Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma

Nature Genetics

Volumn 48, Issue 2, 2016, Pages 183-188

  Okosun, Jessica ^a   Wolfson, Rachel L ^b,c   Wang, Jun ^a   Araf, Shamzah ^a   Wilkins, Lucy ^a   Castellano, Brian M ^d   Escudero Ibarz, Leire ^e   Al Seraihi, Ahad Fahad ^a   Richter, Julia ^f   Bernhart, Stephan H ^g,h   Efeyan, Alejo ^b,c   Iqbal, Sameena ^a   Matthews, Janet ^a   Clear, Andrew ^a   Guerra Assun''o, José Afonso ^a   Bödör, Csaba ⁱ   Quentmeier, Hilmar ^j   Mansbridge, Christopher ^k   Johnson, Peter ^k   Davies, Andrew ^k   Strefford, Jonathan C ^k   Packham, Graham ^k   Barrans, Sharon ^l   Jack, Andrew ^l   Du, Ming Qing ^e   Calaminici, Maria ^a   Lister, T Andrew ^a   Auer, Rebecca ^a   Montoto, Silvia ^a   Gribben, John G ^a   Siebert, Reiner ^f   Chelala, Claude ^a   Zoncu, Roberto ^d   Sabatini, David M ^b,c,m,n   Fitzgibbon, Jude ^a   more..

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^f UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^g LIFE Research Center of Civilization Diseases   (Germany)

^h UNIVERSITY OF LEIPZIG   (Germany)

ⁱ SEMMELWEIS UNIVERSITY   (Hungary)

^j LEIBNIZ INSTITUTE DSMZ GERMAN COLLECTION OF MICROORGANISMS AND CELL CULTURES   (Germany)

^k UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^l ST JAMES S INSTITUTE OF ONCOLOGY   (United Kingdom)

^m KOCH INSTITUTE FOR INTEGRATIVE CANCER RESEARCH   (United States)

ⁿ BROAD INSTITUTE OF MIT AND HARVARD   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATE; AMINO ACID; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; MEMBRANE PROTEIN; RRAGC PROTEIN; UNCLASSIFIED DRUG; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MONOMERIC GUANINE NUCLEOTIDE BINDING PROTEIN; MULTIPROTEIN COMPLEX; RRAGC PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE;

ARTICLE; BINDING AFFINITY; CANCER PATIENT; CLONE; DISEASE COURSE; EXOME; FOLLICULAR LYMPHOMA; GENE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SEQUENCE ANALYSIS; SOMATIC MUTATION; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; GENETICS; MOLECULAR GENETICS; MUTATION; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; ANIMALS; HUMANS; LYMPHOMA, FOLLICULAR; MOLECULAR SEQUENCE DATA; MONOMERIC GTP-BINDING PROTEINS; MULTIPROTEIN COMPLEXES; MUTATION; SEQUENCE HOMOLOGY, AMINO ACID; TOR SERINE-THREONINE KINASES;

EID: 84956702125     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3473     Document Type: Article

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