NLRP3 inflammasome is expressed by astrocytes in the SOD1 mouse model of ALS and in human sporadic ALS patients

GLIA

Volumn 63, Issue 12, 2015, Pages 2260-2273

  Johann, Sonja ^a   Heitzer, Marius ^a   Kanagaratnam, Mithila ^a   Goswami, Anand ^a   Rizo, Tania ^a   Weis, Joachim ^a   Troost, Dirk ^b   Beyer, Cordian ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

Amyotrophic lateral sclerosis; Caspase 1; Glia; IL 1b; Neuroinflammation; SOD1(G93A)

Indexed keywords

APOPTOSIS ASSOCIATED SPECK LIKE PROTEIN; COPPER ZINC SUPEROXIDE DISMUTASE; CRYOPYRIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; PEPTIDES AND PROTEINS; UNCLASSIFIED DRUG; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; IL1B PROTEIN, MOUSE; INTERLEUKIN 1BETA CONVERTING ENZYME; MESSENGER RNA; NLRP3 PROTEIN, HUMAN; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTROCYTE; CONTROLLED STUDY; FEMALE; GLIA; HUMAN; HUMAN CELL; HUMAN TISSUE; MALE; MOTONEURON; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SPINAL CORD; ANIMAL; CELL CULTURE; DISEASE MODEL; GENETICS; METABOLISM; PATHOLOGY; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ASTROCYTES; CARRIER PROTEINS; CASPASE 1; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HUMANS; INTERLEUKIN-18; INTERLEUKIN-1BETA; MALE; MICE, TRANSGENIC; MOTOR NEURONS; RNA, MESSENGER; SPINAL CORD; SUPEROXIDE DISMUTASE;

EID: 84943579823     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22891     Document Type: Article

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