Melatonin Activates Endoplasmic Reticulum Stress and Apoptosis in Rats with Diethylnitrosamine-Induced Hepatocarcinogenesis

PLoS ONE

Volumn 10, Issue 12, 2015, Pages

  Moreira, Andrea Janz ^a,b   Ordoñez, Raquel ^d   Cerski, Carlos Thadeu ^a,b   Picada, Jaqueline Nascimento ^c   García Palomo, Andrés ^e   Marroni, Norma Possa ^a,b,c   Mauriz, Jose L ^d   González Gallego, Javier ^d  

^a HOSPITAL DE CLÍNICAS DE PORTO ALEGRE   (Brazil)

^b FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^c UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

^d UNIVERSITY OF LEÓN   (Spain)

^e Departamento de Cardiología   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; CASPASE 3; CASPASE 8; CASPASE 9; CYCLOOXYGENASE 2; CYTOCHROME C; DIETHYLNITROSAMINE; FAS LIGAND; GLUCOSE REGULATED PROTEIN 78; GLUTATHIONE TRANSFERASE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MELATONIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; TUMOR MARKER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER SURVIVAL; CONTROLLED STUDY; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; ENZYME BLOOD LEVEL; ENZYME MODIFICATION; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER INJURY; MALE; NONHUMAN; RAT; SIGNAL TRANSDUCTION; SURVIVAL RATE; TREATMENT DURATION; ANIMAL; BLOOD; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; COMET ASSAY; DRUG EFFECTS; LIVER TUMOR; METABOLISM; PATHOLOGY; WISTAR RAT;

ANIMALS; APOPTOSIS; BIOMARKERS, TUMOR; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; COMET ASSAY; CYCLOOXYGENASE 2; DIETHYLNITROSAMINE; ENDOPLASMIC RETICULUM STRESS; LIVER NEOPLASMS; MALE; MELATONIN; RATS, WISTAR;

EID: 84957109743     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0144517     Document Type: Article

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