Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease

Journal of Neuroinflammation

Volumn 13, Issue 1, 2016, Pages

  Couturier, Julien ^a   Stancu, Ilie Cosmin ^a   Schakman, Olivier ^a   Pierrot, Nathalie ^a   Huaux, François ^a   Kienlen Campard, Pascal ^a   Dewachter, Ilse ^a   Octave, Jean Noël ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

Author keywords

Alzheimer disease; Amyloid ; ASC; Astrocytes; CCL3; Inflammasome; Phagocytosis

Indexed keywords

ADAPTOR PROTEIN; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN CONTAINING CARD DOMAIN; CATHEPSIN B; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; UNCLASSIFIED DRUG; AMYLOID BETA-PROTEIN (1-42); AMYLOID PRECURSOR PROTEIN; APOPTOSIS REGULATORY PROTEIN; CYTOKINE; IONOPHORE; NIGERICIN; PEPTIDE FRAGMENT; PRESENILIN 1; PSEN1 PROTEIN, HUMAN; PYCARD PROTEIN, MOUSE;

ALZHEIMER DISEASE; AMNESIA; ARTICLE; ASTROCYTE; ASTROCYTE CULTURE; CHEMILUMINESCENCE IMMUNOASSAY; CONTROLLED STUDY; CYTOKINE RELEASE; DISEASE ASSOCIATION; MORRIS WATER MAZE TEST; MOUSE; NEWBORN; NONHUMAN; PHAGOCYTOSIS; PROTEIN EXPRESSION; PROTEIN MOTIF; REAL TIME POLYMERASE CHAIN REACTION; REFERENCE MEMORY; SPATIAL MEMORY; ANIMAL; C57BL MOUSE; CASE CONTROL STUDY; CELL CULTURE; COMPLICATION; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MEMORY DISORDERS; METABOLISM; MUTATION; PATHOLOGY; PHAGOCYTE; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANIMALS, NEWBORN; APOPTOSIS REGULATORY PROTEINS; ASTROCYTES; CASE-CONTROL STUDIES; CELLS, CULTURED; CHEMOKINE CCL3; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HUMANS; IONOPHORES; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; NIGERICIN; PEPTIDE FRAGMENTS; PHAGOCYTES; PRESENILIN-1;

EID: 84957109616     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-016-0477-y     Document Type: Article

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