메뉴 건너뛰기




Volumn 291, Issue 5, 2016, Pages 2510-2523

Astrocyte resilience to oxidative stress induced by insulin-like growth factor i (IGF-I) involves preserved AKT (protein kinase B) activity

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELL DEATH; CELL MEMBRANES; CHEMICAL ACTIVATION; CHEMICAL COMPOUNDS; ENZYMES; INSULIN; OXIDATIVE STRESS; PROTEINS;

EID: 84957006670     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.695478     Document Type: Article
Times cited : (21)

References (70)
  • 1
    • 33644806375 scopus 로고    scopus 로고
    • Role of insulin-like growth factors in neuronal plasticity and neuroprotection
    • Torres Aleman, I. (2005) Role of insulin-like growth factors in neuronal plasticity and neuroprotection. Adv. Exp. Med. Biol. 567, 243-258
    • (2005) Adv. Exp. Med. Biol. , vol.567 , pp. 243-258
    • Torres Aleman, I.1
  • 2
    • 0034518163 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 (IGF-1): A neuroprotective trophic factor acting via the Akt kinase pathway
    • Zheng, W. H., Kar, S., Dore, S., and Quirion, R. (2000) Insulin-like growth factor-1 (IGF-1): a neuroprotective trophic factor acting via the Akt kinase pathway. J. Neural Transm. Suppl. 261-272
    • (2000) J. Neural Transm. Suppl. , pp. 261-272
    • Zheng, W.H.1    Kar, S.2    Dore, S.3    Quirion, R.4
  • 3
    • 0032752063 scopus 로고    scopus 로고
    • Cellular survival: A play in three Akts
    • Datta, S. R., Brunet, A., and Greenberg, M. E. (1999) Cellular survival: a play in three Akts. Genes Dev. 13, 2905-2927
    • (1999) Genes Dev. , vol.13 , pp. 2905-2927
    • Datta, S.R.1    Brunet, A.2    Greenberg, M.E.3
  • 5
    • 0032143284 scopus 로고    scopus 로고
    • Phosphoinositide 3-kinase: The key switch mechanism in insulin signalling
    • Shepherd, P. R., Withers, D. J., and Siddle, K. (1998) Phosphoinositide 3-kinase: the key switch mechanism in insulin signalling. Biochem. J. 333, 471-490
    • (1998) Biochem. J. , vol.333 , pp. 471-490
    • Shepherd, P.R.1    Withers, D.J.2    Siddle, K.3
  • 6
    • 13844312400 scopus 로고    scopus 로고
    • Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
    • Sarbassov, D. D., Guertin, D. A., Ali, S. M., and Sabatini, D. M. (2005) Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307, 1098-1101
    • (2005) Science , vol.307 , pp. 1098-1101
    • Sarbassov, D.D.1    Guertin, D.A.2    Ali, S.M.3    Sabatini, D.M.4
  • 7
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Dröge, W. (2002) Free radicals in the physiological control of cell function. Physiol. Rev. 82, 47-95
    • (2002) Physiol. Rev. , vol.82 , pp. 47-95
    • Dröge, W.1
  • 9
    • 48249083398 scopus 로고    scopus 로고
    • Neuronal death by oxidative stress involves activation of FOXO3 through a two-arm pathway that activates stress kinases and attenuates insulin-like growth factor i signaling
    • Dávila, D., and Torres-Aleman, I. (2008) Neuronal death by oxidative stress involves activation of FOXO3 through a two-arm pathway that activates stress kinases and attenuates insulin-like growth factor I signaling. Mol. Biol. Cell 19, 2014-2025
    • (2008) Mol. Biol. Cell , vol.19 , pp. 2014-2025
    • Dávila, D.1    Torres-Aleman, I.2
  • 11
    • 34848895134 scopus 로고    scopus 로고
    • Hydrogen peroxide attenuates insulinlike growth factor-1 neuroprotective effect, prevented by minocycline
    • Zhong, J., and Lee, W. H. (2007) Hydrogen peroxide attenuates insulinlike growth factor-1 neuroprotective effect, prevented by minocycline. Neurochem. Int. 51, 398-404
    • (2007) Neurochem. Int. , vol.51 , pp. 398-404
    • Zhong, J.1    Lee, W.H.2
  • 12
    • 70450274965 scopus 로고    scopus 로고
    • Oxidative stress inhibits insulinlike growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-kinase-Akt and MEK-ERK MAPK signaling pathways
    • Yin, W., Park, J. I., and Loeser, R. F. (2009) Oxidative stress inhibits insulinlike growth factor-I induction of chondrocyte proteoglycan synthesis through differential regulation of phosphatidylinositol 3-kinase-Akt and MEK-ERK MAPK signaling pathways. J. Biol. Chem. 284, 31972-31981
    • (2009) J. Biol. Chem. , vol.284 , pp. 31972-31981
    • Yin, W.1    Park, J.I.2    Loeser, R.F.3
  • 13
    • 0035978884 scopus 로고    scopus 로고
    • Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans
    • Braeckman, B. P., Houthoofd, K., and Vanfleteren, J. R. (2001) Insulin-like signaling, metabolism, stress resistance and aging in Caenorhabditis elegans. Mech. Ageing Dev. 122, 673-693
    • (2001) Mech. Ageing Dev. , vol.122 , pp. 673-693
    • Braeckman, B.P.1    Houthoofd, K.2    Vanfleteren, J.R.3
  • 15
    • 41249094424 scopus 로고    scopus 로고
    • How does suppression of IGF-1 signaling by DNA damage affect aging and longevity?
    • Hinkal, G., and Donehower, L. A. (2008) How does suppression of IGF-1 signaling by DNA damage affect aging and longevity? Mech. Ageing Dev. 129, 243-253
    • (2008) Mech. Ageing Dev. , vol.129 , pp. 243-253
    • Hinkal, G.1    Donehower, L.A.2
  • 17
    • 84904892173 scopus 로고    scopus 로고
    • Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington's disease knock-in striatal cells
    • Ribeiro, M., Rosenstock, T. R., Oliveira, A. M., Oliveira, C. R., and Rego, A. C. (2014) Insulin and IGF-1 improve mitochondrial function in a PI-3K/Akt-dependent manner and reduce mitochondrial generation of reactive oxygen species in Huntington's disease knock-in striatal cells. Free Radic. Biol. Med. 74, 129-144
    • (2014) Free Radic. Biol. Med. , vol.74 , pp. 129-144
    • Ribeiro, M.1    Rosenstock, T.R.2    Oliveira, A.M.3    Oliveira, C.R.4    Rego, A.C.5
  • 18
    • 84883188942 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 abrogates microglial oxidative stress and TNF-β responses to spreading depression
    • Grinberg, Y. Y., Dibbern, M. E., Levasseur, V. A., and Kraig, R. P. (2013) Insulin-like growth factor-1 abrogates microglial oxidative stress and TNF-β responses to spreading depression. J. Neurochem. 126, 662-672
    • (2013) J. Neurochem. , vol.126 , pp. 662-672
    • Grinberg, Y.Y.1    Dibbern, M.E.2    Levasseur, V.A.3    Kraig, R.P.4
  • 19
    • 65249096594 scopus 로고    scopus 로고
    • Insulin-like growth factor I: A potential neuroprotective compound for the treatment of acute ischemic stroke?
    • Kooijman, R., Sarre, S., Michotte, Y., and De Keyser, J. (2009) Insulin-like growth factor I: a potential neuroprotective compound for the treatment of acute ischemic stroke? Stroke 40, e83-88
    • (2009) Stroke , vol.40 , pp. e83-88
    • Kooijman, R.1    Sarre, S.2    Michotte, Y.3    De Keyser, J.4
  • 20
    • 37349021747 scopus 로고    scopus 로고
    • Targeting insulin-like growth factor-1 to treat Alzheimer's disease
    • Torres-Aleman, I. (2007) Targeting insulin-like growth factor-1 to treat Alzheimer's disease. Expert Opin. Ther. Targets 11, 1535-1542
    • (2007) Expert Opin. Ther. Targets , vol.11 , pp. 1535-1542
    • Torres-Aleman, I.1
  • 21
    • 84858306047 scopus 로고    scopus 로고
    • Antioxidant and bioenergetic coupling between neurons and astrocytes
    • Fernandez-Fernandez, S., Almeida, A., and Bolaños, J. P. (2012) Antioxidant and bioenergetic coupling between neurons and astrocytes. Biochem. J. 443, 3-11
    • (2012) Biochem. J. , vol.443 , pp. 3-11
    • Fernandez-Fernandez, S.1    Almeida, A.2    Bolaños, J.P.3
  • 22
    • 0042477712 scopus 로고    scopus 로고
    • FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons
    • Gilley, J., Coffer, P. J., and Ham, J. (2003) FOXO transcription factors directly activate bim gene expression and promote apoptosis in sympathetic neurons. J. Cell Biol. 162, 613-622
    • (2003) J. Cell Biol. , vol.162 , pp. 613-622
    • Gilley, J.1    Coffer, P.J.2    Ham, J.3
  • 23
    • 84867019859 scopus 로고    scopus 로고
    • Frataxin deficiency unveils cell-context dependent actions of insulin-like growth factor i on neurons
    • Franco, C., Fernández, S., and Torres-Alemán, I. (2012) Frataxin deficiency unveils cell-context dependent actions of insulin-like growth factor I on neurons. Mol. Neurodegener. 7, 51
    • (2012) Mol. Neurodegener. , vol.7 , pp. 51
    • Franco, C.1    Fernández, S.2    Torres-Alemán, I.3
  • 24
    • 0037376674 scopus 로고    scopus 로고
    • Oxidant signals and oxidative stress
    • Finkel, T. (2003) Oxidant signals and oxidative stress. Curr. Opin. Cell Biol. 15, 247-254
    • (2003) Curr. Opin. Cell Biol. , vol.15 , pp. 247-254
    • Finkel, T.1
  • 25
    • 0346494287 scopus 로고    scopus 로고
    • Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signaling
    • Garcia-Galloway, E., Arango, C., Pons, S., and Torres-Aleman, I. (2003) Glutamate excitotoxicity attenuates insulin-like growth factor-I prosurvival signaling. Mol. Cell. Neurosci. 24, 1027-1037
    • (2003) Mol. Cell. Neurosci. , vol.24 , pp. 1027-1037
    • Garcia-Galloway, E.1    Arango, C.2    Pons, S.3    Torres-Aleman, I.4
  • 26
    • 59849114016 scopus 로고    scopus 로고
    • Studying the subcellular localization and DNA-binding activity of FoxO transcription factors, downstream effectors of PI3K/Akt
    • Essafi, A., Gomes, A. R., Pomeranz, K. M., Zwolinska, A. K., Varshochi, R., McGovern, U. B., and Lam, E. W. (2009) Studying the subcellular localization and DNA-binding activity of FoxO transcription factors, downstream effectors of PI3K/Akt. Methods Mol. Biol. 462, 201-211
    • (2009) Methods Mol. Biol. , vol.462 , pp. 201-211
    • Essafi, A.1    Gomes, A.R.2    Pomeranz, K.M.3    Zwolinska, A.K.4    Varshochi, R.5    McGovern, U.B.6    Lam, E.W.7
  • 27
    • 0033946740 scopus 로고    scopus 로고
    • Phosphorylation of the PTEN tail regulates protein stability and function
    • Vazquez, F., Ramaswamy, S., Nakamura, N., and Sellers, W. R. (2000) Phosphorylation of the PTEN tail regulates protein stability and function. Mol. Cell. Biol. 20, 5010-5018
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5010-5018
    • Vazquez, F.1    Ramaswamy, S.2    Nakamura, N.3    Sellers, W.R.4
  • 28
    • 84963937412 scopus 로고    scopus 로고
    • Kinases, tails and more: Regulation of PTEN function by phosphorylation
    • Fragoso, R., and Barata, J. T. (2015) Kinases, tails and more: regulation of PTEN function by phosphorylation. Methods 77-78, 75-81
    • (2015) Methods , vol.77-78 , pp. 75-81
    • Fragoso, R.1    Barata, J.T.2
  • 30
    • 0033595011 scopus 로고    scopus 로고
    • Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1
    • Biggs, W. H., 3rd, Meisenhelder, J., Hunter, T., Cavenee, W. K., and Arden, K. C. (1999) Protein kinase B/Akt-mediated phosphorylation promotes nuclear exclusion of the winged helix transcription factor FKHR1. Proc. Natl. Acad. Sci. U.S.A. 96, 7421-7426
    • (1999) Proc. Natl. Acad. Sci. U.S.A. , vol.96 , pp. 7421-7426
    • Biggs, W.H.1    Meisenhelder, J.2    Hunter, T.3    Cavenee, W.K.4    Arden, K.C.5
  • 33
    • 0036850972 scopus 로고    scopus 로고
    • Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons
    • Linseman, D. A., Phelps, R. A., Bouchard, R. J., Le, S. S., Laessig, T. A., McClure, M. L., and Heidenreich, K. A. (2002) Insulin-like growth factor-I blocks Bcl-2 interacting mediator of cell death (Bim) induction and intrinsic death signaling in cerebellar granule neurons. J. Neurosci. 22, 9287-9297
    • (2002) J. Neurosci. , vol.22 , pp. 9287-9297
    • Linseman, D.A.1    Phelps, R.A.2    Bouchard, R.J.3    Le, S.S.4    Laessig, T.A.5    McClure, M.L.6    Heidenreich, K.A.7
  • 34
    • 0037169526 scopus 로고    scopus 로고
    • Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation
    • Park, H. S., Kim, M. S., Huh, S. H., Park, J., Chung, J., Kang, S. S., and Choi, E. J. (2002) Akt (protein kinase B) negatively regulates SEK1 by means of protein phosphorylation. J. Biol. Chem. 277, 2573-2578
    • (2002) J. Biol. Chem. , vol.277 , pp. 2573-2578
    • Park, H.S.1    Kim, M.S.2    Huh, S.H.3    Park, J.4    Chung, J.5    Kang, S.S.6    Choi, E.J.7
  • 35
    • 7244243873 scopus 로고    scopus 로고
    • Regulation of Cu/Zn-superoxide dismutase expression via the phosphatidylinositol 3 kinase/Akt pathway and nuclear factor-κB
    • Rojo, A. I., Salinas, M., Martín, D., Perona, R., and Cuadrado, A. (2004) Regulation of Cu/Zn-superoxide dismutase expression via the phosphatidylinositol 3 kinase/Akt pathway and nuclear factor-κB. J. Neurosci. 24, 7324-7334
    • (2004) J. Neurosci. , vol.24 , pp. 7324-7334
    • Rojo, A.I.1    Salinas, M.2    Martín, D.3    Perona, R.4    Cuadrado, A.5
  • 36
    • 45549087514 scopus 로고    scopus 로고
    • Essential roles of the PI3 kinase/Akt pathway in regulating Nrf2-dependent antioxidant functions in the RPE
    • Wang, L., Chen, Y., Sternberg, P., and Cai, J. (2008) Essential roles of the PI3 kinase/Akt pathway in regulating Nrf2-dependent antioxidant functions in the RPE. Invest. Ophthalmol. Vis. Sci. 49, 1671-1678
    • (2008) Invest. Ophthalmol. Vis. Sci. , vol.49 , pp. 1671-1678
    • Wang, L.1    Chen, Y.2    Sternberg, P.3    Cai, J.4
  • 37
    • 79953172583 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinasedependent transactivation of ErbB receptor family: A novel common mechanism for stress-induced IRS-1 serine phosphorylation and insulin resistance
    • Hemi, R., Yochananov, Y., Barhod, E., Kasher-Meron, M., Karasik, A., Tirosh, A., and Kanety, H. (2011) p38 mitogen-activated protein kinasedependent transactivation of ErbB receptor family: a novel common mechanism for stress-induced IRS-1 serine phosphorylation and insulin resistance. Diabetes 60, 1134-1145
    • (2011) Diabetes , vol.60 , pp. 1134-1145
    • Hemi, R.1    Yochananov, Y.2    Barhod, E.3    Kasher-Meron, M.4    Karasik, A.5    Tirosh, A.6    Kanety, H.7
  • 38
    • 79951575665 scopus 로고    scopus 로고
    • Critical role of the transient activation of p38 MAPK in the etiology of skeletal muscle insulin resistance induced by low-level in vitro oxidant stress
    • Diamond-Stanic, M. K., Marchionne, E. M., Teachey, M. K., Durazo, D. E., Kim, J. S., and Henriksen, E. J. (2011) Critical role of the transient activation of p38 MAPK in the etiology of skeletal muscle insulin resistance induced by low-level in vitro oxidant stress. Biochem. Biophys. Res. Commun. 405, 439-444
    • (2011) Biochem. Biophys. Res. Commun. , vol.405 , pp. 439-444
    • Diamond-Stanic, M.K.1    Marchionne, E.M.2    Teachey, M.K.3    Durazo, D.E.4    Kim, J.S.5    Henriksen, E.J.6
  • 40
    • 0037341276 scopus 로고    scopus 로고
    • Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: Potential role of p38 in the downregulation of GLUT4 expression
    • Carlson, C. J., Koterski, S., Sciotti, R. J., Poccard, G. B., and Rondinone, C. M. (2003) Enhanced basal activation of mitogen-activated protein kinases in adipocytes from type 2 diabetes: potential role of p38 in the downregulation of GLUT4 expression. Diabetes 52, 634-641
    • (2003) Diabetes , vol.52 , pp. 634-641
    • Carlson, C.J.1    Koterski, S.2    Sciotti, R.J.3    Poccard, G.B.4    Rondinone, C.M.5
  • 41
    • 84884268759 scopus 로고    scopus 로고
    • Roles of p38-MAPK in insulin resistant heart: Evidence from bench to future bedside application
    • Kumphune, S., Chattipakorn, S., and Chattipakorn, N. (2013) Roles of p38-MAPK in insulin resistant heart: evidence from bench to future bedside application. Curr. Pharm. Des. 19, 5742-5754
    • (2013) Curr. Pharm. Des. , vol.19 , pp. 5742-5754
    • Kumphune, S.1    Chattipakorn, S.2    Chattipakorn, N.3
  • 42
    • 84891685859 scopus 로고    scopus 로고
    • Myocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38α MAPK during insulin resistance
    • Qi, Y., Xu, Z., Zhu, Q., Thomas, C., Kumar, R., Feng, H., Dostal, D. E., White, M. F., Baker, K. M., and Guo, S. (2013) Myocardial loss of IRS1 and IRS2 causes heart failure and is controlled by p38α MAPK during insulin resistance. Diabetes 62, 3887-3900
    • (2013) Diabetes , vol.62 , pp. 3887-3900
    • Qi, Y.1    Xu, Z.2    Zhu, Q.3    Thomas, C.4    Kumar, R.5    Feng, H.6    Dostal, D.E.7    White, M.F.8    Baker, K.M.9    Guo, S.10
  • 44
    • 5644301067 scopus 로고    scopus 로고
    • Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-β induction of p38 and p42/p44 mitogen-activated protein kinases
    • Hernandez, R., Teruel, T., de Alvaro, C., and Lorenzo, M. (2004) Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-β induction of p38 and p42/p44 mitogen-activated protein kinases. Diabetologia 47, 1615-1624
    • (2004) Diabetologia , vol.47 , pp. 1615-1624
    • Hernandez, R.1    Teruel, T.2    De Alvaro, C.3    Lorenzo, M.4
  • 45
    • 28844461131 scopus 로고    scopus 로고
    • Proposed mechanisms for the induction of insulin resistance by oxidative stress
    • Bloch-Damti, A., and Bashan, N. (2005) Proposed mechanisms for the induction of insulin resistance by oxidative stress. Antioxid. Redox Signal. 7, 1553-1567
    • (2005) Antioxid. Redox Signal. , vol.7 , pp. 1553-1567
    • Bloch-Damti, A.1    Bashan, N.2
  • 46
    • 79961207609 scopus 로고    scopus 로고
    • P38beta MAPK affords cytoprotection against oxidative stress-induced astrocyte apoptosis via induction of αb-crystallin and its anti-apoptotic function
    • Shin, J. H., Jeong, J. Y., Jin, Y., Kim, I. D., and Lee, J. K. (2011) p38beta MAPK affords cytoprotection against oxidative stress-induced astrocyte apoptosis via induction of αB-crystallin and its anti-apoptotic function. Neurosci. Lett. 501, 132-137
    • (2011) Neurosci. Lett. , vol.501 , pp. 132-137
    • Shin, J.H.1    Jeong, J.Y.2    Jin, Y.3    Kim, I.D.4    Lee, J.K.5
  • 47
    • 0038363324 scopus 로고    scopus 로고
    • P38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun the determinant roles of the isoforms in the p38 MAPK signal specificity
    • Pramanik, R., Qi, X., Borowicz, S., Choubey, D., Schultz, R. M., Han, J., and Chen, G. (2003) p38 isoforms have opposite effects on AP-1-dependent transcription through regulation of c-Jun. The determinant roles of the isoforms in the p38 MAPK signal specificity. J. Biol. Chem. 278, 4831-4839
    • (2003) J. Biol. Chem. , vol.278 , pp. 4831-4839
    • Pramanik, R.1    Qi, X.2    Borowicz, S.3    Choubey, D.4    Schultz, R.M.5    Han, J.6    Chen, G.7
  • 48
    • 44449108011 scopus 로고    scopus 로고
    • MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: Opposite roles of p38α and p38δ
    • Zhou, X., Ferraris, J. D., Dmitrieva, N. I., Liu, Y., and Burg, M. B. (2008) MKP-1 inhibits high NaCl-induced activation of p38 but does not inhibit the activation of TonEBP/OREBP: opposite roles of p38α and p38δ. Proc. Natl. Acad. Sci. U.S.A. 105, 5620-5625
    • (2008) Proc. Natl. Acad. Sci. U.S.A. , vol.105 , pp. 5620-5625
    • Zhou, X.1    Ferraris, J.D.2    Dmitrieva, N.I.3    Liu, Y.4    Burg, M.B.5
  • 49
    • 77955059513 scopus 로고    scopus 로고
    • Mechanisms and functions of p38 MAPK signalling
    • Cuadrado, A., and Nebreda, A. R. (2010) Mechanisms and functions of p38 MAPK signalling. Biochem. J. 429, 403-417
    • (2010) Biochem. J. , vol.429 , pp. 403-417
    • Cuadrado, A.1    Nebreda, A.R.2
  • 51
    • 0037107552 scopus 로고    scopus 로고
    • Protein kinase CK2: A challenge to canons
    • Pinna, L. A. (2002) Protein kinase CK2: a challenge to canons. J. Cell Sci. 115, 3873-3878
    • (2002) J. Cell Sci. , vol.115 , pp. 3873-3878
    • Pinna, L.A.1
  • 52
    • 0036568813 scopus 로고    scopus 로고
    • Joining the cell survival squad: An emerging role for protein kinase CK2
    • Ahmed, K., Gerber, D. A., and Cochet, C. (2002) Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol. 12, 226-230
    • (2002) Trends Cell Biol. , vol.12 , pp. 226-230
    • Ahmed, K.1    Gerber, D.A.2    Cochet, C.3
  • 54
    • 41949087122 scopus 로고    scopus 로고
    • Modulation by insulin-like growth factor i of the phosphatase PTEN in astrocytes
    • Fernández, S., García-García, M., and Torres-Alemán, I. (2008) Modulation by insulin-like growth factor I of the phosphatase PTEN in astrocytes. Biochim. Biophys. Acta 1783, 803-812
    • (2008) Biochim. Biophys. Acta , vol.1783 , pp. 803-812
    • Fernández, S.1    García-García, M.2    Torres-Alemán, I.3
  • 55
    • 4043063694 scopus 로고    scopus 로고
    • Stimulation of nerve growth factor expression in astrocytes by peroxynitrite
    • Vargas, M. R., Pehar, M., Cassina, P., Estévez, A. G., Beckman, J. S., and Barbeito, L. (2004) Stimulation of nerve growth factor expression in astrocytes by peroxynitrite. In Vivo 18, 269-274
    • (2004) Vivo , vol.18 , pp. 269-274
    • Vargas, M.R.1    Pehar, M.2    Cassina, P.3    Estévez, A.G.4    Beckman, J.S.5    Barbeito, L.6
  • 56
    • 0033230119 scopus 로고    scopus 로고
    • Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species
    • Tanaka, J., Toku, K., Zhang, B., Ishihara, K., Sakanaka, M., and Maeda, N. (1999) Astrocytes prevent neuronal death induced by reactive oxygen and nitrogen species. Glia 28, 85-96
    • (1999) Glia , vol.28 , pp. 85-96
    • Tanaka, J.1    Toku, K.2    Zhang, B.3    Ishihara, K.4    Sakanaka, M.5    Maeda, N.6
  • 58
    • 0642303103 scopus 로고    scopus 로고
    • Transcription of stem cell factor (SCF) is potentiated by glucocorticoids and interleukin-1beta through concerted regulation of a GRE-like and an NF-κB response element
    • Da Silva, C. A., Heilbock, C., Kassel, O., and Frossard, N. (2003) Transcription of stem cell factor (SCF) is potentiated by glucocorticoids and interleukin-1beta through concerted regulation of a GRE-like and an NF-κB response element. FASEB J. 17, 2334-2336
    • (2003) FASEB J. , vol.17 , pp. 2334-2336
    • Da Silva, C.A.1    Heilbock, C.2    Kassel, O.3    Frossard, N.4
  • 59
    • 51849108509 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF)-1α directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF)
    • Han, Z. B., Ren, H., Zhao, H., Chi, Y., Chen, K., Zhou, B., Liu, Y. J., Zhang, L., Xu, B., Liu, B., Yang, R., and Han, Z. C. (2008) Hypoxia-inducible factor (HIF)-1α directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF). Carcinogenesis 29, 1853-1861
    • (2008) Carcinogenesis , vol.29 , pp. 1853-1861
    • Han, Z.B.1    Ren, H.2    Zhao, H.3    Chi, Y.4    Chen, K.5    Zhou, B.6    Liu, Y.J.7    Zhang, L.8    Xu, B.9    Liu, B.10    Yang, R.11    Han, Z.C.12
  • 61
    • 77953183470 scopus 로고    scopus 로고
    • PTEN inhibition improves muscle regeneration in mice fed a highfat diet
    • Hu, Z., Wang, H., Lee, I. H., Modi, S., Wang, X., Du, J., and Mitch, W. E. (2010) PTEN inhibition improves muscle regeneration in mice fed a highfat diet. Diabetes 59, 1312-1320
    • (2010) Diabetes , vol.59 , pp. 1312-1320
    • Hu, Z.1    Wang, H.2    Lee, I.H.3    Modi, S.4    Wang, X.5    Du, J.6    Mitch, W.E.7
  • 63
    • 77949666259 scopus 로고    scopus 로고
    • Pharmacological inhibition of PTEN limits myocardial infarct size and improves left ventricular function postinfarction
    • Keyes, K. T., Xu, J., Long, B., Zhang, C., Hu, Z., and Ye, Y. (2010) Pharmacological inhibition of PTEN limits myocardial infarct size and improves left ventricular function postinfarction. Am. J. Physiol. Heart Circ. Physiol. 298, H1198-H1208
    • (2010) Am. J. Physiol. Heart Circ. Physiol. , vol.298 , pp. H1198-H1208
    • Keyes, K.T.1    Xu, J.2    Long, B.3    Zhang, C.4    Hu, Z.5    Ye, Y.6
  • 64
    • 84902298753 scopus 로고    scopus 로고
    • PTEN degradation after ischemic stroke: A double-edged sword
    • Li, W., Huang, R., Chen, Z., Yan, L. J., Simpkins, J. W., and Yang, S. H. (2014) PTEN degradation after ischemic stroke: a double-edged sword. Neuroscience 274, 153-161
    • (2014) Neuroscience , vol.274 , pp. 153-161
    • Li, W.1    Huang, R.2    Chen, Z.3    Yan, L.J.4    Simpkins, J.W.5    Yang, S.H.6
  • 65
    • 84872334235 scopus 로고    scopus 로고
    • Delayed administration of a PTEN inhibitor BPV improves functional recovery after experimental stroke
    • Mao, L., Jia, J., Zhou, X., Xiao, Y., Wang, Y., Mao, X., Zhen, X., Guan, Y., Alkayed, N. J., and Cheng, J. (2013) Delayed administration of a PTEN inhibitor BPV improves functional recovery after experimental stroke. Neuroscience 231, 272-281
    • (2013) Neuroscience , vol.231 , pp. 272-281
    • Mao, L.1    Jia, J.2    Zhou, X.3    Xiao, Y.4    Wang, Y.5    Mao, X.6    Zhen, X.7    Guan, Y.8    Alkayed, N.J.9    Cheng, J.10
  • 66
    • 84856904410 scopus 로고    scopus 로고
    • Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration
    • Sperow, M., Berry, R. B., Bayazitov, I. T., Zhu, G., Baker, S. J., and Zakharenko, S. S. (2012) Phosphatase and tensin homologue (PTEN) regulates synaptic plasticity independently of its effect on neuronal morphology and migration. J. Physiol. 590, 777-792
    • (2012) J. Physiol. , vol.590 , pp. 777-792
    • Sperow, M.1    Berry, R.B.2    Bayazitov, I.T.3    Zhu, G.4    Baker, S.J.5    Zakharenko, S.S.6
  • 67
    • 51849130466 scopus 로고    scopus 로고
    • PTEN signaling in brain: Neuropathology and tumorigenesis
    • Endersby, R., and Baker, S. J. (2008) PTEN signaling in brain: neuropathology and tumorigenesis. Oncogene 27, 5416-5430
    • (2008) Oncogene , vol.27 , pp. 5416-5430
    • Endersby, R.1    Baker, S.J.2
  • 68
    • 0037073529 scopus 로고    scopus 로고
    • Increased expression of phosphatase and tensin homolog in reactive astrogliosis following intracerebroventricular kainic acid injection in mouse hippocampus
    • Cho, J., Lee, S. H., Seo, J. H., Kim, H. S., Ahn, J. G., Kim, S. S., Yim, S. V., Song, D. K., and Cho, S. S. (2002) Increased expression of phosphatase and tensin homolog in reactive astrogliosis following intracerebroventricular kainic acid injection in mouse hippocampus. Neurosci. Lett. 334, 131-134
    • (2002) Neurosci. Lett. , vol.334 , pp. 131-134
    • Cho, J.1    Lee, S.H.2    Seo, J.H.3    Kim, H.S.4    Ahn, J.G.5    Kim, S.S.6    Yim, S.V.7    Song, D.K.8    Cho, S.S.9
  • 69
    • 77954480424 scopus 로고    scopus 로고
    • PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons
    • Christie, K. J., Webber, C. A., Martinez, J. A., Singh, B., and Zochodne, D. W. (2010) PTEN inhibition to facilitate intrinsic regenerative outgrowth of adult peripheral axons. J. Neurosci. 30, 9306-9315
    • (2010) J. Neurosci. , vol.30 , pp. 9306-9315
    • Christie, K.J.1    Webber, C.A.2    Martinez, J.A.3    Singh, B.4    Zochodne, D.W.5
  • 70
    • 0027939442 scopus 로고
    • Astrocytes express insulin-like growth factor-I (IGF-I) and its binding protein, IGFBP-2, during demyelination induced by experimental autoimmune encephalomyelitis
    • Liu, X., Yao, D. L., Bondy, C. A., Brenner, M., Hudson, L. D., Zhou, J., and Webster, H. D. (1994) Astrocytes express insulin-like growth factor-I (IGF-I) and its binding protein, IGFBP-2, during demyelination induced by experimental autoimmune encephalomyelitis. Mol. Cell. Neurosci. 5, 418-430
    • (1994) Mol. Cell. Neurosci. , vol.5 , pp. 418-430
    • Liu, X.1    Yao, D.L.2    Bondy, C.A.3    Brenner, M.4    Hudson, L.D.5    Zhou, J.6    Webster, H.D.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.