Effect of leucovorin (folinic acid) on the developmental quotient of children with down's syndrome (trisomy 21) and influence of thyroid status

PLoS ONE

Volumn 5, Issue 1, 2010, Pages

  Blehaut, Henri ^a   Mircher, Clotilde ^a   Ravel, Aimé ^a   Conte, Martine ^a   De Portzamparc, Veronique ^a   Poret, Gwendael ^a   De Kermadec, Françoise Huon ^b   Rethore, Marie Odile ^a,c   Sturtz, Franck G ^a,d  

^a Institut Jerome Lejeune   (France)

^b AGROCAMPUS OUEST   (France)

^c Assistance Publique de Paris   (France)

^d UNIVERSITY OF LIMOGES   (France)

Author keywords

[No Author keywords available]

Indexed keywords

FOLINIC ACID; FOLINORAL; PLACEBO; THYROXINE; UNCLASSIFIED DRUG;

ABSENCE OF SIDE EFFECTS; ARTICLE; BRUNET LEZINE SCALE; CHILD; CLINICAL TRIAL; COGNITION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DOWN SYNDROME; DRUG EFFECT; FEMALE; HUMAN; HYPOTHYROIDISM; INFANT; MAJOR CLINICAL STUDY; MALE; MENTAL DEVELOPMENT; PATIENT COMPLIANCE; PRESCHOOL CHILD; PSYCHOMOTOR DEVELOPMENT; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; THYROID GLAND; TREATMENT OUTCOME; VITAMIN SUPPLEMENTATION;

CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; DOWN SYNDROME; FEMALE; HUMANS; INFANT; LEUCOVORIN; MALE; PLACEBOS; THYROID GLAND;

EID: 77649197465     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0008394     Document Type: Article

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