Early forebrain wiring: Genetic dissection using conditional Celsr3 mutant mice

Science

Volumn 320, Issue 5878, 2008, Pages 946-949

  Zhou, Libing ^a   Bar, Isabelle ^b,h   Achouri, Younès ^a   Campbell, Kenneth ^c   De Backer, Olivier ^b   Hebert, Jean M ^d   Jones, Kevin ^e   Kessaris, Nicoletta ^f   De Rouvroit, Catherine Lambert ^b   O'Leary, Dennis ^g   Richardson, William D ^f   Goffinet, Andre M ^a   Tissir, Fadel ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b UNIVERSITY OF NAMUR   (Belgium)

^c CINCINNATI CHILDREN S HOSPITAL RESEARCH FOUNDATION   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF COLORADO   (United States)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

^g SALK INSTITUTE FOR BIOLOGICAL STUDIES   (United States)

^h UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CYTOLOGY; MAMMAL; MUTATION;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELSR3 GENE; CONTROLLED STUDY; CRANIAL NERVE; DIENCEPHALON; FOREBRAIN; GENE; GENE EXPRESSION; GENE MUTATION; HETEROZYGOSITY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MOUSE; NONHUMAN; OLFACTORY SYSTEM; PRIORITY JOURNAL; TELENCEPHALON; ANIMAL; BRAIN CORTEX; CAPSULA INTERNA; CYTOLOGY; FEMALE; GENE SILENCING; GENETICS; NERVE CELL; NERVE FIBER; NERVE TRACT; PHYSIOLOGY; PRENATAL DEVELOPMENT; SEPTUM NUCLEUS; THALAMUS; TISSUE CULTURE TECHNIQUE;

MAMMALIA; MUS;

CADHERIN; CELL SURFACE RECEPTOR; CELSR3 PROTEIN, MOUSE;

ANIMALS; AXONS; CADHERINS; CEREBRAL CORTEX; FEMALE; GENE SILENCING; INTERNAL CAPSULE; MALE; MICE; NEURAL PATHWAYS; NEURONS; PROSENCEPHALON; RECEPTORS, CELL SURFACE; SEPTAL NUCLEI; THALAMUS; TISSUE CULTURE TECHNIQUES;

EID: 44249105664     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1155244     Document Type: Article

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27. We thank V. Bonte, I. Lambermont, and E. Paitre for technical assistance; G. Hamard for help with embryonic stem cell injections; M. Okabe for GFP mice; F. G. Rathjen for antibodies against L1; P. Soriano for ROSA26R mice; and L. Nguyen, A. Stoykova, and P. Vanderhaeghen for help or discussion. This work was supported by grants Actions de recherches concertées (ARC-186), FRFC 2.4504.01, FRSM 3.4501.07, and FRSM 3.4529.03; by Interuniversity Poles of Attraction (SSTC, PAI p6/20); and by the Fondation Médicale Reine Elisabeth, all from Belgium. F.T. is a Research Associate of the Fonds National de la Recherche Scientifique.