Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories

European Journal of Pharmaceutical Sciences

Volumn 35, Issue 5, 2008, Pages 383-396

  Hayeshi, Rose ^a   Hilgendorf, Constanze ^a   Artursson, Per ^b   Augustijns, Patrick ^c   Brodin, Birger ^d   Dehertogh, Pascale ^e   Fisher, Karen ^f   Fossati, Lina ^g   Hovenkamp, Egbert ^h   Korjamo, Timo ⁱ   Masungi, Chantal ^e   Maubon, Nathalie ^g   Mols, Raf ^c   Müllertz, Anette ^d   Mönkkönen, Jukka ⁱ   O'Driscoll, Caitriona ^f   Oppers Tiemissen, H M ^j   Ragnarsson, Eva G E ^b   Rooseboom, Martijn ^j   Ungell, Anna Lena ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c DEPARTMENT OF PHARMACEUTICAL AND PHARMACOLOGICAL SCIENCES   (Belgium)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

^e TIBOTEC BVBA   (Belgium)

^f UNIVERSITY COLLEGE CORK   (Ireland)

^g Laboratoires Fournier SA   (France)

^h UNILEVER RESEARCH VLAARDINGEN   (Netherlands)

ⁱ UNIVERSITY OF EASTERN FINLAND   (Finland)

^j Organon ^*  (Netherlands)

more..

Author keywords

ABC transport; Active transport; Caco 2 cells; Drug transport protein expression; Drug transport protein function; SLC transport

Indexed keywords

ABC TRANSPORTER; ATENOLOL; DRUG METABOLIZING ENZYME; GLUCOSE TRANSPORTER 3; GLUCOSE TRANSPORTER 5; GLUTATHIONE TRANSFERASE A1; METOPROLOL; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; ORGANIC ANION TRANSPORTER; PEPTIDE TRANSPORTER 1; TALINOLOL;

ACTIVE TRANSPORT; ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; CORRELATION ANALYSIS; DRUG PENETRATION; DRUG TRANSPORT; GENE EXPRESSION; HUMAN; HUMAN CELL; PASSIVE TRANSPORT; PRIORITY JOURNAL; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION;

CACO-2 CELLS; CARRIER PROTEINS; DATA INTERPRETATION, STATISTICAL; DNA, COMPLEMENTARY; GENE EXPRESSION; GENETIC MARKERS; HUMANS; LABORATORIES; PERMEABILITY; PHARMACEUTICAL PREPARATIONS; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 56149087140     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejps.2008.08.004     Document Type: Article

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