메뉴 건너뛰기




Volumn 599, Issue , 2016, Pages 3-12

Butyric acid increases transepithelial transport of ferulic acid through upregulation of the monocarboxylate transporters SLC16A1 (MCT1) and SLC16A3 (MCT4)

Author keywords

Butyric acid; Caco 2; Ferulic acid; Intestine; MCT; Short chain fatty acids

Indexed keywords

3,4 DIMETHOXYCINNAMIC ACID; BUTYRIC ACID; DIHYDROFERULIC ACID; FERULIC ACID; FERULIC ACID GLUCURONIDE; FERULIC ACID SULFATE; MESSENGER RNA; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER 4; PHENOL DERIVATIVE; UNCLASSIFIED DRUG; COTRANSPORTER; COUMARIC ACID; MONOCARBOXYLATE TRANSPORT PROTEIN 1; MONOCARBOXYLATE TRANSPORTER; MUSCLE PROTEIN; SLC16A4 PROTEIN, HUMAN;

EID: 84957692408     PISSN: 00039861     EISSN: 10960384     Source Type: Journal    
DOI: 10.1016/j.abb.2016.01.018     Document Type: Article
Times cited : (43)

References (50)
  • 1
    • 84865444309 scopus 로고    scopus 로고
    • Formation of phenolic microbial metabolites and short-chain fatty acids from rye, wheat, and oat bran and their fractions in the metabolical in vitro colon model
    • E. Nordlund, A.-M. Aura, I. Mattila, T. Kosso, X. Rouau, and K. Poutanen Formation of phenolic microbial metabolites and short-chain fatty acids from rye, wheat, and oat bran and their fractions in the metabolical in vitro colon model J. Agric. Food Chem. 60 2012 8134 8145
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 8134-8145
    • Nordlund, E.1    Aura, A.-M.2    Mattila, I.3    Kosso, T.4    Rouau, X.5    Poutanen, K.6
  • 2
    • 84894160915 scopus 로고    scopus 로고
    • Estimation and interpretation of fermentation in the gut: Coupling results from a 24 h batch in vitro system with fecal measurements from a human intervention feeding study using fructo-oligosaccharides, inulin, gum acacia, and pea fiber
    • K.J. Koecher, J.A. Noack, D.A. Timm, A.S. Klosterbuer, W. Thomas, and J.L. Slavin Estimation and interpretation of fermentation in the gut: coupling results from a 24 h batch in vitro system with fecal measurements from a human intervention feeding study using fructo-oligosaccharides, inulin, gum acacia, and pea fiber J. Agric. Food Chem. 62 2014 1332 1337
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 1332-1337
    • Koecher, K.J.1    Noack, J.A.2    Timm, D.A.3    Klosterbuer, A.S.4    Thomas, W.5    Slavin, J.L.6
  • 4
    • 84863697983 scopus 로고    scopus 로고
    • Inhibition of butyrate uptake by the primary bile salt chenodeoxycholic acid in intestinal epithelial cells
    • P. Goncalves, T. Catarino, I. Gregorio, and F. Martel Inhibition of butyrate uptake by the primary bile salt chenodeoxycholic acid in intestinal epithelial cells J. Cell. Biochem. 113 2012 2937 2947
    • (2012) J. Cell. Biochem. , vol.113 , pp. 2937-2947
    • Goncalves, P.1    Catarino, T.2    Gregorio, I.3    Martel, F.4
  • 5
    • 1242340302 scopus 로고    scopus 로고
    • The SLC16 gene family - From monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond
    • A.P. Halestrap, and D. Meredith The SLC16 gene family - from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond Pflüg. Arch. Eur. J. Physiol. 447 2004 619 628
    • (2004) Pflüg. Arch. Eur. J. Physiol. , vol.447 , pp. 619-628
    • Halestrap, A.P.1    Meredith, D.2
  • 6
    • 33645969256 scopus 로고    scopus 로고
    • SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter
    • N. Gupta, P.M. Martin, P.D. Prasad, and V. Ganapathy SLC5A8 (SMCT1)-mediated transport of butyrate forms the basis for the tumor suppressive function of the transporter Life Sci. 78 2006 2419 2425
    • (2006) Life Sci. , vol.78 , pp. 2419-2425
    • Gupta, N.1    Martin, P.M.2    Prasad, P.D.3    Ganapathy, V.4
  • 7
    • 84855444042 scopus 로고    scopus 로고
    • The monocarboxylate transporter family - Structure and functional characterization
    • A.P. Halestrap The monocarboxylate transporter family - structure and functional characterization IUBMB Life 64 2012 1 9
    • (2012) IUBMB Life , vol.64 , pp. 1-9
    • Halestrap, A.P.1
  • 8
    • 84875153197 scopus 로고    scopus 로고
    • Glucose transport families SLC5 and SLC50
    • E.M. Wright Glucose transport families SLC5 and SLC50 Mol. Asp. Med. 34 2013 183 196
    • (2013) Mol. Asp. Med. , vol.34 , pp. 183-196
    • Wright, E.M.1
  • 9
    • 0028844444 scopus 로고
    • Kinetic studies on colonocyte metabolism of short chain fatty acids and glucose in ulcerative colitis
    • M.R. Clausen, and P.B. Mortensen Kinetic studies on colonocyte metabolism of short chain fatty acids and glucose in ulcerative colitis Gut 37 1995 684 689
    • (1995) Gut , vol.37 , pp. 684-689
    • Clausen, M.R.1    Mortensen, P.B.2
  • 10
    • 0019940133 scopus 로고
    • Utilization of nutrients by isolated epithelial cells of the rat colon
    • W.E.W. Roediger Utilization of nutrients by isolated epithelial cells of the rat colon Gastroenterology 83 1982 424 429
    • (1982) Gastroenterology , vol.83 , pp. 424-429
    • Roediger, W.E.W.1
  • 12
    • 84871883810 scopus 로고    scopus 로고
    • A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate
    • K.Y.C. Fung, L. Cosgrove, T. Lockett, R. Head, and D.L. Topping A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate Br. J. Nutr. 108 2012 820 831
    • (2012) Br. J. Nutr. , vol.108 , pp. 820-831
    • Fung, K.Y.C.1    Cosgrove, L.2    Lockett, T.3    Head, R.4    Topping, D.L.5
  • 13
    • 0036522023 scopus 로고    scopus 로고
    • Substrate-induced regulation of the human colonic monocarboxylate transporter, MCT1
    • M.A. Cuff, D.W. Lambert, and S.P. Shirazi-Beechey Substrate-induced regulation of the human colonic monocarboxylate transporter, MCT1 J. Physiol. Lond. 539 2002 361 371
    • (2002) J. Physiol. Lond. , vol.539 , pp. 361-371
    • Cuff, M.A.1    Lambert, D.W.2    Shirazi-Beechey, S.P.3
  • 14
    • 62449195194 scopus 로고    scopus 로고
    • Dietary pectin up-regulates monocaboxylate transporter 1 in the rat gastrointestinal tract
    • D. Kirat, K. Kondo, R. Shimada, and S. Kato Dietary pectin up-regulates monocaboxylate transporter 1 in the rat gastrointestinal tract Exp. Physiol. 94 2009 422 433
    • (2009) Exp. Physiol. , vol.94 , pp. 422-433
    • Kirat, D.1    Kondo, K.2    Shimada, R.3    Kato, S.4
  • 15
    • 38149008306 scopus 로고    scopus 로고
    • Kinetic analysis of butyrate transport in human colon adenocarcinoma cells reveals two different carrier-mediated mechanisms
    • E. Lecona, N. Olmo, J. Turnay, A. Santiago-Gomez, I.L. De Silanes, M. Gorospe, and et al. Kinetic analysis of butyrate transport in human colon adenocarcinoma cells reveals two different carrier-mediated mechanisms Biochem. J. 409 2008 311 320
    • (2008) Biochem. J. , vol.409 , pp. 311-320
    • Lecona, E.1    Olmo, N.2    Turnay, J.3    Santiago-Gomez, A.4    De Silanes, I.L.5    Gorospe, M.6
  • 16
    • 84874710218 scopus 로고    scopus 로고
    • A diet high in resistant starch modulates microbiota composition, SCFA concentrations, and gene expression in pig intestine
    • D. Haenen, J. Zhang, C.S. da Silva, G. Bosch, I.M. van der Meer, J. van Arkel, and et al. A diet high in resistant starch modulates microbiota composition, SCFA concentrations, and gene expression in pig intestine J. Nutr. 143 2013 274 283
    • (2013) J. Nutr. , vol.143 , pp. 274-283
    • Haenen, D.1    Zhang, J.2    Da Silva, C.S.3    Bosch, G.4    Van Der Meer, I.M.5    Van Arkel, J.6
  • 18
    • 33750181267 scopus 로고    scopus 로고
    • Regional levels of drug transporters along the human intestinal tract: Co-expression of ABC and SLC transporters and comparison with caco-2 cells
    • G. Englund, F. Rorsman, A. Ronnblom, U. Karlbom, L. Lazorova, J. Grasjo, and et al. Regional levels of drug transporters along the human intestinal tract: co-expression of ABC and SLC transporters and comparison with caco-2 cells Eur. J. Pharm. Sci. 29 2006 269 277
    • (2006) Eur. J. Pharm. Sci. , vol.29 , pp. 269-277
    • Englund, G.1    Rorsman, F.2    Ronnblom, A.3    Karlbom, U.4    Lazorova, L.5    Grasjo, J.6
  • 19
    • 71249103087 scopus 로고    scopus 로고
    • Cell-cell and intracellular lactate shuttles
    • G.A. Brooks Cell-cell and intracellular lactate shuttles J. Physiol. Lond. 587 2009 5591 5600
    • (2009) J. Physiol. Lond. , vol.587 , pp. 5591-5600
    • Brooks, G.A.1
  • 20
    • 84924171994 scopus 로고    scopus 로고
    • Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites
    • F. Dengler, R. Rackwitz, F. Benesch, H. Pfannkuche, and G. Gabel Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites J. Anim. Physiol. Anim. Nutr. 99 2014 379 390
    • (2014) J. Anim. Physiol. Anim. Nutr. , vol.99 , pp. 379-390
    • Dengler, F.1    Rackwitz, R.2    Benesch, F.3    Pfannkuche, H.4    Gabel, G.5
  • 21
    • 84868548497 scopus 로고    scopus 로고
    • Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids
    • H.R. El-Seedi, A.M.A. El-Said, S.A.M. Khalifa, U. Goransson, L. Bohlin, A.-K. Borg-Karlson, and et al. Biosynthesis, natural sources, dietary intake, pharmacokinetic properties, and biological activities of hydroxycinnamic acids J. Agric. Food Chem. 60 2012 10877 10895
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 10877-10895
    • El-Seedi, H.R.1    El-Said, A.M.A.2    Khalifa, S.A.M.3    Goransson, U.4    Bohlin, L.5    Borg-Karlson, A.-K.6
  • 22
    • 35448966215 scopus 로고    scopus 로고
    • Whole grain phytochemicals and health
    • R.H. Liu Whole grain phytochemicals and health J. Cereal Sci. 46 2007 207 219
    • (2007) J. Cereal Sci. , vol.46 , pp. 207-219
    • Liu, R.H.1
  • 23
    • 73549112182 scopus 로고    scopus 로고
    • Antioxidant and anti-inflammatory capacity of bioaccessible compounds from wheat fractions after gastrointestinal digestion
    • N.M. Anson, R. Havenaar, A. Bast, and G.R.M.M. Haenen Antioxidant and anti-inflammatory capacity of bioaccessible compounds from wheat fractions after gastrointestinal digestion J. Cereal Sci. 51 2010 110 114
    • (2010) J. Cereal Sci. , vol.51 , pp. 110-114
    • Anson, N.M.1    Havenaar, R.2    Bast, A.3    Haenen, G.R.M.M.4
  • 24
    • 84862078426 scopus 로고    scopus 로고
    • Wheat aleurone: Separation, composition, health aspects, and potential food use
    • F. Brouns, Y. Hemery, R. Price, and N.M. Anson Wheat aleurone: separation, composition, health aspects, and potential food use Crit. Rev. Food Sci. Nutr. 52 2012 553 568
    • (2012) Crit. Rev. Food Sci. Nutr. , vol.52 , pp. 553-568
    • Brouns, F.1    Hemery, Y.2    Price, R.3    Anson, N.M.4
  • 26
    • 0035181636 scopus 로고    scopus 로고
    • Esterase activity able to hydrolyze dietary antioxidant hydroxycinnamates is distributed along the intestine of mammals
    • M.F. Andreasen, P.A. Kroon, G. Williamson, and M.T. Garcia-Conesa Esterase activity able to hydrolyze dietary antioxidant hydroxycinnamates is distributed along the intestine of mammals J. Agric. Food Chem. 49 2001 5679 5684
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 5679-5684
    • Andreasen, M.F.1    Kroon, P.A.2    Williamson, G.3    Garcia-Conesa, M.T.4
  • 28
    • 37549062630 scopus 로고    scopus 로고
    • Transport and metabolism of ferulic acid through the colonic epithelium
    • L. Poquet, M.N. Clifford, and G. Williamson Transport and metabolism of ferulic acid through the colonic epithelium Drug Metab. Dispos. 36 2008 190 197
    • (2008) Drug Metab. Dispos. , vol.36 , pp. 190-197
    • Poquet, L.1    Clifford, M.N.2    Williamson, G.3
  • 29
    • 0041318875 scopus 로고    scopus 로고
    • Transepithelial transport of ferulic acid by monocarboxylic acid transporter in caco-2 cell monolayers
    • Y. Konishi, and M. Shimizu Transepithelial transport of ferulic acid by monocarboxylic acid transporter in caco-2 cell monolayers Biosci. Biotechnol. Biochem. 67 2003 856 862
    • (2003) Biosci. Biotechnol. Biochem. , vol.67 , pp. 856-862
    • Konishi, Y.1    Shimizu, M.2
  • 30
    • 79956081851 scopus 로고    scopus 로고
    • Characterization of hydroxycinnamic acid glucuronide and sulfate conjugates by HPLC-DAD-MS2: Enhancing chromatographic quantification and application in caco-2 cell metabolism
    • T. Farrell, L. Poquet, F. Dionisi, D. Barron, and G. Williamson Characterization of hydroxycinnamic acid glucuronide and sulfate conjugates by HPLC-DAD-MS2: enhancing chromatographic quantification and application in caco-2 cell metabolism J. Pharm. Biomed. Anal. 55 2011 1245 1254
    • (2011) J. Pharm. Biomed. Anal. , vol.55 , pp. 1245-1254
    • Farrell, T.1    Poquet, L.2    Dionisi, F.3    Barron, D.4    Williamson, G.5
  • 32
    • 76749149579 scopus 로고    scopus 로고
    • Monocarboxylate transporter-mediated transport of gamma-hydroxybutyric acid in human intestinal caco-2 cells
    • W.K. Lam, M.A. Felmlee, and M.E. Morris Monocarboxylate transporter-mediated transport of gamma-hydroxybutyric acid in human intestinal caco-2 cells Drug Metab. Dispos. 38 2010 441 447
    • (2010) Drug Metab. Dispos. , vol.38 , pp. 441-447
    • Lam, W.K.1    Felmlee, M.A.2    Morris, M.E.3
  • 33
    • 84863397848 scopus 로고    scopus 로고
    • The monocarboxylate transporter family - Role and regulation
    • A.P. Halestrap, and M.C. Wilson The monocarboxylate transporter family - role and regulation IUMB Life 64 2012 109 119
    • (2012) IUMB Life , vol.64 , pp. 109-119
    • Halestrap, A.P.1    Wilson, M.C.2
  • 34
    • 19444382806 scopus 로고    scopus 로고
    • PH-Dependent passive and active transport of acidic drugs across caco-2 cell monolayers
    • S. Neuhoff, A.L. Ungell, I. Zamora, and P. Artursson pH-Dependent passive and active transport of acidic drugs across caco-2 cell monolayers Eur. J. Pharm. Sci. 25 2005 211 220
    • (2005) Eur. J. Pharm. Sci. , vol.25 , pp. 211-220
    • Neuhoff, S.1    Ungell, A.L.2    Zamora, I.3    Artursson, P.4
  • 35
    • 72249102219 scopus 로고    scopus 로고
    • Mechanisms underlying modulation of monocarboxylate transporter 1 (MCT1) by somatostatin in human intestinal epithelial cells
    • S. Saksena, S. Theegala, N. Bansal, R.K. Gill, S. Tyagi, W.A. Alrefai, and et al. Mechanisms underlying modulation of monocarboxylate transporter 1 (MCT1) by somatostatin in human intestinal epithelial cells Am. J. Physiol. Gastrointest. Liver Physiol. 297 2009 G878 G885
    • (2009) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.297 , pp. G878-G885
    • Saksena, S.1    Theegala, S.2    Bansal, N.3    Gill, R.K.4    Tyagi, S.5    Alrefai, W.A.6
  • 36
    • 33751074139 scopus 로고    scopus 로고
    • Cellular expression of monocarboxylate transporters (MCT) in the digestive tract of the mouse, rat, and humans, with special reference to slc5a8
    • T. Iwanaga, K. Takebe, I. Kato, S.-I. Karaki, and A. Kuwahara Cellular expression of monocarboxylate transporters (MCT) in the digestive tract of the mouse, rat, and humans, with special reference to slc5a8 Biomed. Res. 27 2006 243 254
    • (2006) Biomed. Res. , vol.27 , pp. 243-254
    • Iwanaga, T.1    Takebe, K.2    Kato, I.3    Karaki, S.-I.4    Kuwahara, A.5
  • 37
    • 43249096934 scopus 로고    scopus 로고
    • Expression of the monocarboxylate transporter 1 (MCT1) in cells of the porcine intestine
    • H. Welter, and R. Claus Expression of the monocarboxylate transporter 1 (MCT1) in cells of the porcine intestine Cell Biol. Int. 32 2008 638 645
    • (2008) Cell Biol. Int. , vol.32 , pp. 638-645
    • Welter, H.1    Claus, R.2
  • 38
    • 0028909335 scopus 로고
    • CDNA cloning of MCT2, a 2nd monocarboxylate transporter expressed in different cells than MCT1
    • C.K. Garcia, M.S. Brown, R.K. Pathak, and J.L. Goldstein cDNA cloning of MCT2, a 2nd monocarboxylate transporter expressed in different cells than MCT1 J. Biol. Chem. 270 1995 1843 1849
    • (1995) J. Biol. Chem. , vol.270 , pp. 1843-1849
    • Garcia, C.K.1    Brown, M.S.2    Pathak, R.K.3    Goldstein, J.L.4
  • 39
    • 33747624390 scopus 로고    scopus 로고
    • Monocarboxylate transporter 1 (MCT1) mediates transport of short-chain fatty acids in bovine caecum
    • D. Kirat, and S. Kato Monocarboxylate transporter 1 (MCT1) mediates transport of short-chain fatty acids in bovine caecum Exp. Physiol. 91 2006 835 844
    • (2006) Exp. Physiol. , vol.91 , pp. 835-844
    • Kirat, D.1    Kato, S.2
  • 40
    • 33847691097 scopus 로고    scopus 로고
    • Expression, cellular localization, and functional role of monocarboxylate transporter 4 (MCT4) in the gastrointestinal tract of ruminants
    • D. Kirat, Y. Matsuda, N. Yamashiki, H. Hayashi, and S. Kato Expression, cellular localization, and functional role of monocarboxylate transporter 4 (MCT4) in the gastrointestinal tract of ruminants Gene 391 2007 140 149
    • (2007) Gene , vol.391 , pp. 140-149
    • Kirat, D.1    Matsuda, Y.2    Yamashiki, N.3    Hayashi, H.4    Kato, S.5
  • 41
    • 22844442936 scopus 로고    scopus 로고
    • Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4- The ancillary protein for the insensitive MCT2 is embigin (gp70)
    • M.C. Wilson, D. Meredith, J.E.M. Fox, C. Manoharan, A.J. Davies, and A.P. Halestrap Basigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4-the ancillary protein for the insensitive MCT2 is embigin (gp70) J. Biol. Chem. 280 2005 27213 27221
    • (2005) J. Biol. Chem. , vol.280 , pp. 27213-27221
    • Wilson, M.C.1    Meredith, D.2    Fox, J.E.M.3    Manoharan, C.4    Davies, A.J.5    Halestrap, A.P.6
  • 42
    • 0034254638 scopus 로고    scopus 로고
    • CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression
    • P. Kirk, M.C. Wilson, C. Heddle, M.H. Brown, A.N. Barclay, and A.P. Halestrap CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression EMBO J. 19 2000 3896 3904
    • (2000) EMBO J. , vol.19 , pp. 3896-3904
    • Kirk, P.1    Wilson, M.C.2    Heddle, C.3    Brown, M.H.4    Barclay, A.N.5    Halestrap, A.P.6
  • 43
    • 79952778708 scopus 로고    scopus 로고
    • Basolateral sorting signals regulating tissue-specific polarity of heteromeric monocarboxylate transporters in epithelia
    • J.J. Castorino, S. Deborde, A. Deora, R. Schreiner, S.M. Gallagher-Colombo, E. Rodriguez-Boulan, and et al. Basolateral sorting signals regulating tissue-specific polarity of heteromeric monocarboxylate transporters in epithelia Traffic 12 2011 483 498
    • (2011) Traffic , vol.12 , pp. 483-498
    • Castorino, J.J.1    Deborde, S.2    Deora, A.3    Schreiner, R.4    Gallagher-Colombo, S.M.5    Rodriguez-Boulan, E.6
  • 44
    • 28044456306 scopus 로고    scopus 로고
    • Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia
    • A.A. Deora, N. Philp, J. Hu, D. Bok, and E. Rodriguez-Boulan Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epithelia Proc. Natl. Acad. Sci. U. S. A. 102 2005 16245 16250
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 16245-16250
    • Deora, A.A.1    Philp, N.2    Hu, J.3    Bok, D.4    Rodriguez-Boulan, E.5
  • 45
    • 34249293335 scopus 로고    scopus 로고
    • Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231
    • S.M. Gallagher, J.J. Castorino, D. Wang, and N.J. Philp Monocarboxylate transporter 4 regulates maturation and trafficking of CD147 to the plasma membrane in the metastatic breast cancer cell line MDA-MB-231 Cancer Res. 67 2007 4182 4189
    • (2007) Cancer Res. , vol.67 , pp. 4182-4189
    • Gallagher, S.M.1    Castorino, J.J.2    Wang, D.3    Philp, N.J.4
  • 46
    • 0028964728 scopus 로고
    • A Na+-dependent mechanism is involved in mucosal uptake of cinnamic acid across the jejunal brush border in rats
    • S. Wolffram, T. Weber, B. Grenacher, and E. Scharrer A Na+-dependent mechanism is involved in mucosal uptake of cinnamic acid across the jejunal brush border in rats J. Nutr. 1995 1300 1308
    • (1995) J. Nutr. , pp. 1300-1308
    • Wolffram, S.1    Weber, T.2    Grenacher, B.3    Scharrer, E.4
  • 47
    • 56149087140 scopus 로고    scopus 로고
    • Comparison of drug transporter gene expression and functionality in caco-2 cells from 10 different laboratories
    • R. Hayeshi, C. Hilgendorf, P. Artursson, P. Augustijns, B. Brodin, P. Dehertogh, and et al. Comparison of drug transporter gene expression and functionality in caco-2 cells from 10 different laboratories Eur. J. Pharm. Sci. 35 2008 383 396
    • (2008) Eur. J. Pharm. Sci. , vol.35 , pp. 383-396
    • Hayeshi, R.1    Hilgendorf, C.2    Artursson, P.3    Augustijns, P.4    Brodin, B.5    Dehertogh, P.6
  • 48
    • 36348992468 scopus 로고    scopus 로고
    • Analysis of drug transporter expression in human intestinal caco-2 cells by real-time PCR
    • N. Maubon, M. Le Vee, L. Fossati, M. Audry, E. Le Ferrec, S. Bolze, and et al. Analysis of drug transporter expression in human intestinal caco-2 cells by real-time PCR Fundam. Clin. Pharmacol. 21 2007 659 663
    • (2007) Fundam. Clin. Pharmacol. , vol.21 , pp. 659-663
    • Maubon, N.1    Le Vee, M.2    Fossati, L.3    Audry, M.4    Le Ferrec, E.5    Bolze, S.6
  • 49
    • 0038153876 scopus 로고    scopus 로고
    • SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers
    • H. Li, L. Myeroff, D. Smiraglia, M.F. Romero, T.P. Pretlow, L. Kasturi, and et al. SLC5A8, a sodium transporter, is a tumor suppressor gene silenced by methylation in human colon aberrant crypt foci and cancers Proc. Natl. Acad. Sci. U. S. A. 100 2003 8412 8417
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 8412-8417
    • Li, H.1    Myeroff, L.2    Smiraglia, D.3    Romero, M.F.4    Pretlow, T.P.5    Kasturi, L.6
  • 50


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.