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Volumn 21, Issue 42, 2015, Pages 6055-6069

Modern drug delivery systems for targeting the posterior segment of the Eye

Author keywords

Drug delivery; Hydrogels; Implants; Intravitreal; Liposomes; Micro and nanoparticles; Posterior segment of the eye; Sustained release

Indexed keywords

LIPOSOME; NANOCARRIER; NANOPARTICLE; DRUG; DRUG IMPLANT; HYDROGEL; MICROSPHERE;

EID: 84957544822     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/1381612821666151027151847     Document Type: Article
Times cited : (19)

References (131)
  • 1
    • 84855599366 scopus 로고    scopus 로고
    • Sustained release intraocular drug delivery devices for treatment of uveitis
    • Haghjou N, Soheilian M, Abdekhodaie MJ. Sustained release intraocular drug delivery devices for treatment of uveitis. J Ophthalmic Vis Res 2011; 6(4): 317-29.
    • (2011) J Ophthalmic Vis Res , vol.6 , Issue.4 , pp. 317-329
    • Haghjou, N.1    Soheilian, M.2    Abdekhodaie, M.J.3
  • 2
    • 79951991772 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye through hydrogel contact lenses
    • Schultz C, Breaux J, Schentag J, Morck D. Drug delivery to the posterior segment of the eye through hydrogel contact lenses. Clin Exp Optom 2011; 94(2): 212-8.
    • (2011) Clin Exp Optom , vol.94 , Issue.2 , pp. 212-218
    • Schultz, C.1    Breaux, J.2    Schentag, J.3    Morck, D.4
  • 3
    • 53549113112 scopus 로고    scopus 로고
    • Novel Drug Delivery Systems for Posterior Segment Ocular Diseas
    • Edited by: J. Tombran-Tink and CJ Barnstable © Humana Press Inc., Totowa, NJ
    • Sheardown H, Mark Saltzman W. Novel Drug Delivery Systems for Posterior Segment Ocular Diseas, In Ocular Angiogenesis: Diseases, Mechanisms, and Therapeutics. Edited by: J. Tombran-Tink and CJ Barnstable © Humana Press Inc., Totowa, NJ 2006; 393-408.
    • (2006) Ocular Angiogenesis: Diseases, Mechanisms, and Therapeutics , pp. 393-408
    • Sheardown, H.1    Mark Saltzman, W.2
  • 4
    • 79952236067 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye for pharmacologic therapy
    • Shah SS, Lori Vidal Denham, Jasmine R, et al. Drug delivery to the posterior segment of the eye for pharmacologic therapy. Expert Rev Ophthalmol 2010; 1; 5(1): 75-93.
    • (2010) Expert Rev Ophthalmol , vol.5 , Issue.1 , pp. 75-93
    • Shah, S.S.1    Denham, L.V.2    Jasmine, R.3
  • 5
    • 77953173751 scopus 로고    scopus 로고
    • New techniques for drug delivery to the posterior eye segment
    • Eljarrat-Binstock E, Pe’er J, Domb AJ. New techniques for drug delivery to the posterior eye segment. Pharm Res 2010; 27(4): 530-43.
    • (2010) Pharm Res , vol.27 , Issue.4 , pp. 530-543
    • Eljarrat-Binstock, E.1    Pe’Er, J.2    Domb, A.J.3
  • 8
    • 84908269334 scopus 로고    scopus 로고
    • Nanotherapy for posterior eye diseases
    • Kaur IP, Kakkar S. Nanotherapy for posterior eye diseases. J Control Release 2014; 193: 100-12.
    • (2014) J Control Release , vol.193 , pp. 100-112
    • Kaur, I.P.1    Kakkar, S.2
  • 9
    • 84940912498 scopus 로고    scopus 로고
    • Drug delivery to the posterior segment of the eye: Challenges and opportunities
    • Thrimawithana TR, Young S, Bunt CR, Greend C, Alany RG. Drug delivery to the posterior segment of the eye: challenges and opportunities. Drug Deliv Lett 2011, 1(1): 40-4
    • (2011) Drug Deliv Lett , vol.1 , Issue.1 , pp. 40-44
    • Thrimawithana, T.R.1    Young, S.2    Bunt, C.R.3    Greend, C.4    Alany, R.G.5
  • 13
    • 84957572776 scopus 로고    scopus 로고
    • Ocular pharmacokinetic, drug bioavailability and intraocular drug delivery systems
    • Nguyen QD, Rodrigues EB, Farah ME, Mieler WF (eds.)
    • Herrero-Vanrell R, Cardillo JA. Ocular pharmacokinetic, drug bioavailability and intraocular drug delivery systems. In: Nguyen QD, Rodrigues EB, Farah ME, Mieler WF (eds.). China: Saunders Elsevier 2010; 60-66.
    • (2010) China: Saunders Elsevier , pp. 60-66
    • Herrero-Vanrell, R.1    Cardillo, J.A.2
  • 14
    • 0842309564 scopus 로고    scopus 로고
    • The blood-retinal barrier system. Basic concepts and clinical evaluation
    • Cunha-Vaz JG. The blood-retinal barrier system. Basic concepts and clinical evaluation. Exp Eye Res 2004; 78(3): 715-21.
    • (2004) Exp Eye Res , vol.78 , Issue.3 , pp. 715-721
    • Cunha-Vaz, J.G.1
  • 15
    • 39149121847 scopus 로고    scopus 로고
    • Current and future ophthalmic drug delivery systems. A shift to the posterior segment
    • Del Amo EM, Urtti A. Current and future ophthalmic drug delivery systems. A shift to the posterior segment. Drug Discov Today 2008; 13: 135-143.
    • (2008) Drug Discov Today , vol.13 , pp. 135-143
    • Del Amo, E.M.1    Urtti, A.2
  • 16
    • 79955022978 scopus 로고    scopus 로고
    • Ophthalmic drug delivery systems for the treatment of retinal diseases: Basic research to clinical applications
    • Edelhauser HF, Rowe-Rendleman CL, Robinson MR, et al. Ophthalmic drug delivery systems for the treatment of retinal diseases: basic research to clinical applications. Invest Ophthalmol Vis Sci 2010; 51: 5403-20.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , pp. 5403-5420
    • Edelhauser, H.F.1    Rowe-Rendleman, C.L.2    Robinson, M.R.3
  • 18
    • 33751172725 scopus 로고    scopus 로고
    • Drug transport in corneal epithelium and blood-retina barrier: Emerging role of transporters in ocular pharmacokinetics
    • Mannerma E, Vellonen KS, Urtti A. Drug transport in corneal epithelium and blood-retina barrier: emerging role of transporters in ocular pharmacokinetics. Adv Drug Deliv Rev 2006; 58: 1136-63.
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1136-1163
    • Mannerma, E.1    Vellonen, K.S.2    Urtti, A.3
  • 19
    • 82255172039 scopus 로고    scopus 로고
    • Topical Drug Delivery for Posterior Segment Disease Novel formulations offer possibilities for efficacious therapies through topical routes
    • Kiernan DF, Lim JI. Topical Drug Delivery for Posterior Segment Disease Novel formulations offer possibilities for efficacious therapies through topical routes. Retina Today 2010; 48: 48-54.
    • (2010) Retina Today , vol.48 , pp. 48-54
    • Kiernan, D.F.1    Lim, J.I.2
  • 20
    • 34447313299 scopus 로고    scopus 로고
    • Topical and systemic absorption in delivery of dexamethasone to the anterior and posterior segments of the eye
    • Sigurdsson HH, Konrásdóttir F, Loftsson T, Stefánsson E. Topical and systemic absorption in delivery of dexamethasone to the anterior and posterior segments of the eye. Acta Ophthalmol Scand 2007; 85: 598-602.
    • (2007) Acta Ophthalmol Scand , vol.85 , pp. 598-602
    • Sigurdsson, H.H.1    Konrásdóttir, F.2    Loftsson, T.3    Stefánsson, E.4
  • 21
    • 49549110073 scopus 로고    scopus 로고
    • Inhibitors of vascular endothelial growth factor (VEGF) in the management of neovascular agerelated macular degeneration: A review of current practice
    • Van Wijngaarden P, Qureshi SH. Inhibitors of vascular endothelial growth factor (VEGF) in the management of neovascular agerelated macular degeneration: a review of current practice. Clin Exp Optom 2008; 91: 427-43.
    • (2008) Clin Exp Optom , vol.91 , pp. 427-443
    • Van Wijngaarden, P.1    Qureshi, S.H.2
  • 22
    • 64849111444 scopus 로고    scopus 로고
    • Intravitreal bevacizumab (Avastin®) for macular oedema secondary to retinal vein occlusion: 12-month results of a prospective clinical trial
    • Prager F, Michels S, Kriechbaum K, et al. Intravitreal bevacizumab (Avastin®) for macular oedema secondary to retinal vein occlusion: 12-month results of a prospective clinical trial. Br J Ophthalmol 2009; 93: 452-6.
    • (2009) Br J Ophthalmol , vol.93 , pp. 452-456
    • Prager, F.1    Michels, S.2    Kriechbaum, K.3
  • 23
    • 66349109049 scopus 로고    scopus 로고
    • Preparation, characterization, and in vivo evaluation of nanoliposomes encapsulated bevacizumab (Avastin) for intravitreal administration
    • Abrishami M, Ganavati SZ, Soroush D, Rouhbakhsh M, Jaafari MR, Malaekeh-Nikouei B. Preparation, characterization, and in vivo evaluation of nanoliposomes encapsulated bevacizumab (avastin) for intravitreal administration. Retina Today 2009; 29: 699-703.
    • (2009) Retina Today , vol.29 , pp. 699-703
    • Abrishami, M.1    Ganavati, S.Z.2    Soroush, D.3    Rouhbakhsh, M.4    Jaafari, M.R.5    Malaekeh-Nikouei, B.6
  • 24
    • 84908285905 scopus 로고    scopus 로고
    • Intravitreal steroids for the treatment of retinal diseases
    • Sarao V, Veritti D, Boscia F, Lanzetta P. Intravitreal steroids for the treatment of retinal diseases. Sci World J 2014; 14: 1-14.
    • (2014) Sci World J , vol.14 , pp. 1-14
    • Sarao, V.1    Veritti, D.2    Boscia, F.3    Lanzetta, P.4
  • 25
    • 59849104241 scopus 로고    scopus 로고
    • Molecular pathology of age-related macular degeneration
    • Ding X, Patel M, Chan CC. Molecular pathology of age-related macular degeneration. Prog Retin Eye Res 2009; 28(1): 1-18
    • (2009) Prog Retin Eye Res , vol.28 , Issue.1 , pp. 1-18
    • Ding, X.1    Patel, M.2    Chan, C.C.3
  • 26
    • 52949137851 scopus 로고    scopus 로고
    • Age-related macular degeneration: A target for nanotechnology derived medicines
    • Birch DG, Liang FQ. Age-related macular degeneration: a target for nanotechnology derived medicines. Int J Nanomed 2007; 2(1): 65-77.
    • (2007) Int J Nanomed , vol.2 , Issue.1 , pp. 65-77
    • Birch, D.G.1    Liang, F.Q.2
  • 27
    • 33749445317 scopus 로고    scopus 로고
    • Ranibizumab for neovascular age-related macular degeneration
    • Rosenfeld PJ, Brown DM, Heier JS, et al. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med 2006; 355: 1419-31.
    • (2006) N Engl J Med , vol.355 , pp. 1419-1431
    • Rosenfeld, P.J.1    Brown, D.M.2    Heier, J.S.3
  • 28
    • 11144253482 scopus 로고    scopus 로고
    • Vitreous concentrations of triamcinolone acetonide in human eyes after intravitreal or subtenon injection
    • Inoue M, Takeda K, Morita K, Yamada M, Tanigawara Y, Oguchi Y. Vitreous concentrations of triamcinolone acetonide in human eyes after intravitreal or subtenon injection. Am J Ophthalmol 2004; 138: 1046-8.
    • (2004) Am J Ophthalmol , vol.138 , pp. 1046-1048
    • Inoue, M.1    Takeda, K.2    Morita, K.3    Yamada, M.4    Tanigawara, Y.5    Oguchi, Y.6
  • 30
    • 84871552617 scopus 로고    scopus 로고
    • Novel nanomicellar formulation approaches for anterior and posterior segment ocular drug delivery
    • Cholkar K, Patel A, Vadlapudi AD, Mitra AK. Novel nanomicellar formulation approaches for anterior and posterior segment ocular drug delivery. Recent Pat Nanomed 2012; 2(2): 82-95.
    • (2012) Recent Pat Nanomed , vol.2 , Issue.2 , pp. 82-95
    • Cholkar, K.1    Patel, A.2    Vadlapudi, A.D.3    Mitra, A.K.4
  • 31
    • 84875026465 scopus 로고    scopus 로고
    • The vitreous humor as a barrier to nanoparticle distribution
    • Mains J, Wilson CG. The vitreous humor as a barrier to nanoparticle distribution. J Ocul Pharmacol Ther 2013; 29(2): 143-50.
    • (2013) J Ocul Pharmacol Ther , vol.29 , Issue.2 , pp. 143-150
    • Mains, J.1    Wilson, C.G.2
  • 32
    • 0034821034 scopus 로고    scopus 로고
    • Review: Practical issues in intravitreal drug delivery
    • Maurice D. Review: practical issues in intravitreal drug delivery. J Ocul Pharmacol Ther 2001; 17: 393-401.
    • (2001) J Ocul Pharmacol Ther , vol.17 , pp. 393-401
    • Maurice, D.1
  • 33
    • 78649529307 scopus 로고    scopus 로고
    • Barrier analysis of periocular drug delivery to the posterior segment
    • Ranta VP, Mannermaa E, Lummepuro K, et al. Barrier analysis of periocular drug delivery to the posterior segment. J Control Release 2010; 148: 42-8.
    • (2010) J Control Release , vol.148 , pp. 42-48
    • Ranta, V.P.1    Mannermaa, E.2    Lummepuro, K.3
  • 34
    • 78651245667 scopus 로고    scopus 로고
    • Suprachoroidal drug delivery to the back of the eye using hollow microneedles
    • Patel SR, Lin AS, Edelhauser HF, Prausnitz MR. Suprachoroidal drug delivery to the back of the eye using hollow microneedles. Pharm Res 2011; 28(1): 166-76.
    • (2011) Pharm Res , vol.28 , Issue.1 , pp. 166-176
    • Patel, S.R.1    Lin, A.S.2    Edelhauser, H.F.3    Prausnitz, M.R.4
  • 36
    • 33751187547 scopus 로고    scopus 로고
    • Challanges and obstacles of ocular pharmacokinetics and drug delivery
    • Urtti A. Challanges and obstacles of ocular pharmacokinetics and drug delivery, Adv Drug Deliv Rev 2006; 58(11): 1131-5.
    • (2006) Adv Drug Deliv Rev , vol.58 , Issue.11 , pp. 1131-1135
    • Urtti, A.1
  • 37
    • 33646925637 scopus 로고    scopus 로고
    • Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis-Thirty-fourweek results of a multicenter randomized clinical study
    • Jaffe GJ, Martin D, Callanan D, et al. Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis-Thirty-fourweek results of a multicenter randomized clinical study. Ophthalmology 2006; 113(6): 1020-7.
    • (2006) Ophthalmology , vol.113 , Issue.6 , pp. 1020-1027
    • Jaffe, G.J.1    Martin, D.2    Callanan, D.3
  • 38
    • 38949152259 scopus 로고    scopus 로고
    • Delivery systems for the treatment of proliferative vitreoretinopathy: Materials, devices and colloidal carriers
    • Guidetti B, Azema J, Malet-Martino M, Martino R. Delivery systems for the treatment of proliferative vitreoretinopathy: materials, devices and colloidal carriers. Curr Drug Deliv 2008; 5(1): 7-19.
    • (2008) Curr Drug Deliv , vol.5 , Issue.1 , pp. 7-19
    • Guidetti, B.1    Azema, J.2    Malet-Martino, M.3    Martino, R.4
  • 39
    • 77951282109 scopus 로고    scopus 로고
    • Review of Implantable Intravitreal Drug Delivery Technologies for the Treatment of Posterior Segment Eye. Diseases
    • Choonara YE, Pillay V, Danckwerts MP, Carmichael TR, DuToit LC. A Review of Implantable Intravitreal Drug Delivery Technologies for the Treatment of Posterior Segment Eye. Diseases. J Pharm Sci 2010; 99(5): 2219-39.
    • (2010) J Pharm Sci , vol.99 , Issue.5 , pp. 2219-2239
    • Choonara, Y.E.1    Pillay, V.2    Danckwerts, M.P.3    Carmichael, T.R.4    Dutoit, L.5
  • 40
    • 33751268869 scopus 로고    scopus 로고
    • Intraocular implants for extended drug delivery: Therapeutic applications
    • Bourges JL, Bloquela C, Thomasa A, et al. Intraocular implants for extended drug delivery: therapeutic applications. Adv Drug Deliv Rev 2006; 58: 1182-202.
    • (2006) Adv Drug Deliv Rev , vol.58 , pp. 1182-1202
    • Bourges, J.L.1    Bloquela, C.2    Thomasa, A.3
  • 41
    • 0030004075 scopus 로고    scopus 로고
    • Use of the ganciclovir implant in the treatment of recurrent cytomegalovirus retinitis
    • Marx JL, Kapusta MA, Patel Sunil S, et al. Use of the ganciclovir implant in the treatment of recurrent cytomegalovirus retinitis. Arch Ophthalmol 1996; 114: 815-20.
    • (1996) Arch Ophthalmol , vol.114 , pp. 815-820
    • Marx, J.L.1    Kapusta, M.A.2    Patel Sunil, S.3
  • 42
    • 65549117729 scopus 로고    scopus 로고
    • Intravitreal inserts of steroids to treat diabetic macular edema
    • Montero JA, Ruiz-Moreno JM. Intravitreal inserts of steroids to treat diabetic macular edema. Curr Diabetes Rev 2009; 5(1): 26-32.
    • (2009) Curr Diabetes Rev , vol.5 , Issue.1 , pp. 26-32
    • Montero, J.A.1    Ruiz-Moreno, J.M.2
  • 43
    • 62849109726 scopus 로고    scopus 로고
    • Novel drug delivery systems for retinal diseases: A review
    • Lee SS, Robinson MR. Novel drug delivery systems for retinal diseases: a review. Ophthalmic Res 2009; 41(3): 124-35.
    • (2009) Ophthalmic Res , vol.41 , Issue.3 , pp. 124-135
    • Lee, S.S.1    Robinson, M.R.2
  • 45
    • 1542267852 scopus 로고    scopus 로고
    • Bioerodable eye implant may help treat macular edema
    • Russel R. Bioerodable eye implant may help treat macular edema, Pharma Technol 2004; 28(18): 223.
    • (2004) Pharma Technol , vol.28 , Issue.18 , pp. 223
    • Russel, R.1
  • 46
    • 0037308517 scopus 로고    scopus 로고
    • Biodegradable intrascleral implant for sustained intraocular delivery of betamethasone phosphate
    • Okabe J, Kimura H, Kunou N, Okabe K, Kato A, Ogura Y. Biodegradable intrascleral implant for sustained intraocular delivery of betamethasone phosphate. Invest Ophthalmol Vis Sci 2003; 44: 740-4.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , pp. 740-744
    • Okabe, J.1    Kimura, H.2    Kunou, N.3    Okabe, K.4    Kato, A.5    Ogura, Y.6
  • 47
    • 53249147453 scopus 로고    scopus 로고
    • NT-501: An ophthalmic implant of polymer encapsulated ciliary neurotrophic factor-producing cells
    • Emerich DF, Thanos CG. NT-501: an ophthalmic implant of polymer encapsulated ciliary neurotrophic factor-producing cells. Curr Opin Mol Ther 2008; 10(5): 506-15.
    • (2008) Curr Opin Mol Ther , vol.10 , Issue.5 , pp. 506-515
    • Emerich, D.F.1    Thanos, C.G.2
  • 48
    • 3042763334 scopus 로고    scopus 로고
    • Ocular pharmacokineticsof fluocinolone acetonide after Retisert intravitreal implantation in rabbits over a 1-year period
    • Driot JY, Novack GD, Rittenhouse KD, Milazzo C, Pearson PA. Ocular pharmacokineticsof fluocinolone acetonide after Retisert intravitreal implantation in rabbits over a 1-year period. J Ocul Pharmacol Ther 2004; 20(3): 269-75.
    • (2004) J Ocul Pharmacol Ther , vol.20 , Issue.3 , pp. 269-275
    • Driot, J.Y.1    Novack, G.D.2    Rittenhouse, K.D.3    Milazzo, C.4    Pearson, P.A.5
  • 50
    • 28444460727 scopus 로고    scopus 로고
    • Intraocular sustained drug delivery using implantable polymeric devices
    • Yasukawa T, Ogura Y, Sakurai E, Tabata Y, Kimura H. Intraocular sustained drug delivery using implantable polymeric devices. Adv Drug Deliv Rev 2005; 57(14): 2033-46.
    • (2005) Adv Drug Deliv Rev , vol.57 , Issue.14 , pp. 2033-2046
    • Yasukawa, T.1    Ogura, Y.2    Sakurai, E.3    Tabata, Y.4    Kimura, H.5
  • 51
    • 0034114629 scopus 로고    scopus 로고
    • Transscleral delivery of bioactive protein to the choroid and retina
    • Ambati J, Gragoudas ES, Miller JW, et al. Transscleral delivery of bioactive protein to the choroid and retina. Invest Ophthalmol Vis Sci 2000; 41(5): 1186-91.
    • (2000) Invest Ophthalmol Vis Sci , vol.41 , Issue.5 , pp. 1186-1191
    • Ambati, J.1    Gragoudas, E.S.2    Miller, J.W.3
  • 52
    • 0026516615 scopus 로고
    • Sustained-release ganciclovir therapy for treatment of cytomegalovirus retinitis
    • Sanborn GE, Anand R, Torti RE, et al. Sustained-release ganciclovir therapy for treatment of cytomegalovirus retinitis. Arch Ophthalmol 1992; 110(2): 188-95.
    • (1992) Arch Ophthalmol , vol.110 , Issue.2 , pp. 188-195
    • Sanborn, G.E.1    Anand, R.2    Torti, R.E.3
  • 53
    • 77957340876 scopus 로고    scopus 로고
    • Biodegradable Implants for Sustained Drug Release in the Eye
    • Lee SS, Hughes P, Ross AD, Robinson MR. Biodegradable Implants for Sustained Drug Release in the Eye. Pharm Res 2010; 27(10): 2043-53.
    • (2010) Pharm Res , vol.27 , Issue.10 , pp. 2043-2053
    • Lee, S.S.1    Hughes, P.2    Ross, A.D.3    Robinson, M.R.4
  • 54
    • 0037809363 scopus 로고    scopus 로고
    • Intraocular tissue distribution of betamethasone after intrascleral administration using a non-biodegradable sustained drug delivery device
    • Okabe K, Kimura H, Okabe J, Kato A, N Kunou, Ogura Y. Intraocular tissue distribution of betamethasone after intrascleral administration using a non-biodegradable sustained drug delivery device. Invest Ophthalmol Vis Sci 2003; 44(6): 2702-7.
    • (2003) Invest Ophthalmol Vis Sci , vol.44 , Issue.6 , pp. 2702-2707
    • Okabe, K.1    Kimura, H.2    Okabe, J.3    Kato, A.4    Kunou, N.5    Ogura, Y.6
  • 55
    • 0033761752 scopus 로고    scopus 로고
    • Fluocinolone acetonide sustained drug delivery device to treat severe uveitis
    • Jaffe GJ, Ben-Nun J, Guo H, Dunn JP, Ashton P. Fluocinolone acetonide sustained drug delivery device to treat severe uveitis. Ophthalmology 2000; 107(11): 2024-33.
    • (2000) Ophthalmology , vol.107 , Issue.11 , pp. 2024-2033
    • Jaffe, G.J.1    Ben-Nun, J.2    Guo, H.3    Dunn, J.P.4    Ashton, P.5
  • 56
    • 0033637677 scopus 로고    scopus 로고
    • Dexamethasone sustained drug delivery implant for the treatment of severe uveitis
    • Jaffe GJ, Pearson PA, Ashton P. Dexamethasone sustained drug delivery implant for the treatment of severe uveitis, Retina 2000; 20(4): 402-3.
    • (2000) Retina , vol.20 , Issue.4 , pp. 402-403
    • Jaffe, G.J.1    Pearson, P.A.2    Ashton, P.3
  • 57
    • 0031909516 scopus 로고    scopus 로고
    • An intravitreal sustained-release triamcinolone and 5-fluorouracil codrug in the treatment of experimental proliferative vitreoretinopathy
    • Yang CS, Khawly JA, Hainsworth DP, et al. An intravitreal sustained-release triamcinolone and 5-fluorouracil codrug in the treatment of experimental proliferative vitreoretinopathy. Arch Ophthalmol 1998; 116(1): 69-77.
    • (1998) Arch Ophthalmol , vol.116 , Issue.1 , pp. 69-77
    • Yang, C.S.1    Khawly, J.A.2    Hainsworth, D.P.3
  • 58
    • 84940187008 scopus 로고    scopus 로고
    • Novel Intraocular Therapy in Non-infectious Uveitis of the Posterior Segment of the Eye
    • Mikhail M, Sallam A. Novel Intraocular Therapy in Non-infectious Uveitis of the Posterior Segment of the Eye. Med Hypothesis Discov Innov Ophthalmol 2013; 2(4): 113-20.
    • (2013) Med Hypothesis Discov Innov Ophthalmol , vol.2 , Issue.4 , pp. 113-120
    • Mikhail, M.1    Sallam, A.2
  • 59
    • 40849097594 scopus 로고    scopus 로고
    • Reimplantation of a fluocinoloneacetonide sustained drug delivery implant for chronic uveitis
    • Jaffe GJ. Reimplantation of a fluocinoloneacetonide sustained drug delivery implant for chronic uveitis. Am J Ophthalmol 2008; 145(4): 667-75.
    • (2008) Am J Ophthalmol , vol.145 , Issue.4 , pp. 667-675
    • Jaffe, G.J.1
  • 60
    • 84877050297 scopus 로고    scopus 로고
    • Fluocinolone acetonide intravitreal implant (Iluvien®). In diabetic macular oedema
    • Sanford M. Fluocinolone acetonide intravitreal implant (Iluvien®). In diabetic macular oedema. Drugs 2013; 73(2): 187-93.
    • (2013) Drugs , vol.73 , Issue.2 , pp. 187-193
    • Sanford, M.1
  • 62
    • 77951218267 scopus 로고    scopus 로고
    • Episcleral Implants for Topotecan Delivery to the Posterior Segment of the Eye
    • Carcaboso AM, Chiappetta DA, Opezzo JA, et al. Episcleral Implants for Topotecan Delivery to the Posterior Segment of the Eye. Invest Ophthalmol Vis Sci 2010; 51(4): 2126-34.
    • (2010) Invest Ophthalmol Vis Sci , vol.51 , Issue.4 , pp. 2126-2134
    • Carcaboso, A.M.1    Chiappetta, D.A.2    Opezzo, J.A.3
  • 63
    • 84896545712 scopus 로고    scopus 로고
    • A polymeric device for controlled transscleral multi-drug delivery to the posterior segment of the eye
    • Nagai N, Kaji H, Onami H, et al. A polymeric device for controlled transscleral multi-drug delivery to the posterior segment of the eye. Acta Biomater 2014; 10(2): 680-7.
    • (2014) Acta Biomater , vol.10 , Issue.2 , pp. 680-687
    • Nagai, N.1    Kaji, H.2    Onami, H.3
  • 64
    • 42249115543 scopus 로고    scopus 로고
    • Recent patents on ocular drug delivery systems
    • Conway BR. Recent patents on ocular drug delivery systems. Recent Pat Drug Deliv Formul 2008; 2(1): 1-8.
    • (2008) Recent Pat Drug Deliv Formul , vol.2 , Issue.1 , pp. 1-8
    • Conway, B.R.1
  • 65
    • 84908513901 scopus 로고    scopus 로고
    • Implants for drug delivery to the posterior segment of the eye: A focus on stimuli-responsive and tunable release systems
    • Yasin MN, Svirskis D, Seyfoddin A, Rupenthal ID. Implants for drug delivery to the posterior segment of the eye: A focus on stimuli-responsive and tunable release systems. J Control Release 2014; 196: 208-21.
    • (2014) J Control Release , vol.196 , pp. 208-221
    • Yasin, M.N.1    Svirskis, D.2    Seyfoddin, A.3    Rupenthal, I.D.4
  • 66
    • 0035980379 scopus 로고    scopus 로고
    • Biodegradable scleral plugs for vitreoretinal drug delivery
    • Yasukawa T, Kimura MDH, Tabat Y, Ogura Y. Biodegradable scleral plugs for vitreoretinal drug delivery. Adv Drug Deliv Rev 2001; 52(1): 25-36.
    • (2001) Adv Drug Deliv Rev , vol.52 , Issue.1 , pp. 25-36
    • Yasukawa, T.1    Kimura, M.2    Tabat, Y.3    Ogura, Y.4
  • 67
    • 0035255910 scopus 로고    scopus 로고
    • Biocompatibility and biodegradation of intravitreal hyaluronan implants in rabbits
    • Avitabile T, Marano F, Castiglione F, et al. Biocompatibility and biodegradation of intravitreal hyaluronan implants in rabbits. Biomaterials 2001; 22(3): 195-200.
    • (2001) Biomaterials , vol.22 , Issue.3 , pp. 195-200
    • Avitabile, T.1    Marano, F.2    Castiglione, F.3
  • 68
    • 38549133515 scopus 로고    scopus 로고
    • Studies on a novel doughnut-shaped mini tablet for intraocular drug delivery
    • Choonara YE, Pillay V, Carmichael T, Danckwerts MP. Studies on a novel doughnut-shaped mini tablet for intraocular drug delivery. AAPS PharmSciTech 2007; 8(4): E118.
    • (2007) AAPS Pharmscitech , vol.8 , Issue.4 , pp. 118
    • Choonara, Y.E.1    Pillay, V.2    Carmichael, T.3    Danckwerts, M.P.4
  • 69
    • 81155135095 scopus 로고    scopus 로고
    • Dexamethasone intravitreal implant for the treatment of noninfectious uveitis
    • Hunter RS, Lobo AM. Dexamethasone intravitreal implant for the treatment of noninfectious uveitis. Clin Ophthalmol 2011; 5: 1613-21.
    • (2011) Clin Ophthalmol , vol.5 , pp. 1613-1621
    • Hunter, R.S.1    Lobo, A.M.2
  • 71
    • 84929202610 scopus 로고    scopus 로고
    • Sustained-Release Corticosteroid Options. Hindawi Publishing Corporation
    • Cabrera M, Yeh S, Albini TA. Sustained-Release Corticosteroid Options. Hindawi Publishing Corporation, J Ophthalmol 2014; 2014: 164692.
    • (2014) J Ophthalmol , vol.2014
    • Cabrera, M.1    Yeh, S.2    Albini, T.A.3
  • 72
    • 84885571516 scopus 로고    scopus 로고
    • Drug delivery implants in the treatment of vitreous inflammation
    • ID 780634
    • Wang J, Jiang A, Joshi M, Christoforidis J. Drug delivery implants in the treatment of vitreous inflammation. Mediat. Inflamm 2013; ID 780634.
    • (2013) Mediat. Inflamm
    • Wang, J.1    Jiang, A.2    Joshi, M.3    Christoforidis, J.4
  • 73
    • 33646192361 scopus 로고    scopus 로고
    • Biocompatible and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids
    • Guse C, Koennings S, Maschke A, et al. Biocompatible and erosion behavior of implants made of triglycerides and blends with cholesterol and phospholipids. Int J Pharm 2006; 314(2): 153-60.
    • (2006) Int J Pharm , vol.314 , Issue.2 , pp. 153-160
    • Guse, C.1    Koennings, S.2    Maschke, A.3
  • 74
    • 84899858922 scopus 로고    scopus 로고
    • Development, characterization and biocompatibility evaluatyion of intravitreal lipid implant
    • Tamaddon L, Mostafavi A, Riazi-Esfahani M, et al. Development, characterization and biocompatibility evaluatyion of intravitreal lipid implant. Jundishapur J Nat Pharm Prod 2014; 9(2): e16414.
    • (2014) Jundishapur J Nat Pharm Prod , vol.9 , Issue.2
    • Tamaddon, L.1    Mostafavi, A.2    Riazi-Esfahani, M.3
  • 75
    • 77149141784 scopus 로고    scopus 로고
    • Biodegradable intraocular therapies for retinal disorders: Progress to date
    • Kuno N, Fujii S. Biodegradable intraocular therapies for retinal disorders: progress to date. Drugs Aging 2010; 27(2): 117-34.
    • (2010) Drugs Aging , vol.27 , Issue.2 , pp. 117-134
    • Kuno, N.1    Fujii, S.2
  • 76
    • 84896720792 scopus 로고    scopus 로고
    • Ocular drug delivery systems for the posterior segment: A review
    • Kuno N, Fujii S. Ocular drug delivery systems for the posterior segment: a review. Retina Today 2012; 5: 54-59.
    • (2012) Retina Today , vol.5 , pp. 54-59
    • Kuno, N.1    Fujii, S.2
  • 77
    • 79960933149 scopus 로고    scopus 로고
    • On-demand controlled release of docetaxel from a battery-less
    • Pirmoradi FN, Jackson JK, Burt HM, Chiao M. On-demand controlled release of docetaxel from a battery-less. Lab Chip 2011; 11(16): 2744-52.
    • (2011) Lab Chip , vol.11 , Issue.16 , pp. 2744-2752
    • Pirmoradi, F.N.1    Jackson, J.K.2    Burt, H.M.3    Chiao, M.4
  • 78
    • 1542604479 scopus 로고    scopus 로고
    • A water-powered micro drug delivery system
    • Su YC, Lin LW. A water-powered micro drug delivery system. J. Microelectromech. Syst 2004; 13: 75-8.
    • (2004) J. Microelectromech. Syst , vol.13 , pp. 75-78
    • Su, Y.C.1    Lin, L.W.2
  • 79
    • 0037122675 scopus 로고    scopus 로고
    • Hydrogels for biomedical applications
    • Hoffman AS. Hydrogels for biomedical applications. Adv Drug Deliv Rev 2002; 54(1): 3-12.
    • (2002) Adv Drug Deliv Rev , vol.54 , Issue.1 , pp. 3-12
    • Hoffman, A.S.1
  • 80
    • 63049131601 scopus 로고    scopus 로고
    • Thermoresponsie hydrogels as new ocular drug delivery platform to the posterior segment of the eye
    • Kang Derwent JJ and Mieler WF. Thermoresponsie hydrogels as new ocular drug delivery platform to the posterior segment of the eye. Trans Am Ophthalmol Soc 2008; 106: 206-14.
    • (2008) Trans am Ophthalmol Soc , vol.106 , pp. 206-214
    • Kang Derwent, J.J.1    Mieler, W.F.2
  • 81
    • 79954520410 scopus 로고    scopus 로고
    • Recent advances in ophthalmic drug delivery
    • Kompella UB, Kadam RS, Lee VHL. Recent advances in ophthalmic drug delivery. Ther Deliv 2010; 1(3): 435-56.
    • (2010) Ther Deliv , vol.1 , Issue.3 , pp. 435-456
    • Kompella, U.B.1    Kadam, R.S.2    Lee, V.H.L.3
  • 82
    • 84861578755 scopus 로고    scopus 로고
    • Celladhesive thermogelling PNIPAAm/hyaluronic acid cell delivery hydrogels for potential application as minimally invasive retinal therapeutics
    • Mazumder MA, Fitzpatrick SD, Muirhead B, Sheardown H. Celladhesive thermogelling PNIPAAm/hyaluronic acid cell delivery hydrogels for potential application as minimally invasive retinal therapeutics. J Biomed Mater Res A 2012; 100(7): 1877-87.
    • (2012) J Biomed Mater Res A , vol.100 , Issue.7 , pp. 1877-1887
    • Mazumder, M.A.1    Fitzpatrick, S.D.2    Muirhead, B.3    Sheardown, H.4
  • 84
    • 77956929706 scopus 로고    scopus 로고
    • Preparation and evaluation of in situ gelling ophthalmic drug delivery system for methazolamide
    • Qian Y, Wang F, Li R, Zhang Q, Xu Q. Preparation and evaluation of in situ gelling ophthalmic drug delivery system for methazolamide. Drug Dev Ind Pharm 2010; 36(11): 1340-7.
    • (2010) Drug Dev Ind Pharm , vol.36 , Issue.11 , pp. 1340-1347
    • Qian, Y.1    Wang, F.2    Li, R.3    Zhang, Q.4    Xu, Q.5
  • 85
    • 79960161195 scopus 로고    scopus 로고
    • Thermosensitive Self-Assembling Block Copolymers as Drug Delivery Systems
    • Bonacucina G, Cespi M, Mencarelli G, Giorgioni G, Palmieri GF. Thermosensitive Self-Assembling Block Copolymers as Drug Delivery Systems. Polymers 2011; 3(2): 779-811
    • (2011) Polymers , vol.3 , Issue.2 , pp. 779-811
    • Bonacucina, G.1    Cespi, M.2    Mencarelli, G.3    Giorgioni, G.4    Palmieri, G.F.5
  • 86
    • 84858801060 scopus 로고    scopus 로고
    • Chitosan-based thermosensitive hydrogel as a promising ocular drug delivery system: Preparation, characterization, and in vivo evaluation
    • Chen X, Li X, Zhou Y, et al. Chitosan-based thermosensitive hydrogel as a promising ocular drug delivery system: preparation, characterization, and in vivo evaluation. J Biomater Appl 2012; 27(4): 391-402.
    • (2012) J Biomater Appl , vol.27 , Issue.4 , pp. 391-402
    • Chen, X.1    Li, X.2    Zhou, Y.3
  • 87
    • 84877636844 scopus 로고    scopus 로고
    • In Situ Gelling System: A Novel Approach for Ocular Drug Delivery
    • Rajoria G, Gupta A. In Situ Gelling System: A Novel Approach for Ocular Drug Delivery. AJPTR 2012; (2): 24-53.
    • (2012) AJPTR , Issue.2 , pp. 24-53
    • Rajoria, G.1    Gupta, A.2
  • 88
    • 77956411053 scopus 로고    scopus 로고
    • PLGA-PEG-PLGA hydrogel for ocular drug delivery of dexamethasone acetate
    • Gao Y, Sun Y, Ren F, Gao S. PLGA-PEG-PLGA hydrogel for ocular drug delivery of dexamethasone acetate. Drug Dev Ind Pharm 2010; 36(10): 1131-8.
    • (2010) Drug Dev Ind Pharm , vol.36 , Issue.10 , pp. 1131-1138
    • Gao, Y.1    Sun, Y.2    Ren, F.3    Gao, S.4
  • 89
    • 84862728671 scopus 로고    scopus 로고
    • Ocular drug delivery system: A reference to natural polymers
    • Pahuja P, Arora S, Pawar P. Ocular drug delivery system: a reference to natural polymers. Expert Opin Drug Deliv 2012; 9(7): 837-61.
    • (2012) Expert Opin Drug Deliv , vol.9 , Issue.7 , pp. 837-861
    • Pahuja, P.1    Arora, S.2    Pawar, P.3
  • 91
    • 84862907578 scopus 로고    scopus 로고
    • Extended release of bevacizumab by thermosensitive biodegradable and biocompatible hydrogel
    • Wang CH, Hwang YS, Chiang PR, Shen CR, Hong WH, Hsiue GH. Extended release of bevacizumab by thermosensitive biodegradable and biocompatible hydrogel. Biomacromolecules 2012; 13(1): 40-8.
    • (2012) Biomacromolecules , vol.13 , Issue.1 , pp. 40-48
    • Wang, C.H.1    Hwang, Y.S.2    Chiang, P.R.3    Shen, C.R.4    Hong, W.H.5    Hsiue, G.H.6
  • 92
    • 84943819063 scopus 로고    scopus 로고
    • Silk hydrogels for sustained ocular delivery of anti-vascular endothelial growth factor (Anti-VEGF) therapeutics
    • Jan 12
    • Lovett ML, Wang X, Yucel T, et al. Silk hydrogels for sustained ocular delivery of anti-vascular endothelial growth factor (anti-VEGF) therapeutics. Eur J Pharm Biopharm 2015 Jan 12. pii: S0939-6411(15)00004-1.
    • (2015) Eur J Pharm Biopharm
    • Lovett, M.L.1    Wang, X.2    Yucel, T.3
  • 93
    • 84893141968 scopus 로고    scopus 로고
    • Biocompatible Reverse Thermal Gel Sustains the Release of Intravitreal Bevacizumab In Vivo
    • Rauck BM, Friberg TR, Medina Mendez CA, et al. Biocompatible Reverse Thermal Gel Sustains the Release of Intravitreal Bevacizumab In Vivo. Invest Ophthalmol Vis Sci 2014; 55(1): 469-76.
    • (2014) Invest Ophthalmol Vis Sci , vol.55 , Issue.1 , pp. 469-476
    • Rauck, B.M.1    Friberg, T.R.2    Medina Mendez, C.A.3
  • 94
    • 84862907578 scopus 로고    scopus 로고
    • Extended release of bevacizumab by thermosensitive biodegradable and biocompatible hydrogel
    • Wang CH, Hwang YS, Chiang PR, Shen CR, Hong WH, Hsiue GH. Extended release of bevacizumab by thermosensitive biodegradable and biocompatible hydrogel. Biomacromolecules 2012; 13(1): 40-8.
    • (2012) Biomacromolecules , vol.13 , Issue.1 , pp. 40-48
    • Wang, C.H.1    Hwang, Y.S.2    Chiang, P.R.3    Shen, C.R.4    Hong, W.H.5    Hsiue, G.H.6
  • 95
    • 84879718965 scopus 로고    scopus 로고
    • Study In Vivo Intraocular Biocompatibility of In Situ Gelation Hydrogels: Poly(2-Ethyl Oxazoline)-Block-Poly(ε-Caprolactone)-Block-Poly(2-Ethyl Oxazoline) Copolymer
    • Hwang YS, Chiang PR, Hong WH, et al. Study In Vivo Intraocular Biocompatibility of In Situ Gelation Hydrogels: Poly(2-Ethyl Oxazoline)-Block-Poly(ε-Caprolactone)-Block-Poly(2-Ethyl Oxazoline) Copolymer. Matrigel and Pluronic F127, PLoS One 2013; 8(7): e67495.
    • (2013) Matrigel and Pluronic F127, Plos One , vol.8 , Issue.7
    • Hwang, Y.S.1    Chiang, P.R.2    Hong, W.H.3
  • 96
    • 77649329002 scopus 로고    scopus 로고
    • Sustained subconjunctival protein delivery using a thermosetting gel delivery system
    • Rieke ER, Amaral J, Becerra SP, Lutz RJ. Sustained subconjunctival protein delivery using a thermosetting gel delivery system. J Ocul Pharmacol Ther 2010; 26(1): 55-64.
    • (2010) J Ocul Pharmacol Ther , vol.26 , Issue.1 , pp. 55-64
    • Rieke, E.R.1    Amaral, J.2    Becerra, S.P.3    Lutz, R.J.4
  • 97
    • 26844494874 scopus 로고    scopus 로고
    • Fabrication and characterization of microgelimpregnated, thermosensitive PNIPAAm hydrogels
    • Zhang XZ, Chu CC. Fabrication and characterization of microgelimpregnated, thermosensitive PNIPAAm hydrogels. Polymer 2005; 46: 9664-73.
    • (2005) Polymer , vol.46 , pp. 9664-9673
    • Zhang, X.Z.1    Chu, C.C.2
  • 98
    • 63049131601 scopus 로고    scopus 로고
    • Thermoresponsive hydrogel as a new ocvular drug delivery platform to the posterior segment of the eye
    • Kang Derwent JJ, Mieler WF. Thermoresponsive hydrogel as a new ocvular drug delivery platform to the posterior segment of the eye. Trans Am Ophthalmol Soc 2008; 106: 206-13.
    • (2008) Trans am Ophthalmol Soc , vol.106 , pp. 206-213
    • Kang Derwent, J.J.1    Mieler, W.F.2
  • 99
    • 79952107113 scopus 로고    scopus 로고
    • The effects of crosslinked thermo-responsive PNIPAAm-based hydrogel injection on retinal function
    • Turturro SB, Guthrie MJ, Appel AA, et al. The effects of crosslinked thermo-responsive PNIPAAm-based hydrogel injection on retinal function. Biomaterials 2011; 32(14): 3620-6.
    • (2011) Biomaterials , vol.32 , Issue.14 , pp. 3620-3626
    • Turturro, S.B.1    Guthrie, M.J.2    Appel, A.A.3
  • 100
    • 70349290518 scopus 로고    scopus 로고
    • Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina
    • Misra GP, Singh RS, Aleman TS, Jacobson SG, Gardner TW, Lowe TL. Subconjunctivally implantable hydrogels with degradable and thermoresponsive properties for sustained release of insulin to the retina. Biomaterials 2009; 30(33): 6541-7.
    • (2009) Biomaterials , vol.30 , Issue.33 , pp. 6541-6547
    • Misra, G.P.1    Singh, R.S.2    Aleman, T.S.3    Jacobson, S.G.4    Gardner, T.W.5    Lowe, T.L.6
  • 101
    • 80054091847 scopus 로고    scopus 로고
    • Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine
    • Prestwich GD. Hyaluronic acid-based clinical biomaterials derived for cell and molecule delivery in regenerative medicine. J Control Release 2011; 155(2): 193-9.
    • (2011) J Control Release , vol.155 , Issue.2 , pp. 193-199
    • Prestwich, G.D.1
  • 103
    • 84871293079 scopus 로고    scopus 로고
    • The application of hyaluronic acid hydrogels to retinal progenitor cell transplantation
    • Liu Y, Wang R, Zarembinski TI, et al. The application of hyaluronic acid hydrogels to retinal progenitor cell transplantation. Tissue Eng Part A 2013; 19(1-2): 135-42.
    • (2013) Tissue Eng Part A , vol.19 , Issue.1-2 , pp. 135-142
    • Liu, Y.1    Wang, R.2    Zarembinski, T.I.3
  • 104
    • 84888645890 scopus 로고    scopus 로고
    • Thiolated hyaluronan-based hydrogels crosslinked using oxidized glutathione: An injectable matrix designed for ophthalmic applications
    • Zarembinski TI, Doty NJ, Erickson IE, Srinivas R, Wirostko BM, Tew WP. Thiolated hyaluronan-based hydrogels crosslinked using oxidized glutathione: An injectable matrix designed for ophthalmic applications. Acta Biomater 2014; 10(1): 94-103.
    • (2014) Acta Biomater , vol.10 , Issue.1 , pp. 94-103
    • Zarembinski, T.I.1    Doty, N.J.2    Erickson, I.E.3    Srinivas, R.4    Wirostko, B.M.5    Tew, W.P.6
  • 105
    • 39149101787 scopus 로고    scopus 로고
    • Ophthalmic light sensitive nanocarrier systems
    • Christie JG, Kompella UB. Ophthalmic light sensitive nanocarrier systems. Drug Discov Today 2008; 13(3-4): 124-34.
    • (2008) Drug Discov Today , vol.13 , Issue.3-4 , pp. 124-134
    • Christie, J.G.1    Kompella, U.B.2
  • 106
    • 85012373035 scopus 로고
    • Diffusion of univalent ions across the lamellae of swollen phospholipids
    • Bangham AD, Standish MM, Watkins JC. Diffusion of univalent ions across the lamellae of swollen phospholipids. J Mol Biol 1965; 13(1): 238-252.
    • (1965) J Mol Biol , vol.13 , Issue.1 , pp. 238-252
    • Bangham, A.D.1    Standish, M.M.2    Watkins, J.C.3
  • 107
    • 14844336918 scopus 로고    scopus 로고
    • Applications of Liposomes in Ophthalmology
    • Ebrahim S, Peyman GA, Lee PJ. Applications of Liposomes in Ophthalmology. Surv Ophthalmol 2005; 50(2): 167-82.
    • (2005) Surv Ophthalmol , vol.50 , Issue.2 , pp. 167-182
    • Ebrahim, S.1    Peyman, G.A.2    Lee, P.J.3
  • 108
    • 84856638259 scopus 로고    scopus 로고
    • Clinical development of liposome-based drugs: Formulation, characterization, and therapeutic efficacy
    • Chang HI, Yeh MK. Clinical development of liposome-based drugs: formulation, characterization, and therapeutic efficacy. Int J Nanomed 2012; 7: 49-60.
    • (2012) Int J Nanomed , vol.7 , pp. 49-60
    • Chang, H.I.1    Yeh, M.K.2
  • 109
    • 84968327810 scopus 로고    scopus 로고
    • Textbook on clinical ocular pharmacology and therapeutics
    • Gupta SK, Agarwal R, Srivastava S. Textbook on clinical ocular pharmacology and therapeutics. JP Medical Ltd 2014; 65-84.
    • (2014) JP Medical Ltd , pp. 65-84
    • Gupta, S.K.1    Agarwal, R.2    Srivastava, S.3
  • 110
    • 77954416176 scopus 로고    scopus 로고
    • Feasibility of lipid nanoparticles for ocular delivery of antiinflammatory drugs
    • Souto EB, Doktorovova S, Gonzalez-Mira E, Egea MA, Garcia ML. Feasibility of lipid nanoparticles for ocular delivery of antiinflammatory drugs. Curr Eye Res 2010; 35(7): 537-52.
    • (2010) Curr Eye Res , vol.35 , Issue.7 , pp. 537-552
    • Souto, E.B.1    Doktorovova, S.2    Gonzalez-Mira, E.3    Egea, M.A.4    Garcia, M.L.5
  • 111
    • 84904649695 scopus 로고    scopus 로고
    • Novel Lutein Loaded Lipid Nanoparticles on Porcine Corneal Distribution
    • Liu CH, Chiu HC, Wu WC, Sahoo SL, Hsu CY. Novel Lutein Loaded Lipid Nanoparticles on Porcine Corneal Distribution. J Ophthalmol 2014; 2014: 304694.
    • (2014) J Ophthalmol , vol.2014
    • Liu, C.H.1    Chiu, H.C.2    Wu, W.C.3    Sahoo, S.L.4    Hsu, C.Y.5
  • 112
    • 41349106751 scopus 로고    scopus 로고
    • Diclofenac sodium delivery to the eye: In vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct
    • Attama AA, Reichl S, Müller-Goymann CC. Diclofenac sodium delivery to the eye: In vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct. Int J Pharm 2008; 355(1-2): 307-13.
    • (2008) Int J Pharm , vol.355 , Issue.1-2 , pp. 307-313
    • Attama, A.A.1    Reichl, S.2    Müller-Goymann, C.C.3
  • 113
    • 84886867429 scopus 로고    scopus 로고
    • Fabrication of a composite system combining solid lipid nanoparticles and thermosensitive hydrogel for challenging ophthalmic drug delivery
    • Hao J, Wang X, Bi Y, et al. Fabrication of a composite system combining solid lipid nanoparticles and thermosensitive hydrogel for challenging ophthalmic drug delivery. Colloids Surf B Biointerfaces 2014; 114: 111-20.
    • (2014) Colloids Surf B Biointerfaces , vol.114 , pp. 111-120
    • Hao, J.1    Wang, X.2    Bi, Y.3
  • 114
    • 77953356716 scopus 로고    scopus 로고
    • Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications
    • Araújo J, Gonzalez-Mira E, Egea MA, Garcia ML, Souto EB. Optimization and physicochemical characterization of a triamcinolone acetonide-loaded NLC for ocular antiangiogenic applications. Int J Pharm 2010; 393(1-2): 167-75.
    • (2010) Int J Pharm , vol.393 , Issue.1-2 , pp. 167-175
    • Araújo, J.1    Gonzalez-Mira, E.2    Egea, M.A.3    Garcia, M.L.4    Souto, E.B.5
  • 116
    • 84901986883 scopus 로고    scopus 로고
    • Topical drug delivery to retinal pigment epithelium with microfluidizer produced small liposomes
    • Lajunen T, Hisazumi K, Kanazawa T, et al. Topical drug delivery to retinal pigment epithelium with microfluidizer produced small liposomes. Eur J Pharm Sci 2014; 62: 23-32.
    • (2014) Eur J Pharm Sci , vol.62 , pp. 23-32
    • Lajunen, T.1    Hisazumi, K.2    Kanazawa, T.3
  • 119
    • 84968327804 scopus 로고    scopus 로고
    • Treatise on Ocular Drug Delivery. Chapter 5-Biodegradable polymers for ophthalmic application
    • Mitra AK. Treatise on Ocular Drug Delivery. Chapter 5-Biodegradable polymers for ophthalmic application. Bentham Science Publishers 2013; 96-114.
    • (2013) Bentham Science Publishers , pp. 96-114
    • Mitra, A.K.1
  • 120
    • 3543046202 scopus 로고    scopus 로고
    • Chitosan nanoparticles as new ocular drug delivery systems: In vitro stability, in vivo fate, and cellular toxicity
    • de Campos AM, Diebold Y, Carvalho EL, Sánchez A, Alonso MJ. Chitosan nanoparticles as new ocular drug delivery systems: in vitro stability, in vivo fate, and cellular toxicity. Pharm Res 2004; 21(5): 803-10.
    • (2004) Pharm Res , vol.21 , Issue.5 , pp. 803-810
    • De Campos, A.M.1    Diebold, Y.2    Carvalho, E.L.3    Sánchez, A.4    Alonso, M.J.5
  • 121
    • 84940673008 scopus 로고    scopus 로고
    • Ketorolac Tromethamine Loaded Chitosan Nanoparticles as a Nanotherapeutic System for Ocular Diseases
    • Aȿιk MD, Uğurlu N, Yülek F, Tuncer S, Türk M, Baki ED. Ketorolac Tromethamine Loaded Chitosan Nanoparticles as a Nanotherapeutic System for Ocular Diseases. Hacettepe J Biol Chem 2013, 41 (1): 81-6.
    • (2013) Hacettepe J Biol Chem , vol.41 , Issue.1 , pp. 81-86
    • Aȿιk, M.D.1    Uğurlu, N.2    Yülek, F.3    Tuncer, S.4    Türk, M.5    Baki, E.D.6
  • 123
    • 84942930709 scopus 로고    scopus 로고
    • Chitosan nanoparticles for daptomycin delivery in ocular treatment of bacterial endophthalmitis
    • Silva NC, Silva S, Sarmento B, Pintado M. Chitosan nanoparticles for daptomycin delivery in ocular treatment of bacterial endophthalmitis. Drug Deliv 2015; 22: 1-9.
    • (2015) Drug Deliv , vol.22 , pp. 1-9
    • Silva, N.C.1    Silva, S.2    Sarmento, B.3    Pintado, M.4
  • 124
    • 84890491230 scopus 로고    scopus 로고
    • In situ gelling dorzolamide loaded chitosan nanoparticles for the treatment of glaucoma
    • Katiyar S, Pandit J, Mondal RS, et al. In situ gelling dorzolamide loaded chitosan nanoparticles for the treatment of glaucoma. Carbohydr Polym 2014; 102: 117-24.
    • (2014) Carbohydr Polym , vol.102 , pp. 117-124
    • Katiyar, S.1    Pandit, J.2    Mondal, R.S.3
  • 125
    • 84881322627 scopus 로고    scopus 로고
    • Preparation of bromfenac-loaded liposomes modified with chitosan for ophthalmic drug delivery and evaluation of physicochemical properties and drug release profile
    • Tsukamoto T, Hironaka K, Fujisawa T, et al. Preparation of bromfenac-loaded liposomes modified with chitosan for ophthalmic drug delivery and evaluation of physicochemical properties and drug release profile. Asian J Pharm Sci 2013; 8: 104-9.
    • (2013) Asian J Pharm Sci , vol.8 , pp. 104-109
    • Tsukamoto, T.1    Hironaka, K.2    Fujisawa, T.3
  • 126
    • 84866499684 scopus 로고    scopus 로고
    • Chitosan coated sodium alginate-chitosan nanoparticles loaded with 5-FU for ocular delivery: In vitro characterization and in vivo study in rabbit eye
    • Nagarwal RC, Kumar R, Pandit JK. Chitosan coated sodium alginate-chitosan nanoparticles loaded with 5-FU for ocular delivery: In vitro characterization and in vivo study in rabbit eye. Eur J Pharm Sci 2012; 47(4): 678-85.
    • (2012) Eur J Pharm Sci , vol.47 , Issue.4 , pp. 678-685
    • Nagarwal, R.C.1    Kumar, R.2    Pandit, J.K.3
  • 127
    • 39849100697 scopus 로고    scopus 로고
    • Chitosan-sodium alginate nanoparticles as submicroscopic reservoirs for ocular delivery: Formulation, optimisation and in vitro characterisation
    • Motwani SK, Chopra S, Talegaonkar S, Kohli K, Ahmad FJ, Khar RK. Chitosan-sodium alginate nanoparticles as submicroscopic reservoirs for ocular delivery: Formulation, optimisation and in vitro characterisation. Eur J Pharm Biopharm 2008; 68(3): 513-25.
    • (2008) Eur J Pharm Biopharm , vol.68 , Issue.3 , pp. 513-525
    • Motwani, S.K.1    Chopra, S.2    Talegaonkar, S.3    Kohli, K.4    Ahmad, F.J.5    Khar, R.K.6
  • 128
    • 77951111096 scopus 로고    scopus 로고
    • Hyaluronic acid modified chitosan nanoparticles for effective management of glaucoma: Development, characterization, and evaluation
    • Wadhwa S, Paliwal R, Paliwal SR, Vyas SP. Hyaluronic acid modified chitosan nanoparticles for effective management of glaucoma: development, characterization, and evaluation. J Drug Target 2010; 18(4): 292-302.
    • (2010) J Drug Target , vol.18 , Issue.4 , pp. 292-302
    • Wadhwa, S.1    Paliwal, R.2    Paliwal, S.R.3    Vyas, S.P.4
  • 129
    • 84883250012 scopus 로고    scopus 로고
    • Cationic coreshell nanoparticles with carmustine contained within O6-benzylguanine shell for glioma therapy
    • Qian L, Zheng J, Wang K, et al. Cationic coreshell nanoparticles with carmustine contained within O6-benzylguanine shell for glioma therapy. Biomaterials 2013; 34(35): 8968-78.
    • (2013) Biomaterials , vol.34 , Issue.35 , pp. 8968-8978
    • Qian, L.1    Zheng, J.2    Wang, K.3
  • 130
    • 33846809312 scopus 로고    scopus 로고
    • Encapsulation of dexamethasone into biodegradable polymeric nanoparticles
    • Gomez-Gaete C, Tsapis N, Besnard M, Bochot A, Fattal E. Encapsulation of dexamethasone into biodegradable polymeric nanoparticles. Int J Pharm 2007; 331: 153-9.
    • (2007) Int J Pharm , vol.331 , pp. 153-159
    • Gomez-Gaete, C.1    Tsapis, N.2    Besnard, M.3    Bochot, A.4    Fattal, E.5
  • 131
    • 34248630510 scopus 로고    scopus 로고
    • Effect of lactide/glycolide ratio on the in vitro release of ganciclovir and its lipophilic prodrug (GCVmonobutyrate) from PLGA microspheres
    • Janoria KG, Mitra AK. Effect of lactide/glycolide ratio on the in vitro release of ganciclovir and its lipophilic prodrug (GCVmonobutyrate) from PLGA microspheres. Int J Pharm 2007; 338(1-2): 133-41.
    • (2007) Int J Pharm , vol.338 , Issue.1-2 , pp. 133-141
    • Janoria, K.G.1    Mitra, A.K.2


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