Intracellular ATP decrease mediates NLRP3 inflammasome activation upon nigericin and crystal stimulation

Journal of Immunology

Volumn 195, Issue 12, 2015, Pages 5718-5724

  Nomura, Johji ^a,b   So, Alexander ^b   Tamura, Mizuho ^a   Busso, Nathalie ^b  

^a TEIJIN PHARMA LIMITED   (Japan)

^b LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCIUM ION; CRYOPYRIN; DEOXYGLUCOSE; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; NIGERICIN; POTASSIUM ION; URATE; LRRN3 PROTEIN, MOUSE; NERVE PROTEIN; URIC ACID;

ANIMAL CELL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; FEEDBACK SYSTEM; GLYCOLYSIS; HUMAN; HUMAN CELL; INFLAMMATION; MACROPHAGE ACTIVATION; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; ANIMAL; C57BL MOUSE; CELL CULTURE; IMMUNOLOGY; INTRACELLULAR SPACE; MACROPHAGE; METABOLISM;

ADENOSINE TRIPHOSPHATE; ANIMALS; CASPASE 1; CELLS, CULTURED; DEOXYGLUCOSE; HUMANS; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-1BETA; INTRACELLULAR SPACE; MACROPHAGES; MICE, INBRED C57BL; NERVE TISSUE PROTEINS; NIGERICIN; URIC ACID;

EID: 84958280606     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402512     Document Type: Article

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