메뉴 건너뛰기




Volumn 64, Issue , 2016, Pages 11-21

Bacteria sensing mechanisms in Drosophila gut: Local and systemic consequences

Author keywords

Bacteria; Drosophila; Intestinal immunity; NF B; Peptidoglycan; PGRPs

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PEPTIDOGLYCAN; PEPTIDOGLYCAN RECOGNITION PROTEIN; CARRIER PROTEIN; PATTERN RECOGNITION RECEPTOR;

EID: 84956464960     PISSN: 0145305X     EISSN: 18790089     Source Type: Journal    
DOI: 10.1016/j.dci.2016.01.001     Document Type: Article
Times cited : (36)

References (134)
  • 1
    • 43249114465 scopus 로고    scopus 로고
    • Positive and negative regulation of the Drosophila immune response
    • Aggarwal, K., Silverman, N., Positive and negative regulation of the Drosophila immune response. BMB Rep. 41 (2008), 267–277.
    • (2008) BMB Rep. , vol.41 , pp. 267-277
    • Aggarwal, K.1    Silverman, N.2
  • 2
    • 84897928013 scopus 로고    scopus 로고
    • Intestinal inflammation and stem cell homeostasis in aging Drosophila melanogaster
    • Ayyaz, A., Jasper, H., Intestinal inflammation and stem cell homeostasis in aging Drosophila melanogaster. Front. Cell. Infect. Microbiol., 3, 2013, 98.
    • (2013) Front. Cell. Infect. Microbiol. , vol.3 , pp. 98
    • Ayyaz, A.1    Jasper, H.2
  • 3
    • 84930160218 scopus 로고    scopus 로고
    • Haemocytes control stem cell activity in the Drosophila intestine
    • Ayyaz, A., Li, H., Jasper, H., Haemocytes control stem cell activity in the Drosophila intestine. Nat. cell Biol. 17 (2015), 736–748.
    • (2015) Nat. cell Biol. , vol.17 , pp. 736-748
    • Ayyaz, A.1    Li, H.2    Jasper, H.3
  • 4
    • 0014598075 scopus 로고
    • The persistence of a microbial flora during postembryogenesis of Drosophila melanogaster
    • Bakula, M., The persistence of a microbial flora during postembryogenesis of Drosophila melanogaster. J. Invertebr. Pathol. 14 (1969), 365–374.
    • (1969) J. Invertebr. Pathol. , vol.14 , pp. 365-374
    • Bakula, M.1
  • 5
    • 79953317939 scopus 로고    scopus 로고
    • The Drosophila peptidoglycan-recognition protein LF interacts with peptidoglycan-recognition protein LC to downregulate the Imd pathway
    • Basbous, N., Coste, F., Leone, P., Vincentelli, R., Royet, J., Kellenberger, C., Roussel, A., The Drosophila peptidoglycan-recognition protein LF interacts with peptidoglycan-recognition protein LC to downregulate the Imd pathway. EMBO Rep. 12 (2011), 327–333.
    • (2011) EMBO Rep. , vol.12 , pp. 327-333
    • Basbous, N.1    Coste, F.2    Leone, P.3    Vincentelli, R.4    Royet, J.5    Kellenberger, C.6    Roussel, A.7
  • 6
    • 9244251126 scopus 로고    scopus 로고
    • Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of gram-positive bacteria
    • Bischoff, V., Vignal, C., Boneca, I.G., Michel, T., Hoffmann, J.A., Royet, J., Function of the drosophila pattern-recognition receptor PGRP-SD in the detection of gram-positive bacteria. Nat. Immunol. 5 (2004), 1175–1180.
    • (2004) Nat. Immunol. , vol.5 , pp. 1175-1180
    • Bischoff, V.1    Vignal, C.2    Boneca, I.G.3    Michel, T.4    Hoffmann, J.A.5    Royet, J.6
  • 7
    • 33645770760 scopus 로고    scopus 로고
    • Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2
    • Bischoff, V., Vignal, C., Duvic, B., Boneca, I.G., Hoffmann, J.A., Royet, J., Downregulation of the Drosophila immune response by peptidoglycan-recognition proteins SC1 and SC2. PLoS Pathog., 2, 2006, e14.
    • (2006) PLoS Pathog. , vol.2 , pp. e14
    • Bischoff, V.1    Vignal, C.2    Duvic, B.3    Boneca, I.G.4    Hoffmann, J.A.5    Royet, J.6
  • 8
    • 80755174406 scopus 로고    scopus 로고
    • Maintaining tissue homeostasis: dynamic control of somatic stem cell activity
    • Biteau, B., Hochmuth, C.E., Jasper, H., Maintaining tissue homeostasis: dynamic control of somatic stem cell activity. Cell Stem Cell 9 (2011), 402–411.
    • (2011) Cell Stem Cell , vol.9 , pp. 402-411
    • Biteau, B.1    Hochmuth, C.E.2    Jasper, H.3
  • 9
    • 84891592625 scopus 로고    scopus 로고
    • Frequent replenishment sustains the beneficial microbiome of Drosophila melanogaster
    • e00860–00813
    • Blum, J.E., Fischer, C.N., Miles, J., Handelsman, J., Frequent replenishment sustains the beneficial microbiome of Drosophila melanogaster. MBio, 4, 2013 e00860–00813.
    • (2013) MBio , vol.4
    • Blum, J.E.1    Fischer, C.N.2    Miles, J.3    Handelsman, J.4
  • 10
    • 84865108178 scopus 로고    scopus 로고
    • Peptidoglycan sensing by the receptor PGRP-LE in the Drosophila gut induces immune responses to infectious bacteria and tolerance to microbiota
    • Bosco-Drayon, V., Poidevin, M., Boneca, I.G., Narbonne-Reveau, K., Royet, J., Charroux, B., Peptidoglycan sensing by the receptor PGRP-LE in the Drosophila gut induces immune responses to infectious bacteria and tolerance to microbiota. Cell Host Microbe 12 (2012), 153–165.
    • (2012) Cell Host Microbe , vol.12 , pp. 153-165
    • Bosco-Drayon, V.1    Poidevin, M.2    Boneca, I.G.3    Narbonne-Reveau, K.4    Royet, J.5    Charroux, B.6
  • 11
    • 84903939893 scopus 로고    scopus 로고
    • Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology
    • e01117–01114
    • Broderick, N.A., Buchon, N., Lemaitre, B., Microbiota-induced changes in drosophila melanogaster host gene expression and gut morphology. MBio, 5, 2014 e01117–01114.
    • (2014) MBio , vol.5
    • Broderick, N.A.1    Buchon, N.2    Lemaitre, B.3
  • 12
    • 84863870218 scopus 로고    scopus 로고
    • Gut-associated microbes of Drosophila melanogaster
    • Broderick, N.A., Lemaitre, B., Gut-associated microbes of Drosophila melanogaster. Gut Microbes 3 (2012), 307–321.
    • (2012) Gut Microbes , vol.3 , pp. 307-321
    • Broderick, N.A.1    Lemaitre, B.2
  • 13
    • 60649091298 scopus 로고    scopus 로고
    • Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation
    • Buchon, N., Broderick, N.A., Poidevin, M., Pradervand, S., Lemaitre, B., Drosophila intestinal response to bacterial infection: activation of host defense and stem cell proliferation. Cell Host Microbe 5 (2009), 200–211.
    • (2009) Cell Host Microbe , vol.5 , pp. 200-211
    • Buchon, N.1    Broderick, N.A.2    Poidevin, M.3    Pradervand, S.4    Lemaitre, B.5
  • 14
    • 84949626188 scopus 로고    scopus 로고
    • All for one and one for all: regionalization of the Drosophila intestine
    • Dec
    • Buchon, N., Osman, D., All for one and one for all: regionalization of the Drosophila intestine. Insect Biochem. Mol. Biol. 67 (2015 Dec), 2–8.
    • (2015) Insect Biochem. Mol. Biol. , vol.67 , pp. 2-8
    • Buchon, N.1    Osman, D.2
  • 15
    • 84878614163 scopus 로고    scopus 로고
    • Morphological and molecular characterization of adult midgut compartmentalization in Drosophila
    • Buchon, N., Osman, D., David, F.P., Fang, H.Y., Boquete, J.P., Deplancke, B., Lemaitre, B., Morphological and molecular characterization of adult midgut compartmentalization in Drosophila. Cell Rep. 3 (2013), 1725–1738.
    • (2013) Cell Rep. , vol.3 , pp. 1725-1738
    • Buchon, N.1    Osman, D.2    David, F.P.3    Fang, H.Y.4    Boquete, J.P.5    Deplancke, B.6    Lemaitre, B.7
  • 16
    • 84922481687 scopus 로고    scopus 로고
    • Immunity in Drosophila melanogaster–from microbial recognition to whole-organism physiology
    • Buchon, N., Silverman, N., Cherry, S., Immunity in Drosophila melanogaster–from microbial recognition to whole-organism physiology. Nat. Rev. Immunol. 14 (2014), 796–810.
    • (2014) Nat. Rev. Immunol. , vol.14 , pp. 796-810
    • Buchon, N.1    Silverman, N.2    Cherry, S.3
  • 17
    • 84905676671 scopus 로고    scopus 로고
    • The bacterial communities of Drosophila suzukii collected from undamaged cherries
    • Chandler, J.A., James, P.M., Jospin, G., Lang, J.M., The bacterial communities of Drosophila suzukii collected from undamaged cherries. PeerJ, 2, 2014, e474.
    • (2014) PeerJ , vol.2 , pp. e474
    • Chandler, J.A.1    James, P.M.2    Jospin, G.3    Lang, J.M.4
  • 18
    • 80053435147 scopus 로고    scopus 로고
    • Bacterial communities of diverse Drosophila species: ecological context of a host-microbe model system
    • Chandler, J.A., Lang, J.M., Bhatnagar, S., Eisen, J.A., Kopp, A., Bacterial communities of diverse Drosophila species: ecological context of a host-microbe model system. PLoS Genet., 7, 2011, e1002272.
    • (2011) PLoS Genet. , vol.7 , pp. e1002272
    • Chandler, J.A.1    Lang, J.M.2    Bhatnagar, S.3    Eisen, J.A.4    Kopp, A.5
  • 19
    • 33645236166 scopus 로고    scopus 로고
    • Structure of tracheal cytotoxin in complex with a heterodimeric pattern-recognition receptor
    • Chang, C.I., Chelliah, Y., Borek, D., Mengin-Lecreulx, D., Deisenhofer, J., Structure of tracheal cytotoxin in complex with a heterodimeric pattern-recognition receptor. Science 311 (2006), 1761–1764.
    • (2006) Science , vol.311 , pp. 1761-1764
    • Chang, C.I.1    Chelliah, Y.2    Borek, D.3    Mengin-Lecreulx, D.4    Deisenhofer, J.5
  • 20
    • 22544477068 scopus 로고    scopus 로고
    • Structure of the ectodomain of Drosophila peptidoglycan-recognition protein LCa suggests a molecular mechanism for pattern recognition
    • Chang, C.I., Ihara, K., Chelliah, Y., Mengin-Lecreulx, D., Wakatsuki, S., Deisenhofer, J., Structure of the ectodomain of Drosophila peptidoglycan-recognition protein LCa suggests a molecular mechanism for pattern recognition. Proc. Natl. Acad. Sci. U. S. A. 102 (2005), 10279–10284.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 10279-10284
    • Chang, C.I.1    Ihara, K.2    Chelliah, Y.3    Mengin-Lecreulx, D.4    Wakatsuki, S.5    Deisenhofer, J.6
  • 22
    • 84910052931 scopus 로고    scopus 로고
    • Age-associated loss of lamin-B leads to systemic inflammation and gut hyperplasia
    • Chen, H., Zheng, X., Zheng, Y., Age-associated loss of lamin-B leads to systemic inflammation and gut hyperplasia. Cell 159 (2014), 829–843.
    • (2014) Cell , vol.159 , pp. 829-843
    • Chen, H.1    Zheng, X.2    Zheng, Y.3
  • 23
    • 12844279852 scopus 로고    scopus 로고
    • Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor
    • Choe, K.M., Lee, H., Anderson, K.V., Drosophila peptidoglycan recognition protein LC (PGRP-LC) acts as a signal-transducing innate immune receptor. Proc. Natl. Acad. Sci. U. S. A. 102 (2005), 1122–1126.
    • (2005) Proc. Natl. Acad. Sci. U. S. A. , vol.102 , pp. 1122-1126
    • Choe, K.M.1    Lee, H.2    Anderson, K.V.3
  • 24
    • 0037066464 scopus 로고    scopus 로고
    • Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila
    • Choe, K.M., Werner, T., Stoven, S., Hultmark, D., Anderson, K.V., Requirement for a peptidoglycan recognition protein (PGRP) in Relish activation and antibacterial immune responses in Drosophila. Science 296 (2002), 359–362.
    • (2002) Science , vol.296 , pp. 359-362
    • Choe, K.M.1    Werner, T.2    Stoven, S.3    Hultmark, D.4    Anderson, K.V.5
  • 26
    • 78650866455 scopus 로고    scopus 로고
    • Enteric neurons and systemic signals couple nutritional and reproductive status with intestinal homeostasis
    • Cognigni, P., Bailey, A.P., Miguel-Aliaga, I., Enteric neurons and systemic signals couple nutritional and reproductive status with intestinal homeostasis. Cell Metab. 13 (2011), 92–104.
    • (2011) Cell Metab. , vol.13 , pp. 92-104
    • Cognigni, P.1    Bailey, A.P.2    Miguel-Aliaga, I.3
  • 28
    • 34147172817 scopus 로고    scopus 로고
    • Native microbial colonization of Drosophila melanogaster and its use as a model of Enterococcus faecalis pathogenesis
    • Cox, C.R., Gilmore, M.S., Native microbial colonization of Drosophila melanogaster and its use as a model of Enterococcus faecalis pathogenesis. Infect. Immun. 75 (2007), 1565–1576.
    • (2007) Infect. Immun. , vol.75 , pp. 1565-1576
    • Cox, C.R.1    Gilmore, M.S.2
  • 29
    • 0003314570 scopus 로고
    • Biology of drosophila
    • Demerec, M., Biology of drosophila. 1950.
    • (1950)
    • Demerec, M.1
  • 30
    • 84920862402 scopus 로고    scopus 로고
    • Multiorganismal insects: diversity and function of resident microorganisms
    • Douglas, A.E., Multiorganismal insects: diversity and function of resident microorganisms. Annu. Rev. Entomol. 60 (2015), 17–34.
    • (2015) Annu. Rev. Entomol. , vol.60 , pp. 17-34
    • Douglas, A.E.1
  • 31
    • 5144223809 scopus 로고    scopus 로고
    • Copper cells and stomach acid secretion in the Drosophila midgut
    • Dubreuil, R.R., Copper cells and stomach acid secretion in the Drosophila midgut. Int. J. Biochem. Cell Biol. 36 (2004), 745–752.
    • (2004) Int. J. Biochem. Cell Biol. , vol.36 , pp. 745-752
    • Dubreuil, R.R.1
  • 33
    • 84875239266 scopus 로고    scopus 로고
    • The complementary facets of epithelial host defenses in the genetic model organism Drosophila melanogaster: from resistance to resilience
    • Ferrandon, D., The complementary facets of epithelial host defenses in the genetic model organism Drosophila melanogaster: from resistance to resilience. Curr. Opin. Immunol. 25 (2013), 59–70.
    • (2013) Curr. Opin. Immunol. , vol.25 , pp. 59-70
    • Ferrandon, D.1
  • 34
    • 35549006674 scopus 로고    scopus 로고
    • The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections
    • Ferrandon, D., Imler, J.-L., Hetru, C., Hoffmann, J.A., The Drosophila systemic immune response: sensing and signalling during bacterial and fungal infections. Nat. Rev. Immunol. 7 (2007), 862–874.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 862-874
    • Ferrandon, D.1    Imler, J.-L.2    Hetru, C.3    Hoffmann, J.A.4
  • 35
    • 74549148895 scopus 로고    scopus 로고
    • Long-range activation of systemic immunity through peptidoglycan diffusion in Drosophila
    • Gendrin, M., Welchman, D.P., Poidevin, M., Herve, M., Lemaitre, B., Long-range activation of systemic immunity through peptidoglycan diffusion in Drosophila. PLoS Pathog., 5, 2009, e1000694.
    • (2009) PLoS Pathog. , vol.5 , pp. e1000694
    • Gendrin, M.1    Welchman, D.P.2    Poidevin, M.3    Herve, M.4    Lemaitre, B.5
  • 37
    • 0037061450 scopus 로고    scopus 로고
    • The Drosophila immune response against gram-negative bacteria is mediated by a peptidoglycan recognition protein
    • Gottar, M., Gobert, V., Michel, T., Belvin, M., Duyk, G., Hoffmann, J.A., Ferrandon, D., Royet, J., The Drosophila immune response against gram-negative bacteria is mediated by a peptidoglycan recognition protein. Nature 416 (2002), 640–644.
    • (2002) Nature , vol.416 , pp. 640-644
    • Gottar, M.1    Gobert, V.2    Michel, T.3    Belvin, M.4    Duyk, G.5    Hoffmann, J.A.6    Ferrandon, D.7    Royet, J.8
  • 38
    • 14844353929 scopus 로고    scopus 로고
    • Crystal structure of human peptidoglycan recognition protein S (PGRP-S) at 1.70 A resolution
    • Guan, R., Wang, Q., Sundberg, E.J., Mariuzza, R.A., Crystal structure of human peptidoglycan recognition protein S (PGRP-S) at 1.70 A resolution. J. Mol. Biol. 347 (2005), 683–691.
    • (2005) J. Mol. Biol. , vol.347 , pp. 683-691
    • Guan, R.1    Wang, Q.2    Sundberg, E.J.3    Mariuzza, R.A.4
  • 39
    • 84892714390 scopus 로고    scopus 로고
    • PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan
    • Guo, L., Karpac, J., Tran, S.L., Jasper, H., PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan. Cell 156 (2014), 109–122.
    • (2014) Cell , vol.156 , pp. 109-122
    • Guo, L.1    Karpac, J.2    Tran, S.L.3    Jasper, H.4
  • 40
    • 61749104447 scopus 로고    scopus 로고
    • Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity
    • Ha, E.M., Lee, K.A., Park, S.H., Kim, S.H., Nam, H.J., Lee, H.Y., Kang, D., Lee, W.J., Regulation of DUOX by the Galphaq-phospholipase Cbeta-Ca2+ pathway in Drosophila gut immunity. Dev. cell 16 (2009), 386–397.
    • (2009) Dev. cell , vol.16 , pp. 386-397
    • Ha, E.M.1    Lee, K.A.2    Park, S.H.3    Kim, S.H.4    Nam, H.J.5    Lee, H.Y.6    Kang, D.7    Lee, W.J.8
  • 41
    • 69049088645 scopus 로고    scopus 로고
    • Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut
    • Ha, E.M., Lee, K.A., Seo, Y.Y., Kim, S.H., Lim, J.H., Oh, B.H., Kim, J., Lee, W.J., Coordination of multiple dual oxidase-regulatory pathways in responses to commensal and infectious microbes in drosophila gut. Nat. Immunol. 10 (2009), 949–957.
    • (2009) Nat. Immunol. , vol.10 , pp. 949-957
    • Ha, E.M.1    Lee, K.A.2    Seo, Y.Y.3    Kim, S.H.4    Lim, J.H.5    Oh, B.H.6    Kim, J.7    Lee, W.J.8
  • 42
    • 27644498442 scopus 로고    scopus 로고
    • A direct role for dual oxidase in Drosophila gut immunity
    • Ha, E.M., Oh, C.T., Bae, Y.S., Lee, W.J., A direct role for dual oxidase in Drosophila gut immunity. Science 310 (2005), 847–850.
    • (2005) Science , vol.310 , pp. 847-850
    • Ha, E.M.1    Oh, C.T.2    Bae, Y.S.3    Lee, W.J.4
  • 43
    • 11244343895 scopus 로고    scopus 로고
    • An antioxidant system required for host protection against gut infection in Drosophila
    • Ha, E.M., Oh, C.T., Ryu, J.H., Bae, Y.S., Kang, S.W., Jang, I.H., Brey, P.T., Lee, W.J., An antioxidant system required for host protection against gut infection in Drosophila. Dev. Cell 8 (2005), 125–132.
    • (2005) Dev. Cell , vol.8 , pp. 125-132
    • Ha, E.M.1    Oh, C.T.2    Ryu, J.H.3    Bae, Y.S.4    Kang, S.W.5    Jang, I.H.6    Brey, P.T.7    Lee, W.J.8
  • 44
    • 70350737024 scopus 로고    scopus 로고
    • Regulation of midgut growth, development, and metamorphosis
    • Hakim, R.S., Baldwin, K., Smagghe, G., Regulation of midgut growth, development, and metamorphosis. Annu. Rev. Entomol. 55 (2010), 593–608.
    • (2010) Annu. Rev. Entomol. , vol.55 , pp. 593-608
    • Hakim, R.S.1    Baldwin, K.2    Smagghe, G.3
  • 45
    • 60549096559 scopus 로고    scopus 로고
    • New insights into peritrophic matrix synthesis, architecture, and function
    • Hegedus, D., Erlandson, M., Gillott, C., Toprak, U., New insights into peritrophic matrix synthesis, architecture, and function. Annu. Rev. Entomol. 54 (2009), 285–302.
    • (2009) Annu. Rev. Entomol. , vol.54 , pp. 285-302
    • Hegedus, D.1    Erlandson, M.2    Gillott, C.3    Toprak, U.4
  • 47
    • 84865386529 scopus 로고    scopus 로고
    • Immunity to the respiratory pathogen Bordetella pertussis
    • Higgs, R., Higgins, S.C., Ross, P.J., Mills, K.H., Immunity to the respiratory pathogen Bordetella pertussis. Mucosal Immunol. 5 (2012), 485–500.
    • (2012) Mucosal Immunol. , vol.5 , pp. 485-500
    • Higgs, R.1    Higgins, S.C.2    Ross, P.J.3    Mills, K.H.4
  • 48
    • 84940382448 scopus 로고    scopus 로고
    • Interactions between Drosophila and its natural yeast symbionts-Is Saccharomyces cerevisiae a good model for studying the fly-yeast relationship?
    • Hoang, D., Kopp, A., Chandler, J.A., Interactions between Drosophila and its natural yeast symbionts-Is Saccharomyces cerevisiae a good model for studying the fly-yeast relationship?. PeerJ, 3, 2015, e1116.
    • (2015) PeerJ , vol.3 , pp. e1116
    • Hoang, D.1    Kopp, A.2    Chandler, J.A.3
  • 49
    • 84901025110 scopus 로고    scopus 로고
    • The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling
    • Irving, A.T., Mimuro, H., Kufer, T.A., Lo, C., Wheeler, R., Turner, L.J., Thomas, B.J., Malosse, C., Gantier, M.P., Casillas, L.N., et al. The immune receptor NOD1 and kinase RIP2 interact with bacterial peptidoglycan on early endosomes to promote autophagy and inflammatory signaling. Cell Host Microbe 15 (2014), 623–635.
    • (2014) Cell Host Microbe , vol.15 , pp. 623-635
    • Irving, A.T.1    Mimuro, H.2    Kufer, T.A.3    Lo, C.4    Wheeler, R.5    Turner, L.J.6    Thomas, B.J.7    Malosse, C.8    Gantier, M.P.9    Casillas, L.N.10
  • 50
    • 80455173895 scopus 로고    scopus 로고
    • Intestinal stem cells in the adult Drosophila midgut
    • Jiang, H., Edgar, B.A., Intestinal stem cells in the adult Drosophila midgut. Exp. Cell Res. 317 (2011), 2780–2788.
    • (2011) Exp. Cell Res. , vol.317 , pp. 2780-2788
    • Jiang, H.1    Edgar, B.A.2
  • 51
    • 84865584204 scopus 로고    scopus 로고
    • Intestinal stem cell function in Drosophila and mice
    • Jiang, H., Edgar, B.A., Intestinal stem cell function in Drosophila and mice. Curr. Opin. Genet. Dev. 22 (2012), 354–360.
    • (2012) Curr. Opin. Genet. Dev. , vol.22 , pp. 354-360
    • Jiang, H.1    Edgar, B.A.2
  • 55
    • 15944420868 scopus 로고    scopus 로고
    • Bacterial recognition and signalling by the Drosophila IMD pathway
    • Kaneko, T., Silverman, N., Bacterial recognition and signalling by the Drosophila IMD pathway. Cell Microbiol. 7 (2005), 461–469.
    • (2005) Cell Microbiol. , vol.7 , pp. 461-469
    • Kaneko, T.1    Silverman, N.2
  • 56
  • 59
    • 0023896066 scopus 로고
    • Cellular organization and peritrophic membrane formation in the cardia (proventriculus) of Drosophila melanogaster
    • King, D.G., Cellular organization and peritrophic membrane formation in the cardia (proventriculus) of Drosophila melanogaster. J. Morphol. 196 (1988), 253–282.
    • (1988) J. Morphol. , vol.196 , pp. 253-282
    • King, D.G.1
  • 61
    • 84886091566 scopus 로고    scopus 로고
    • The Drosophila IMD pathway in the activation of the humoral immune response
    • Kleino, A., Silverman, N., The Drosophila IMD pathway in the activation of the humoral immune response. Dev. Comp. Immunol. 42 (2014), 25–35.
    • (2014) Dev. Comp. Immunol. , vol.42 , pp. 25-35
    • Kleino, A.1    Silverman, N.2
  • 62
    • 84864204550 scopus 로고    scopus 로고
    • Drosophila as a model system to unravel the layers of innate immunity to infection
    • Kounatidis, I., Ligoxygakis, P., Drosophila as a model system to unravel the layers of innate immunity to infection. Open Biol., 2, 2012, 120075.
    • (2012) Open Biol. , vol.2 , pp. 120075
    • Kounatidis, I.1    Ligoxygakis, P.2
  • 63
    • 80053166581 scopus 로고    scopus 로고
    • Genetic evidence for a protective role of the peritrophic matrix against intestinal bacterial infection in Drosophila melanogaster
    • Kuraishi, T., Binggeli, O., Opota, O., Buchon, N., Lemaitre, B., Genetic evidence for a protective role of the peritrophic matrix against intestinal bacterial infection in Drosophila melanogaster. Proc. Natl. Acad. Sci. U. S. A. 108 (2011), 15966–15971.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 15966-15971
    • Kuraishi, T.1    Binggeli, O.2    Opota, O.3    Buchon, N.4    Lemaitre, B.5
  • 64
    • 84922935450 scopus 로고    scopus 로고
    • Bacterial uracil modulates Drosophila DUOX-dependent gut immunity via Hedgehog-induced signaling endosomes
    • Lee, K.A., Kim, B., Bhin, J., Kim do, H., You, H., Kim, E.K., Kim, S.H., Ryu, J.H., Hwang, D., Lee, W.J., Bacterial uracil modulates Drosophila DUOX-dependent gut immunity via Hedgehog-induced signaling endosomes. Cell Host Microbe 17 (2015), 191–204.
    • (2015) Cell Host Microbe , vol.17 , pp. 191-204
    • Lee, K.A.1    Kim, B.2    Bhin, J.3    Kim do, H.4    You, H.5    Kim, E.K.6    Kim, S.H.7    Ryu, J.H.8    Hwang, D.9    Lee, W.J.10
  • 65
    • 84877723813 scopus 로고    scopus 로고
    • Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in Drosophila
    • Lee, K.A., Kim, S.H., Kim, E.K., Ha, E.M., You, H., Kim, B., Kim, M.J., Kwon, Y., Ryu, J.H., Lee, W.J., Bacterial-derived uracil as a modulator of mucosal immunity and gut-microbe homeostasis in Drosophila. Cell 153 (2013), 797–811.
    • (2013) Cell , vol.153 , pp. 797-811
    • Lee, K.A.1    Kim, S.H.2    Kim, E.K.3    Ha, E.M.4    You, H.5    Kim, B.6    Kim, M.J.7    Kwon, Y.8    Ryu, J.H.9    Lee, W.J.10
  • 66
    • 0030891189 scopus 로고    scopus 로고
    • Peritrophic matrix structure and function
    • Lehane, M.J., Peritrophic matrix structure and function. Annu. Rev. Entomol. 42 (1997), 525–550.
    • (1997) Annu. Rev. Entomol. , vol.42 , pp. 525-550
    • Lehane, M.J.1
  • 67
    • 84888602564 scopus 로고    scopus 로고
    • The digestive tract of Drosophila melanogaster
    • Lemaitre, B., Miguel-Aliaga, I., The digestive tract of Drosophila melanogaster. Annu. Rev. Genet. 47 (2013), 377–404.
    • (2013) Annu. Rev. Genet. , vol.47 , pp. 377-404
    • Lemaitre, B.1    Miguel-Aliaga, I.2
  • 68
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • Lemaitre, B., Nicolas, E., Michaut, L., Reichhart, J.M., Hoffmann, J.A., The dorsoventral regulatory gene cassette spatzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86 (1996), 973–983.
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 69
    • 40849111159 scopus 로고    scopus 로고
    • Crystal structure of Drosophila PGRP-SD suggests binding to DAP-type but not lysine-type peptidoglycan
    • Leone, P., Bischoff, V., Kellenberger, C., Hetru, C., Royet, J., Roussel, A., Crystal structure of Drosophila PGRP-SD suggests binding to DAP-type but not lysine-type peptidoglycan. Mol. Immunol. 45 (2008), 2521–2530.
    • (2008) Mol. Immunol. , vol.45 , pp. 2521-2530
    • Leone, P.1    Bischoff, V.2    Kellenberger, C.3    Hetru, C.4    Royet, J.5    Roussel, A.6
  • 70
    • 39449112512 scopus 로고    scopus 로고
    • Toll-like receptors–taking an evolutionary approach
    • Leulier, F., Lemaitre, B., Toll-like receptors–taking an evolutionary approach. Nat. Rev. Genet. 9 (2008), 165–178.
    • (2008) Nat. Rev. Genet. , vol.9 , pp. 165-178
    • Leulier, F.1    Lemaitre, B.2
  • 72
    • 0032496389 scopus 로고    scopus 로고
    • Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin
    • Levashina, E.A., Ohresser, S., Lemaitre, B., Imler, J.L., Two distinct pathways can control expression of the gene encoding the Drosophila antimicrobial peptide metchnikowin. J. Mol. Biol. 278 (1998), 515–527.
    • (1998) J. Mol. Biol. , vol.278 , pp. 515-527
    • Levashina, E.A.1    Ohresser, S.2    Lemaitre, B.3    Imler, J.L.4
  • 74
    • 84873838480 scopus 로고    scopus 로고
    • Trachea-derived dpp controls adult midgut homeostasis in Drosophila
    • Li, Z., Zhang, Y., Han, L., Shi, L., Lin, X., Trachea-derived dpp controls adult midgut homeostasis in Drosophila. Dev. cell 24 (2013), 133–143.
    • (2013) Dev. cell , vol.24 , pp. 133-143
    • Li, Z.1    Zhang, Y.2    Han, L.3    Shi, L.4    Lin, X.5
  • 75
    • 33745712561 scopus 로고    scopus 로고
    • Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model
    • Liehl, P., Blight, M., Vodovar, N., Boccard, F., Lemaitre, B., Prevalence of local immune response against oral infection in a Drosophila/Pseudomonas infection model. PLoS Pathog., 2, 2006, e56.
    • (2006) PLoS Pathog. , vol.2 , pp. e56
    • Liehl, P.1    Blight, M.2    Vodovar, N.3    Boccard, F.4    Lemaitre, B.5
  • 76
    • 33646378677 scopus 로고    scopus 로고
    • Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins
    • Lim, J.H., Kim, M.S., Kim, H.E., Yano, T., Oshima, Y., Aggarwal, K., Goldman, W.E., Silverman, N., Kurata, S., Oh, B.H., Structural basis for preferential recognition of diaminopimelic acid-type peptidoglycan by a subset of peptidoglycan recognition proteins. J. Biol. Chem. 281 (2006), 8286–8295.
    • (2006) J. Biol. Chem. , vol.281 , pp. 8286-8295
    • Lim, J.H.1    Kim, M.S.2    Kim, H.E.3    Yano, T.4    Oshima, Y.5    Aggarwal, K.6    Goldman, W.E.7    Silverman, N.8    Kurata, S.9    Oh, B.H.10
  • 77
    • 84886085385 scopus 로고    scopus 로고
    • Conventional and non-conventional Drosophila Toll signaling
    • Lindsay, S.A., Wasserman, S.A., Conventional and non-conventional Drosophila Toll signaling. Dev. Comp. Immunol. 42 (2014), 16–24.
    • (2014) Dev. Comp. Immunol. , vol.42 , pp. 16-24
    • Lindsay, S.A.1    Wasserman, S.A.2
  • 79
    • 43049157518 scopus 로고    scopus 로고
    • The Drosophila peptidoglycan recognition protein PGRP-LF blocks PGRP-LC and IMD/JNK pathway activation
    • Maillet, F., Bischoff, V., Vignal, C., Hoffmann, J., Royet, J., The Drosophila peptidoglycan recognition protein PGRP-LF blocks PGRP-LC and IMD/JNK pathway activation. Cell Host Microbe 3 (2008), 293–303.
    • (2008) Cell Host Microbe , vol.3 , pp. 293-303
    • Maillet, F.1    Bischoff, V.2    Vignal, C.3    Hoffmann, J.4    Royet, J.5
  • 81
    • 0037470091 scopus 로고    scopus 로고
    • A scavenger function for a Drosophila peptidoglycan recognition protein
    • Mellroth, P., Karlsson, J., Steiner, H., A scavenger function for a Drosophila peptidoglycan recognition protein. J. Biol. Chem. 278 (2003), 7059–7064.
    • (2003) J. Biol. Chem. , vol.278 , pp. 7059-7064
    • Mellroth, P.1    Karlsson, J.2    Steiner, H.3
  • 82
    • 33750091050 scopus 로고    scopus 로고
    • PGRP-SB1: an N-acetylmuramoyl L-alanine amidase with antibacterial activity
    • Mellroth, P., Steiner, H., PGRP-SB1: an N-acetylmuramoyl L-alanine amidase with antibacterial activity. Biochem. Biophys. Res. Commun. 350 (2006), 994–999.
    • (2006) Biochem. Biophys. Res. Commun. , vol.350 , pp. 994-999
    • Mellroth, P.1    Steiner, H.2
  • 83
    • 19044388766 scopus 로고    scopus 로고
    • Structure and metabolism of peptidoglycan and molecular requirements allowing its detection by the Drosophila innate immune system
    • Mengin-Lecreulx, D., Lemaitre, B., Structure and metabolism of peptidoglycan and molecular requirements allowing its detection by the Drosophila innate immune system. J. Endotoxin Res. 11 (2005), 105–111.
    • (2005) J. Endotoxin Res. , vol.11 , pp. 105-111
    • Mengin-Lecreulx, D.1    Lemaitre, B.2
  • 85
    • 31444452338 scopus 로고    scopus 로고
    • Evidence that stem cells reside in the adult Drosophila midgut epithelium
    • Micchelli, C.A., Perrimon, N., Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature 439 (2006), 475–479.
    • (2006) Nature , vol.439 , pp. 475-479
    • Micchelli, C.A.1    Perrimon, N.2
  • 86
    • 0035856990 scopus 로고    scopus 로고
    • Drosophila toll is activated by gram-positive bacteria through a circulating peptidoglycan recognition protein
    • Michel, T., Reichhart, J.M., Hoffmann, J.A., Royet, J., Drosophila toll is activated by gram-positive bacteria through a circulating peptidoglycan recognition protein. Nature 414 (2001), 756–759.
    • (2001) Nature , vol.414 , pp. 756-759
    • Michel, T.1    Reichhart, J.M.2    Hoffmann, J.A.3    Royet, J.4
  • 87
    • 84919818703 scopus 로고    scopus 로고
    • NOD-like receptors: versatile cytosolic sentinels
    • Motta, V., Soares, F., Sun, T., Philpott, D.J., NOD-like receptors: versatile cytosolic sentinels. Physiol. Rev. 95 (2015), 149–178.
    • (2015) Physiol. Rev. , vol.95 , pp. 149-178
    • Motta, V.1    Soares, F.2    Sun, T.3    Philpott, D.J.4
  • 90
    • 84864807751 scopus 로고    scopus 로고
    • Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE
    • Neyen, C., Poidevin, M., Roussel, A., Lemaitre, B., Tissue- and ligand-specific sensing of gram-negative infection in drosophila by PGRP-LC isoforms and PGRP-LE. J. Immunol. 189 (2012), 1886–1897.
    • (2012) J. Immunol. , vol.189 , pp. 1886-1897
    • Neyen, C.1    Poidevin, M.2    Roussel, A.3    Lemaitre, B.4
  • 91
    • 31444444485 scopus 로고    scopus 로고
    • The adult Drosophila posterior midgut is maintained by pluripotent stem cells
    • Ohlstein, B., Spradling, A., The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature 439 (2006), 470–474.
    • (2006) Nature , vol.439 , pp. 470-474
    • Ohlstein, B.1    Spradling, A.2
  • 93
    • 82055177179 scopus 로고    scopus 로고
    • Negative regulation by amidase PGRPs shapes the Drosophila antibacterial response and protects the fly from innocuous infection
    • Paredes, J.C., Welchman, D.P., Poidevin, M., Lemaitre, B., Negative regulation by amidase PGRPs shapes the Drosophila antibacterial response and protects the fly from innocuous infection. Immunity 35 (2011), 770–779.
    • (2011) Immunity , vol.35 , pp. 770-779
    • Paredes, J.C.1    Welchman, D.P.2    Poidevin, M.3    Lemaitre, B.4
  • 94
    • 84918781486 scopus 로고    scopus 로고
    • The nonaspanins TM9SF2 and TM9SF4 regulate the plasma membrane localization and signalling activity of the peptidoglycan recognition protein PGRP-LC in Drosophila
    • Perrin, J., Mortier, M., Jacomin, A.C., Viargues, P., Thevenon, D., Fauvarque, M.O., The nonaspanins TM9SF2 and TM9SF4 regulate the plasma membrane localization and signalling activity of the peptidoglycan recognition protein PGRP-LC in Drosophila. J. Innate Immun. 7 (2015), 37–46.
    • (2015) J. Innate Immun. , vol.7 , pp. 37-46
    • Perrin, J.1    Mortier, M.2    Jacomin, A.C.3    Viargues, P.4    Thevenon, D.5    Fauvarque, M.O.6
  • 95
    • 35449002517 scopus 로고    scopus 로고
    • Peptidoglycan recognition protein LF: a negative regulator of Drosophila immunity
    • Persson, C., Oldenvi, S., Steiner, H., Peptidoglycan recognition protein LF: a negative regulator of Drosophila immunity. Insect Biochem. Mol. Biol. 37 (2007), 1309–1316.
    • (2007) Insect Biochem. Mol. Biol. , vol.37 , pp. 1309-1316
    • Persson, C.1    Oldenvi, S.2    Steiner, H.3
  • 97
    • 0037061482 scopus 로고    scopus 로고
    • Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli
    • Ramet, M., Manfruelli, P., Pearson, A., Mathey-Prevot, B., Ezekowitz, R.A., Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli. Nature 416 (2002), 644–648.
    • (2002) Nature , vol.416 , pp. 644-648
    • Ramet, M.1    Manfruelli, P.2    Pearson, A.3    Mathey-Prevot, B.4    Ezekowitz, R.A.5
  • 98
    • 84936996066 scopus 로고    scopus 로고
    • Molecular mechanisms for the evolution of bacterial morphologies and growth modes
    • Randich, A.M., Brun, Y.V., Molecular mechanisms for the evolution of bacterial morphologies and growth modes. Front. Microbiol., 6, 2015, 580.
    • (2015) Front. Microbiol. , vol.6 , pp. 580
    • Randich, A.M.1    Brun, Y.V.2
  • 99
    • 0032078495 scopus 로고    scopus 로고
    • Molecular adaptation of Drosophila melanogaster lysozymes to a digestive function
    • Regel, R., Matioli, S.R., Terra, W.R., Molecular adaptation of Drosophila melanogaster lysozymes to a digestive function. Insect Biochem. Mol. Biol. 28 (1998), 309–319.
    • (1998) Insect Biochem. Mol. Biol. , vol.28 , pp. 309-319
    • Regel, R.1    Matioli, S.R.2    Terra, W.R.3
  • 100
    • 34547440528 scopus 로고    scopus 로고
    • Increased internal and external bacterial load during Drosophila aging without life-span trade-off
    • Ren, C., Webster, P., Finkel, S.E., Tower, J., Increased internal and external bacterial load during Drosophila aging without life-span trade-off. Cell Metab. 6 (2007), 144–152.
    • (2007) Cell Metab. , vol.6 , pp. 144-152
    • Ren, C.1    Webster, P.2    Finkel, S.E.3    Tower, J.4
  • 101
    • 84877285395 scopus 로고    scopus 로고
    • Mechanisms and consequence of bacteria detection by the Drosophila gut epithelium
    • Royet, J., Charroux, B., Mechanisms and consequence of bacteria detection by the Drosophila gut epithelium. Gut Microbes 4 (2013), 259–263.
    • (2013) Gut Microbes , vol.4 , pp. 259-263
    • Royet, J.1    Charroux, B.2
  • 102
    • 85027958029 scopus 로고    scopus 로고
    • Peptidoglycan recognition proteins: modulators of the microbiome and inflammation
    • Royet, J., Gupta, D., Dziarski, R., Peptidoglycan recognition proteins: modulators of the microbiome and inflammation. Nat. Rev. Immunol. 11 (2011), 837–851.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 837-851
    • Royet, J.1    Gupta, D.2    Dziarski, R.3
  • 103
    • 85027958029 scopus 로고    scopus 로고
    • Peptidoglycan recognition proteins: modulators of the microbiome and inflammation
    • Royet, J., Gupta, D., Dziarski, R., Peptidoglycan recognition proteins: modulators of the microbiome and inflammation. Nat. Rev. Immunol. 11 (2011), 837–851.
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 837-851
    • Royet, J.1    Gupta, D.2    Dziarski, R.3
  • 106
    • 77956306627 scopus 로고    scopus 로고
    • Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-gamma
    • Saha, S., Jing, X., Park, S.Y., Wang, S., Li, X., Gupta, D., Dziarski, R., Peptidoglycan recognition proteins protect mice from experimental colitis by promoting normal gut flora and preventing induction of interferon-gamma. Cell Host Microbe 8 (2010), 147–162.
    • (2010) Cell Host Microbe , vol.8 , pp. 147-162
    • Saha, S.1    Jing, X.2    Park, S.Y.3    Wang, S.4    Li, X.5    Gupta, D.6    Dziarski, R.7
  • 107
    • 31544441655 scopus 로고    scopus 로고
    • Electrogenic H+ transport and pH gradients generated by a V-H+ -ATPase in the isolated perfused larval Drosophila midgut
    • Shanbhag, S., Tripathi, S., Electrogenic H+ transport and pH gradients generated by a V-H+ -ATPase in the isolated perfused larval Drosophila midgut. J. Membr. Biol. 206 (2005), 61–72.
    • (2005) J. Membr. Biol. , vol.206 , pp. 61-72
    • Shanbhag, S.1    Tripathi, S.2
  • 109
    • 84946093769 scopus 로고    scopus 로고
    • Crosslinking of a peritrophic matrix protein protects gut epithelia from bacterial exotoxins
    • Shibata, T., Maki, K., Hadano, J., Fujikawa, T., Kitazaki, K., Koshiba, T., Kawabata, S., Crosslinking of a peritrophic matrix protein protects gut epithelia from bacterial exotoxins. PLoS Pathog., 11, 2015, e1005244.
    • (2015) PLoS Pathog. , vol.11 , pp. e1005244
    • Shibata, T.1    Maki, K.2    Hadano, J.3    Fujikawa, T.4    Kitazaki, K.5    Koshiba, T.6    Kawabata, S.7
  • 110
    • 84880894883 scopus 로고    scopus 로고
    • Transglutaminase-catalyzed protein-protein cross-linking suppresses the activity of the NF-kappaB-like transcription factor relish
    • Shibata, T., Sekihara, S., Fujikawa, T., Miyaji, R., Maki, K., Ishihara, T., Koshiba, T., Kawabata, S., Transglutaminase-catalyzed protein-protein cross-linking suppresses the activity of the NF-kappaB-like transcription factor relish. Sci. Signal, 6, 2013, ra61.
    • (2013) Sci. Signal , vol.6 , pp. ra61
    • Shibata, T.1    Sekihara, S.2    Fujikawa, T.3    Miyaji, R.4    Maki, K.5    Ishihara, T.6    Koshiba, T.7    Kawabata, S.8
  • 111
    • 80555143077 scopus 로고    scopus 로고
    • Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling
    • Shin, S.C., Kim, S.H., You, H., Kim, B., Kim, A.C., Lee, K.A., Yoon, J.H., Ryu, J.H., Lee, W.J., Drosophila microbiome modulates host developmental and metabolic homeostasis via insulin signaling. Science 334 (2011), 670–674.
    • (2011) Science , vol.334 , pp. 670-674
    • Shin, S.C.1    Kim, S.H.2    You, H.3    Kim, B.4    Kim, A.C.5    Lee, K.A.6    Yoon, J.H.7    Ryu, J.H.8    Lee, W.J.9
  • 112
    • 84876414806 scopus 로고    scopus 로고
    • The gut microbiota–masters of host development and physiology
    • Sommer, F., Backhed, F., The gut microbiota–masters of host development and physiology. Nat. Rev. Microbiol. 11 (2013), 227–238.
    • (2013) Nat. Rev. Microbiol. , vol.11 , pp. 227-238
    • Sommer, F.1    Backhed, F.2
  • 113
    • 84881539010 scopus 로고    scopus 로고
    • Host species and environmental effects on bacterial communities associated with Drosophila in the laboratory and in the natural environment
    • Staubach, F., Baines, J.F., Kunzel, S., Bik, E.M., Petrov, D.A., Host species and environmental effects on bacterial communities associated with Drosophila in the laboratory and in the natural environment. PLoS One, 8, 2013, e70749.
    • (2013) PLoS One , vol.8 , pp. e70749
    • Staubach, F.1    Baines, J.F.2    Kunzel, S.3    Bik, E.M.4    Petrov, D.A.5
  • 116
    • 80052774197 scopus 로고    scopus 로고
    • Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing
    • Storelli, G., Defaye, A., Erkosar, B., Hols, P., Royet, J., Leulier, F., Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing. Cell Metab. 14 (2011), 403–414.
    • (2011) Cell Metab. , vol.14 , pp. 403-414
    • Storelli, G.1    Defaye, A.2    Erkosar, B.3    Hols, P.4    Royet, J.5    Leulier, F.6
  • 118
    • 0037108754 scopus 로고    scopus 로고
    • Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae
    • Takehana, A., Katsuyama, T., Yano, T., Oshima, Y., Takada, H., Aigaki, T., Kurata, S., Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae. Proc. Natl. Acad. Sci. U. S. A. 99 (2002), 13705–13710.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 13705-13710
    • Takehana, A.1    Katsuyama, T.2    Yano, T.3    Oshima, Y.4    Takada, H.5    Aigaki, T.6    Kurata, S.7
  • 119
    • 10644267665 scopus 로고    scopus 로고
    • Peptidoglycan recognition protein (PGRP)-LE and PGRP-LC act synergistically in Drosophila immunity
    • Takehana, A., Yano, T., Mita, S., Kotani, A., Oshima, Y., Kurata, S., Peptidoglycan recognition protein (PGRP)-LE and PGRP-LC act synergistically in Drosophila immunity. EMBO J. 23 (2004), 4690–4700.
    • (2004) EMBO J. , vol.23 , pp. 4690-4700
    • Takehana, A.1    Yano, T.2    Mita, S.3    Kotani, A.4    Oshima, Y.5    Kurata, S.6
  • 120
    • 84875808743 scopus 로고    scopus 로고
    • Homeostatic epithelial renewal in the gut is required for dampening a fatal systemic wound response in Drosophila
    • Takeishi, A., Kuranaga, E., Tonoki, A., Misaki, K., Yonemura, S., Kanuka, H., Miura, M., Homeostatic epithelial renewal in the gut is required for dampening a fatal systemic wound response in Drosophila. Cell Rep. 3 (2013), 919–930.
    • (2013) Cell Rep. , vol.3 , pp. 919-930
    • Takeishi, A.1    Kuranaga, E.2    Tonoki, A.3    Misaki, K.4    Yonemura, S.5    Kanuka, H.6    Miura, M.7
  • 121
    • 0024199846 scopus 로고
    • Physiology and biochemistry of insect digestion: an evolutionary perspective
    • Terra, W.R., Physiology and biochemistry of insect digestion: an evolutionary perspective. Braz J. Med. Biol. Res. 21 (1988), 675–734.
    • (1988) Braz J. Med. Biol. Res. , vol.21 , pp. 675-734
    • Terra, W.R.1
  • 124
    • 67749098054 scopus 로고    scopus 로고
    • Interactions between mutualist Wigglesworthia and tsetse peptidoglycan recognition protein (PGRP-LB) influence trypanosome transmission
    • Wang, J., Wu, Y., Yang, G., Aksoy, S., Interactions between mutualist Wigglesworthia and tsetse peptidoglycan recognition protein (PGRP-LB) influence trypanosome transmission. Proc. Natl. Acad. Sci. U. S. A. 106 (2009), 12133–12138.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 12133-12138
    • Wang, J.1    Wu, Y.2    Yang, G.3    Aksoy, S.4
  • 125
    • 33750218690 scopus 로고    scopus 로고
    • Sensing of gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA
    • Wang, L., Weber, A.N., Atilano, M.L., Filipe, S.R., Gay, N.J., Ligoxygakis, P., Sensing of gram-positive bacteria in Drosophila: GNBP1 is needed to process and present peptidoglycan to PGRP-SA. EMBO J. 25 (2006), 5005–5014.
    • (2006) EMBO J. , vol.25 , pp. 5005-5014
    • Wang, L.1    Weber, A.N.2    Atilano, M.L.3    Filipe, S.R.4    Gay, N.J.5    Ligoxygakis, P.6
  • 126
    • 0038036294 scopus 로고    scopus 로고
    • Functional diversity of the Drosophila PGRP-LC gene cluster in the response to lipopolysaccharide and peptidoglycan
    • Werner, T., Borge-Renberg, K., Mellroth, P., Steiner, H., Hultmark, D., Functional diversity of the Drosophila PGRP-LC gene cluster in the response to lipopolysaccharide and peptidoglycan. J. Biol. Chem. 278 (2003), 26319–26322.
    • (2003) J. Biol. Chem. , vol.278 , pp. 26319-26322
    • Werner, T.1    Borge-Renberg, K.2    Mellroth, P.3    Steiner, H.4    Hultmark, D.5
  • 127
    • 84902652818 scopus 로고    scopus 로고
    • The biology of bacterial peptidoglycans and their impact on host immunity and physiology
    • Wheeler, R., Chevalier, G., Eberl, G., Gomperts Boneca, I., The biology of bacterial peptidoglycans and their impact on host immunity and physiology. Cell Microbiol. 16 (2014), 1014–1023.
    • (2014) Cell Microbiol. , vol.16 , pp. 1014-1023
    • Wheeler, R.1    Chevalier, G.2    Eberl, G.3    Gomperts Boneca, I.4
  • 128
    • 84884675234 scopus 로고    scopus 로고
    • The inconstant gut microbiota of Drosophila species revealed by 16S rRNA gene analysis
    • Wong, A.C., Chaston, J.M., Douglas, A.E., The inconstant gut microbiota of Drosophila species revealed by 16S rRNA gene analysis. ISME J. 7 (2013), 1922–1932.
    • (2013) ISME J. , vol.7 , pp. 1922-1932
    • Wong, A.C.1    Chaston, J.M.2    Douglas, A.E.3
  • 129
    • 84945290769 scopus 로고    scopus 로고
    • The host as the driver of the microbiota in the gut and external environment of Drosophila melanogaster
    • Wong, A.C., Luo, Y., Jing, X., Franzenburg, S., Bost, A., Douglas, A.E., The host as the driver of the microbiota in the gut and external environment of Drosophila melanogaster. Appl. Environ. Microbiol. 81 (2015), 6232–6240.
    • (2015) Appl. Environ. Microbiol. , vol.81 , pp. 6232-6240
    • Wong, A.C.1    Luo, Y.2    Jing, X.3    Franzenburg, S.4    Bost, A.5    Douglas, A.E.6
  • 130
    • 79959841282 scopus 로고    scopus 로고
    • Low-diversity bacterial community in the gut of the fruitfly Drosophila melanogaster
    • Wong, C.N., Ng, P., Douglas, A.E., Low-diversity bacterial community in the gut of the fruitfly Drosophila melanogaster. Environ. Microbiol. 13 (2011), 1889–1900.
    • (2011) Environ. Microbiol. , vol.13 , pp. 1889-1900
    • Wong, C.N.1    Ng, P.2    Douglas, A.E.3
  • 132
    • 84903590359 scopus 로고    scopus 로고
    • Homeostasis between gut-associated microorganisms and the immune system in Drosophila
    • You, H., Lee, W.J., Lee, W.J., Homeostasis between gut-associated microorganisms and the immune system in Drosophila. Curr. Opin. Immunol. 30 (2014), 48–53.
    • (2014) Curr. Opin. Immunol. , vol.30 , pp. 48-53
    • You, H.1    Lee, W.J.2    Lee, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.