메뉴 건너뛰기




Volumn 126, Issue 1, 2016, Pages 389-401

Progesterone receptor membrane component-1 regulates hepcidin biosynthesis

Author keywords

[No Author keywords available]

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 6; CHORIONIC GONADOTROPIN; CYCLIC AMP DEPENDENT PROTEIN KINASE; DEXAMETHASONE; EPITIOSTANOL; ESTROGEN; FERROPORTIN; HEPCIDIN; HEPCIDIN INDUCING STEROID; INTERLEUKIN 6; JANUS KINASE; MIFEPRISTONE; NEUTRALIZING ANTIBODY; PHOSPHATIDYLINOSITOL 3 KINASE; PROGESTERONE; PROGESTERONE RECEPTOR; PROGESTERONE RECEPTOR MEMBRANE COMPONENT 1; PROTEIN KINASE C; SMAD1 PROTEIN; STAT3 PROTEIN; STEROID; STEROID HORMONE; TESTOSTERONE; UNCLASSIFIED DRUG; WORTMANNIN; ANDROSTANE DERIVATIVE; CATION TRANSPORT PROTEIN; MEMBRANE PROTEIN; METAL TRANSPORTING PROTEIN 1; PGRMC1 PROTEIN, HUMAN;

EID: 84956666572     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI83831     Document Type: Article
Times cited : (81)

References (64)
  • 1
    • 84878597463 scopus 로고    scopus 로고
    • Iron regulation by hepcidin
    • Zhao N, Zhang AS, Enns CA. Iron regulation by hepcidin. J Clin Invest. 2013;123(6):2337-2343.
    • (2013) J Clin Invest. , vol.123 , Issue.6 , pp. 2337-2343
    • Zhao, N.1    Zhang, A.S.2    Enns, C.A.3
  • 2
    • 84860574815 scopus 로고    scopus 로고
    • Iron sensing and signalling
    • Evstatiev R, Gasche C. Iron sensing and signalling. Gut. 2012;61(6):933-952.
    • (2012) Gut. , vol.61 , Issue.6 , pp. 933-952
    • Evstatiev, R.1    Gasche, C.2
  • 3
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • Nemeth E, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306(5704):2090-2093.
    • (2004) Science. , vol.306 , Issue.5704 , pp. 2090-2093
    • Nemeth, E.1
  • 4
    • 84903578007 scopus 로고    scopus 로고
    • Identification of erythroferrone as an erythroid regulator of iron metabolism
    • Kautz L, Jung G, Valore EV, Rivella S, Nemeth E, Ganz T. Identification of erythroferrone as an erythroid regulator of iron metabolism. Nat Genet. 2014;46(7):678-684.
    • (2014) Nat Genet. , vol.46 , Issue.7 , pp. 678-684
    • Kautz, L.1    Jung, G.2    Valore, E.V.3    Rivella, S.4    Nemeth, E.5    Ganz, T.6
  • 5
    • 63449103712 scopus 로고    scopus 로고
    • BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
    • Andriopoulos B Jr, et al. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet. 2009;41(4):482-487.
    • (2009) Nat Genet. , vol.41 , Issue.4 , pp. 482-487
    • Andriopoulos, B.1
  • 6
    • 33646370235 scopus 로고    scopus 로고
    • Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
    • Babitt JL, et al. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet. 2006;38(5):531-539.
    • (2006) Nat Genet. , vol.38 , Issue.5 , pp. 531-539
    • Babitt, J.L.1
  • 8
    • 2342510407 scopus 로고    scopus 로고
    • IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
    • Nemeth E, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113(9):1271-1276.
    • (2004) J Clin Invest. , vol.113 , Issue.9 , pp. 1271-1276
    • Nemeth, E.1
  • 10
    • 33751175421 scopus 로고    scopus 로고
    • Interleukin-6 induces hepcidin expression through STAT3
    • Wrighting DM, Andrews NC. Interleukin-6 induces hepcidin expression through STAT3. Blood. 2006;108(9):3204-3209.
    • (2006) Blood. , vol.108 , Issue.9 , pp. 3204-3209
    • Wrighting, D.M.1    Andrews, N.C.2
  • 11
    • 84883684492 scopus 로고    scopus 로고
    • Transfusion suppresses erythropoiesis and increases hepcidin in adult patients with β-thalassemia major: A longitudinal study
    • Pasricha SR, Frazer DM, Bowden DK, Anderson GJ. Transfusion suppresses erythropoiesis and increases hepcidin in adult patients with β-thalassemia major: A longitudinal study. Blood. 2013;122(1):124-133.
    • (2013) Blood. , vol.122 , Issue.1 , pp. 124-133
    • Pasricha, S.R.1    Frazer, D.M.2    Bowden, D.K.3    Anderson, G.J.4
  • 12
    • 34249658982 scopus 로고    scopus 로고
    • Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin
    • Gardenghi S, et al. Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin. Blood. 2007;109(11):5027-5035.
    • (2007) Blood. , vol.109 , Issue.11 , pp. 5027-5035
    • Gardenghi, S.1
  • 13
    • 77955906218 scopus 로고    scopus 로고
    • How i treat hemochromatosis
    • Adams PC, Barton JC. How I treat hemochromatosis. Blood. 2010;116(3):317-325.
    • (2010) Blood. , vol.116 , Issue.3 , pp. 317-325
    • Adams, P.C.1    Barton, J.C.2
  • 14
    • 20844460608 scopus 로고    scopus 로고
    • Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine
    • Borgna-Pignatti C, et al. Survival and complications in patients with thalassemia major treated with transfusion and deferoxamine. Haematologica. 2004;89(10):1187-1193.
    • (2004) Haematologica. , vol.89 , Issue.10 , pp. 1187-1193
    • Borgna-Pignatti, C.1
  • 16
    • 84055190801 scopus 로고    scopus 로고
    • Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload
    • Preza GC, et al. Minihepcidins are rationally designed small peptides that mimic hepcidin activity in mice and may be useful for the treatment of iron overload. J Clin Invest. 2011;121(12):4880-4888.
    • (2011) J Clin Invest. , vol.121 , Issue.12 , pp. 4880-4888
    • Preza, G.C.1
  • 17
    • 84861525631 scopus 로고    scopus 로고
    • Deletion of TMPRSS6 attenuates the phenotype in a mouse model of beta-thalassemia
    • Nai A, et al. Deletion of TMPRSS6 attenuates the phenotype in a mouse model of beta-thalassemia. Blood. 2012;119(21):5021-5029.
    • (2012) Blood. , vol.119 , Issue.21 , pp. 5021-5029
    • Nai, A.1
  • 18
    • 84868545645 scopus 로고    scopus 로고
    • Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis
    • Ramos E, et al. Minihepcidins prevent iron overload in a hepcidin-deficient mouse model of severe hemochromatosis. Blood. 2012;120(18):3829-3836.
    • (2012) Blood. , vol.120 , Issue.18 , pp. 3829-3836
    • Ramos, E.1
  • 19
    • 84874066920 scopus 로고    scopus 로고
    • An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia
    • Schmidt PJ, et al. An RNAi therapeutic targeting Tmprss6 decreases iron overload in Hfe(-/-) mice and ameliorates anemia and iron overload in murine β-thalassemia intermedia. Blood. 2013;121(7):1200-1208.
    • (2013) Blood. , vol.121 , Issue.7 , pp. 1200-1208
    • Schmidt, P.J.1
  • 20
    • 0037085441 scopus 로고    scopus 로고
    • Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter
    • Korchynskyi O, ten Dijke P. Identification and functional characterization of distinct critically important bone morphogenetic protein-specific response elements in the Id1 promoter. J Biol Chem. 2002;277(7):4883-4891.
    • (2002) J Biol Chem. , vol.277 , Issue.7 , pp. 4883-4891
    • Korchynskyi, O.1    Ten Dijke, P.2
  • 21
    • 67349204418 scopus 로고    scopus 로고
    • Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/ SMAD
    • Casanovas G, Mleczko-Sanecka K, Altamura S, Hentze MW, Muckenthaler MU. Bone morphogenetic protein (BMP)-responsive elements located in the proximal and distal hepcidin promoter are critical for its response to HJV/BMP/ SMAD. J Mol Med (Berl). 2009;87(5):471-480.
    • (2009) J Mol Med (Berl). , vol.87 , Issue.5 , pp. 471-480
    • Casanovas, G.1    Mleczko-Sanecka, K.2    Altamura, S.3    Hentze, M.W.4    Muckenthaler, M.U.5
  • 22
    • 37249010753 scopus 로고    scopus 로고
    • Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
    • Yu PB, et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 2008;4(1):33-41.
    • (2008) Nat Chem Biol. , vol.4 , Issue.1 , pp. 33-41
    • Yu, P.B.1
  • 23
    • 4143068028 scopus 로고    scopus 로고
    • The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo
    • Zhang K, Chow PK. The effect of megestrol acetate on growth of HepG2 cells in vitro and in vivo. Clin Cancer Res. 2004;10(15):5226-5232.
    • (2004) Clin Cancer Res. , vol.10 , Issue.15 , pp. 5226-5232
    • Zhang, K.1    Chow, P.K.2
  • 24
    • 34547668765 scopus 로고    scopus 로고
    • Progesterone receptor membrane component 1: An integrative review
    • Cahill MA. Progesterone receptor membrane component 1: an integrative review. J Steroid Biochem Mol Biol. 2007;105(1-5):16-36.
    • (2007) J Steroid Biochem Mol Biol. , vol.105 , Issue.1-5 , pp. 16-36
    • Cahill, M.A.1
  • 25
    • 57749085501 scopus 로고    scopus 로고
    • PGRMC1 (progesterone receptor membrane component 1): A targetable protein with multiple functions in steroid signaling, P450 activation and drug binding
    • Rohe HJ, Ahmed IS, Twist KE, Craven RJ. PGRMC1 (progesterone receptor membrane component 1): A targetable protein with multiple functions in steroid signaling, P450 activation and drug binding. Pharmacol Ther. 2009;121(1):14-19.
    • (2009) Pharmacol Ther. , vol.121 , Issue.1 , pp. 14-19
    • Rohe, H.J.1    Ahmed, I.S.2    Twist, K.E.3    Craven, R.J.4
  • 26
    • 33845483366 scopus 로고    scopus 로고
    • Progesterone regulation of human granulosa/ luteal cell viability by an RU486-independent mechanism
    • Engmann L, Losel R, Wehling M, Peluso JJ. Progesterone regulation of human granulosa/ luteal cell viability by an RU486-independent mechanism. J Clin Endocrinol Metab. 2006;91(12):4962-4968.
    • (2006) J Clin Endocrinol Metab. , vol.91 , Issue.12 , pp. 4962-4968
    • Engmann, L.1    Losel, R.2    Wehling, M.3    Peluso, J.J.4
  • 27
    • 77956245653 scopus 로고    scopus 로고
    • Interruption of cenph causes mitotic failure and embryonic death, and its haploinsufficiency suppresses cancer in zebrafish
    • Zhao X, et al. Interruption of cenph causes mitotic failure and embryonic death, and its haploinsufficiency suppresses cancer in zebrafish. J Biol Chem. 2010;285(36):27924-27934.
    • (2010) J Biol Chem. , vol.285 , Issue.36 , pp. 27924-27934
    • Zhao, X.1
  • 28
    • 34447503431 scopus 로고    scopus 로고
    • Membrane-initiated effects of progesterone on calcium dependent signaling and activation of VEGF gene expression in retinal glial cells
    • Swiatek-De Lange M, et al. Membrane-initiated effects of progesterone on calcium dependent signaling and activation of VEGF gene expression in retinal glial cells. Glia. 2007;55(10):1061-1073.
    • (2007) Glia. , vol.55 , Issue.10 , pp. 1061-1073
    • Swiatek-De Lange, M.1
  • 29
    • 84910636973 scopus 로고    scopus 로고
    • Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic beta cells
    • Zhang M, et al. Progesterone receptor membrane component 1 is a functional part of the glucagon-like peptide-1 (GLP-1) receptor complex in pancreatic beta cells. Mol Cell Proteomics. 2014;13(11):3049-3062.
    • (2014) Mol Cell Proteomics. , vol.13 , Issue.11 , pp. 3049-3062
    • Zhang, M.1
  • 30
    • 0030029143 scopus 로고    scopus 로고
    • Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor
    • Hanke JH, et al. Discovery of a novel, potent, and Src family-selective tyrosine kinase inhibitor. Study of Lck-and FynT-dependent T cell activation. J Biol Chem. 1996;271(2):695-701.
    • (1996) Study of Lck-and FynT-dependent T Cell Activation. J Biol Chem. , vol.271 , Issue.2 , pp. 695-701
    • Hanke, J.H.1
  • 31
    • 34249774266 scopus 로고    scopus 로고
    • PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia
    • Hou XY, Liu Y, Zhang GY. PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia. Neurosci Lett. 2007;420(3):235-239.
    • (2007) Neurosci Lett. , vol.420 , Issue.3 , pp. 235-239
    • Hou, X.Y.1    Liu, Y.2    Zhang, G.Y.3
  • 32
    • 84883144236 scopus 로고    scopus 로고
    • The soluble guanylate cyclase activator BAY 58-2667 protects against morbidity and mortality in endotoxic shock by recoupling organ systems
    • Vandendriessche B, et al. The soluble guanylate cyclase activator BAY 58-2667 protects against morbidity and mortality in endotoxic shock by recoupling organ systems. PLoS One. 2013;8(8):e72155.
    • (2013) PLoS One. , vol.8 , Issue.8 , pp. e72155
    • Vandendriessche, B.1
  • 34
    • 84907764334 scopus 로고    scopus 로고
    • Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone
    • Beggs LA, et al. Testosterone alters iron metabolism and stimulates red blood cell production independently of dihydrotestosterone. Am J Physiol Endocrinol Metab. 2014;307(5):E456-E461.
    • (2014) Am J Physiol Endocrinol Metab. , vol.307 , Issue.5 , pp. E456-E461
    • Beggs, L.A.1
  • 35
    • 84868556656 scopus 로고    scopus 로고
    • Hepcidin demonstrates a biphasic association with anemia in acute Plasmodium falciparum malaria
    • Casals-Pascual C, et al. Hepcidin demonstrates a biphasic association with anemia in acute Plasmodium falciparum malaria. Haematologica. 2012;97(11):1695-1698.
    • (2012) Haematologica. , vol.97 , Issue.11 , pp. 1695-1698
    • Casals-Pascual, C.1
  • 36
    • 84874655521 scopus 로고    scopus 로고
    • Obesity during pregnancy and fetal iron status: Is Hepcidin the link?
    • Dao MC, Sen S, Iyer C, Klebenov D, Meydani SN. Obesity during pregnancy and fetal iron status: is Hepcidin the link? J Perinatol. 2013;33(3):177-181.
    • (2013) J Perinatol. , vol.33 , Issue.3 , pp. 177-181
    • Dao, M.C.1    Sen, S.2    Iyer, C.3    Klebenov, D.4    Meydani, S.N.5
  • 37
    • 84856072239 scopus 로고    scopus 로고
    • Regulation of hepcidin expression at high altitude
    • Talbot NP, et al. Regulation of hepcidin expression at high altitude. Blood. 2012;119(3):857-860.
    • (2012) Blood. , vol.119 , Issue.3 , pp. 857-860
    • Talbot, N.P.1
  • 38
    • 79955980950 scopus 로고    scopus 로고
    • Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation
    • Steinbicker AU, et al. Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation. Blood. 2011;117(18):4915-4923.
    • (2011) Blood. , vol.117 , Issue.18 , pp. 4915-4923
    • Steinbicker, A.U.1
  • 39
    • 84862792124 scopus 로고    scopus 로고
    • Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation
    • Sun CC, Vaja V, Babitt JL, Lin HY. Targeting the hepcidin-ferroportin axis to develop new treatment strategies for anemia of chronic disease and anemia of inflammation. Am J Hematol. 2012;87(4):392-400.
    • (2012) Am J Hematol. , vol.87 , Issue.4 , pp. 392-400
    • Sun, C.C.1    Vaja, V.2    Babitt, J.L.3    Lin, H.Y.4
  • 40
    • 34447137331 scopus 로고    scopus 로고
    • Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
    • Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, Lin HY. Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest. 2007;117(7):1933-1939.
    • (2007) J Clin Invest. , vol.117 , Issue.7 , pp. 1933-1939
    • Babitt, J.L.1    Huang, F.W.2    Xia, Y.3    Sidis, Y.4    Andrews, N.C.5    Lin, H.Y.6
  • 41
    • 0029900104 scopus 로고    scopus 로고
    • Purification and partial sequencing of high-affinity progesterone-binding site(s) from porcine liver membranes
    • Meyer C, Schmid R, Scriba PC, Wehling M. Purification and partial sequencing of high-affinity progesterone-binding site(s) from porcine liver membranes. Eur J Biochem. 1996;239(3):726-731.
    • (1996) Eur J Biochem. , vol.239 , Issue.3 , pp. 726-731
    • Meyer, C.1    Schmid, R.2    Scriba, P.C.3    Wehling, M.4
  • 42
    • 28044468385 scopus 로고    scopus 로고
    • Molecular identification of adrenal inner zone antigen as a heme-binding protein
    • Min L, et al. Molecular identification of adrenal inner zone antigen as a heme-binding protein. FEBS J. 2005;272(22):5832-5843.
    • (2005) FEBS J. , vol.272 , Issue.22 , pp. 5832-5843
    • Min, L.1
  • 43
    • 84898934319 scopus 로고    scopus 로고
    • Non-canonical progesterone signaling in granulosa cell function
    • Peluso JJ, Pru JK. Non-canonical progesterone signaling in granulosa cell function. Reproduction. 2014;147(5):R169-R178.
    • (2014) Reproduction. , vol.147 , Issue.5 , pp. R169-R178
    • Peluso, J.J.1    Pru, J.K.2
  • 44
    • 43249120558 scopus 로고    scopus 로고
    • Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1
    • Peluso JJ, Liu X, Saunders MM, Claffey KP, Phoenix K. Regulation of ovarian cancer cell viability and sensitivity to cisplatin by progesterone receptor membrane component-1. J Clin Endocrinol Metab. 2008;93(5):1592-1599.
    • (2008) J Clin Endocrinol Metab. , vol.93 , Issue.5 , pp. 1592-1599
    • Peluso, J.J.1    Liu, X.2    Saunders, M.M.3    Claffey, K.P.4    Phoenix, K.5
  • 45
    • 33646806787 scopus 로고    scopus 로고
    • Progesterone membrane receptor component 1 expression in the immature rat ovary and its role in mediating progesterone's antiapoptotic action
    • Peluso JJ, Pappalardo A, Losel R, Wehling M. Progesterone membrane receptor component 1 expression in the immature rat ovary and its role in mediating progesterone's antiapoptotic action. Endocrinology. 2006;147(6):3133-3140.
    • (2006) Endocrinology. , vol.147 , Issue.6 , pp. 3133-3140
    • Peluso, J.J.1    Pappalardo, A.2    Losel, R.3    Wehling, M.4
  • 46
    • 33846635481 scopus 로고    scopus 로고
    • Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes
    • Hughes AL, et al. Dap1/PGRMC1 binds and regulates cytochrome P450 enzymes. Cell Metab. 2007;5(2):143-149.
    • (2007) Cell Metab. , vol.5 , Issue.2 , pp. 143-149
    • Hughes, A.L.1
  • 47
    • 14044252188 scopus 로고    scopus 로고
    • Dap1p, a heme-binding protein that regulates the cytochrome P450 protein Erg11p/Cyp51p in Saccharomyces cerevisiae
    • Mallory JC, et al. Dap1p, a heme-binding protein that regulates the cytochrome P450 protein Erg11p/Cyp51p in Saccharomyces cerevisiae. Mol Cell Biol. 2005;25(5):1669-1679.
    • (2005) Mol Cell Biol. , vol.25 , Issue.5 , pp. 1669-1679
    • Mallory, J.C.1
  • 48
    • 37549014195 scopus 로고    scopus 로고
    • Regulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51
    • Craven RJ, Mallory JC, Hand RA. Regulation of iron homeostasis mediated by the heme-binding protein Dap1 (damage resistance protein 1) via the P450 protein Erg11/Cyp51. J Biol Chem. 2007;282(50):36543-36551.
    • (2007) J Biol Chem. , vol.282 , Issue.50 , pp. 36543-36551
    • Craven, R.J.1    Mallory, J.C.2    Hand, R.A.3
  • 49
    • 84863981673 scopus 로고    scopus 로고
    • Evidence for a genomic mechanism of action for progesterone receptor membrane component-1
    • Peluso JJ, DeCerbo J, Lodde V. Evidence for a genomic mechanism of action for progesterone receptor membrane component-1. Steroids. 2012;77(10):1007-1012.
    • (2012) Steroids. , vol.77 , Issue.10 , pp. 1007-1012
    • Peluso, J.J.1    DeCerbo, J.2    Lodde, V.3
  • 50
    • 79960674973 scopus 로고    scopus 로고
    • Regulation of TMPRSS6 by BMP6 and iron in human cells and mice
    • Meynard D, et al. Regulation of TMPRSS6 by BMP6 and iron in human cells and mice. Blood. 2011;118(3):747-756.
    • (2011) Blood. , vol.118 , Issue.3 , pp. 747-756
    • Meynard, D.1
  • 51
    • 84868193427 scopus 로고    scopus 로고
    • Estrogen regulates iron homeostasis through governing hepatic hepcidin expression via an estrogen response element
    • Hou Y, et al. Estrogen regulates iron homeostasis through governing hepatic hepcidin expression via an estrogen response element. Gene. 2012;511(2):398-403.
    • (2012) Gene. , vol.511 , Issue.2 , pp. 398-403
    • Hou, Y.1
  • 52
    • 84863827034 scopus 로고    scopus 로고
    • Estrogen regulates hepcidin expression via GPR30-BMP6-dependent signaling in hepatocytes
    • Ikeda Y, et al. Estrogen regulates hepcidin expression via GPR30-BMP6-dependent signaling in hepatocytes. PLoS One. 2012;7(7):e40465.
    • (2012) PLoS One. , vol.7 , Issue.7 , pp. e40465
    • Ikeda, Y.1
  • 53
    • 84862736353 scopus 로고    scopus 로고
    • 17beta-Estradiol inhibits iron hormone hepcidin through an estrogen responsive element half-site
    • Yang Q, Jian J, Katz S, Abramson SB, Huang X. 17beta-Estradiol inhibits iron hormone hepcidin through an estrogen responsive element half-site. Endocrinology. 2012;153(7):3170-3178.
    • (2012) Endocrinology. , vol.153 , Issue.7 , pp. 3170-3178
    • Yang, Q.1    Jian, J.2    Katz, S.3    Abramson, S.B.4    Huang, X.5
  • 54
    • 84878914192 scopus 로고    scopus 로고
    • Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells
    • Guo W, et al. Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells. Aging Cell. 2013;12(2):280-291.
    • (2013) Aging Cell. , vol.12 , Issue.2 , pp. 280-291
    • Guo, W.1
  • 55
    • 84893655780 scopus 로고    scopus 로고
    • Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin
    • Latour C, et al. Testosterone perturbs systemic iron balance through activation of epidermal growth factor receptor signaling in the liver and repression of hepcidin. Hepatology. 2014;59(2):683-694.
    • (2014) Hepatology. , vol.59 , Issue.2 , pp. 683-694
    • Latour, C.1
  • 56
    • 84904344650 scopus 로고    scopus 로고
    • Sex differences in iron status and hepcidin expression in rats
    • Kong WN, et al. Sex differences in iron status and hepcidin expression in rats. Biol Trace Elem Res. 2014;160(2):258-267.
    • (2014) Biol Trace Elem Res. , vol.160 , Issue.2 , pp. 258-267
    • Kong, W.N.1
  • 57
    • 79959517566 scopus 로고    scopus 로고
    • Serum hepcidin: Reference ranges and biochemical correlates in the general population
    • Galesloot TE, et al. Serum hepcidin: reference ranges and biochemical correlates in the general population. Blood. 2011;117(25):e218-e225.
    • (2011) Blood. , vol.117 , Issue.25 , pp. e218-e225
    • Galesloot, T.E.1
  • 60
    • 0034667970 scopus 로고    scopus 로고
    • Using progestins in clinical practice
    • Apgar BS, Greenberg G. Using progestins in clinical practice. Am Fam Physician. 2000;62(8):1839-1846.
    • (2000) Am Fam Physician. , vol.62 , Issue.8 , pp. 1839-1846
    • Apgar, B.S.1    Greenberg, G.2
  • 61
    • 84861967547 scopus 로고    scopus 로고
    • Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome
    • Fleseriu M, et al. Mifepristone, a glucocorticoid receptor antagonist, produces clinical and metabolic benefits in patients with Cushing's syndrome. J Clin Endocrinol Metab. 2012;97(6):2039-2049.
    • (2012) J Clin Endocrinol Metab. , vol.97 , Issue.6 , pp. 2039-2049
    • Fleseriu, M.1
  • 62
    • 76249114963 scopus 로고    scopus 로고
    • Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos
    • Li X, Jia S, Wang S, Wang Y, Meng A. Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos. Blood. 2009;114(27):5464-5472.
    • (2009) Blood. , vol.114 , Issue.27 , pp. 5464-5472
    • Li, X.1    Jia, S.2    Wang, S.3    Wang, Y.4    Meng, A.5
  • 63
    • 63849158505 scopus 로고    scopus 로고
    • Transferrin-A modulates hepcidin expression in zebrafish embryos
    • Fraenkel PG, et al. Transferrin-A modulates hepcidin expression in zebrafish embryos. Blood. 2009;113(12):2843-2850.
    • (2009) Blood. , vol.113 , Issue.12 , pp. 2843-2850
    • Fraenkel, P.G.1
  • 64
    • 84902105343 scopus 로고    scopus 로고
    • The type i BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6
    • Mayeur C, et al. The type I BMP receptor Alk3 is required for the induction of hepatic hepcidin gene expression by interleukin-6. Blood. 2014;123(14):2261-2268.
    • (2014) Blood. , vol.123 , Issue.14 , pp. 2261-2268
    • Mayeur, C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.