DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients

Schizophrenia Research

Volumn 167, Issue 1-3, 2015, Pages 35-41

  Dong, E ^a   Ruzicka, W B ^b,c   Grayson, D R ^a   Guidotti, A ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

^b MCLEAN HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Bipolar disorder; DNMT1; Epigenetics; Glutamate decarboxylase; Methylation; Schizophrenia; TET1

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; DNA METHYLTRANSFERASE 1; PROTEIN GAD1; PROTEIN RELN; UNCLASSIFIED DRUG; 4 AMINOBUTYRIC ACID; CYTOSINE; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; DNA BINDING PROTEIN; GLUTAMATE DECARBOXYLASE; GLUTAMATE DECARBOXYLASE 1; MESSENGER RNA; MIXED FUNCTION OXIDASE; NERVE CELL ADHESION MOLECULE; NERVE PROTEIN; ONCOPROTEIN; PROTEIN BINDING; REELIN PROTEIN; SCLEROPROTEIN; SERINE PROTEINASE; TET1 PROTEIN, HUMAN;

ADULT; ARTICLE; BINDING AFFINITY; BIPOLAR DISORDER; BRAIN CORTEX; BRAIN REGION; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; CPG ISLAND; DISEASE ASSOCIATION; DNA METHYLATION; DNMT1 GENE; DOWN REGULATION; ENZYME MECHANISM; FEMALE; GABAERGIC SYSTEM; GENE; GENE EXPRESSION REGULATION; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RISK FACTOR; SCHIZOPHRENIA; TET1 GENE; UPREGULATION; AGED; ANALYSIS OF VARIANCE; BRAIN; CHROMATIN IMMUNOPRECIPITATION; DEFICIENCY; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; PROMOTER REGION; VERY ELDERLY;

AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; BIPOLAR DISORDER; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL ADHESION MOLECULES, NEURONAL; CHROMATIN IMMUNOPRECIPITATION; CYTOSINE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE; DNA METHYLATION; DNA-BINDING PROTEINS; EXTRACELLULAR MATRIX PROTEINS; FEMALE; GAMMA-AMINOBUTYRIC ACID; GLUTAMATE DECARBOXYLASE; HUMANS; MALE; MIDDLE AGED; MIXED FUNCTION OXYGENASES; NERVE TISSUE PROTEINS; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; SCHIZOPHRENIA; SERINE ENDOPEPTIDASES;

EID: 84942091930     PISSN: 09209964     EISSN: 15732509     Source Type: Journal    
DOI: 10.1016/j.schres.2014.10.030     Document Type: Article

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