Mta3-NuRD complex is a master regulator for initiation of primitive hematopoiesis in vertebrate embryos

Blood

Volumn 114, Issue 27, 2009, Pages 5464-5472

  Li, Xiang ^a   Jia, Shunji ^a   Wang, Shaohe ^a   Wang, Yuemeng ^a   Meng, Anming ^a,b  

^a TSINGHUA UNIVERSITY   (China)

^b INSTITUTE OF ZOOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; ANTIGEN; DEACYLTRANSFERASE; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; METASTASIS ASSOCIATED ANTIGEN 1; NUCLEOSOME REMODELING AND DEACETYLASE; TRANSCRIPTION FACTOR TAL1; TRICHOSTATIN A; UNCLASSIFIED DRUG; VALPROIC ACID; HISTONE DEACETYLASE; HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID; MTA3 PROTEIN, ZEBRAFISH; REPRESSOR PROTEIN; ZEBRAFISH PROTEIN;

ANGIOGENESIS; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CONTROLLED STUDY; DEACETYLATION; EMBRYO; EMBRYO DEVELOPMENT; ENZYME ACTIVITY; GENE; GENE EXPRESSION; HEMATOPOIESIS; IMO2 GENE; MESODERM; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RETICULOSARCOMA; VERTEBRATE; ZEBRA FISH; ACETYLATION; ANIMAL; ANIMAL EMBRYO; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; IN SITU HYBRIDIZATION; METABOLISM; PHYSIOLOGY; PRENATAL DEVELOPMENT; TIME; TRANSGENIC ANIMAL; VASCULARIZATION;

ACETYLATION; ANIMALS; ANIMALS, GENETICALLY MODIFIED; EMBRYO, NONMAMMALIAN; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE KNOCKDOWN TECHNIQUES; HEMATOPOIESIS; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE INHIBITORS; HUMANS; HYDROXAMIC ACIDS; IN SITU HYBRIDIZATION; MI-2 NUCLEOSOME REMODELING AND DEACETYLASE COMPLEX; NEOVASCULARIZATION, PHYSIOLOGIC; REPRESSOR PROTEINS; TIME FACTORS; VALPROIC ACID; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 76249114963     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2009-06-227777     Document Type: Article

References (49)

1. Davidson AJ, Zon LI. The 'definitive' (and 'primitive') guide to zebrafish hematopoiesis. Oncogene. 2004;23(43):7233-7246.
2. de Jong JL, Zon LI. Use of the zebrafish system to study primitive and definitive hematopoiesis. Annu Rev Genet. 2005;39:481-501.
3. Galloway JL, Zon LI. Ontogeny of hematopoiesis: examining the emergence of hematopoietic cells in the vertebrate embryo. Curr Top Dev Biol. 2003;53:139-158.
4. Hsia N, Zon LI. Transcriptional regulation of hematopoietic stem cell development in zebrafish. Exp Hematol. 2005;33(9):1007-1014.
5. Lécuyer E, Hoang T. SCL: from the origin of hematopoiesis to stem cells and leukemia. Exp Hematol. 2004;32(1):11-24.
6. Patterson LJ, Gering M, Patient R. Scl is required for dorsal aorta as well as blood formation in zebrafish embryos. Blood. 2005;105(9):3502-3511.
7. Dooley KA, Davidson AJ, Zon LI. Zebrafish scl functions independently in hematopoietic and endothelial development. Dev Biol. 2005;277(2):522-536.
8. Qian F, Zhen F, Xu J, Huang M, Li W, Wen Z. Distinct functions for different scl isoforms in zebrafish primitive and definitive hematopoiesis. PLoS Biol. 2007;5(5):e132.
9. Gering M, Rodaway AR, Gottgens B, Patient RK, Green AR. The SCL gene specifies haemangioblast development from early mesoderm. EMBO J. 1998;17(14):4029-4045.
10. Gering M, Yamada Y, Rabbitts TH, Patient RK. Lmo2 and Scl/Tal1 convert non-axial mesoderm into haemangioblasts which differentiate into endothelial cells in the absence of Gata1. Development. 2003;130(25):6187-6199.
11. Bowen NJ, Fujita N, Kajita M, Wade PA. Mi-2/NuRD: multiple complexes for many purposes. Biochim Biophys Acta. 2004;1677(1-3):52-57.
12. Denslow SA, Wade PA. The human Mi-2/NuRD complex and gene regulation. Oncogene. 2007;26(37):5433-5438.
13. McDonel P, Costello I, Hendrich B. Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development. Int J Biochem Cell Biol. 2009;41(1):108-116.
14. Toh Y, Nicolson GL. The role of the MTA family and their encoded proteins in human cancers: molecular functions and clinical implications. Clin Exp Metastasis. 2009;26(3):215-227.
15. Siatecka M, Xue L, Bieker JJ. Sumoylation of EKLF promotes transcriptional repression and is involved in inhibition of megakaryopoiesis. Mol Cell Biol. 2007;27(24):8547-8560.
16. Hamlett I, Draper J, Strouboulis J, Iborra F, Porcher C, Vyas P. Characterization of megakaryocyte GATA1-interacting proteins: the corepressor ETO2 and GATA1 interact to regulate terminal megakaryocyte maturation. Blood. 2008;112(7):2738-2749.
17. Hutchins AS, Mullen AC, Lee HW, et al. Gene silencing quantitatively controls the function of a developmental trans-activator. Mol Cell. 2002;10(1):81-91.
18. Fujita N, Jaye DL, Geigerman C, et al. MTA3 and the Mi-2/NuRD complex regulate cell fate during B lymphocyte differentiation. Cell. 2004;119(1):75-86.
19. Cismasiu VB, Adamo K, Gecewicz J, Duque J, Lin Q, Avram D. BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter. Oncogene. 2005;24(45):6753-6764.
20. Williams CJ, Naito T, Arco PG, et al. The chromatin remodeler Mi-2beta is required for CD4 expression and T cell development. Immunity. 2004;20(6):719-733.
21. Hong W, Nakazawa M, Chen YY, et al. FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1. EMBO J. 2005;24(13):2367-2378.
22. Rodriguez P, Bonte E, Krijgsveld J, et al. GATA-1 forms distinct activating and repressive complexes in erythroid cells. EMBO J. 2005;24(13):2354-2366.
23. Harju-Baker S, Costa FC, Fedosyuk H, Neades R, Peterson KR. Silencing of Agamma-globin gene expression during adult definitive erythropoiesis mediated by GATA-1-FOG-1-Mi2 complex binding at the -566 GATA site. Mol Cell Biol. 2008;28(10):3101-3113.
24. Sankaran VG, Menne TF, Xu J, et al. Human fetal hemoglobin expression is regulated by the developmental stage-specific repressor BCL11A. Science. 2008;322(5909):1839-1842.
25. Yoshida T, Hazan I, Zhang J, et al. The role of the chromatin remodeler Mi-2beta in hematopoietic stem cell self-renewal and multilineage differentiation. Genes Dev. 2008;22(9):1174-1189.
26. Shepard JL, Amatruda JF, Stern HM, et al. A zebrafish bmyb mutation causes genome instability and increased cancer susceptibility. Proc Natl Acad Sci U S A. 2005;102(37):13194-13199.
27. Detrich HW III, Kieran MW, Chan FY, et al. Intraembryonic hematopoietic cell migration during vertebrate development. Proc Natl Acad Sci U S A. 1995;92(23):10713-10717.
28. University of Oregon. The Zebrafish Model Organism Database. http://zfin.org. Accessed January 11, 2007.
29. Lieschke GJ, Oates AC, Paw BH, et al. Zebrafish SPI-1 (PU. 1) marks a site of myeloid development independent of primitive erythropoiesis: implications for axial patterning. Dev Biol. 2002;246(2):274-295.
30. Vogeli KM, Jin SW, Martin GR, Stainier DY. A common progenitor for haematopoietic and endothelial lineages in the zebrafish gastrula. Nature. 2006;443(7109):337-339.
31. Robu ME, Larson JD, Nasevicius A, et al. p53 activation by knockdown technologies. PLoS Genet. 2007;3(5):e78.
32. Kimmel CB, Warga RM, Schilling TF. Origin and organization of the zebrafish fate map. Development. 1990;108(4):581-594.
33. Neave B, Holder N, Patient R. A graded response to BMP-4 spatially coordinates patterning of the mesoderm and ectoderm in the zebrafish. Mech Dev. 1997;62(2):183-195.
34. Brown LA, Rodaway AR, Schilling TF, et al. Insights into early vasculogenesis revealed by expression of the ETS-domain transcription factor Fli-1 in wild-type and mutant zebrafish embryos. Mech Dev. 2000;90(2):237-252.
35. Liu F, Walmsley M, Rodaway A, Patient R. Fli1 acts at the top of the transcriptional network driving blood and endothelial development. Curr Biol. 2008;18(16):1234-1240.
36. Warren AJ, Colledge WH, Carlton MB, Evans MJ, Smith AJ, Rabbitts TH. The oncogenic cysteinerich LIM domain protein rbtn2 is essential for erythroid development. Cell. 1994;78(1):45-57.
37. Kamesaki H, Michaud GY, Irving SG, et al. TPAinduced arrest of erythroid differentiation is coupled with downregulation of GATA-1 and upregulation of GATA-2 in an erythroid cell line SAM-1. Blood. 1996;87(3):999-1005.
38. Buck I, Morceau F, Cristofanon S, et al. Tumor necrosis factor alpha inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation. Biochem Pharmacol. 2008;76(10):1229-1239.
39. Zhang H, Singh RR, Talukder AH, Kumar R. Metastatic tumor antigen 3 is a direct corepressor of the Wnt4 pathway. Genes Dev. 2006;20(21):2943-2948.
40. Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS. Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem. 2001;276(39):36734-36741.
41. Göttlicher M, Minucci S, Zhu P, et al. Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J. 2001;20(24):6969-6978.
42. Yildirim E, Zhang Z, Uz T, Chen CQ, Manev R, Manev H. Valproate administration to mice increases histone acetylation and 5-lipoxygenase content in the hippocampus. Neurosci Lett. 2003;345(2):141-143.
43. Gurvich N, Berman MG, Wittner BS, Gentleman RC, Klein PS, Green JB. Association of valproateinduced teratogenesis with histone deacetylase inhibition in vivo. FASEB J. 2005;19(9):1166-1168.
44. Burns CE, Galloway JL, Smith AC, et al. A genetic screen in zebrafish defines a hierarchical network of pathways required for hematopoietic stem cell emergence. Blood. 2009;113(23):5776-5782.
45. Bagheri-Yarmand R, Talukder AH, Wang RA, Vadlamudi RK, Kumar R. Metastasis-associated protein 1 deregulation causes inappropriate mammary gland development and tumorigenesis. Development. 2004;131(14):3469-3479.
46. Matsusue K, Takiguchi S, Toh Y, Kono A. Characterization of mouse metastasis-associated gene 2: genomic structure, nuclear localization signal, and alternative potentials as transcriptional activator and repressor. DNA Cell Biol. 2001;20(10):603-611.
47. Gururaj AE, Singh RR, Rayala SK, et al. MTA1, a transcriptional activator of breast cancer amplified sequence 3. Proc Natl Acad Sci U S A. 2006;103(17):6670-6675.
48. Luo J, Su F, Chen D, Shiloh A, Gu W. Deacetylation of p53 modulates its effect on cell growth and apoptosis. Nature. 2000;408(6810):377-381.
49. Yoo YG, Kong G, Lee MO. Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1. EMBO J. 2006;25(6):1231-1241.