-
1
-
-
21344438862
-
GABAergic dysfunction in schizophrenia: New treatment strategies on the horizon
-
[1][1] Guidotti, A.; Auta, J.; Davis, J.M.; Dong, E.; Grayson, D.R.; Veldic, M.; Zhang, X.; Costa, E. GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon. Psychopharmacology, 2005, 180, 191-205. http://dx.doi.org/10.1007/s00213-005-2212-8
-
(2005)
Psychopharmacology
, vol.180
, pp. 191-205
-
-
Guidotti, A.1
Auta, J.2
Davis, J.M.3
Dong, E.4
Grayson, D.R.5
Veldic, M.6
Zhang, X.7
Costa, E.8
-
2
-
-
84869087636
-
The dynamics of DNA methylation in schizophrenia and related psychiatric disorders
-
[2][2] Grayson, D.R.; Guidotti, A. The dynamics of DNA methylation in schizophrenia and related psychiatric disorders. Neuropsycho pharmacology, 2013, 38, 138-166. http://dx.doi.org/10.1038/npp.2012.125
-
(2013)
Neuropsycho Pharmacology
, vol.38
, pp. 138-166
-
-
Grayson, D.R.1
Guidotti, A.2
-
3
-
-
51649127761
-
Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation
-
U.S.A
-
[3][3] Dong, E.; Nelson, M.; Grayson, D.R.; Costa, E.; Guidotti, A. Clozapine and sulpiride but not haloperidol or olanzapine activate brain DNA demethylation Proc. Natl. Acad. Sci. U.S.A., 2008, 105, 13614-1369. http://dx.doi.org/10.1073/pnas.0805493105
-
(2008)
Natl. Acad. Sci
, vol.105
, pp. 13614-21369
-
-
Dong, E.1
Nelson, M.2
Grayson, D.R.3
Costa, E.4
Guidotti, A.5
-
4
-
-
59349098142
-
Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling
-
Guidotti A.; Dong, E.; Kundakovic, M.; Satta, R.; Grayson, D.R.; Costa, E. Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling. Trends Pharmacol. Sci., 2009, 30, 55-60. http://dx.doi.org/10.1016/j.tips.2008.10.010
-
(2009)
Trends Pharmacol. Sci.
, vol.30
, pp. 55-60
-
-
Guidotti, A.1
Dong, E.2
Kundakovic, M.3
Satta, R.4
Grayson, D.R.5
Costa, E.6
-
5
-
-
23044468380
-
The (Dual) origin of epigenetics. Cold Spring Harb
-
[5][5] Haig, D. The (dual) origin of epigenetics. Cold Spring Harb. Symp. Quant. Biol., 2004, 69, 67-70. http://dx.doi.org/10.1101/sqb.2004.69.67
-
(2004)
Symp. Quant. Biol.
, vol.69
, pp. 67-70
-
-
Haig, D.1
-
6
-
-
84925267221
-
Epigenetic inheritance: Histone bookmarks across generations
-
[6][6] Campos, E.I.; Stafford, J.M.; Reinberg, D. Epigenetic inheritance: histone bookmarks across generations. Trends Cell. Biol., 2014, 24, 664-674. http://dx.doi.org/10.1016/j.tcb.2014.08.004
-
(2014)
Trends Cell. Biol.
, vol.24
, pp. 664-674
-
-
Campos, E.I.1
Stafford, J.M.2
Reinberg, D.3
-
7
-
-
79952114038
-
Environmental epigenomics: Understanding the effects of parental care on the epigenome
-
[7][7] McGowan, P.O.; Szyf, M. Environmental epigenomics: understanding the effects of parental care on the epigenome. Essays Biochem., 2010, 48, 275-287. http://dx.doi.org/10.1042/bse0480275
-
(2010)
Essays Biochem.
, vol.48
, pp. 275-287
-
-
McGowan, P.O.1
Szyf, M.2
-
8
-
-
0032168678
-
CpG methylation, chromatin structure and gene silencing-a three-way connection
-
[8][8] Razin, A. CpG methylation, chromatin structure and gene silencing-a three-way connection. EMBO J., 1998, 17, 4905-4908. http://dx.doi.org/10.1093/emboj/17.17.4905
-
(1998)
EMBO J.
, vol.17
, pp. 4905-4908
-
-
Razin, A.1
-
9
-
-
0642306491
-
HIDden targets of microRNAs for growth control
-
[9][9] Bergmann, A.; Lane, M.E. HIDden targets of microRNAs for growth control. Trends Biochem Sci., 2003, 28, 461-463. http://dx.doi.org/10.1016/S0968-0004(03)00175-0
-
(2003)
Trends Biochem Sci.
, vol.28
, pp. 461-463
-
-
Bergmann, A.1
Lane, M.E.2
-
10
-
-
0032142918
-
Roles of histone acetyltransferases and deacetylases in gene regulation
-
[10][10] Kuo, M. H.; Allis, C.D. Roles of histone acetyltransferases and deacetylases in gene regulation. Bioessays, 1998, 20, 615-626. http://dx.doi.org/10.1002/(SICI)1521-1878(199808)20:8%3C615::AID-BIES4%3E3.0.CO;2-H
-
(1998)
Bioessays
, vol.20
, pp. 615-626
-
-
Kuo, M.H.1
Allis, C.D.2
-
11
-
-
84898645098
-
Epigenetic mechanisms of depression
-
[11][11] Nestler, E.J. Epigenetic mechanisms of depression. JAMA Psychiatry, 2014, 71, 454-456. http://dx.doi.org/10.1001/jamapsychiatry.2013.4291
-
(2014)
JAMA Psychiatry
, vol.71
, pp. 454-456
-
-
Nestler, E.J.1
-
12
-
-
33847325243
-
Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder
-
[12][12] Veldic, M.; Kadriu, B.; Maloku, E.; Agis-Balboa, R.C.; Guidotti, A.; Davis, J.M.; Costa, E. Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder. Schizophr Res., 2007, 91, 51-61. http://dx.doi.org/10.1016/j.schres.2006.11.029
-
(2007)
Schizophr Res.
, vol.91
, pp. 51-61
-
-
Veldic, M.1
Kadriu, B.2
Maloku, E.3
Agis-Balboa, R.C.4
Guidotti, A.5
Davis, J.M.6
Costa, E.7
-
13
-
-
0346636624
-
Epigenetic downregulation of GABAergic function in schizophrenia: Potential for pharmacological intervention?
-
[13][13] Costa, E.; Grayson, D.R.; Guidotti, A. Epigenetic downregulation of GABAergic function in schizophrenia: potential for pharmacological intervention? Mol. Interv., 2003, 3, 220-229. http://dx.doi.org/10.1124/mi.3.4.220
-
(2003)
Mol. Interv.
, vol.3
, pp. 220-229
-
-
Costa, E.1
Grayson, D.R.2
Guidotti, A.3
-
14
-
-
21544433777
-
Reelin promoter hypermethylation in schizophrenia
-
[14][14] Grayson, D.R.; Jia, X.; Chen, Y.; Sharma, R.P.; Mitchell, C.P.; Guidotti, A.; Costa, E. Reelin promoter hypermethylation in schizophrenia. Proc. Natl. Acad. Sci. U S A., 2005, 102, 9341-9346. http://dx.doi.org/10.1073/pnas.0503736102
-
(2005)
Proc. Natl. Acad. Sci. U S A.
, vol.102
, pp. 9341-9346
-
-
Grayson, D.R.1
Jia, X.2
Chen, Y.3
Sharma, R.P.4
Mitchell, C.P.5
Guidotti, A.6
Costa, E.7
-
15
-
-
2342509705
-
The origin of schizophrenia: Genetic thesis, epigenetic antithesis, and resolving synthesis
-
[15][15] Petronis, A. The origin of schizophrenia: genetic thesis, epigenetic antithesis, and resolving synthesis. Biol. Psychiatry, 2004, 55, 965-970.
-
(2004)
Biol. Psychiatry
, vol.55
, pp. 965-970
-
-
Petronis, A.1
-
16
-
-
42049120953
-
Epigenetics in mood disorders
-
[16][16] McGowan, P.O.; Kato T. Epigenetics in mood disorders. Environ Health Prev Med., 2008, 13, 16-24. http://dx.doi.org/10.1007/s12199-007-0002-0
-
(2008)
Environ Health Prev Med.
, vol.13
, pp. 16-24
-
-
McGowan, P.O.1
Kato, T.2
-
17
-
-
0023215296
-
Implications of normal brain development for the pathogenesis of schizophrenia
-
[17][17] Weinberger, D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry, 1987, 44, 660-669. http://dx.doi.org/10.1001/archpsyc.1987.01800190080012
-
(1987)
Arch. Gen. Psychiatry
, vol.44
, pp. 660-669
-
-
Weinberger, D.R.1
-
18
-
-
0033148776
-
Brain maturational processes and delayed onset in schizophrenia
-
[18][18] Keshavan, M.S.; Hogarty, G.E. Brain maturational processes and delayed onset in schizophrenia. Dev. Psychopathol., 1999, 11, 525-543. http://dx.doi.org/10.1017/S0954579499002199
-
(1999)
Dev. Psychopathol.
, vol.11
, pp. 525-543
-
-
Keshavan, M.S.1
Hogarty, G.E.2
-
19
-
-
65349191920
-
The neurodevelopmental hypothesis of schizophrenia, revisited
-
[19][19] Fatemi, S. h.; Folsom, T.D. The neurodevelopmental hypothesis of schizophrenia, revisited. Schizophr. Bull., 2009, 35, 528-548. http://dx.doi.org/10.1093/schbul/sbn187
-
(2009)
Schizophr. Bull.
, vol.35
, pp. 528-548
-
-
Fatemi, S.H.1
Folsom, T.D.2
-
20
-
-
79952283091
-
Prenatal stress: Role in psychotic and depressive diseases
-
[20][20] Markham, J.A.; Koenig, J I. Prenatal stress: role in psychotic and depressive diseases. Psychopharmacology, 2011, 214, 89-106. http://dx.doi.org/10.1007/s00213-010-2035-0
-
(2011)
Psychopharmacology
, vol.214
, pp. 89-106
-
-
Markham, J.A.1
Koenig, J.I.2
-
21
-
-
38949120901
-
Higher risk of offspring schizophrenia following antenatal maternal exposure to severe adverse life events
-
[21][21] Khashan, A.S.; Abel, K.M.; McNamee, R.; Pedersen, M.G.; Webb, R.T.; Baker, P.N.; Kenny, L.C.; Mortensen, P.B. Higher risk of offspring schizophrenia following antenatal maternal exposure to severe adverse life events. Arch. Gen. Psychiatry, 2008, 65, 146-152. http://dx.doi.org/10.1001/archgenpsychiatry.2007.20
-
(2008)
Arch. Gen. Psychiatry
, vol.65
, pp. 146-152
-
-
Khashan, A.S.1
Abel, K.M.2
McNamee, R.3
Pedersen, M.G.4
Webb, R.T.5
Baker, P.N.6
Kenny, L.C.7
Mortensen, P.B.8
-
22
-
-
84874355139
-
Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice
-
[22][22] Giovanoli, S.; Engler, H.; Engler, A.; Richetto, J.; Voget, M.; Willi, R.; Winter, C.; Riva, M.A.; Mortensen, P.B.; Feldon, J.; Schedlowski, M.; Meyer, U. Stress in puberty unmasks latent neuropathological consequences of prenatal immune activation in mice. Science, 2013, 339, 1095-1099. http://dx.doi.org/10.1126/science.1228261
-
(2013)
Science
, vol.339
, pp. 1095-1099
-
-
Giovanoli, S.1
Engler, H.2
Engler, A.3
Richetto, J.4
Voget, M.5
Willi, R.6
Winter, C.7
Riva, M.A.8
Mortensen, P.B.9
Feldon, J.10
Schedlowski, M.11
Meyer, U.12
-
23
-
-
84875221641
-
Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice
-
[23][23] Matrisciano, F.; Tueting, P.; Dalal, I.; Kadriu, B.; Grayson, D.R.; Davis, J.M.; Nicoletti, F.; Guidotti, A. Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice. Neuropharmacology, 2013, 68, 184-194. http://dx.doi.org/10.1016/j.neuropharm.2012.04.013
-
(2013)
Neuropharmacology
, vol.68
, pp. 184-194
-
-
Matrisciano, F.1
Tueting, P.2
Dalal, I.3
Kadriu, B.4
Grayson, D.R.5
Davis, J.M.6
Nicoletti, F.7
Guidotti, A.8
-
24
-
-
84875052807
-
Prenatal stress delays inhibitory neuron progenitor migration in the developing neocortex
-
[24][24] Stevens, H.E.; Su, T.; Yanagawa, Y.; Vaccarino, F.M. Prenatal stress delays inhibitory neuron progenitor migration in the developing neocortex. Psychoneuroendocrinology, 2013, 38, 509-521. http://dx.doi.org/10.1016/j.psyneuen.2012.07.011
-
(2013)
Psychoneuroendocrinology
, vol.38
, pp. 509-521
-
-
Stevens, H.E.1
Su, T.2
Yanagawa, Y.3
Vaccarino, F.M.4
-
25
-
-
84901265241
-
Prenatal stress and inhibitory neuron systems: Implications for neuropsychiatric disorders
-
[25][25] Fine, R.; Zhang, J.; Stevens H E. Prenatal stress and inhibitory neuron systems: implications for neuropsychiatric disorders. Mol. Psychiatry, 2014, 19, 641-651. http://dx.doi.org/10.1038/mp.2014.35
-
(2014)
Mol. Psychiatry
, vol.19
, pp. 641-651
-
-
Fine, R.1
Zhang, J.2
Stevens, H.E.3
-
26
-
-
42749095376
-
Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia
-
[26][26] Lisman, J.E.; Coyle, J.T.; Green, R.W.; Javitt, D.C.; Benes, F.M.; Heckers, S.; Grace, A.A. Circuit-based framework for understanding neurotransmitter and risk gene interactions in schizophrenia. Trends Neurosci., 2008, 31, 234-242. http://dx.doi.org/10.1016/j.tins.2008.02.005
-
(2008)
Trends Neurosci.
, vol.31
, pp. 234-242
-
-
Lisman, J.E.1
Coyle, J.T.2
Green, R.W.3
Javitt, D.C.4
Benes, F.M.5
Heckers, S.6
Grace, A.A.7
-
27
-
-
54149109208
-
GABA neurons and the mechanisms of network oscillations: Implications for understanding cortical dysfunction in schizophrenia. Schizophr
-
[27][27] Gonzalez-Burgos, G.; Lewis, D.A. GABA neurons and the mechanisms of network oscillations: implications for understanding cortical dysfunction in schizophrenia. Schizophr. Bull., 2008, 34, 944-961. http://dx.doi.org/10.1093/schbul/sbn070
-
(2008)
Bull.
, vol.34
, pp. 944-961
-
-
Gonzalez-Burgos, G.1
Lewis, D.A.2
-
28
-
-
84905273415
-
Association of aberrant neural synchrony and altered GAD67 expression following exposure to maternal immune activation, a risk factor for schizophrenia
-
[28][28] Dickerson, D.D.; Overeem, KA.; Wolff, A.R.; Williams, J.M.; Abraham, W.C.; Bilkey, D.K. Association of aberrant neural synchrony and altered GAD67 expression following exposure to maternal immune activation, a risk factor for schizophrenia. Transl. Psychiatry, 2014, 4, 418. http://dx.doi.org/10.1038/tp.2014.64
-
(2014)
Transl. Psychiatry
, vol.4
, pp. 418
-
-
Dickerson, D.D.1
Overeem, K.A.2
Wolff, A.R.3
Williams, J.M.4
Abraham, W.C.5
Bilkey, D.K.6
-
29
-
-
84857057482
-
Pharmacological activation of group-II metabotropic glutamate receptors corrects a schizophrenia-like phenotype induced by prenatal stress in mice
-
[29][29] Matrisciano, F.; Tueting, P.; Maccari, S.; Nicoletti, F.; Guidotti, A. Pharmacological activation of group-II metabotropic glutamate receptors corrects a schizophrenia-like phenotype induced by prenatal stress in mice. Neuropsychopharmacology, 2012, 37, 929-938. http://dx.doi.org/10.1038/npp.2011.274
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 929-938
-
-
Matrisciano, F.1
Tueting, P.2
Maccari, S.3
Nicoletti, F.4
Guidotti, A.5
-
30
-
-
84923066332
-
Brain-Derived Neurotrophic Factor Epigenetic Modifications Associated with Schizophrenia-like Phenotype Induced by Prenatal Stress in Mice. Biol
-
pii: S0006-3223(14)00634-9
-
[30][30] Dong, E.; Dzitoyeva, S.G.; Matrisciano, F.; Tueting, P.; Grayson, D.R.; Guidotti, A. Brain-Derived Neurotrophic Factor Epigenetic Modifications Associated with Schizophrenia-like Phenotype Induced by Prenatal Stress in Mice. Biol. Psychiatry, 2015, 77, 589-596. pii: S0006-3223(14)00634-9.
-
(2015)
Psychiatry
, vol.77
, pp. 589-596
-
-
Dong, E.1
Dzitoyeva, S.G.2
Matrisciano, F.3
Tueting, P.4
Grayson, D.R.5
Guidotti, A.6
-
31
-
-
84942091930
-
DNAmethyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients
-
pii: S0920-9964(14)00599-4
-
[31][31] Dong, E., Ruzicka, W.B.; Grayson, D.R.; Guidotti, A. DNAmethyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients. Schizophr. Res., 2015, 167, 35-41. pii: S0920-9964(14)00599-4.
-
(2015)
Schizophr. Res.
, vol.167
, pp. 35-41
-
-
Dong, E.1
Ruzicka, W.B.2
Grayson, D.R.3
Guidotti, A.4
-
32
-
-
84869097686
-
Epigenetics in the human brain
-
[32][32] Houston, I.; Peter, C.J.; Mitchell, A.; Straubhaar, J.; Rogaev, E.; Akbarian, S. Epigenetics in the human brain. Neuropsychopharmacology, 2013, 38, 183-197. http://dx.doi.org/10.1038/npp.2012.78
-
(2013)
Neuropsychopharmacology
, vol.38
, pp. 183-197
-
-
Houston, I.1
Peter, C.J.2
Mitchell, A.3
Straubhaar, J.4
Rogaev, E.5
Akbarian, S.6
-
33
-
-
79954612114
-
Epigenetic GABAergic targets in schizophrenia and bipolar disorder
-
[33][33] Guidotti, A.; Auta, J.; Chen, Y.; Davis, J.M.; Dong, E.; Gavin, D.P.; Grayson, D.R.; Matrisciano, F.; Pinna, G.; Satta, R.; Sharma, R.P.; Tremolizzo, L.; Tueting, P. Epigenetic GABAergic targets in schizophrenia and bipolar disorder. Neuropharmacology, 2011, 60, 1007-1016. http://dx.doi.org/10.1016/j.neuropharm.2010.10.021
-
(2011)
Neuropharmacology
, vol.60
, pp. 1007-1016
-
-
Guidotti, A.1
Auta, J.2
Chen, Y.3
Davis, J.M.4
Dong, E.5
Gavin, D.P.6
Grayson, D.R.7
Matrisciano, F.8
Pinna, G.9
Satta, R.10
Sharma, R.P.11
Tremolizzo, L.12
Tueting, P.13
-
34
-
-
41149140859
-
Epigenomic profiling reveals DNAmethylation changes associated with major psychosis
-
[34][34] Mill, J.; Tang, T.; Kaminsky, Z.; Khare, T.; Yazdanpanah, S.; Bouchard, L.; Jia, P.; Assadzadeh, A.; Flanagan, J.; Schumacher, A., Wang, S.C.; Petronis, A. Epigenomic profiling reveals DNAmethylation changes associated with major psychosis. Am. J. Hum. Genet., 2008, 82, 696-711. http://dx.doi.org/10.1016/j.ajhg.2008.01.008
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 696-711
-
-
Mill, J.1
Tang, T.2
Kaminsky, Z.3
Khare, T.4
Yazdanpanah, S.5
Bouchard, L.6
Jia, P.7
Assadzadeh, A.8
Flanagan, J.9
Schumacher, A.10
Wang, S.C.11
Petronis, A.12
-
35
-
-
84875774639
-
Genetics of schizophrenia: What do we know
-
[35][35] Zhang, J.P.; Malhotra, A.K. Genetics of schizophrenia: What do we know? Curr. Psychiatr., 2013, 12, 24-33.
-
(2013)
Curr. Psychiatr.
, vol.12
, pp. 24-33
-
-
Zhang, J.P.1
Malhotra, A.K.2
-
36
-
-
84859499394
-
Epigenetic and post-transcriptional dysregulation of gene expression in schizophrenia and related disease
-
[36][36] Gavin, D.P.; Akbarian, S. Epigenetic and post-transcriptional dysregulation of gene expression in schizophrenia and related disease. Neurobiol. Dis., 2012, 46, 255-262. http://dx.doi.org/10.1016/j.nbd.2011.12.008
-
(2012)
Neurobiol. Dis.
, vol.46
, pp. 255-262
-
-
Gavin, D.P.1
Akbarian, S.2
-
37
-
-
84866104895
-
Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients. Transl
-
[37][37] Dong, E.; Gavin, D.P.; Chen, Y.; Davis, J. Upregulation of TET1 and downregulation of APOBEC3A and APOBEC3C in the parietal cortex of psychotic patients. Transl. Psychiatry, 2012, 2, 159. http://dx.doi.org/10.1038/tp.2012.86
-
(2012)
Psychiatry
, vol.2
, pp. 159
-
-
Dong, E.1
Gavin, D.P.2
Chen, Y.3
Davis, J.4
-
38
-
-
84901400390
-
Toward the identification of peripheral epigenetic biomarkers of schizophrenia
-
[38][38] Guidotti, A.; Auta, J.; Davis, J.M.; Dong, E.; Gavin, D.P.; Grayson, D.R.; Sharma, R.P.; Smith, R.C.; Tueting, P.; Zhubi, A. Toward the identification of peripheral epigenetic biomarkers of schizophrenia. J. Neurogenet., 2014, 28, 41-52. http://dx.doi.org/10.3109/01677063.2014.892485
-
(2014)
J. Neurogenet.
, vol.28
, pp. 41-52
-
-
Guidotti, A.1
Auta, J.2
Davis, J.M.3
Dong, E.4
Gavin, D.P.5
Grayson, D.R.6
Sharma, R.P.7
Smith, R.C.8
Tueting, P.9
Zhubi, A.10
-
39
-
-
84892609862
-
Prenatal poly(I:C) exposure and other developmental immune activation models in rodent systems. Biol
-
[39][39] Meyer, U. Prenatal poly(i:C) exposure and other developmental immune activation models in rodent systems. Biol. Psychiatry, 2014, 75, 307-315. http://dx.doi.org/10.1016/j.biopsych.2013.07.011
-
(2014)
Psychiatry
, vol.75
, pp. 307-315
-
-
Meyer, U.1
-
40
-
-
84889092626
-
Evidences for a progressive microglial activation and increase in iNOS expression in rats submitted to a neurodevelopmental model of schizophrenia: Reversal by clozapine
-
[40][40] Ribeiro, B.M.; do Carmo, M.R.; Freire, R.S.; Rocha, N.F.; Borella, V.C.; de Menezes, A.T.; Monte, A.S.; Gomes, P.X.; de Sousa, F.C., Vale, M.L.; de Lucena, D.F.; Gama, C.S.; Macedo, D. Evidences for a progressive microglial activation and increase in iNOS expression in rats submitted to a neurodevelopmental model of schizophrenia: reversal by clozapine. Schizophr. Res., 2013, 151, 12-19. http://dx.doi.org/10.1016/j.schres.2013.10.040
-
(2013)
Schizophr. Res.
, vol.151
, pp. 12-19
-
-
Ribeiro, B.M.1
Do Carmo, M.R.2
Freire, R.S.3
Rocha, N.F.4
Borella, V.C.5
De Menezes, A.T.6
Monte, A.S.7
Gomes, P.X.8
De Sousa, F.C.9
Vale, M.L.10
De Lucena, D.F.11
Gama, C.S.12
Macedo, D.13
-
41
-
-
79954614494
-
Metabotropic glutamate receptors: From the workbench to the bedside
-
[41][41] Nicoletti, F.; Bockaert, J.; Collingridge, G.L.; Conn, P.J.; Ferraguti, F.; Schoepp D.D.; Wroblewski, J.T.; Pin, J.P. Metabotropic glutamate receptors: from the workbench to the bedside. Neuropharmacology, 2011, 60, 1017-1041. http://dx.doi.org/10.1016/j.neuropharm.2010.10.022
-
(2011)
Neuropharmacology
, vol.60
, pp. 1017-1041
-
-
Nicoletti, F.1
Bockaert, J.2
Collingridge, G.L.3
Conn, P.J.4
Ferraguti, F.5
Schoepp, D.D.6
Wroblewski, J.T.7
Pin, J.P.8
-
42
-
-
0011900802
-
Preclinical pharmacology of mGlu2/3 receptor agonists: Novel agents for schizophrenia
-
(Schoepp) DD, D.D
-
[42][42] (Schoepp) DD, D.D.; Marek, G.J. Preclinical pharmacology of mGlu2/3 receptor agonists: novel agents for schizophrenia? Curr. Drug Targets CNS Neurol. Disord., 2002, 1, 215-225. http://dx.doi.org/10.2174/1568007024606177
-
(2002)
Curr. Drug Targets CNS Neurol. Disord.
, vol.1
, pp. 215-225
-
-
Marek, G.J.1
-
43
-
-
0034068655
-
Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine
-
[43][43] Cartmell, J.; Monn, J.A.; Schoepp, D.D. Attenuation of specific PCP-evoked behaviors by the potent mGlu2/3 receptor agonist, LY379268 and comparison with the atypical antipsychotic, clozapine. Psychopharmacology, 2000, 148, 423-429. http://dx.doi.org/10.1007/s002130050072
-
(2000)
Psychopharmacology
, vol.148
, pp. 423-429
-
-
Cartmell, J.1
Monn, J.A.2
Schoepp, D.D.3
-
44
-
-
0034698431
-
The mGlu(2/3) receptor agonist LY379268 selectively blocks amphetamine ambulations and rearing
-
[44][44] Cartmell, J.; Monn, J.A.; Schoepp, D.D. The mGlu(2/3) receptor agonist LY379268 selectively blocks amphetamine ambulations and rearing. Eur. J. Pharmacol., 2000, 400, 221-224. http://dx.doi.org/10.1016/S0014-2999(00)00423-4
-
(2000)
Eur. J. Pharmacol.
, vol.400
, pp. 221-224
-
-
Cartmell, J.1
Monn, J.A.2
Schoepp, D.D.3
-
45
-
-
0032575715
-
Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats
-
[45][45] Moghaddam, B.; Adams, B.W. Reversal of phencyclidine effects by a group II metabotropic glutamate receptor agonist in rats. Science, 1998, 281, 1349-1352. http://dx.doi.org/10.1126/science.281.5381.1349
-
(1998)
Science
, vol.281
, pp. 1349-1352
-
-
Moghaddam, B.1
Adams, B.W.2
-
46
-
-
84858001721
-
MGluR3 and not mGluR2 receptors mediate the efficacy of NAAG peptidase inhibitor in validated model of schizophrenia. Schizophr
-
[46][46] Olszewski, R.T.; Bzdega, T.; Neale, J.H. mGluR3 and not mGluR2 receptors mediate the efficacy of NAAG peptidase inhibitor in validated model of schizophrenia. Schizophr. Res., 2012, 136, 160-161. http://dx.doi.org/10.1016/j.schres.2012.01.007
-
(2012)
Res.
, vol.136
, pp. 160-161
-
-
Olszewski, R.T.1
Bzdega, T.2
Neale, J.H.3
-
47
-
-
9644281163
-
The mGlu2/3 receptor agonist LY379268 injected into cortex or thalamus decreases neuronal injury in retrosplenial cortex produced by NMDA receptor antagonist MK-801: Possible implications for psychosis
-
[47][47] Carter, K.; Dickerson, J.; Schoepp, D.D.; Reilly, M.; Herring, N.; Williams, J.; Sallee, F.R.; Sharp, J.W.; Sharp, F.R. The mGlu2/3 receptor agonist LY379268 injected into cortex or thalamus decreases neuronal injury in retrosplenial cortex produced by NMDA receptor antagonist MK-801: possible implications for psychosis. Neuropharmacology, 2004, 47, 1135-1145. http://dx.doi.org/10.1016/j.neuropharm.2004.08.018
-
(2004)
Neuropharmacology
, vol.47
, pp. 1135-1145
-
-
Carter, K.1
Dickerson, J.2
Schoepp, D.D.3
Reilly, M.4
Herring, N.5
Williams, J.6
Sallee, F.R.7
Sharp, J.W.8
Sharp, F.R.9
-
48
-
-
82955198413
-
Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission
-
[48][48] Ago, Y.; Araki, R.; Yano, K.; Hiramatsu, N.; Kawasaki, T.; Chaki, S.; Nakazato, A.; Onoe, H.; Hashimoto, H.; Baba, A.; Takuma, K.; Matsuda, T. Activation of metabotropic glutamate 2/3 receptors attenuates methamphetamine-induced hyperlocomotion and increase in prefrontal serotonergic neurotransmission. Psychopharmacology, 2011, 217, 443-452. http://dx.doi.org/10.1124/mol.107.035170
-
(2011)
Psychopharmacology
, vol.217
, pp. 443-452
-
-
Ago, Y.1
Araki, R.2
Yano, K.3
Hiramatsu, N.4
Kawasaki, T.5
Chaki, S.6
Nakazato, A.7
Onoe, H.8
Hashimoto, H.9
Baba, A.10
Takuma, K.11
Matsuda, T.12
-
49
-
-
34547198448
-
Selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis
-
[49][49] Benneyworth, M.A.; Xiang, Z.; Smith, R.L.; Garcia, E.E.; Conn, P.J.; Sanders-Bush, E. A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis. Mol. Pharmacol., 2007, 72, 477-484. http://dx.doi.org/10.1124/mol.107.035170
-
(2007)
Mol. Pharmacol.
, vol.72
, pp. 477-484
-
-
Benneyworth, M.A.1
Xiang, Z.2
Smith, R.L.3
Garcia, E.E.4
Conn, P.J.5
Sanders-Bush, E.A.6
-
50
-
-
0033981186
-
Physiological antagonism between 5-hydroxytryptamine(2A) and group II metabotropic glutamate receptors in prefrontal cortex
-
[50][50] Marek, G.J.; Wright, R.A.; Schoepp, D.D.; Monn, J.A.; Aghajanian, G.K. Physiological antagonism between 5-hydroxytryptamine(2A) and group II metabotropic glutamate receptors in prefrontal cortex. J. Pharmacol. Exp. Ther., 2000, 292, 76-87.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.292
, pp. 76-87
-
-
Marek, G.J.1
Wright, R.A.2
Schoepp, D.D.3
Monn, J.A.4
Aghajanian, G.K.5
-
51
-
-
1642410058
-
Serotonergic/glutamatergic interactions: The effects of mGlu2/3 receptor ligands in rats trained with LSD and PCP as discriminative stimuli
-
[51][51] Winter, J.C.; Eckler, J.R.; Rabin, R.A. Serotonergic/glutamatergic interactions: the effects of mGlu2/3 receptor ligands in rats trained with LSD and PCP as discriminative stimuli. Psychopharmacology, 2004, 172, 233-240. http://dx.doi.org/10.1007/s00213-003-1636-2
-
(2004)
Psychopharmacology
, vol.172
, pp. 233-240
-
-
Winter, J.C.1
Eckler, J.R.2
Rabin, R.A.3
-
52
-
-
84871760600
-
Gonzalez-Maeso, J. Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5- HT2A・mGlu2) receptor heteromerization and its psychoactive behavioral function
-
[52][52] Moreno, J.L.; Muguruza, C.; Umali, A.; Mortillo, S.; Holloway, T.; Pilar-Cuellar, F.; Mocci, G.; Seto, J.; Callado, L.F.; Neve, R.L.; Milligan, G.; Sealfon, S.C.; Lopez-Gimenez, J.F., Meana, J.J.; Benson, D.L.; Gonzalez-Maeso, J. Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5- HT2A・mGlu2) receptor heteromerization and its psychoactive behavioral function. J. Biol. Chem., 2012, 287, 44301-44319 http://dx.doi.org/10.1074/jbc.M112.413161
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 44301-44319
-
-
Moreno, J.L.1
Muguruza, C.2
Umali, A.3
Mortillo, S.4
Holloway, T.5
Pilar-Cuellar, F.6
Mocci, G.7
Seto, J.8
Callado, L.F.9
Neve, R.L.10
Milligan, G.11
Sealfon, S.C.12
Lopez-Gimenez, J.F.13
Meana, J.J.14
Benson, D.L.15
-
53
-
-
34948858402
-
Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: A randomized Phase 2 clinical trial
-
[53][53] Patil, S.T.; Zhang, L.; Martenyi, F.; Lowe, S.L.; Jackson, K.A.; Andreev, B.V.; Avedisova, A.S.; Bardenstein, L.M.; Gurovich, I.Y.; Morozova, M.A.; Mosolov, S.N.; Neznanov, N.G.; Reznik, A.M.; Smulevich, A.B.; Tochilov, V.A.; Johnson, B.G.; Monn, J.A.; Schoepp, D.D. Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial. Nat. Med., 2007, 13, 1102-1107. http://dx.doi.org/10.1038/nm1632
-
(2007)
Nat. Med.
, vol.13
, pp. 1102-1107
-
-
Patil, S.T.1
Zhang, L.2
Martenyi, F.3
Lowe, S.L.4
Jackson, K.A.5
Andreev, B.V.6
Avedisova, A.S.7
Bardenstein, L.M.8
Gurovich, I.Y.9
Morozova, M.A.10
Mosolov, S.N.11
Neznanov, N.G.12
Reznik, A.M.13
Smulevich, A.B.14
Tochilov, V.A.15
Johnson, B.G.16
Monn, J.A.17
Schoepp, D.D.18
-
54
-
-
79955594301
-
HBBI Study Group. A multicenter, inpatient, phase 2, double-blind, placebo-controlled dose-ranging study of LY2140023 monohydrate in patients with DSM-IV schizophrenia
-
Kinon, B.J.; Zhang, L.; Millen, B.A.; Osuntokun, O.O.; Williams, J.E.; Kollack-Walker, S.; Jackson, K.; Kryzhanovskaya, L.; Jarkova, N.; HBBI Study Group. A multicenter, inpatient, phase 2, double-blind, placebo-controlled dose-ranging study of LY2140023 monohydrate in patients with DSM-IV schizophrenia. J. Clin. Psychopharmacol., 2011, 31, 349-355. http://dx.doi.org/10.1097/JCP.0b013e318218dcd5
-
(2011)
J. Clin. Psychopharmacol.
, vol.31
, pp. 349-355
-
-
Kinon, B.J.1
Zhang, L.2
Millen, B.A.3
Osuntokun, O.O.4
Williams, J.E.5
Kollack-Walker, S.6
Jackson, K.7
Kryzhanovskaya, L.8
Jarkova, N.9
-
55
-
-
84886304673
-
Pomaglumetad methionil: No significant difference as an adjunctive treatment for patients with prominent negative symptoms of schizophrenia compared to placebo
-
[55][55] Stauffer, V.L.; Millen, B.A.; Andersen, S.; Kinon, B.J., Lagrandeur, L.; Lindenmayer, J.P.; Gomez, J.C. Pomaglumetad methionil: no significant difference as an adjunctive treatment for patients with prominent negative symptoms of schizophrenia compared to placebo. Schizophr. Res., 2013, 150, 434-441. http://dx.doi.org/10.1016/j.schres.2013.08.020
-
(2013)
Schizophr. Res.
, vol.150
, pp. 434-441
-
-
Stauffer, V.L.1
Millen, B.A.2
Andersen, S.3
Kinon, B.J.4
Lagrandeur, L.5
Lindenmayer, J.P.6
Gomez, J.C.7
-
56
-
-
84866141733
-
HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity
-
[56][56] Kurita, M.; Holloway, T.; Garcia-Bea, A.; Kozlenkov, A.; Friedman, A.K.; Moreno, J.L.; Heshmati, M.; Golden, S.A.; Kennedy, P.J.; Takahashi, N.; Dietz, D.M.; Mocci, G.; Gabilondo, A.M.; Hanks, J.; Umali, A.; Callado, L.F.; Gallitano, A.L.; Neve, R.L.; Shen, L.; Buxbaum, J.D.; Han, M. H.; Nestler, E.J.; Meana, J.J.; Russo, S.J.; Gonzalez-Maeso, J. HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity. Nat. Neurosci., 2012, 15, 1245-1254. http://dx.doi.org/10.1038/nn.3181
-
(2012)
Nat. Neurosci.
, vol.15
, pp. 1245-1254
-
-
Kurita, M.1
Holloway, T.2
Garcia-Bea, A.3
Kozlenkov, A.4
Friedman, A.K.5
Moreno, J.L.6
Heshmati, M.7
Golden, S.A.8
Kennedy, P.J.9
Takahashi, N.10
Dietz, D.M.11
Mocci, G.12
Gabilondo, A.M.13
Hanks, J.14
Umali, A.15
Callado, L.F.16
Gallitano, A.L.17
Neve, R.L.18
Shen, L.19
Buxbaum, J.D.20
Han, M.H.21
Nestler, E.J.22
Meana, J.J.23
Russo, S.J.24
Gonzalez-Maeso, J.25
more..
-
57
-
-
84877825156
-
Repressive epigenetic changes at the mGlu2 promoter in frontal cortex of 5-HT2A knockout mice. Mol
-
[57][57] Kurita, M.; Moreno, J.L.; Holloway, T.; Kozlenkov, A.; Mocci, G.; García-Bea, A.; Hanks, J.B.; Neve, R.; Nestler, E.J.; Russo, S.J.; González-Maeso, J. Repressive epigenetic changes at the mGlu2 promoter in frontal cortex of 5-HT2A knockout mice. Mol. Pharmacol., 2013, 83, 1166-1175. http://dx.doi.org/10.1124/mol.112.084582
-
(2013)
Pharmacol.
, vol.83
, pp. 1166-1175
-
-
Kurita, M.1
Moreno, J.L.2
Holloway, T.3
Kozlenkov, A.4
Mocci, G.5
García-Bea, A.6
Hanks, J.B.7
Neve, R.8
Nestler, E.J.9
Russo, S.J.10
González-Maeso, J.11
-
58
-
-
79959320022
-
Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain
-
[58][58] Matrisciano, F.; Dong, E.; Gavin, D.P.; Nicoletti, F.; Guidotti, A. Activation of group II metabotropic glutamate receptors promotes DNA demethylation in the mouse brain. Mol. Pharmacol., 2011, 80, 174-182. http://dx.doi.org/10.1124/mol.110.070896
-
(2011)
Mol. Pharmacol.
, vol.80
, pp. 174-182
-
-
Matrisciano, F.1
Dong, E.2
Gavin, D.P.3
Nicoletti, F.4
Guidotti, A.5
-
59
-
-
0035965343
-
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
-
[59][59] Phiel, C.J.; Zhang, F.; Huang, E.Y.; Guenther, M.G.; Lazar, M.A.; Klein, P.S. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J. Biol. Chem., 2001, 276, 36734-36741. http://dx.doi.org/10.1074/jbc.M101287200
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 36734-36741
-
-
Phiel, C.J.1
Zhang, F.2
Huang, E.Y.3
Guenther, M.G.4
Lazar, M.A.5
Klein, P.S.6
-
60
-
-
0034055690
-
Serotonin model of schizophrenia: Emerging role of glutamate mechanisms
-
[60][60] Aghajanian, G.K.; Marek, G.J. Serotonin model of schizophrenia: emerging role of glutamate mechanisms. Brain Res. Brain Res. Rev., 2000, 31, 302-312. http://dx.doi.org/10.1016/S0165-0173(99)00046-6
-
(2000)
Brain Res. Brain Res. Rev.
, vol.31
, pp. 302-312
-
-
Aghajanian, G.K.1
Marek, G.J.2
-
61
-
-
40449139964
-
Identification of a serotonin/glutamate receptor complex implicated in psychosis
-
[61][61] González-Maeso, J.; Ang, R.L.; Yuen, T.; Chan, P.; Weisstaub, N.V.; Lopez-Giménez, J.F.; Zhou, M.; Okawa, Y.; Callado, L.F.; Milligan, G.; Gingrich, J.A.; Filizola, M.; Meana, J.J.; Sealfon, S.C. Identification of a serotonin/glutamate receptor complex implicated in psychosis. Nature, 2008, 452, 93-97. http://dx.doi.org/10.1038/nature06612
-
(2008)
Nature
, vol.452
, pp. 93-97
-
-
González-Maeso, J.1
Ang, R.L.2
Yuen, T.3
Chan, P.4
Weisstaub, N.V.5
Lopez-Giménez, J.F.6
Zhou, M.7
Okawa, Y.8
Callado, L.F.9
Milligan, G.10
Gingrich, J.A.11
Filizola, M.12
Meana, J.J.13
Sealfon, S.C.14
-
62
-
-
81855189491
-
Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs
-
[62][62] Fribourg, M.; Moreno, J.L.; Holloway, T.; Provasi, D.; Baki, L.; Mahajan, R.; Park, G.; Adney, S.K.; Hatcher, C.; Eltit, J.M.; Ruta, J.D.; Albizu, L.; Li, Z.; Umali, A.; Shim, J.; Fabiato, A.; MacKerell, A.D. Jr.; Brezina, V.; Sealfon, S.C.; Filizola, M.; Gonzalez-Maeso, J.; Logothetis, D.E. Decoding the signaling of a GPCR heteromeric complex reveals a unifying mechanism of action of antipsychotic drugs. Cell, 2011, 147, 1011-1023. http://dx.doi.org/10.1016/j.cell.2011.09.055
-
(2011)
Cell
, vol.147
, pp. 1011-1023
-
-
Fribourg, M.1
Moreno, J.L.2
Holloway, T.3
Provasi, D.4
Baki, L.5
Mahajan, R.6
Park, G.7
Adney, S.K.8
Hatcher, C.9
Eltit, J.M.10
Ruta, J.D.11
Albizu, L.12
Li, Z.13
Umali, A.14
Shim, J.15
Fabiato, A.16
Mackerell, A.D.17
Brezina, V.18
Sealfon, S.C.19
Filizola, M.20
Gonzalez-Maeso, J.21
Logothetis, D.E.22
more..
-
63
-
-
84871760600
-
Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5- HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral function
-
[63][63] Moreno, J.L.; Muguruza, C.; Umali, A.; Mortillo, S.; Holloway, T.; Pilar-Cuéllar, F.; Mocci, G.; Seto, J.; Callado, L.F.; Neve, R.L.; Milligan, G.; Sealfon, S.C.; López-Giménez, J.F.; Meana, J.J.; Benson, D.L.; Gonzalez-Maeso, J. Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5- HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral function. J. Biol. Chem., 2012, 287, 44301-44319. http://dx.doi.org/10.1074/jbc.M112.413161
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 44301-44319
-
-
Moreno, J.L.1
Muguruza, C.2
Umali, A.3
Mortillo, S.4
Holloway, T.5
Pilar-Cuéllar, F.6
Mocci, G.7
Seto, J.8
Callado, L.F.9
Neve, R.L.10
Milligan, G.11
Sealfon, S.C.12
López-Giménez, J.F.13
Meana, J.J.14
Benson, D.L.15
Gonzalez-Maeso, J.16
-
64
-
-
79551541660
-
Maternal influenza viral infection causes schizophrenia-like alterations of 5-HT
-
2 receptors in the adult offspring. J. Neurosci., 2011, 31, 1863-1872. http://dx.doi.org/10.1523/JNEUROSCI.4230-10.2011
-
(2011)
J. Neurosci.
, vol.31
, pp. 1863-1872
-
-
Moreno, J.L.1
Kurita, M.2
Holloway, T.3
Lopez, J.4
Cadagan, R.5
Martinez-Sobrido, L.6
Garcia-Sastre, A.7
Gonzalez-Maeso, J.8
-
65
-
-
84872352078
-
Prenatal stress induces schizophrenia-like alterations of serotonin 2A and metabotropic glutamate 2 receptors in the adult offspring: Role of maternal immune syste
-
[65][65] Holloway, T.; Moreno, J.L.; Umali, A.; Rayannavar, V.; Hodes, G.E.; Russo, S.J.; González-Maeso J. Prenatal stress induces schizophrenia-like alterations of serotonin 2A and metabotropic glutamate 2 receptors in the adult offspring: role of maternal immune syste. J. Neurosci., 2013, 33, 1088-1098. http://dx.doi.org/10.1523/JNEUROSCI.2331-12.2013
-
(2013)
J. Neurosci.
, vol.33
, pp. 1088-1098
-
-
Holloway, T.1
Moreno, J.L.2
Umali, A.3
Rayannavar, V.4
Hodes, G.E.5
Russo, S.J.6
González-Maeso, J.7
-
66
-
-
18344385695
-
L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors
-
[66][66] Chiechio, S.; Caricasole, A.; Barletta, E.; Storto, M.; Catania, M.V.; Copani, A.; Vertechy, M.; Nicolai, R.; Calvani, M.; Melchiorri, D.; Nicoletti, F. L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors. Mol. Pharmacol., 2002, 61, 989-996. http://dx.doi.org/10.1124/mol.61.5.989
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 989-996
-
-
Chiechio, S.1
Caricasole, A.2
Barletta, E.3
Storto, M.4
Catania, M.V.5
Copani, A.6
Vertechy, M.7
Nicolai, R.8
Calvani, M.9
Melchiorri, D.10
Nicoletti, F.11
-
67
-
-
77950537328
-
Transcriptional regulation of type-2 metabotropic glutamate receptors: An epigenetic path to novel treatments for chronic pain
-
[67][67] Chiechio, S.; Copani, A.; Zammataro, M.; Battaglia, G.; Gereau, R.W. 4th; Nicoletti, F. Transcriptional regulation of type-2 metabotropic glutamate receptors: an epigenetic path to novel treatments for chronic pain. Trends Pharmacol. Sci., 2010, 31, 153-160. http://dx.doi.org/10.1016/j.tips.2009.12.003
-
(2010)
Trends Pharmacol. Sci.
, vol.31
, pp. 153-160
-
-
Chiechio, S.1
Copani, A.2
Zammataro, M.3
Battaglia, G.4
Gereau, R.W.5
Nicoletti, F.6
-
68
-
-
84875278408
-
L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors
-
[68][68] Nasca, C.; Xenos, D.; Barone, Y.; Caruso, A.; Scaccianoce, S.; Matrisciano, F.; Battaglia, G.; Mathe, A.A.; Pittaluga, A.; Lionetto, L.; Simmaco, M.; Nicoletti, F. L-acetylcarnitine causes rapid antidepressant effects through the epigenetic induction of mGlu2 receptors. Proc. Natl. Acad. Sci. U S A., 2013, 110, 4804-4809. http://dx.doi.org/10.1073/pnas.1216100110
-
(2013)
Proc. Natl. Acad. Sci. U S A.
, vol.110
, pp. 4804-4809
-
-
Nasca, C.1
Xenos, D.2
Barone, Y.3
Caruso, A.4
Scaccianoce, S.5
Matrisciano, F.6
Battaglia, G.7
Mathe, A.A.8
Pittaluga, A.9
Lionetto, L.10
Simmaco, M.11
Nicoletti, F.12
|