IL-15 preferentially enhances functional properties and antigen-specific responses of CD4+CD28 null compared to CD4+CD28+ T cells

Aging Cell

Volumn 10, Issue 5, 2011, Pages 844-852

  Alonso Arias, Rebeca ^a   Moro García, Marco A ^a   Vidal Castiñeira, José R ^a   Solano Jaurrieta, Juan J ^b   Suárez García, Francisco M ^c   Coto, Eliecer ^a,d   López Larrea, Carlos ^a,d  

^a HOSPITAL UNIVERSITARIO CENTRAL DE ASTURIAS   (Spain)

^b HOSPITAL MONTE NARANCO   (Spain)

^c Consejería de Salud y Servicios Sanitarios del Principado de Asturias ^*  (Spain)

^d Section of Nephrology   (Spain)

Author keywords

CD4+CD28 null T cells; Chronic viral antigens; Cytotoxicity; IL 15; Immunosenescence; Memory T cells

Indexed keywords

CD28 ANTIGEN; CD4 ANTIGEN; GAMMA INTERFERON; GRANZYME B; INTERLEUKIN 15; MESSENGER RNA; PERFORIN; STAT5 PROTEIN;

ANTIGEN EXPRESSION; ANTIGEN SPECIFICITY; ARTICLE; CELL AGING; CONTROLLED STUDY; CYTOKINE RELEASE; EFFECTOR CELL; HOST RESISTANCE; HUMAN; HUMAN CELL; INFECTION; LYMPHOCYTE PROLIFERATION; MEMORY T LYMPHOCYTE; PHENOTYPE; PRIORITY JOURNAL; T LYMPHOCYTE;

AGED; AGED, 80 AND OVER; ANTIBODIES, VIRAL; ANTIGENS, CD28; BIOLOGICAL MARKERS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; CYTOMEGALOVIRUS; GRANZYMES; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-15; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; PERFORIN; RECOMBINANT PROTEINS; RNA, MESSENGER; STAT5 TRANSCRIPTION FACTOR;

EID: 80052811310     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/j.1474-9726.2011.00725.x     Document Type: Article

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