Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-α induction of p38 and p42/p44 mitogen-activated protein kinases

Diabetologia

Volumn 47, Issue 9, 2004, Pages 1615-1624

  Hernandez, R ^a   Teruel, T ^a   De Alvaro, C ^a   Lorenzo, M ^a  

^a UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

Author keywords

Akt; Glucose uptake; GLUT4 translocation; Insulin; JNK; p38MAPK; p42 p44MAPK; PI 3 kinase; Rosiglitazone; TNF

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 NITROPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; ROSIGLITAZONE; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CELL MEMBRANE; CONTROLLED STUDY; CYTOLYSIS; ENZYME ACTIVITY; ENZYME INDUCTION; ENZYME INHIBITION; FEMALE; GLUCOSE TRANSPORT; IMMUNOBLOTTING; IMMUNOPRECIPITATION; IN VITRO STUDY; INSULIN RESISTANCE; INSULIN SENSITIVITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RAT STRAIN; SIGNAL TRANSDUCTION;

ADIPOCYTES; ADIPOSE TISSUE, BROWN; ANIMALS; CELLS, CULTURED; INSULIN RESISTANCE; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RATS; RATS, WISTAR; THIAZOLIDINEDIONES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 5644301067     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-004-1503-7     Document Type: Article

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