat Rev Immunol 2003; 3: 939.
    • (2003) Nat Rev Immunol , vol.3 , pp. 939
    • Acuto, O.1    Michel, F.2
  • 10
    • 0037564560 scopus 로고    scopus 로고
    • Molecular modifiers of T cell antigen receptor triggering threshold: The mechanism of CD28 costimulatory receptor
    • Acuto O, Mise-Omata S, Mangino G, Michel F,. Molecular modifiers of T cell antigen receptor triggering threshold: the mechanism of CD28 costimulatory receptor. Immunol Rev 2003; 192: 21.
    • (2003) Immunol Rev , vol.192 , pp. 21
    • Acuto, O.1    Mise-Omata, S.2    Mangino, G.3    Michel, F.4
  • 11
    • 55949116720 scopus 로고    scopus 로고
    • Phenotype and function of human T lymphocyte subsets: Consensus and issues
    • Appay V, van Lier RA, Sallusto F, Roederer M,. Phenotype and function of human T lymphocyte subsets: consensus and issues. Cytometry A 2008; 73: 975.
    • (2008) Cytometry A , vol.73 , pp. 975
    • Appay, V.1    Van Lier, R.A.2    Sallusto, F.3    Roederer, M.4
  • 12
    • 38349171278 scopus 로고    scopus 로고
    • Hepatitis B vaccine-specific CD4(+) T cells can be detected and characterised at the single cell level: Limited usefulness of dendritic cells as signal enhancers
    • Litjens NH, Huisman M, Baan CC, van Druningen CJ, Betjes MG,. Hepatitis B vaccine-specific CD4(+) T cells can be detected and characterised at the single cell level: limited usefulness of dendritic cells as signal enhancers. J Immunol Methods 2008; 330: 1.
    • (2008) J Immunol Methods , vol.330 , pp. 1
    • Litjens, N.H.1    Huisman, M.2    Baan, C.C.3    Van Druningen, C.J.4    Betjes, M.G.5
  • 13
    • 84863720724 scopus 로고    scopus 로고
    • Terminally differentiated CD8+ Temra cells are associated with the risk for acute kidney allograft rejection
    • Betjes MG, Meijers RW, de Wit EA, Weimar W, Litjens NH,. Terminally differentiated CD8+ Temra cells are associated with the risk for acute kidney allograft rejection. Transplantation 2012; 94: 63.
    • (2012) Transplantation , vol.94 , pp. 63
    • Betjes, M.G.1    Meijers, R.W.2    De Wit, E.A.3    Weimar, W.4    Litjens, N.H.5
  • 14
    • 33751169354 scopus 로고    scopus 로고
    • Strong selection of virus-specific cytotoxic CD4+ T-cell clones during primary human cytomegalovirus infection
    • van Leeuwen EM, Remmerswaal EB, Heemskerk MH, ten Berge IJ, van Lier RA,. Strong selection of virus-specific cytotoxic CD4+ T-cell clones during primary human cytomegalovirus infection. Blood 2006; 108: 3121.
    • (2006) Blood , vol.108 , pp. 3121
    • Van Leeuwen, E.M.1    Remmerswaal, E.B.2    Heemskerk, M.H.3    Ten Berge, I.J.4    Van Lier, R.A.5
  • 15
    • 50849124444 scopus 로고    scopus 로고
    • Expansion of cytolytic CD4+CD28- T cells in end-stage renal disease
    • Betjes MG, Huisman M, Weimar W, Litjens NH,. Expansion of cytolytic CD4+CD28- T cells in end-stage renal disease. Kidney Int 2008; 74: 760.
    • (2008) Kidney Int , vol.74 , pp. 760
    • Betjes, M.G.1    Huisman, M.2    Weimar, W.3    Litjens, N.H.4
  • 16
    • 72049120701 scopus 로고    scopus 로고
    • CMV seropositivity determines epoetin dose and hemoglobin levels in patients with CKD
    • Betjes MG, Weimar W, Litjens NH,. CMV seropositivity determines epoetin dose and hemoglobin levels in patients with CKD. J Am Soc Nephrol 2009; 20: 2661.
    • (2009) J Am Soc Nephrol , vol.20 , pp. 2661
    • Betjes, M.G.1    Weimar, W.2    Litjens, N.H.3
  • 17
    • 33751572484 scopus 로고    scopus 로고
    • Generation and growth of CD28nullCD8+ memory T cells mediated by IL-15 and its induced cytokines
    • Chiu WK, Fann M, Weng NP,. Generation and growth of CD28nullCD8+ memory T cells mediated by IL-15 and its induced cytokines. J Immunol 2006; 177: 7802.
    • (2006) J Immunol , vol.177 , pp. 7802
    • Chiu, W.K.1    Fann, M.2    Weng, N.P.3
  • 18
    • 0035951837 scopus 로고    scopus 로고
    • Functional disruption of the CD28 gene transcriptional initiator in senescent T cells
    • Vallejo AN, Weyand CM, Goronzy JJ,. Functional disruption of the CD28 gene transcriptional initiator in senescent T cells. J Biol Chem 2001; 276: 2565.
    • (2001) J Biol Chem , vol.276 , pp. 2565
    • Vallejo, A.N.1    Weyand, C.M.2    Goronzy, J.J.3
  • 20
    • 0033151972 scopus 로고    scopus 로고
    • Modulation of CD28 expression: Distinct regulatory pathways during activation and replicative senescence
    • Vallejo AN, Brandes JC, Weyand CM, Goronzy JJ,. Modulation of CD28 expression: distinct regulatory pathways during activation and replicative senescence. J Immunol 1999; 162: 6572.
    • (1999) J Immunol , vol.162 , pp. 6572
    • Vallejo, A.N.1    Brandes, J.C.2    Weyand, C.M.3    Goronzy, J.J.4
  • 21
    • 0030778838 scopus 로고    scopus 로고
    • Differential down-regulation of CD28 by B7-1 and B7-2 engagement
    • Eck SC, Chang D, Wells AD, Turka LA,. Differential down-regulation of CD28 by B7-1 and B7-2 engagement. Transplantation 1997; 64: 1497.
    • (1997) Transplantation , vol.64 , pp. 1497
    • Eck, S.C.1    Chang, D.2    Wells, A.D.3    Turka, L.A.4
  • 23
    • 3142669281 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription
    • Lewis DE, Merched-Sauvage M, Goronzy JJ, Weyand CM, Vallejo AN,. Tumor necrosis factor-alpha and CD80 modulate CD28 expression through a similar mechanism of T-cell receptor-independent inhibition of transcription. J Biol Chem 2004; 279: 29130.
    • (2004) J Biol Chem , vol.279
    • Lewis, D.E.1    Merched-Sauvage, M.2    Goronzy, J.J.3    Weyand, C.M.4    Vallejo, A.N.5
  • 24
    • 76949101581 scopus 로고    scopus 로고
    • A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study)
    • Vincenti F, Charpentier B, Vanrenterghem Y, et al,. A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT study). Am J Transplant 2010; 10: 535.
    • (2010) Am J Transplant , vol.10 , pp. 535
    • Vincenti, F.1    Charpentier, B.2    Vanrenterghem, Y.3
  • 25
    • 78650925501 scopus 로고    scopus 로고
    • Differential effects of age, cytomegalovirus-seropositivity and end-stage renal disease (ESRD) on circulating T lymphocyte subsets
    • Litjens NH, de Wit EA, Betjes MG,. Differential effects of age, cytomegalovirus-seropositivity and end-stage renal disease (ESRD) on circulating T lymphocyte subsets. Immun Ageing 2011; 8: 2.
    • (2011) Immun Ageing , vol.8 , pp. 2
    • Litjens, N.H.1    De Wit, E.A.2    Betjes, M.G.3
  • 26
    • 84921634186 scopus 로고    scopus 로고
    • Aging of the T cell compartment in mice and humans: From no naive expectations to foggy memories
    • Nikolich-Zugich J,. Aging of the T cell compartment in mice and humans: from no naive expectations to foggy memories. J Immunol 2014; 193: 2622.
    • (2014) J Immunol , vol.193 , pp. 2622
    • Nikolich-Zugich, J.1
  • 27
    • 0035202615 scopus 로고    scopus 로고
    • Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals
    • Goronzy JJ, Fulbright JW, Crowson CS, Poland GA, O'Fallon WM, Weyand CM,. Value of immunological markers in predicting responsiveness to influenza vaccination in elderly individuals. J Virol 2001; 75: 12182.
    • (2001) J Virol , vol.75
    • Goronzy, J.J.1    Fulbright, J.W.2    Crowson, C.S.3    Poland, G.A.4    O'Fallon, W.M.5    Weyand, C.M.6
  • 28
    • 0036604275 scopus 로고    scopus 로고
    • Lack of antibody production following immunization in old age: Association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines
    • Saurwein-Teissl M, Lung TL, Marx F, et al,. Lack of antibody production following immunization in old age: association with CD8(+)CD28(-) T cell clonal expansions and an imbalance in the production of Th1 and Th2 cytokines. J Immunol 2002; 168: 5893.
    • (2002) J Immunol , vol.168 , pp. 5893
    • Saurwein-Teissl, M.1    Lung, T.L.2    Marx, F.3
  • 29
    • 3543069990 scopus 로고    scopus 로고
    • Oligoclonal CD8+ T-cell expansion in patients with chronic hepatitis C is associated with liver pathology and poor response to interferon-alpha therapy
    • Manfras BJ, Weidenbach H, Beckh KH, et al,. Oligoclonal CD8+ T-cell expansion in patients with chronic hepatitis C is associated with liver pathology and poor response to interferon-alpha therapy. J Clin Immunol 2004; 24: 258.
    • (2004) J Clin Immunol , vol.24 , pp. 258
    • Manfras, B.J.1    Weidenbach, H.2    Beckh, K.H.3
  • 30
    • 0036097722 scopus 로고    scopus 로고
    • Peripheral blood and granuloma CD4(+)CD28(-) T cells are a major source of interferon-gamma and tumor necrosis factor-alpha in Wegener's granulomatosis
    • Komocsi A, Lamprecht P, Csernok E, et al,. Peripheral blood and granuloma CD4(+)CD28(-) T cells are a major source of interferon-gamma and tumor necrosis factor-alpha in Wegener's granulomatosis. Am J Pathol 2002; 160: 1717.
    • (2002) Am J Pathol , vol.160 , pp. 1717
    • Komocsi, A.1    Lamprecht, P.2    Csernok, E.3
  • 31
    • 79961208153 scopus 로고    scopus 로고
    • CD8+ CD28- and CD8+ CD57+ T cells and their role in health and disease
    • Strioga M, Pasukoniene V, Characiejus D,. CD8+ CD28- and CD8+ CD57+ T cells and their role in health and disease. Immunology 2011; 134: 17.
    • (2011) Immunology , vol.134 , pp. 17
    • Strioga, M.1    Pasukoniene, V.2    Characiejus, D.3
  • 32
    • 84866050016 scopus 로고    scopus 로고
    • Uremia causes premature ageing of the T cell compartment in end-stage renal disease patients
    • Meijers RW, Litjens NH, de Wit EA, et al,. Uremia causes premature ageing of the T cell compartment in end-stage renal disease patients. Immun Ageing 2012; 9: 19.
    • (2012) Immun Ageing , vol.9 , pp. 19
    • Meijers, R.W.1    Litjens, N.H.2    De Wit, E.A.3
  • 33
    • 84886257843 scopus 로고    scopus 로고
    • Cytomegalovirus contributes partly to uremia-associated premature immunological ageing of the T-cell compartment
    • Meijers RW, Litjens NH, de Wit EA, et al,. Cytomegalovirus contributes partly to uremia-associated premature immunological ageing of the T-cell compartment. Clin Exp Immunol 2013; 174: 424.
    • (2013) Clin Exp Immunol , vol.174 , pp. 424
    • Meijers, R.W.1    Litjens, N.H.2    De Wit, E.A.3
  • 34
    • 29444433970 scopus 로고    scopus 로고
    • Progressive loss of renal function is associated with activation and depletion of naive T lymphocytes
    • Litjens NH, van Druningen CJ, Betjes MG,. Progressive loss of renal function is associated with activation and depletion of naive T lymphocytes. Clin Immunol 2006; 118: 83.
    • (2006) Clin Immunol , vol.118 , pp. 83
    • Litjens, N.H.1    Van Druningen, C.J.2    Betjes, M.G.3
  • 35
    • 36749004391 scopus 로고    scopus 로고
    • Seropositivity for cytomegalovirus in patients with end-stage renal disease is strongly associated with atherosclerotic disease
    • Betjes MG, Litjens NH, Zietse R,. Seropositivity for cytomegalovirus in patients with end-stage renal disease is strongly associated with atherosclerotic disease. Nephrol Dial Transplant 2007; 22: 3298.
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 3298
    • Betjes, M.G.1    Litjens, N.H.2    Zietse, R.3
  • 38
    • 0037561928 scopus 로고    scopus 로고
    • Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells
    • Brenchley JM, Karandikar NJ, Betts MR, et al,. Expression of CD57 defines replicative senescence and antigen-induced apoptotic death of CD8+ T cells. Blood 2003; 101: 2711.
    • (2003) Blood , vol.101 , pp. 2711
    • Brenchley, J.M.1    Karandikar, N.J.2    Betts, M.R.3
  • 39
    • 34548186667 scopus 로고    scopus 로고
    • Cellular senescence: When bad things happen to good cells
    • Campisi J, d'Adda di Fagagna F,. Cellular senescence: when bad things happen to good cells. Nat Rev Mol Cell Biol 2007; 8: 729.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 729
    • Campisi, J.1    D'Adda Di Fagagna, F.2
  • 40
    • 79951912532 scopus 로고    scopus 로고
    • Four faces of cellular senescence
    • Rodier F, Campisi J,. Four faces of cellular senescence. J Cell Biol 2011; 192: 547.
    • (2011) J Cell Biol , vol.192 , pp. 547
    • Rodier, F.1    Campisi, J.2
  • 42
    • 69249238113 scopus 로고    scopus 로고
    • KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells
    • Henson SM, Franzese O, Macaulay R, et al,. KLRG1 signaling induces defective Akt (ser473) phosphorylation and proliferative dysfunction of highly differentiated CD8+ T cells. Blood 2009; 113: 6619.
    • (2009) Blood , vol.113 , pp. 6619
    • Henson, S.M.1    Franzese, O.2    Macaulay, R.3
  • 43
    • 38849191927 scopus 로고    scopus 로고
    • CD8+ CD28- T regulatory lymphocytes inhibiting T cell proliferative and cytotoxic functions infiltrate human cancers
    • Filaci G, Fenoglio D, Fravega M, et al,. CD8+ CD28- T regulatory lymphocytes inhibiting T cell proliferative and cytotoxic functions infiltrate human cancers. J Immunol 2007; 179: 4323.
    • (2007) J Immunol , vol.179 , pp. 4323
    • Filaci, G.1    Fenoglio, D.2    Fravega, M.3
  • 44
    • 84863322171 scopus 로고    scopus 로고
    • A killer on the road: Circulating CD4(+)CD28null T cells as cardiovascular risk factor in ESRD patients
    • Betjes MG, Meijers RW, de Wit LE, Litjens NH,. A killer on the road: circulating CD4(+)CD28null T cells as cardiovascular risk factor in ESRD patients. J Nephrol 2012; 25: 183.
    • (2012) J Nephrol , vol.25 , pp. 183
    • Betjes, M.G.1    Meijers, R.W.2    De Wit, L.E.3    Litjens, N.H.4
  • 45
    • 84925337173 scopus 로고    scopus 로고
    • The story of CD4+ CD28- T cells revisited: Solved or still ongoing?
    • Maly K, Schirmer M,. The story of CD4+ CD28- T cells revisited: solved or still ongoing? J Immunol Res 2015; 2015: 348746.
    • (2015) J Immunol Res , vol.2015
    • Maly, K.1    Schirmer, M.2
  • 46
    • 84927561658 scopus 로고    scopus 로고
    • Characterization and clinical relevance of circulating CD4+CD28- T cells in Graves' disease
    • Wang F, Chen L, Shen Q, et al,. Characterization and clinical relevance of circulating CD4+CD28- T cells in Graves' disease. Immunol Lett 2015; 165: 47.
    • (2015) Immunol Lett , vol.165 , pp. 47
    • Wang, F.1    Chen, L.2    Shen, Q.3
  • 47
    • 84907964868 scopus 로고    scopus 로고
    • CD28(-) CD8(+) T cells are significantly reduced and correlate with disease duration in juveniles with type 1 diabetes
    • Yarde DN, Lorenzo-Arteaga K, Corley KP, Cabrera M, Sarvetnick NE,. CD28(-) CD8(+) T cells are significantly reduced and correlate with disease duration in juveniles with type 1 diabetes. Hum Immunol 2014; 75: 1069.
    • (2014) Hum Immunol , vol.75 , pp. 1069
    • Yarde, D.N.1    Lorenzo-Arteaga, K.2    Corley, K.P.3    Cabrera, M.4    Sarvetnick, N.E.5
  • 48
    • 77950867022 scopus 로고    scopus 로고
    • Numerical defects in CD8+CD28- T-suppressor lymphocyte population in patients with type 1 diabetes mellitus and multiple sclerosis
    • Mikulkova Z, Praksova P, Stourac P, et al,. Numerical defects in CD8+CD28- T-suppressor lymphocyte population in patients with type 1 diabetes mellitus and multiple sclerosis. Cell Immunol 2010; 262: 75.
    • (2010) Cell Immunol , vol.262 , pp. 75
    • Mikulkova, Z.1    Praksova, P.2    Stourac, P.3
  • 49
    • 48249136613 scopus 로고    scopus 로고
    • CD8+CD28-, suppressive T cells in systemic lupus erythematosus
    • Tulunay A, Yavuz S, Direskeneli H, Eksioglu-Demiralp E,. CD8+CD28-, suppressive T cells in systemic lupus erythematosus. Lupus 2008; 17: 630.
    • (2008) Lupus , vol.17 , pp. 630
    • Tulunay, A.1    Yavuz, S.2    Direskeneli, H.3    Eksioglu-Demiralp, E.4
  • 50
    • 84875992640 scopus 로고    scopus 로고
    • Terminally differentiated CD8(+) T cells negatively affect bone regeneration in humans
    • Reinke S, Geissler S, Taylor WR, et al,. Terminally differentiated CD8(+) T cells negatively affect bone regeneration in humans. Sci Transl Med 2013; 5: 177ra36.
    • (2013) Sci Transl Med , vol.5
    • Reinke, S.1    Geissler, S.2    Taylor, W.R.3
  • 51
    • 84895559783 scopus 로고    scopus 로고
    • T cells from chronic bone infection show reduced proliferation and a high proportion of CD28(-) CD4 T cells
    • Kumar G, Roger PM, Ticchioni M, et al,. T cells from chronic bone infection show reduced proliferation and a high proportion of CD28(-) CD4 T cells. Clin Exp Immunol 2014; 176: 49.
    • (2014) Clin Exp Immunol , vol.176 , pp. 49
    • Kumar, G.1    Roger, P.M.2    Ticchioni, M.3
  • 52
    • 3242748853 scopus 로고    scopus 로고
    • Emergence of a CD4+CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection
    • van Leeuwen EM, Remmerswaal EB, Vossen MT, et al,. Emergence of a CD4+CD28- granzyme B+, cytomegalovirus-specific T cell subset after recovery of primary cytomegalovirus infection. J Immunol 2004; 173: 1834.
    • (2004) J Immunol , vol.173 , pp. 1834
    • Van Leeuwen, E.M.1    Remmerswaal, E.B.2    Vossen, M.T.3
  • 54
    • 0038460241 scopus 로고    scopus 로고
    • CD28 loss in senescent CD4+ T cells: Reversal by interleukin-12 stimulation
    • Warrington KJ, Vallejo AN, Weyand CM, Goronzy JJ,. CD28 loss in senescent CD4+ T cells: reversal by interleukin-12 stimulation. Blood 2003; 101: 3543.
    • (2003) Blood , vol.101 , pp. 3543
    • Warrington, K.J.1    Vallejo, A.N.2    Weyand, C.M.3    Goronzy, J.J.4
  • 55
    • 84911370862 scopus 로고    scopus 로고
    • Uremia-associated immunological aging is stably imprinted in the T-cell system and not reversed by kidney transplantation
    • Meijers RW, Litjens NH, de Wit EA, Langerak AW, Baan CC, Betjes MG,. Uremia-associated immunological aging is stably imprinted in the T-cell system and not reversed by kidney transplantation. Transpl Int 2014; 27: 1272.
    • (2014) Transpl Int , vol.27 , pp. 1272
    • Meijers, R.W.1    Litjens, N.H.2    De Wit, E.A.3    Langerak, A.W.4    Baan, C.C.5    Betjes, M.G.6
  • 56
    • 57749208337 scopus 로고    scopus 로고
    • CD4+ CD28 null T cells in coronary artery disease: When helpers become killers
    • Dumitriu IE, Araguas ET, Baboonian C, Kaski JC,. CD4+ CD28 null T cells in coronary artery disease: when helpers become killers. Cardiovasc Res 2009; 81: 11.
    • (2009) Cardiovasc Res , vol.81 , pp. 11
    • Dumitriu, I.E.1    Araguas, E.T.2    Baboonian, C.3    Kaski, J.C.4
  • 58
    • 31344460566 scopus 로고    scopus 로고
    • TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque
    • Sato K, Niessner A, Kopecky SL, Frye RL, Goronzy JJ, Weyand CM,. TRAIL-expressing T cells induce apoptosis of vascular smooth muscle cells in the atherosclerotic plaque. J Exp Med 2006; 203: 239.
    • (2006) J Exp Med , vol.203 , pp. 239
    • Sato, K.1    Niessner, A.2    Kopecky, S.L.3    Frye, R.L.4    Goronzy, J.J.5    Weyand, C.M.6
  • 59
    • 80052811310 scopus 로고    scopus 로고
    • IL-15 preferentially enhances functional properties and antigen-specific responses of CD4+CD28(null) compared to CD4+CD28+ T cells
    • Alonso-Arias R, Moro-Garcia MA, Vidal-Castineira JR, et al,. IL-15 preferentially enhances functional properties and antigen-specific responses of CD4+CD28(null) compared to CD4+CD28+ T cells. Aging Cell 2011; 10: 844.
    • (2011) Aging Cell , vol.10 , pp. 844
    • Alonso-Arias, R.1    Moro-Garcia, M.A.2    Vidal-Castineira, J.R.3
  • 60
    • 84940644780 scopus 로고    scopus 로고
    • CD4+CD28null T lymphocytes resemble CD8+CD28null T lymphocytes in their responses to IL-15 and IL-21 in HIV-infected patients
    • jlb.1A0514-276RR. [Epub ahead of print]
    • Echeverria A, Moro-Garcia MA, Asensi V, Carton JA, Lopez-Larrea C, Alonso-Arias R,. CD4+CD28null T lymphocytes resemble CD8+CD28null T lymphocytes in their responses to IL-15 and IL-21 in HIV-infected patients. J Leukoc Biol 2015; jlb.1A0514-276RR. [Epub ahead of print].
    • (2015) J Leukoc Biol
    • Echeverria, A.1    Moro-Garcia, M.A.2    Asensi, V.3    Carton, J.A.4    Lopez-Larrea, C.5    Alonso-Arias, R.6
  • 61
    • 84901356055 scopus 로고    scopus 로고
    • IL-15 induces alloreactive CD28(-) memory CD8 T cell proliferation and CTLA4-Ig resistant memory CD8 T cell activation
    • Traitanon O, Gorbachev A, Bechtel JJ, et al,. IL-15 induces alloreactive CD28(-) memory CD8 T cell proliferation and CTLA4-Ig resistant memory CD8 T cell activation. Am J Transplant 2014; 14: 1277.
    • (2014) Am J Transplant , vol.14 , pp. 1277
    • Traitanon, O.1    Gorbachev, A.2    Bechtel, J.J.3
  • 62
    • 38849163624 scopus 로고    scopus 로고
    • Sensitive gene expression profiling of human T cell subsets reveals parallel post-thymic differentiation for CD4+ and CD8+ lineages
    • Appay V, Bosio A, Lokan S, et al,. Sensitive gene expression profiling of human T cell subsets reveals parallel post-thymic differentiation for CD4+ and CD8+ lineages. J Immunol 2007; 179: 7406.
    • (2007) J Immunol , vol.179 , pp. 7406
    • Appay, V.1    Bosio, A.2    Lokan, S.3
  • 63
    • 84886264837 scopus 로고    scopus 로고
    • Mesenchymal stem cells control alloreactive CD8(+) CD28(-) T cells
    • Engela AU, Baan CC, Litjens NH, et al,. Mesenchymal stem cells control alloreactive CD8(+) CD28(-) T cells. Clin Exp Immunol 2013; 174: 449.
    • (2013) Clin Exp Immunol , vol.174 , pp. 449
    • Engela, A.U.1    Baan, C.C.2    Litjens, N.H.3
  • 64
    • 78650899002 scopus 로고    scopus 로고
    • Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression
    • Lo DJ, Weaver TA, Stempora L, et al,. Selective targeting of human alloresponsive CD8+ effector memory T cells based on CD2 expression. Am J Transplant 2011; 11: 22.
    • (2011) Am J Transplant , vol.11 , pp. 22
    • Lo, D.J.1    Weaver, T.A.2    Stempora, L.3
  • 66
    • 84883625802 scopus 로고    scopus 로고
    • Activation-induced CD137 is a fast assay for identification and multi-parameter flow-cytometric analysis of alloreactive T cells
    • Litjens NH, de Wit EA, Baan CC, Betjes MG,. Activation-induced CD137 is a fast assay for identification and multi-parameter flow-cytometric analysis of alloreactive T cells. Clin Exp Immunol 2013; 174: 179.
    • (2013) Clin Exp Immunol , vol.174 , pp. 179
    • Litjens, N.H.1    De, W.E.2    Baan, C.C.3    Betjes, M.G.4
  • 68
    • 84860488968 scopus 로고    scopus 로고
    • Prolonged survival of allogeneic islets in cynomolgus monkeys after short-term triple therapy
    • Koulmanda M, Qipo A, Fan Z, et al,. Prolonged survival of allogeneic islets in cynomolgus monkeys after short-term triple therapy. Am J Transplant 2012; 12: 1296.
    • (2012) Am J Transplant , vol.12 , pp. 1296
    • Koulmanda, M.1    Qipo, A.2    Fan, Z.3
  • 69
    • 0035884819 scopus 로고    scopus 로고
    • An antagonist IL-15/Fc protein prevents costimulation blockade-resistant rejection
    • Ferrari-Lacraz S, Zheng XX, Kim YS, et al,. An antagonist IL-15/Fc protein prevents costimulation blockade-resistant rejection. J Immunol 2001; 167: 3478.
    • (2001) J Immunol , vol.167 , pp. 3478
    • Ferrari-Lacraz, S.1    Zheng, X.X.2    Kim, Y.S.3
  • 70
    • 0037103256 scopus 로고    scopus 로고
    • Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals
    • Khan N, Shariff N, Cobbold M, et al,. Cytomegalovirus seropositivity drives the CD8 T cell repertoire toward greater clonality in healthy elderly individuals. J Immunol 2002; 169: 1984.
    • (2002) J Immunol , vol.169 , pp. 1984
    • Khan, N.1    Shariff, N.2    Cobbold, M.3
  • 72
  • 73
    • 79952764290 scopus 로고    scopus 로고
    • Vaccine-induced allo-HLA-reactive memory T cells in a kidney transplantation candidate
    • D'Orsogna LJ, van Besouw NM, van der Meer-Prins EM, et al,. Vaccine-induced allo-HLA-reactive memory T cells in a kidney transplantation candidate. Transplantation 2011; 91: 645.
    • (2011) Transplantation , vol.91 , pp. 645
    • D'Orsogna, L.J.1    Van Besouw, N.M.2    Van Der Meer-Prins, E.M.3
  • 74
    • 41149094672 scopus 로고    scopus 로고
    • Defective alloreactive CD8 T cell function and memory response in allograft recipients in the absence of CD4 help
    • Zhai Y, Wang Y, Wu Z, Kupiec-Weglinski JW,. Defective alloreactive CD8 T cell function and memory response in allograft recipients in the absence of CD4 help. J Immunol 2007; 179: 4529.
    • (2007) J Immunol , vol.179 , pp. 4529
    • Zhai, Y.1    Wang, Y.2    Wu, Z.3    Kupiec-Weglinski, J.W.4
  • 76
    • 47249090442 scopus 로고    scopus 로고
    • A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection
    • Ford ML, Wagener ME, Hanna SS, Pearson TC, Kirk AD, Larsen CP,. A critical precursor frequency of donor-reactive CD4+ T cell help is required for CD8+ T cell-mediated CD28/CD154-independent rejection. J Immunol 2008; 180: 7203.
    • (2008) J Immunol , vol.180 , pp. 7203
    • Ford, M.L.1    Wagener, M.E.2    Hanna, S.S.3    Pearson, T.C.4    Kirk, A.D.5    Larsen, C.P.6
  • 77
    • 48249125001 scopus 로고    scopus 로고
    • CD25, CD28 and CD38 expression in peripheral blood lymphocytes as a tool to predict acute rejection after liver transplantation
    • Boleslawski E, BenOthman S, Grabar S, et al,. CD25, CD28 and CD38 expression in peripheral blood lymphocytes as a tool to predict acute rejection after liver transplantation. Clin Transplant 2008; 22: 494.
    • (2008) Clin Transplant , vol.22 , pp. 494
    • Boleslawski, E.1    BenOthman, S.2    Grabar, S.3
  • 78
    • 67549089794 scopus 로고    scopus 로고
    • Analysis of CD8+CD28- T-suppressor cells in living donor liver transplant recipients
    • Lin YX, Wang LL, Yan LN, et al,. Analysis of CD8+CD28- T-suppressor cells in living donor liver transplant recipients. Hepatobiliary Pancreat Dis Int 2009; 8: 241.
    • (2009) Hepatobiliary Pancreat Dis Int , vol.8 , pp. 241
    • Lin, Y.X.1    Wang, L.L.2    Yan, L.N.3
  • 79
    • 0037239885 scopus 로고    scopus 로고
    • Regulatory CD8+CD28- T cells in heart transplant recipients
    • Colovai AI, Mirza M, Vlad G, et al,. Regulatory CD8+CD28- T cells in heart transplant recipients. Hum Immunol 2003; 64: 31.
    • (2003) Hum Immunol , vol.64 , pp. 31
    • Colovai, A.I.1    Mirza, M.2    Vlad, G.3
  • 80
    • 0034747056 scopus 로고    scopus 로고
    • CD8+CD28- T suppressor cells and the induction of antigen-specific, antigen-presenting cell-mediated suppression of Th reactivity
    • Cortesini R, LeMaoult J, Ciubotariu R, Cortesini NS,. CD8+CD28- T suppressor cells and the induction of antigen-specific, antigen-presenting cell-mediated suppression of Th reactivity. Immunol Rev 2001; 182: 201.
    • (2001) Immunol Rev , vol.182 , pp. 201
    • Cortesini, R.1    LeMaoult, J.2    Ciubotariu, R.3    Cortesini, N.S.4
  • 81
    • 10744227261 scopus 로고    scopus 로고
    • Nonantigen specific CD8+ T suppressor lymphocytes originate from CD8+CD28- T cells and inhibit both T-cell proliferation and CTL function
    • Filaci G, Fravega M, Negrini S, et al,. Nonantigen specific CD8+ T suppressor lymphocytes originate from CD8+CD28- T cells and inhibit both T-cell proliferation and CTL function. Hum Immunol 2004; 65: 142.
    • (2004) Hum Immunol , vol.65 , pp. 142
    • Filaci, G.1    Fravega, M.2    Negrini, S.3
  • 82
    • 85047690427 scopus 로고    scopus 로고
    • Regulatory functions of CD8+CD28- T cells in an autoimmune disease model
    • Najafian N, Chitnis T, Salama AD, et al,. Regulatory functions of CD8+CD28- T cells in an autoimmune disease model. J Clin Invest 2003; 112: 1037.
    • (2003) J Clin Invest , vol.112 , pp. 1037
    • Najafian, N.1    Chitnis, T.2    Salama, A.D.3
  • 84
    • 15444369068 scopus 로고    scopus 로고
    • Reduced immunosuppression in pediatric liver-intestine transplant recipients with CD8+CD28- T-suppressor cells
    • Sindhi R, Manavalan JS, Magill A, Suciu-Foca N, Zeevi A,. Reduced immunosuppression in pediatric liver-intestine transplant recipients with CD8+CD28- T-suppressor cells. Hum Immunol 2005; 66: 252.
    • (2005) Hum Immunol , vol.66 , pp. 252
    • Sindhi, R.1    Manavalan, J.S.2    Magill, A.3    Suciu-Foca, N.4    Zeevi, A.5
  • 85
    • 10344249383 scopus 로고    scopus 로고
    • Molecular characterization of allospecific T suppressor and tolerogenic dendritic cells: Review
    • Suciu-Foca N, Manavalan JS, Scotto L, et al,. Molecular characterization of allospecific T suppressor and tolerogenic dendritic cells: review. Int Immunopharmacol 2005; 5: 7.
    • (2005) Int Immunopharmacol , vol.5 , pp. 7
    • Suciu-Foca, N.1    Manavalan, J.S.2    Scotto, L.3
  • 86
    • 18644366689 scopus 로고    scopus 로고
    • License to heal: Bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC
    • Vlad G, Cortesini R, Suciu-Foca N,. License to heal: bidirectional interaction of antigen-specific regulatory T cells and tolerogenic APC. J Immunol 2005; 174: 5907.
    • (2005) J Immunol , vol.174 , pp. 5907
    • Vlad, G.1    Cortesini, R.2    Suciu-Foca, N.3
  • 87
    • 78651234028 scopus 로고    scopus 로고
    • Gene profile analysis of CD8(+) ILT3-Fc induced T suppressor cells
    • Vlad G, King J, Chang CC, et al,. Gene profile analysis of CD8(+) ILT3-Fc induced T suppressor cells. Hum Immunol 2011; 72: 107.
    • (2011) Hum Immunol , vol.72 , pp. 107
    • Vlad, G.1    King, J.2    Chang, C.C.3
  • 88
    • 63849224217 scopus 로고    scopus 로고
    • Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue
    • Chaput N, Louafi S, Bardier A, et al,. Identification of CD8+CD25+Foxp3+ suppressive T cells in colorectal cancer tissue. Gut 2009; 58: 520.
    • (2009) Gut , vol.58 , pp. 520
    • Chaput, N.1    Louafi, S.2    Bardier, A.3
  • 89
    • 4344675302 scopus 로고    scopus 로고
    • Alloantigen specific CD8+CD28- FOXP3+ T suppressor cells induce ILT3+ ILT4+ tolerogenic endothelial cells, inhibiting alloreactivity
    • Manavalan JS, Kim-Schulze S, Scotto L, et al,. Alloantigen specific CD8+CD28- FOXP3+ T suppressor cells induce ILT3+ ILT4+ tolerogenic endothelial cells, inhibiting alloreactivity. Int Immunol 2004; 16: 1055.
    • (2004) Int Immunol , vol.16 , pp. 1055
    • Manavalan, J.S.1    Kim-Schulze, S.2    Scotto, L.3
  • 90
    • 57649110143 scopus 로고    scopus 로고
    • Advancements on phenotypic and functional characterization of non-antigen-specific CD8+CD28- regulatory T cells
    • Fenoglio D, Ferrera F, Fravega M, et al,. Advancements on phenotypic and functional characterization of non-antigen-specific CD8+CD28- regulatory T cells. Hum Immunol 2008; 69: 745.
    • (2008) Hum Immunol , vol.69 , pp. 745
    • Fenoglio, D.1    Ferrera, F.2    Fravega, M.3
  • 91
    • 32844458509 scopus 로고    scopus 로고
    • Phenotypically and functionally distinct CD8+ lymphocyte populations in long-term drug-free tolerance and chronic rejection in human kidney graft recipients
    • Baeten D, Louis S, Braud C, et al,. Phenotypically and functionally distinct CD8+ lymphocyte populations in long-term drug-free tolerance and chronic rejection in human kidney graft recipients. J Am Soc Nephrol 2006; 17: 294.
    • (2006) J Am Soc Nephrol , vol.17 , pp. 294
    • Baeten, D.1    Louis, S.2    Braud, C.3
  • 92
    • 84921690596 scopus 로고    scopus 로고
    • Expansion of highly differentiated cytotoxic terminally differentiated effector memory CD8+ T cells in a subset of clinically stable kidney transplant recipients: A potential marker for late graft dysfunction
    • Yap M, Boeffard F, Clave E, et al,. Expansion of highly differentiated cytotoxic terminally differentiated effector memory CD8+ T cells in a subset of clinically stable kidney transplant recipients: a potential marker for late graft dysfunction. J Am Soc Nephrol 2014; 25: 1856.
    • (2014) J Am Soc Nephrol , vol.25 , pp. 1856
    • Yap, M.1    Boeffard, F.2    Clave, E.3
  • 93
    • 79952196608 scopus 로고    scopus 로고
    • Circulating pro-inflammatory CD4posCD28null T cells are independently associated with cardiovascular disease in ESRD patients
    • Betjes MG, de Wit EE, Weimar W, Litjens NH,. Circulating pro-inflammatory CD4posCD28null T cells are independently associated with cardiovascular disease in ESRD patients. Nephrol Dial Transplant 2010; 25: 3640.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 3640
    • Betjes, M.G.1    De Wit, E.E.2    Weimar, W.3    Litjens, N.H.4
  • 94
    • 84911423053 scopus 로고    scopus 로고
    • Circulating CD4(+)CD28null T Cells May Increase the Risk of an Atherosclerotic Vascular Event Shortly after Kidney Transplantation
    • Betjes MG, Weimar W, Litjens NH,. Circulating CD4(+)CD28null T Cells May Increase the Risk of an Atherosclerotic Vascular Event Shortly after Kidney Transplantation. J Transplant 2013; 2013: 841430.
    • (2013) J Transplant , vol.2013 , pp. 841430
    • Betjes, M.G.1    Weimar, W.2    Litjens, N.H.3
  • 95
    • 70449730679 scopus 로고    scopus 로고
    • The human alloreactive CD4+ T-cell repertoire is biased to a Th17 response and the frequency is inversely related to the number of HLA class II mismatches
    • Litjens NH, van de Wetering J, van Besouw NM, Betjes MG,. The human alloreactive CD4+ T-cell repertoire is biased to a Th17 response and the frequency is inversely related to the number of HLA class II mismatches. Blood 2009; 114: 3947.
    • (2009) Blood , vol.114 , pp. 3947
    • Litjens, N.H.1    Van De Wetering, J.2    Van Besouw, N.M.3    Betjes, M.G.4
  • 96
    • 33751529566 scopus 로고    scopus 로고
    • Recipient memory-like lymphocytes remain unresponsive to graft antigens after CAMPATH-1H induction with reduced maintenance immunosuppression
    • Trzonkowski P, Zilvetti M, Friend P, Wood KJ,. Recipient memory-like lymphocytes remain unresponsive to graft antigens after CAMPATH-1H induction with reduced maintenance immunosuppression. Transplantation 2006; 82: 1342.
    • (2006) Transplantation , vol.82 , pp. 1342
    • Trzonkowski, P.1    Zilvetti, M.2    Friend, P.3    Wood, K.J.4
  • 97
    • 20044380331 scopus 로고    scopus 로고
    • Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion
    • Pearl JP, Parris J, Hale DA, et al,. Immunocompetent T-cells with a memory-like phenotype are the dominant cell type following antibody-mediated T-cell depletion. Am J Transplant 2005; 5: 465.
    • (2005) Am J Transplant , vol.5 , pp. 465
    • Pearl, J.P.1    Parris, J.2    Hale, D.A.3
  • 98
    • 84955700857 scopus 로고    scopus 로고
    • T-cell ageing in end-stage renal disease patients: Assessment and clinical relevance
    • Meijers RW, Betjes MG, Baan CC, Litjens NH,. T-cell ageing in end-stage renal disease patients: assessment and clinical relevance. World J Nephrol 2014; 3: 268.
    • (2014) World J Nephrol , vol.3 , pp. 268
    • Meijers, R.W.1    Betjes, M.G.2    Baan, C.C.3    Litjens, N.H.4
  • 99
    • 77249175614 scopus 로고    scopus 로고
    • Immunosenescence increases the rate of acceptance of kidney allotransplants in elderly recipients through exhaustion of CD4+ T-cells
    • Trzonkowski P, Debska-Slizien A, Jankowska M, et al,. Immunosenescence increases the rate of acceptance of kidney allotransplants in elderly recipients through exhaustion of CD4+ T-cells. Mech Ageing Dev 2010; 131: 96.
    • (2010) Mech Ageing Dev , vol.131 , pp. 96
    • Trzonkowski, P.1    Debska-Slizien, A.2    Jankowska, M.3
  • 100
    • 84893016687 scopus 로고    scopus 로고
    • Substantial proliferation of human renal tubular epithelial cell-reactive CD4+CD28null memory T cells, which is resistant to tacrolimus and everolimus
    • Demmers MW, Baan CC, Janssen M, et al,. Substantial proliferation of human renal tubular epithelial cell-reactive CD4+CD28null memory T cells, which is resistant to tacrolimus and everolimus. Transplantation 2014; 97: 47.
    • (2014) Transplantation , vol.97 , pp. 47
    • Demmers, M.W.1    Baan, C.C.2    Janssen, M.3
  • 104
    • 84893732562 scopus 로고    scopus 로고
    • 2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses
    • Liu D, Krummey SM, Badell IR, et al,. 2B4 (CD244) induced by selective CD28 blockade functionally regulates allograft-specific CD8+ T cell responses. J Exp Med 2014; 211: 297.
    • (2014) J Exp Med , vol.211 , pp. 297
    • Liu, D.1    Krummey, S.M.2    Badell, I.R.3
  • 105
    • 84874644839 scopus 로고    scopus 로고
    • Costimulation blockade: Current perspectives and implications for therapy
    • Kinnear G, Jones ND, Wood KJ,. Costimulation blockade: current perspectives and implications for therapy. Transplantation 2013; 95: 527.
    • (2013) Transplantation , vol.95 , pp. 527
    • Kinnear, G.1    Jones, N.D.2    Wood, K.J.3
  • 106
    • 84900874350 scopus 로고    scopus 로고
    • Costimulatory pathways in kidney transplantation: Pathogenetic role, clinical significance and new therapeutic opportunities
    • Esposito P, Grosjean F, Rampino T, et al,. Costimulatory pathways in kidney transplantation: pathogenetic role, clinical significance and new therapeutic opportunities. Int Rev Immunol 2014; 33: 212.
    • (2014) Int Rev Immunol , vol.33 , pp. 212
    • Esposito, P.1    Grosjean, F.2    Rampino, T.3
  • 107
    • 84921342432 scopus 로고    scopus 로고
    • New insights into T-cell cosignaling in allograft rejection and survival
    • Krummey SM, Ford ML,. New insights into T-cell cosignaling in allograft rejection and survival. Curr Opin Organ Transplant 2015; 20: 43.
    • (2015) Curr Opin Organ Transplant , vol.20 , pp. 43
    • Krummey, S.M.1    Ford, M.L.2
  • 108
    • 0027419552 scopus 로고
    • Immuno-effector characteristics of peritoneal cells during CAPD treatment: A longitudinal study
    • Betjes MG, Tuk CW, Struijk DG, et al,. Immuno-effector characteristics of peritoneal cells during CAPD treatment: a longitudinal study. Kidney Int 1993; 43: 641.
    • (1993) Kidney Int , vol.43 , pp. 641
    • Betjes, M.G.1    Tuk, C.W.2    Struijk, D.G.3
  • 110
    • 0037108492 scopus 로고    scopus 로고
    • Allograft rejection by primed/memory CD8+ T cells is CD154 blockade resistant: Therapeutic implications for sensitized transplant recipients
    • Zhai Y, Meng L, Gao F, Busuttil RW, Kupiec-Weglinski JW,. Allograft rejection by primed/memory CD8+ T cells is CD154 blockade resistant: therapeutic implications for sensitized transplant recipients. J Immunol 2002; 169: 4667.
    • (2002) J Immunol , vol.169 , pp. 4667
    • Zhai, Y.1    Meng, L.2    Gao, F.3    Busuttil, R.W.4    Kupiec-Weglinski, J.W.5
  • 111
    • 84886917147 scopus 로고    scopus 로고
    • Targeting peripheral blood pro-inflammatory CD28null T cells and natural killer T-like cells by inhibiting CD137 expression: Possible relevance to treatment of bronchiolitis obliterans syndrome
    • Hodge G, Hodge S, Reynolds PN, Holmes M,. Targeting peripheral blood pro-inflammatory CD28null T cells and natural killer T-like cells by inhibiting CD137 expression: possible relevance to treatment of bronchiolitis obliterans syndrome. J Heart Lung Transplant 2013; 32: 1081.
    • (2013) J Heart Lung Transplant , vol.32 , pp. 1081
    • Hodge, G.1    Hodge, S.2    Reynolds, P.N.3    Holmes, M.4
  • 112
    • 80052614854 scopus 로고    scopus 로고
    • Role of increased CD8/CD28(null) T cells and alternative co-stimulatory molecules in chronic obstructive pulmonary disease
    • Hodge G, Mukaro V, Reynolds PN, Hodge S,. Role of increased CD8/CD28(null) T cells and alternative co-stimulatory molecules in chronic obstructive pulmonary disease. Clin Exp Immunol 2011; 166: 94.
    • (2011) Clin Exp Immunol , vol.166 , pp. 94
    • Hodge, G.1    Mukaro, V.2    Reynolds, P.N.3    Hodge, S.4
  • 113
    • 84858634013 scopus 로고    scopus 로고
    • High levels of costimulatory receptors OX40 and 4-1BB characterize CD4+CD28null T cells in patients with acute coronary syndrome
    • Dumitriu IE, Baruah P, Finlayson CJ, et al,. High levels of costimulatory receptors OX40 and 4-1BB characterize CD4+CD28null T cells in patients with acute coronary syndrome. Circ Res 2012; 110: 857.
    • (2012) Circ Res , vol.110 , pp. 857
    • Dumitriu, I.E.1    Baruah, P.2    Finlayson, C.J.3
  • 115
    • 84888386923 scopus 로고    scopus 로고
    • Alefacept promotes immunosuppression-free renal allograft survival in nonhuman primates via depletion of recipient memory T cells
    • Lee S, Yamada Y, Tonsho M, et al,. Alefacept promotes immunosuppression-free renal allograft survival in nonhuman primates via depletion of recipient memory T cells. Am J Transplant 2013; 13: 3223.
    • (2013) Am J Transplant , vol.13 , pp. 3223
    • Lee, S.1    Yamada, Y.2    Tonsho, M.3
  • 116
    • 84865576661 scopus 로고    scopus 로고
    • Enhanced de novo alloantibody and antibody-mediated injury in rhesus macaques
    • Page EK, Page AJ, Kwun J, et al,. Enhanced de novo alloantibody and antibody-mediated injury in rhesus macaques. Am J Transplant 2012; 12: 2395.
    • (2012) Am J Transplant , vol.12 , pp. 2395
    • Page, E.K.1    Page, A.J.2    Kwun, J.3
  • 117
    • 67650506103 scopus 로고    scopus 로고
    • Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates
    • Weaver TA, Charafeddine AH, Agarwal A, et al,. Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates. Nat Med 2009; 15: 746.
    • (2009) Nat Med , vol.15 , pp. 746
    • Weaver, T.A.1    Charafeddine, A.H.2    Agarwal, A.3
  • 118
    • 84873092678 scopus 로고    scopus 로고
    • Belatacept and sirolimus prolong nonhuman primate islet allograft survival: Adverse consequences of concomitant alefacept therapy
    • Lowe MC, Badell IR, Turner AP, et al,. Belatacept and sirolimus prolong nonhuman primate islet allograft survival: adverse consequences of concomitant alefacept therapy. Am J Transplant 2013; 13: 312.
    • (2013) Am J Transplant , vol.13 , pp. 312
    • Lowe, M.C.1    Badell, I.R.2    Turner, A.P.3
  • 119
    • 84890802572 scopus 로고    scopus 로고
    • Targeting co-stimulatory pathways: Transplantation and autoimmunity
    • Ford ML, Adams AB, Pearson TC,. Targeting co-stimulatory pathways: transplantation and autoimmunity. Nat Rev Nephrol 2014; 10: 14.
    • (2014) Nat Rev Nephrol , vol.10 , pp. 14
    • Ford, M.L.1    Adams, A.B.2    Pearson, T.C.3
  • 120
    • 84930486514 scopus 로고    scopus 로고
    • Long-term outcome of belatacept therapy in de novo kidney transplant recipients - A case-match analysis
    • Schwarz C, Mayerhoffer S, Berlakovich GA, et al,. Long-term outcome of belatacept therapy in de novo kidney transplant recipients-a case-match analysis. Transpl Int 2015; 28: 820.
    • (2015) Transpl Int , vol.28 , pp. 820
    • Schwarz, C.1    Mayerhoffer, S.2    Berlakovich, G.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.