메뉴 건너뛰기




Volumn 54, Issue 3, 2011, Pages 857-867

Saffron: A potential candidate for a novel anticancer drug against hepatocellular carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ALPHA FETOPROTEIN; ANTINEOPLASTIC AGENT; ANTIOXIDANT; CARBONYL DERIVATIVE; CASPASE 3; CATALASE; CYCLOOXYGENASE 2; DIETHYLNITROSAMINE; DNA NUCLEOTIDYLEXOTRANSFERASE; GAMMA GLUTAMYLTRANSFERASE; GLUTATHIONE TRANSFERASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; KI 67 ANTIGEN; MALONALDEHYDE; MYELOPEROXIDASE; SAFFRON; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR RECEPTOR; UNCLASSIFIED DRUG;

EID: 80052033921     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.24433     Document Type: Article
Times cited : (164)

References (27)
  • 1
    • 70449521967 scopus 로고    scopus 로고
    • Diethylnitrosamine (DEN) induces irreversible hepatocellular carcinogenesis through overexpression of G1/S-phase regulatory proteins in rat
    • Park DH, Shin JW, Park SK, Seo JN, Li L, Jang JJ, et al. Diethylnitrosamine (DEN) induces irreversible hepatocellular carcinogenesis through overexpression of G1/S-phase regulatory proteins in rat. Toxicol Lett 2009; 191: 321-326.
    • (2009) Toxicol Lett , vol.191 , pp. 321-326
    • Park, D.H.1    Shin, J.W.2    Park, S.K.3    Seo, J.N.4    Li, L.5    Jang, J.J.6
  • 2
    • 23944436009 scopus 로고    scopus 로고
    • Magnetic resonance imaging of hepatocellular carcinoma induced by diethylnitrosamine in Sprague-Dawley rats
    • Li X, Zhou XP, Guan YS, Wang YX. Magnetic resonance imaging of hepatocellular carcinoma induced by diethylnitrosamine in Sprague-Dawley rats. Hepatobiliary Pancreat Dis Int 2005; 4: 427-432.
    • (2005) Hepatobiliary Pancreat Dis Int , vol.4 , pp. 427-432
    • Li, X.1    Zhou, X.P.2    Guan, Y.S.3    Wang, Y.X.4
  • 4
    • 9644268896 scopus 로고    scopus 로고
    • Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials
    • Abdullaev FI, Espinosa-Aguirre JJ. Biomedical properties of saffron and its potential use in cancer therapy and chemoprevention trials. Cancer Detect Prev 2004; 28: 426-432.
    • (2004) Cancer Detect Prev , vol.28 , pp. 426-432
    • Abdullaev, F.I.1    Espinosa-Aguirre, J.J.2
  • 5
    • 0036377909 scopus 로고    scopus 로고
    • Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.)
    • Abdullaev FI. Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.). Exp Biol Med (Maywood) 2001; 227: 20-25.
    • (2001) Exp Biol Med (Maywood) , vol.227 , pp. 20-25
    • Abdullaev, F.I.1
  • 6
    • 77953536106 scopus 로고    scopus 로고
    • Saffron suppresses oxidative stress in DMBA-induced skin carcinoma: A histopathological study
    • Das I, Das S, Saha T. Saffron suppresses oxidative stress in DMBA-induced skin carcinoma: A histopathological study. Acta Histochem 2010; 112: 317-327.
    • (2010) Acta Histochem , vol.112 , pp. 317-327
    • Das, I.1    Das, S.2    Saha, T.3
  • 7
    • 10044241824 scopus 로고    scopus 로고
    • Comparison of different initiation protocols in the resistant hepatocyte model
    • Espandiari P, Robertson LW, Srinivasan C, Glauert HP. Comparison of different initiation protocols in the resistant hepatocyte model. Toxicology 2005; 206: 373-381.
    • (2005) Toxicology , vol.206 , pp. 373-381
    • Espandiari, P.1    Robertson, L.W.2    Srinivasan, C.3    Glauert, H.P.4
  • 8
    • 0141746538 scopus 로고    scopus 로고
    • Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice
    • Hosseinzadeh H, Younesi HM. Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice. BMC Pharmacol 2002; 2: 1-8.
    • (2002) BMC Pharmacol , vol.2 , pp. 1-8
    • Hosseinzadeh, H.1    Younesi, H.M.2
  • 9
    • 65349159727 scopus 로고    scopus 로고
    • Clinical implications of alpha-fetoprotein in chronic hepatitis C
    • Tai W, Hu T, Wang J, Hung C, Lu S, Changchien C, et al. Clinical implications of alpha-fetoprotein in chronic hepatitis C. J Formos Med Assoc 2009; 108: 210-218.
    • (2009) J Formos Med Assoc , vol.108 , pp. 210-218
    • Tai, W.1    Hu, T.2    Wang, J.3    Hung, C.4    Lu, S.5    Changchien, C.6
  • 10
    • 0018069570 scopus 로고
    • Determination of malonaldehyde precursor in tissues by thiobarbituric acid test
    • Uchiyama M, Mihara M. Determination of malonaldehyde precursor in tissues by thiobarbituric acid test. Anal Biochem 1978; 86: 271-278.
    • (1978) Anal Biochem , vol.86 , pp. 271-278
    • Uchiyama, M.1    Mihara, M.2
  • 11
    • 0028239163 scopus 로고
    • Oxidative damage to proteins: spectrophotometric method for carbonyl assay
    • Reznick AZ, Packer L. Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Methods Enzymol 1994; 233: 357-363.
    • (1994) Methods Enzymol , vol.233 , pp. 357-363
    • Reznick, A.Z.1    Packer, L.2
  • 13
    • 0021318441 scopus 로고
    • Catalase in vitro
    • Aebi H. Catalase in vitro. Methods Enzymol 1984; 105: 121-126.
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 14
    • 51649151855 scopus 로고
    • Assay of superoxide dismutase activity in animal tissues
    • Nandi A, Chatterjee IB. Assay of superoxide dismutase activity in animal tissues. J Biosci 1988; 13: 305-315.
    • (1988) J Biosci , vol.13 , pp. 305-315
    • Nandi, A.1    Chatterjee, I.B.2
  • 15
    • 0018225140 scopus 로고
    • Synergistic effects of phorone on the hepatotoxicity of bromobenzene and paracetamol in mice
    • Van Dooran R, Leijdekkers CM, Henderson PT. Synergistic effects of phorone on the hepatotoxicity of bromobenzene and paracetamol in mice. Toxicology 1978; 11: 225-233.
    • (1978) Toxicology , vol.11 , pp. 225-233
    • Van Dooran, R.1    Leijdekkers, C.M.2    Henderson, P.T.3
  • 16
    • 0016275313 scopus 로고
    • Glutathione-S-transferases. The first enzymatic step in mercapturic acid formation
    • Habig WH, Pabst MJ, Jakoby WB. Glutathione-S-transferases. The first enzymatic step in mercapturic acid formation. J Biol Chem 1974; 249: 7130-7139.
    • (1974) J Biol Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jakoby, W.B.3
  • 17
    • 0017613512 scopus 로고
    • A simplification of the protein assay method of Lowry which is more generally applicable
    • Peterson GL. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem 1977; 83: 346-356.
    • (1977) Anal Biochem , vol.83 , pp. 346-356
    • Peterson, G.L.1
  • 18
    • 0033984235 scopus 로고    scopus 로고
    • The Ki-67 protein: From the known and unknown
    • Scholzen T, Gerdes J. The Ki-67 protein: From the known and unknown. J Cell Physiol 2000; 182: 311-322.
    • (2000) J Cell Physiol , vol.182 , pp. 311-322
    • Scholzen, T.1    Gerdes, J.2
  • 19
    • 0020644899 scopus 로고
    • Distinctive biochemical pattern associated with resistance hepatocytes in hepatocyte nodules during liver carcinogenesis
    • Eriksson L, Ahluwalia M, Spiewak J, Lee G, Sarma DSR, Roomi MJ, et al. Distinctive biochemical pattern associated with resistance hepatocytes in hepatocyte nodules during liver carcinogenesis. Environ Health Perspect 1983; 49: 171-174.
    • (1983) Environ Health Perspect , vol.49 , pp. 171-174
    • Eriksson, L.1    Ahluwalia, M.2    Spiewak, J.3    Lee, G.4    Sarma, D.S.R.5    Roomi, M.J.6
  • 20
  • 22
    • 36749043785 scopus 로고    scopus 로고
    • Crocin from crocus sativus possesses significant anti-proliferation effects on human colorectal cancer cells
    • Aung HH, Wang CZ, Ni M, Fishbein A, Mehendale SR, Xie JT, et al. Crocin from crocus sativus possesses significant anti-proliferation effects on human colorectal cancer cells. Exp Oncol 2007; 29: 175-180.
    • (2007) Exp Oncol , vol.29 , pp. 175-180
    • Aung, H.H.1    Wang, C.Z.2    Ni, M.3    Fishbein, A.4    Mehendale, S.R.5    Xie, J.T.6
  • 23
    • 77957307234 scopus 로고    scopus 로고
    • Evaluation of Crocus sativus L. stigma phenolic and flavonoid compounds and its antioxidant activity
    • Karimi E, Oskoueian E, Hendra R, Jaafar HZ. Evaluation of Crocus sativus L. stigma phenolic and flavonoid compounds and its antioxidant activity. Molecules 2010; 15: 6244-6256.
    • (2010) Molecules , vol.15 , pp. 6244-6256
    • Karimi, E.1    Oskoueian, E.2    Hendra, R.3    Jaafar, H.Z.4
  • 24
    • 27844479656 scopus 로고    scopus 로고
    • Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals
    • Kundu JK, Surh YJ. Breaking the relay in deregulated cellular signal transduction as a rationale for chemoprevention with anti-inflammatory phytochemicals. Mutat Res 2005; 591: 123-146.
    • (2005) Mutat Res , vol.591 , pp. 123-146
    • Kundu, J.K.1    Surh, Y.J.2
  • 25
    • 43849102348 scopus 로고    scopus 로고
    • Myloperoxidase: A new biomarker of inflammation in ischemic heart disease and acute coronary syndromes
    • Loria V, Dato I, Graziani F, Biasucci LM. Myloperoxidase: A new biomarker of inflammation in ischemic heart disease and acute coronary syndromes. Mediators Inflamm 2008; 2008: 135625.
    • (2008) Mediators Inflamm , vol.2008 , pp. 135625
    • Loria, V.1    Dato, I.2    Graziani, F.3    Biasucci, L.M.4
  • 26
    • 0034084163 scopus 로고    scopus 로고
    • Phosphorylation meets ubiquitination: the control of NF-kB activity
    • Karin M, Ben-Neriah Y. Phosphorylation meets ubiquitination: the control of NF-kB activity. Annu Rev Immunol 2008; 18: 621-663.
    • (2008) Annu Rev Immunol , vol.18 , pp. 621-663
    • Karin, M.1    Ben-Neriah, Y.2
  • 27
    • 0035451363 scopus 로고    scopus 로고
    • Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kB activation
    • Surh YJ, Chun KS, Cha HH, Han SS, Keum YS, Park KK, et al. Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kB activation. Mutat Res 2001; 480-481: 243-268.
    • (2001) Mutat Res , vol.480-481 , pp. 243-268
    • Surh, Y.J.1    Chun, K.S.2    Cha, H.H.3    Han, S.S.4    Keum, Y.S.5    Park, K.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.