Ferroptosis is Involved in Acetaminophen Induced Cell Death

Pathology and Oncology Research

Volumn 21, Issue 4, 2015, Pages 1115-1121

  Lőrincz, Tamás ^a   Jemnitz, Katalin ^b   Kardon, Tamás ^b   Mandl, József ^b   Szarka, András ^a,b  

^a BUDAPEST UNIVERSITY OF TECHNOLOGY AND ECONOMICS   (Hungary)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

Author keywords

Acetaminophen; Ferroptosis; Glutathione; Hepatotoxicity; Necroptosis

Indexed keywords

CYTOCHROME P450 2E1; FERROSTATIN 1; GLUTATHIONE; NECROSTATIN 1; PARACETAMOL; PROTEIN INHIBITOR; UNCLASSIFIED DRUG; BENZOQUINONE DERIVATIVE; CYCLOHEXYLAMINE DERIVATIVE; FERROSTATIN-1; GLUTATHIONE PEROXIDASE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; IMIDAZOLE DERIVATIVE; IMINE; INDOLE DERIVATIVE; N-ACETYL-4-BENZOQUINONEIMINE; NECROSTATIN-1; PHENYLENEDIAMINE DERIVATIVE; RALBP1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL VIABILITY; FERROPTOSIS; HEPG2 CELL LINE; LIVER CELL; LIVER TOXICITY; MALE; MOUSE; NECROPTOSIS; NONHUMAN; PROTEIN EXPRESSION; ANIMAL; CELL SURVIVAL; DRUG EFFECTS; HUMAN; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

ACETAMINOPHEN; ANIMALS; APOPTOSIS; BENZOQUINONES; CELL DEATH; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOHEXYLAMINES; CYTOCHROME P-450 CYP2E1; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GTPASE-ACTIVATING PROTEINS; HEP G2 CELLS; HEPATOCYTES; HUMANS; IMIDAZOLES; IMINES; INDOLES; MALE; MICE; PHENYLENEDIAMINES;

EID: 84940449718     PISSN: 12194956     EISSN: 15322807     Source Type: Journal    
DOI: 10.1007/s12253-015-9946-3     Document Type: Article

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