L-acetylcarnitine induces analgesia by selectively upregulating mGlu2 metabotropic glutamate receptors

Molecular Pharmacology

Volumn 61, Issue 5, 2002, Pages 989-996

  Chiechio, S ^a   Caricasole, A ^b   Barletta, E ^c   Storto, M ^d   Catania, M V ^d   Copani, A ^d   Vertechy, M ^a   Nicolai, R ^d   Calvani, M ^c   Melchiorri, D ^d   Nicoletti, F ^a,d  

^a UNIVERSITY OF CATANIA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c CNR Catania ^*

^d Sigma Tau SpA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO 2 (2 CARBOXYCYCLOPROPYL) 3 (XANTHEN 9 YL)PROPIONIC ACID; GLUTAMATE 1A RECEPTOR; GLUTAMATE 2 RECEPTOR; GLUTAMATE 3 RECEPTOR; GLUTAMATE 5 RECEPTOR; LEVACECARNINE; METABOTROPIC RECEPTOR; METABOTROPIC RECEPTOR ANTAGONIST; RECEPTOR SUBTYPE; UNCLASSIFIED DRUG;

ALLODYNIA; ANALGESIA; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CEREBELLUM; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; HEAT SENSITIVITY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; LUMBAR SPINAL CORD; MALE; NERVE CELL PLASTICITY; NERVE TRACT; NEUROPATHY; NOCICEPTION; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCIATIC NERVE; SPINAL CORD DORSAL HORN; SPINAL GANGLION; TREATMENT OUTCOME;

ACETYLCARNITINE; ANALGESIA; ANIMALS; MALE; NOOTROPIC AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, METABOTROPIC GLUTAMATE; SCIATIC NERVE; TEMPERATURE; UP-REGULATION;

EID: 18344385695     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.61.5.989     Document Type: Article

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