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Volumn 16, Issue 1, 2015, Pages

Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ANEUPLOIDY; ANIMAL; BRAIN; CHROMOSOME 21; CPG ISLAND; DISEASE MODEL; DNA METHYLATION; DOWN SYNDROME; FETUS; GENETIC EPIGENESIS; GENETICS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MOUSE; PATHOLOGY; T LYMPHOCYTE;

EID: 84955683597     PISSN: 14747596     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-015-0827-6     Document Type: Article
Times cited : (66)

References (106)
  • 4
    • 84864992390 scopus 로고    scopus 로고
    • Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells
    • Katsushima K, Shinjo K, Natsume A, Ohka F, Fujii M, Osada H, et al. Contribution of microRNA-1275 to Claudin11 protein suppression via a polycomb-mediated silencing mechanism in human glioma stem-like cells. J Biol Chem. 2012;287:27396-406.
    • (2012) J Biol Chem. , vol.287 , pp. 27396-27406
    • Katsushima, K.1    Shinjo, K.2    Natsume, A.3    Ohka, F.4    Fujii, M.5    Osada, H.6
  • 6
    • 84859412462 scopus 로고    scopus 로고
    • Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex
    • Bakulski KM, Dolinoy DC, Sartor MA, Paulson HL, Konen JR, Lieberman AP, et al. Genome-wide DNA methylation differences between late-onset Alzheimer's disease and cognitively normal controls in human frontal cortex. J Alzheimers Dis. 2012;29:571-88.
    • (2012) J Alzheimers Dis. , vol.29 , pp. 571-588
    • Bakulski, K.M.1    Dolinoy, D.C.2    Sartor, M.A.3    Paulson, H.L.4    Konen, J.R.5    Lieberman, A.P.6
  • 7
    • 84929296885 scopus 로고    scopus 로고
    • Alterations in global DNA methylation and hydroxymethylation are not detected in Alzheimer's disease
    • Lashley T, Gami P, Valizadeh N, Li A, Revesz T, Balazs R. Alterations in global DNA methylation and hydroxymethylation are not detected in Alzheimer's disease. Neuropathol Appl Neurobiol. 2015; 41:497-506.
    • (2015) Neuropathol Appl Neurobiol. , vol.41 , pp. 497-506
    • Lashley, T.1    Gami, P.2    Valizadeh, N.3    Li, A.4    Revesz, T.5    Balazs, R.6
  • 8
    • 0031573959 scopus 로고    scopus 로고
    • Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures
    • Manley NR, Capecchi MR. Hox group 3 paralogous genes act synergistically in the formation of somitic and neural crest-derived structures. Dev Biol. 1997;192:274-88.
    • (1997) Dev Biol. , vol.192 , pp. 274-288
    • Manley, N.R.1    Capecchi, M.R.2
  • 9
    • 0038105343 scopus 로고    scopus 로고
    • Somatic motoneurone specification in the hindbrain: the influence of somite-derived signals, retinoic acid and Hoxa3
    • Guidato S, Prin F, Guthrie S. Somatic motoneurone specification in the hindbrain: the influence of somite-derived signals, retinoic acid and Hoxa3. Development. 2003;130:2981-96.
    • (2003) Development. , vol.130 , pp. 2981-2996
    • Guidato, S.1    Prin, F.2    Guthrie, S.3
  • 10
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adult microglia derive from primitive macrophages
    • Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science. 2010;330:841-5.
    • (2010) Science. , vol.330 , pp. 841-845
    • Ginhoux, F.1    Greter, M.2    Leboeuf, M.3    Nandi, S.4    See, P.5    Gokhan, S.6
  • 11
    • 67649344477 scopus 로고    scopus 로고
    • Methylation-sensitive regulation of TMS1/ASC by the Ets factor, GA-binding protein-alpha
    • Lucas ME, Crider KS, Powell DR, Kapoor-Vazirani P, Vertino PM. Methylation-sensitive regulation of TMS1/ASC by the Ets factor, GA-binding protein-alpha. J Biol Chem. 2009;284:14698-709.
    • (2009) J Biol Chem. , vol.284 , pp. 14698-14709
    • Lucas, M.E.1    Crider, K.S.2    Powell, D.R.3    Kapoor-Vazirani, P.4    Vertino, P.M.5
  • 12
    • 73349130011 scopus 로고    scopus 로고
    • The role of Runx1/AML1 and Evi-1 in the regulation of hematopoietic stem cells
    • Kumano K, Kurokawa M. The role of Runx1/AML1 and Evi-1 in the regulation of hematopoietic stem cells. J Cell Physiol. 2010;222:282-5.
    • (2010) J Cell Physiol. , vol.222 , pp. 282-285
    • Kumano, K.1    Kurokawa, M.2
  • 13
    • 25844493155 scopus 로고    scopus 로고
    • Hematopoietic stem cell fate is established by the Notch-Runx pathway
    • Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 2005;19:2331-42.
    • (2005) Genes Dev. , vol.19 , pp. 2331-2342
    • Burns, C.E.1    Traver, D.2    Mayhall, E.3    Shepard, J.L.4    Zon, L.I.5
  • 14
    • 79751532529 scopus 로고    scopus 로고
    • Activation of a novel palmitoyltransferase ZDHHC14 in acute biphenotypic leukemia and subsets of acute myeloid leukemia
    • Yu L, Reader JC, Chen C, Zhao XF, Ha JS, Lee C, et al. Activation of a novel palmitoyltransferase ZDHHC14 in acute biphenotypic leukemia and subsets of acute myeloid leukemia. Leukemia. 2011;25:367-71.
    • (2011) Leukemia. , vol.25 , pp. 367-371
    • Yu, L.1    Reader, J.C.2    Chen, C.3    Zhao, X.F.4    Ha, J.S.5    Lee, C.6
  • 15
    • 84878085003 scopus 로고    scopus 로고
    • Accelerated aging in HIV/AIDS: novel biomarkers of senescent human CD8+ T cells
    • Chou JP, Ramirez CM, Wu JE, Effros RB. Accelerated aging in HIV/AIDS: novel biomarkers of senescent human CD8+ T cells. PLoS One. 2013;8, e64702.
    • (2013) PLoS One. , vol.8
    • Chou, J.P.1    Ramirez, C.M.2    Wu, J.E.3    Effros, R.B.4
  • 16
    • 66149123748 scopus 로고    scopus 로고
    • The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain
    • Kriaucionis S, Heintz N. The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain. Science. 2009;324:929-30.
    • (2009) Science. , vol.324 , pp. 929-930
    • Kriaucionis, S.1    Heintz, N.2
  • 18
    • 84874252793 scopus 로고    scopus 로고
    • Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis
    • Hahn MA, Qiu R, Wu X, Li AX, Zhang H, Wang J, et al. Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis. Cell Rep. 2013;3:291-300.
    • (2013) Cell Rep. , vol.3 , pp. 291-300
    • Hahn, M.A.1    Qiu, R.2    Wu, X.3    Li, A.X.4    Zhang, H.5    Wang, J.6
  • 19
    • 0037451123 scopus 로고    scopus 로고
    • AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats
    • Kuja-Panula J, Kiiltomaki M, Yamashiro T, Rouhiainen A, Rauvala H. AMIGO, a transmembrane protein implicated in axon tract development, defines a novel protein family with leucine-rich repeats. J Cell Biol. 2003;160:963-73.
    • (2003) J Cell Biol. , vol.160 , pp. 963-973
    • Kuja-Panula, J.1    Kiiltomaki, M.2    Yamashiro, T.3    Rouhiainen, A.4    Rauvala, H.5
  • 20
    • 44249105664 scopus 로고    scopus 로고
    • Early forebrain wiring: genetic dissection using conditional Celsr3 mutant mice
    • Zhou L, Bar I, Achouri Y, Campbell K, De Backer O, Hebert JM, et al. Early forebrain wiring: genetic dissection using conditional Celsr3 mutant mice. Science. 2008;320:946-9.
    • (2008) Science. , vol.320 , pp. 946-949
    • Zhou, L.1    Bar, I.2    Achouri, Y.3    Campbell, K.4    Backer, O.5    Hebert, J.M.6
  • 23
    • 84908043518 scopus 로고    scopus 로고
    • Protocadherins in neurological diseases
    • Hirabayashi T, Yagi T. Protocadherins in neurological diseases. Adv Neurobiol. 2014;8:293-314.
    • (2014) Adv Neurobiol. , vol.8 , pp. 293-314
    • Hirabayashi, T.1    Yagi, T.2
  • 25
    • 76249090489 scopus 로고    scopus 로고
    • BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources
    • Wu C, Orozco C, Boyer J, Leglise M, Goodale J, Batalov S, et al. BioGPS: an extensible and customizable portal for querying and organizing gene annotation resources. Genome Biol. 2009;10:R130.
    • (2009) Genome Biol. , vol.10 , pp. R130
    • Wu, C.1    Orozco, C.2    Boyer, J.3    Leglise, M.4    Goodale, J.5    Batalov, S.6
  • 27
    • 84877725488 scopus 로고    scopus 로고
    • (Poly)combing the pediatric cancer genome for answers
    • Morgan MA, Shilatifard A. (Poly)combing the pediatric cancer genome for answers. Science. 2013;340:823-4.
    • (2013) Science , vol.340 , pp. 823-824
    • Morgan, M.A.1    Shilatifard, A.2
  • 28
    • 84884908275 scopus 로고    scopus 로고
    • Promoter-like sequences regulating transcriptional activity in neurexin and neuroligin genes
    • Runkel F, Rohlmann A, Reissner C, Brand SM, Missler M. Promoter-like sequences regulating transcriptional activity in neurexin and neuroligin genes. J Neurochem. 2013;127:36-47.
    • (2013) J Neurochem. , vol.127 , pp. 36-47
    • Runkel, F.1    Rohlmann, A.2    Reissner, C.3    Brand, S.M.4    Missler, M.5
  • 29
    • 84877956152 scopus 로고    scopus 로고
    • Unliganded progesterone receptor-mediated targeting of an RNA-containing repressive complex silences a subset of hormone-inducible genes
    • Vicent GP, Nacht AS, Zaurin R, Font-Mateu J, Soronellas D, Le Dily F, et al. Unliganded progesterone receptor-mediated targeting of an RNA-containing repressive complex silences a subset of hormone-inducible genes. Genes Dev. 2013;27:1179-97.
    • (2013) Genes Dev. , vol.27 , pp. 1179-1197
    • Vicent, G.P.1    Nacht, A.S.2    Zaurin, R.3    Font-Mateu, J.4    Soronellas, D.5    Dily, F.6
  • 31
    • 77954572735 scopus 로고    scopus 로고
    • Long noncoding RNA as modular scaffold of histone modification complexes
    • Tsai MC, Manor O, Wan Y, Mosammaparast N, Wang JK, Lan F, et al. Long noncoding RNA as modular scaffold of histone modification complexes. Science. 2010;329:689-93.
    • (2010) Science. , vol.329 , pp. 689-693
    • Tsai, M.C.1    Manor, O.2    Wan, Y.3    Mosammaparast, N.4    Wang, J.K.5    Lan, F.6
  • 32
    • 84863012512 scopus 로고    scopus 로고
    • Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors
    • Yu M, Mazor T, Huang H, Huang HT, Kathrein KL, Woo AJ, et al. Direct recruitment of polycomb repressive complex 1 to chromatin by core binding transcription factors. Mol Cell. 2012;45:330-43.
    • (2012) Mol Cell. , vol.45 , pp. 330-343
    • Yu, M.1    Mazor, T.2    Huang, H.3    Huang, H.T.4    Kathrein, K.L.5    Woo, A.J.6
  • 33
    • 33750950626 scopus 로고    scopus 로고
    • Concomitant aberrant overexpression of RUNX1 and NCAM in regenerating bone marrow of myeloid leukemia of Down's syndrome
    • Langebrake C, Klusmann JH, Wortmann K, Kolar M, Puhlmann U, Reinhardt D. Concomitant aberrant overexpression of RUNX1 and NCAM in regenerating bone marrow of myeloid leukemia of Down's syndrome. Haematologica. 2006;91:1473-80.
    • (2006) Haematologica. , vol.91 , pp. 1473-1480
    • Langebrake, C.1    Klusmann, J.H.2    Wortmann, K.3    Kolar, M.4    Puhlmann, U.5    Reinhardt, D.6
  • 34
    • 84892690160 scopus 로고    scopus 로고
    • Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions
    • Feldmann A, Ivanek R, Murr R, Gaidatzis D, Burger L, Schubeler D. Transcription factor occupancy can mediate active turnover of DNA methylation at regulatory regions. PLoS Genet. 2013;9, e1003994.
    • (2013) PLoS Genet. , vol.9
    • Feldmann, A.1    Ivanek, R.2    Murr, R.3    Gaidatzis, D.4    Burger, L.5    Schubeler, D.6
  • 35
    • 84865836579 scopus 로고    scopus 로고
    • Widespread plasticity in CTCF occupancy linked to DNA methylation
    • Wang H, Maurano MT, Qu H, Varley KE, Gertz J, Pauli F, et al. Widespread plasticity in CTCF occupancy linked to DNA methylation. Genome Res. 2012;22:1680-8.
    • (2012) Genome Res. , vol.22 , pp. 1680-1688
    • Wang, H.1    Maurano, M.T.2    Qu, H.3    Varley, K.E.4    Gertz, J.5    Pauli, F.6
  • 37
    • 84872706701 scopus 로고    scopus 로고
    • IL-2 expression in activated human memory FOXP3(+) cells critically depends on the cellular levels of FOXP3 as well as of four transcription factors of T cell activation
    • Bendfeldt H, Benary M, Scheel T, Steinbrink K, Radbruch A, Herzel H, et al. IL-2 expression in activated human memory FOXP3(+) cells critically depends on the cellular levels of FOXP3 as well as of four transcription factors of T cell activation. Front Immunol. 2012;3:264.
    • (2012) Front Immunol. , vol.3 , pp. 264
    • Bendfeldt, H.1    Benary, M.2    Scheel, T.3    Steinbrink, K.4    Radbruch, A.5    Herzel, H.6
  • 38
    • 84898965274 scopus 로고    scopus 로고
    • c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs
    • Gustems M, Woellmer A, Rothbauer U, Eck SH, Wieland T, Lutter D, et al. c-Jun/c-Fos heterodimers regulate cellular genes via a newly identified class of methylated DNA sequence motifs. Nucleic Acids Res. 2014;42:3059-72.
    • (2014) Nucleic Acids Res , vol.42 , pp. 3059-3072
    • Gustems, M.1    Woellmer, A.2    Rothbauer, U.3    Eck, S.H.4    Wieland, T.5    Lutter, D.6
  • 40
    • 84878489387 scopus 로고    scopus 로고
    • HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages
    • Barneda-Zahonero B, Roman-Gonzalez L, Collazo O, Rafati H, Islam AB, Bussmann LH, et al. HDAC7 is a repressor of myeloid genes whose downregulation is required for transdifferentiation of pre-B cells into macrophages. PLoS Genet. 2013;9, e1003503.
    • (2013) PLoS Genet. , vol.9
    • Barneda-Zahonero, B.1    Roman-Gonzalez, L.2    Collazo, O.3    Rafati, H.4    Islam, A.B.5    Bussmann, L.H.6
  • 41
    • 84870283741 scopus 로고    scopus 로고
    • B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1
    • Karnowski A, Chevrier S, Belz GT, Mount A, Emslie D, D'Costa K, et al. B and T cells collaborate in antiviral responses via IL-6, IL-21, and transcriptional activator and coactivator, Oct2 and OBF-1. J Exp Med. 2012;209:2049-64.
    • (2012) J Exp Med. , vol.209 , pp. 2049-2064
    • Karnowski, A.1    Chevrier, S.2    Belz, G.T.3    Mount, A.4    Emslie, D.5    D'Costa, K.6
  • 43
    • 84928128188 scopus 로고    scopus 로고
    • SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis
    • Amador-Arjona A, Cimadamore F, Huang CT, Wright R, Lewis S, Gage FH, et al. SOX2 primes the epigenetic landscape in neural precursors enabling proper gene activation during hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2015;112:E1936-45.
    • (2015) Proc Natl Acad Sci U S A. , vol.112 , pp. E1936-E1945
    • Amador-Arjona, A.1    Cimadamore, F.2    Huang, C.T.3    Wright, R.4    Lewis, S.5    Gage, F.H.6
  • 44
    • 84877887974 scopus 로고    scopus 로고
    • Perturbation of transcription factor Nur77 expression mediated by myocyte enhancer factor 2D (MEF2D) regulates dopaminergic neuron loss in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)
    • Mount MP, Zhang Y, Amini M, Callaghan S, Kulczycki J, Mao Z, et al. Perturbation of transcription factor Nur77 expression mediated by myocyte enhancer factor 2D (MEF2D) regulates dopaminergic neuron loss in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). J Biol Chem. 2013;288:14362-71.
    • (2013) J Biol Chem. , vol.288 , pp. 14362-14371
    • Mount, M.P.1    Zhang, Y.2    Amini, M.3    Callaghan, S.4    Kulczycki, J.5    Mao, Z.6
  • 45
    • 84876313659 scopus 로고    scopus 로고
    • Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity
    • Zang T, Maksimova MA, Cowan CW, Bassel-Duby R, Olson EN, Huber KM. Postsynaptic FMRP bidirectionally regulates excitatory synapses as a function of developmental age and MEF2 activity. Mol Cell Neurosci. 2013;56:39-49.
    • (2013) Mol Cell Neurosci. , vol.56 , pp. 39-49
    • Zang, T.1    Maksimova, M.A.2    Cowan, C.W.3    Bassel-Duby, R.4    Olson, E.N.5    Huber, K.M.6
  • 47
    • 80054737703 scopus 로고    scopus 로고
    • Regulatory elements required for the activation and repression of the protocadherin-alpha gene cluster
    • Kehayova P, Monahan K, Chen W, Maniatis T. Regulatory elements required for the activation and repression of the protocadherin-alpha gene cluster. Proc Natl Acad Sci U S A. 2011;108:17195-200.
    • (2011) Proc Natl Acad Sci U S A. , vol.108 , pp. 17195-17200
    • Kehayova, P.1    Monahan, K.2    Chen, W.3    Maniatis, T.4
  • 48
    • 84877835738 scopus 로고    scopus 로고
    • Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci
    • Shih HY, Krangel MS. Chromatin architecture, CCCTC-binding factor, and V(D)J recombination: managing long-distance relationships at antigen receptor loci. J Immunol. 2013;190:4915-21.
    • (2013) J Immunol. , vol.190 , pp. 4915-4921
    • Shih, H.Y.1    Krangel, M.S.2
  • 49
    • 84901249354 scopus 로고    scopus 로고
    • STAT3, STAT4, NFATc1, and CTCF regulate PD-1 through multiple novel regulatory regions in murine T cells
    • Austin JW, Lu P, Majumder P, Ahmed R, Boss JM. STAT3, STAT4, NFATc1, and CTCF regulate PD-1 through multiple novel regulatory regions in murine T cells. J Immunol. 2014;192:4876-86.
    • (2014) J Immunol. , vol.192 , pp. 4876-4886
    • Austin, J.W.1    Lu, P.2    Majumder, P.3    Ahmed, R.4    Boss, J.M.5
  • 50
    • 84901285464 scopus 로고    scopus 로고
    • CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer
    • Kemp CJ, Moore JM, Moser R, Bernard B, Teater M, Smith LE, et al. CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer. Cell Rep. 2014;7:1020-9.
    • (2014) Cell Rep. , vol.7 , pp. 1020-1029
    • Kemp, C.J.1    Moore, J.M.2    Moser, R.3    Bernard, B.4    Teater, M.5    Smith, L.E.6
  • 51
    • 84355163093 scopus 로고    scopus 로고
    • DNA-binding factors shape the mouse methylome at distal regulatory regions
    • Stadler MB, Murr R, Burger L, Ivanek R, Lienert F, Scholer A, et al. DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature. 2011;480:490-5.
    • (2011) Nature. , vol.480 , pp. 490-495
    • Stadler, M.B.1    Murr, R.2    Burger, L.3    Ivanek, R.4    Lienert, F.5    Scholer, A.6
  • 54
    • 84873288916 scopus 로고    scopus 로고
    • Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1)
    • Xing L, Salas M, Zhang H, Gittler J, Ludwig T, Lin CS, et al. Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1). Mamm Genome. 2013;24:30-43.
    • (2013) Mamm Genome. , vol.24 , pp. 30-43
    • Xing, L.1    Salas, M.2    Zhang, H.3    Gittler, J.4    Ludwig, T.5    Lin, C.S.6
  • 55
    • 33745021935 scopus 로고    scopus 로고
    • Transcriptional dysregulation in Down syndrome: predictions for altered protein complex stoichiometries and post-translational modifications, and consequences for learning/behavior genes ELK, CREB, and the estrogen and glucocorticoid receptors
    • Gardiner K. Transcriptional dysregulation in Down syndrome: predictions for altered protein complex stoichiometries and post-translational modifications, and consequences for learning/behavior genes ELK, CREB, and the estrogen and glucocorticoid receptors. Behav Genet. 2006;36:439-53.
    • (2006) Behav Genet. , vol.36 , pp. 439-453
    • Gardiner, K.1
  • 56
    • 79960146777 scopus 로고    scopus 로고
    • Identification and functional characterization of rare mutations of the neuroligin-2 gene (NLGN2) associated with schizophrenia
    • Sun C, Cheng MC, Qin R, Liao DL, Chen TT, Koong FJ, et al. Identification and functional characterization of rare mutations of the neuroligin-2 gene (NLGN2) associated with schizophrenia. Hum Mol Genet. 2011;20:3042-51.
    • (2011) Hum Mol Genet. , vol.20 , pp. 3042-3051
    • Sun, C.1    Cheng, M.C.2    Qin, R.3    Liao, D.L.4    Chen, T.T.5    Koong, F.J.6
  • 57
    • 84858862046 scopus 로고    scopus 로고
    • 790 Kb microduplication in chromosome band 17p13.1 associated with intellectual disability, afebrile seizures, dysmorphic features, diabetes, and hypothyroidism
    • Belligni EF, Di Gregorio E, Biamino E, Calcia A, Molinatto C, Talarico F, et al. 790 Kb microduplication in chromosome band 17p13.1 associated with intellectual disability, afebrile seizures, dysmorphic features, diabetes, and hypothyroidism. Eur J Med Genet. 2012;55:222-4.
    • (2012) Eur J Med Genet , vol.55 , pp. 222-224
    • Belligni, E.F.1    Gregorio, E.2    Biamino, E.3    Calcia, A.4    Molinatto, C.5    Talarico, F.6
  • 59
    • 15044345461 scopus 로고    scopus 로고
    • Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors
    • Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, Mizutani T, et al. Integral role of IRF-5 in the gene induction programme activated by Toll-like receptors. Nature. 2005;434:243-9.
    • (2005) Nature. , vol.434 , pp. 243-249
    • Takaoka, A.1    Yanai, H.2    Kondo, S.3    Duncan, G.4    Negishi, H.5    Mizutani, T.6
  • 60
    • 84871364639 scopus 로고    scopus 로고
    • Protocadherin clusters and cell adhesion kinase regulate dendrite complexity through Rho GTPase
    • Suo L, Lu H, Ying G, Capecchi MR, Wu Q. Protocadherin clusters and cell adhesion kinase regulate dendrite complexity through Rho GTPase. J Mol Cell Biol. 2012;4:362-76.
    • (2012) J Mol Cell Biol. , vol.4 , pp. 362-376
    • Suo, L.1    Lu, H.2    Ying, G.3    Capecchi, M.R.4    Wu, Q.5
  • 62
    • 69549138638 scopus 로고    scopus 로고
    • Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors
    • Pulvers JN, Huttner WB. Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors. Development. 2009;136:1859-68.
    • (2009) Development. , vol.136 , pp. 1859-1868
    • Pulvers, J.N.1    Huttner, W.B.2
  • 63
    • 84887221030 scopus 로고    scopus 로고
    • Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size
    • Koran ME, Hohman TJ, Meda SA, Thornton-Wells TA. Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size. J Alzheimers Dis. 2014;38:145-54.
    • (2014) J Alzheimers Dis. , vol.38 , pp. 145-154
    • Koran, M.E.1    Hohman, T.J.2    Meda, S.A.3    Thornton-Wells, T.A.4
  • 64
    • 84874628328 scopus 로고    scopus 로고
    • Variants at serotonin transporter and 2A receptor genes predict cooperative behavior differentially according to presence of punishment
    • Schroeder KB, McElreath R, Nettle D. Variants at serotonin transporter and 2A receptor genes predict cooperative behavior differentially according to presence of punishment. Proc Natl Acad Sci U S A. 2013;110:3955-60.
    • (2013) Proc Natl Acad Sci U S A. , vol.110 , pp. 3955-3960
    • Schroeder, K.B.1    McElreath, R.2    Nettle, D.3
  • 65
    • 79960845530 scopus 로고    scopus 로고
    • Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells
    • Hitoshi S, Ishino Y, Kumar A, Jasmine S, Tanaka KF, Kondo T, et al. Mammalian Gcm genes induce Hes5 expression by active DNA demethylation and induce neural stem cells. Nat Neurosci. 2011;14:957-64.
    • (2011) Nat Neurosci. , vol.14 , pp. 957-964
    • Hitoshi, S.1    Ishino, Y.2    Kumar, A.3    Jasmine, S.4    Tanaka, K.F.5    Kondo, T.6
  • 66
    • 79960007644 scopus 로고    scopus 로고
    • The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells
    • Gao Z, Ure K, Ding P, Nashaat M, Yuan L, Ma J, et al. The master negative regulator REST/NRSF controls adult neurogenesis by restraining the neurogenic program in quiescent stem cells. J Neurosci. 2011;31:9772-86.
    • (2011) J Neurosci. , vol.31 , pp. 9772-9786
    • Gao, Z.1    Ure, K.2    Ding, P.3    Nashaat, M.4    Yuan, L.5    Ma, J.6
  • 67
    • 34247511497 scopus 로고    scopus 로고
    • LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons
    • Barnes AP, Lilley BN, Pan YA, Plummer LJ, Powell AW, Raines AN, et al. LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell. 2007;129:549-63.
    • (2007) Cell. , vol.129 , pp. 549-563
    • Barnes, A.P.1    Lilley, B.N.2    Pan, Y.A.3    Plummer, L.J.4    Powell, A.W.5    Raines, A.N.6
  • 68
    • 13644267037 scopus 로고    scopus 로고
    • Mammalian SAD kinases are required for neuronal polarization
    • Kishi M, Pan YA, Crump JG, Sanes JR. Mammalian SAD kinases are required for neuronal polarization. Science. 2005;307:929-32.
    • (2005) Science. , vol.307 , pp. 929-932
    • Kishi, M.1    Pan, Y.A.2    Crump, J.G.3    Sanes, J.R.4
  • 71
    • 0033198715 scopus 로고    scopus 로고
    • Molecular cloning and characterization of the human glycogen synthase kinase-3beta promoter
    • Lau KF, Miller CC, Anderton BH, Shaw PC. Molecular cloning and characterization of the human glycogen synthase kinase-3beta promoter. Genomics. 1999;60:121-8.
    • (1999) Genomics. , vol.60 , pp. 121-128
    • Lau, K.F.1    Miller, C.C.2    Anderton, B.H.3    Shaw, P.C.4
  • 73
    • 84874333456 scopus 로고    scopus 로고
    • Haplotype of single nucleotide polymorphisms in exon 6 of the MZF-1 gene and Alzheimer's disease
    • Porcellini E, Carbone I, Martelli PL, Ianni M, Casadio R, Pession A, et al. Haplotype of single nucleotide polymorphisms in exon 6 of the MZF-1 gene and Alzheimer's disease. J Alzheimers Dis. 2013;34:439-47.
    • (2013) J Alzheimers Dis. , vol.34 , pp. 439-447
    • Porcellini, E.1    Carbone, I.2    Martelli, P.L.3    Ianni, M.4    Casadio, R.5    Pession, A.6
  • 75
    • 84874289247 scopus 로고    scopus 로고
    • Inhibin B and anti-Mullerian hormone/Mullerian-inhibiting substance may contribute to the male bias in autism
    • Pankhurst MW, McLennan IS. Inhibin B and anti-Mullerian hormone/Mullerian-inhibiting substance may contribute to the male bias in autism. Transl Psychiatry. 2012;2, e148.
    • (2012) Transl Psychiatry. , vol.2
    • Pankhurst, M.W.1    McLennan, I.S.2
  • 76
    • 77955294582 scopus 로고    scopus 로고
    • MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence
    • Venkataraman S, Alimova I, Fan R, Harris P, Foreman N, Vibhakar R. MicroRNA 128a increases intracellular ROS level by targeting Bmi-1 and inhibits medulloblastoma cancer cell growth by promoting senescence. PLoS One. 2010;5, e10748.
    • (2010) PLoS One. , vol.5
    • Venkataraman, S.1    Alimova, I.2    Fan, R.3    Harris, P.4    Foreman, N.5    Vibhakar, R.6
  • 77
    • 80051557697 scopus 로고    scopus 로고
    • The male bias in the number of Purkinje cells and the size of the murine cerebellum may require Mullerian inhibiting substance/anti-Mullerian hormone
    • Wittmann W, McLennan IS. The male bias in the number of Purkinje cells and the size of the murine cerebellum may require Mullerian inhibiting substance/anti-Mullerian hormone. J Neuroendocrinol. 2011;23:831-8.
    • (2011) J Neuroendocrinol. , vol.23 , pp. 831-838
    • Wittmann, W.1    McLennan, I.S.2
  • 78
    • 84884145737 scopus 로고    scopus 로고
    • Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model
    • Das I, Park JM, Shin JH, Jeon SK, Lorenzi H, Linden DJ, et al. Hedgehog agonist therapy corrects structural and cognitive deficits in a Down syndrome mouse model. Sci Transl Med. 2013;5:201ra120.
    • (2013) Sci Transl Med. , vol.5 , pp. 201ra120
    • Das, I.1    Park, J.M.2    Shin, J.H.3    Jeon, S.K.4    Lorenzi, H.5    Linden, D.J.6
  • 80
    • 0034015438 scopus 로고    scopus 로고
    • CpG-island methylation in aging and cancer
    • Issa JP. CpG-island methylation in aging and cancer. Curr Top Microbiol Immunol. 2000;249:101-18.
    • (2000) Curr Top Microbiol Immunol. , vol.249 , pp. 101-118
    • Issa, J.P.1
  • 84
    • 77954143021 scopus 로고    scopus 로고
    • Early developmental alterations in GABAergic protein expression in fragile X knockout mice
    • Adusei DC, Pacey LK, Chen D, Hampson DR. Early developmental alterations in GABAergic protein expression in fragile X knockout mice. Neuropharmacology. 2010;59:167-71.
    • (2010) Neuropharmacology. , vol.59 , pp. 167-171
    • Adusei, D.C.1    Pacey, L.K.2    Chen, D.3    Hampson, D.R.4
  • 85
    • 84879152374 scopus 로고    scopus 로고
    • SYNGAP1 links the maturation rate of excitatory synapses to the duration of critical-period synaptic plasticity
    • Clement JP, Ozkan ED, Aceti M, Miller CA, Rumbaugh G. SYNGAP1 links the maturation rate of excitatory synapses to the duration of critical-period synaptic plasticity. J Neurosci. 2013;33:10447-52.
    • (2013) J Neurosci. , vol.33 , pp. 10447-10452
    • Clement, J.P.1    Ozkan, E.D.2    Aceti, M.3    Miller, C.A.4    Rumbaugh, G.5
  • 87
    • 33645453807 scopus 로고    scopus 로고
    • Intellectual ability and cortical development in children and adolescents
    • Shaw P, Greenstein D, Lerch J, Clasen L, Lenroot R, Gogtay N, et al. Intellectual ability and cortical development in children and adolescents. Nature. 2006;440:676-9.
    • (2006) Nature. , vol.440 , pp. 676-679
    • Shaw, P.1    Greenstein, D.2    Lerch, J.3    Clasen, L.4    Lenroot, R.5    Gogtay, N.6
  • 88
    • 84893772144 scopus 로고    scopus 로고
    • Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21
    • Hibaoui Y, Grad I, Letourneau A, Sailani MR, Dahoun S, Santoni FA, et al. Modelling and rescuing neurodevelopmental defect of Down syndrome using induced pluripotent stem cells from monozygotic twins discordant for trisomy 21. EMBO Mol Med. 2014;6:259-77.
    • (2014) EMBO Mol Med. , vol.6 , pp. 259-277
    • Hibaoui, Y.1    Grad, I.2    Letourneau, A.3    Sailani, M.R.4    Dahoun, S.5    Santoni, F.A.6
  • 89
    • 63449086968 scopus 로고    scopus 로고
    • Epigenetic mechanisms in glioblastoma multiforme
    • Nagarajan RP, Costello JF. Epigenetic mechanisms in glioblastoma multiforme. Semin Cancer Biol. 2009;19:188-97.
    • (2009) Semin Cancer Biol. , vol.19 , pp. 188-197
    • Nagarajan, R.P.1    Costello, J.F.2
  • 90
    • 84877299145 scopus 로고    scopus 로고
    • The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
    • Chan KM, Fang D, Gan H, Hashizume R, Yu C, Schroeder M, et al. The histone H3.3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression. Genes Dev. 2013;27:985-90.
    • (2013) Genes Dev , vol.27 , pp. 985-990
    • Chan, K.M.1    Fang, D.2    Gan, H.3    Hashizume, R.4    Yu, C.5    Schroeder, M.6
  • 92
    • 80055115383 scopus 로고    scopus 로고
    • Neuronal nuclei isolation from human postmortem brain tissue
    • Matevossian A, Akbarian S. Neuronal nuclei isolation from human postmortem brain tissue. J Vis E. 2008.
    • (2008) J Vis E
    • Matevossian, A.1    Akbarian, S.2
  • 93
    • 33845432928 scopus 로고    scopus 로고
    • Adjusting batch effects in microarray expression data using empirical Bayes methods
    • Johnson WE, Li C, Rabinovic A. Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics. 2007;8:118-27.
    • (2007) Biostatistics. , vol.8 , pp. 118-127
    • Johnson, W.E.1    Li, C.2    Rabinovic, A.3
  • 94
    • 84875737335 scopus 로고    scopus 로고
    • An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform
    • Marabita F, Almgren M, Lindholm ME, Ruhrmann S, Fagerstrom-Billai F, Jagodic M, et al. An evaluation of analysis pipelines for DNA methylation profiling using the Illumina HumanMethylation450 BeadChip platform. Epigenetics. 2013;8:333-46.
    • (2013) Epigenetics. , vol.8 , pp. 333-346
    • Marabita, F.1    Almgren, M.2    Lindholm, M.E.3    Ruhrmann, S.4    Fagerstrom-Billai, F.5    Jagodic, M.6
  • 95
    • 44249091849 scopus 로고    scopus 로고
    • Automating dChip: toward reproducible sharing of microarray data analysis
    • Li C. Automating dChip: toward reproducible sharing of microarray data analysis. BMC Bioinformatics. 2008;9:231.
    • (2008) BMC Bioinformatics. , vol.9 , pp. 231
    • Li, C.1
  • 96
    • 0036856355 scopus 로고    scopus 로고
    • MethPrimer: designing primers for methylation PCRs
    • Li LC, Dahiya R. MethPrimer: designing primers for methylation PCRs. Bioinformatics. 2002;18:1427-31.
    • (2002) Bioinformatics. , vol.18 , pp. 1427-1431
    • Li, L.C.1    Dahiya, R.2
  • 97
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods. 2001;25:402-8.
    • (2001) Methods. , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 100
    • 84873310426 scopus 로고    scopus 로고
    • Genome-wide chromatin state transitions associated with developmental and environmental cues
    • Zhu J, Adli M, Zou JY, Verstappen G, Coyne M, Zhang X, et al. Genome-wide chromatin state transitions associated with developmental and environmental cues. Cell. 2013;152:642-54.
    • (2013) Cell. , vol.152 , pp. 642-654
    • Zhu, J.1    Adli, M.2    Zou, J.Y.3    Verstappen, G.4    Coyne, M.5    Zhang, X.6
  • 101
    • 80051564877 scopus 로고    scopus 로고
    • Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions
    • Zentner GE, Tesar PJ, Scacheri PC. Epigenetic signatures distinguish multiple classes of enhancers with distinct cellular functions. Genome Res. 2011;21:1273-83.
    • (2011) Genome Res. , vol.21 , pp. 1273-1283
    • Zentner, G.E.1    Tesar, P.J.2    Scacheri, P.C.3
  • 104
    • 79955765058 scopus 로고    scopus 로고
    • DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression
    • Zheng S, Houseman EA, Morrison Z, Wrensch MR, Patoka JS, Ramos C, et al. DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression. Neuro-Oncology. 2011;13:280-9.
    • (2011) Neuro-Oncology. , vol.13 , pp. 280-289
    • Zheng, S.1    Houseman, E.A.2    Morrison, Z.3    Wrensch, M.R.4    Patoka, J.S.5    Ramos, C.6
  • 105
    • 84969423696 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc. 1995;57:289-300.
    • (1995) J R Stat Soc. , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 106
    • 77649197465 scopus 로고    scopus 로고
    • Effect of leucovorin (folinic acid) on the developmental quotient of children with Down's syndrome (trisomy 21) and influence of thyroid status
    • Blehaut H, Mircher C, Ravel A, Conte M, de Portzamparc V, Poret G, et al. Effect of leucovorin (folinic acid) on the developmental quotient of children with Down's syndrome (trisomy 21) and influence of thyroid status. PLoS One. 2010;5, e8394.
    • (2010) PLoS One. , vol.5
    • Blehaut, H.1    Mircher, C.2    Ravel, A.3    Conte, M.4    Portzamparc, V.5    Poret, G.6


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