Haplotype of single nucleotide polymorphisms in exon 6 of the MZF-1 gene and Alzheimer's disease

Journal of Alzheimer's Disease

Volumn 34, Issue 2, 2013, Pages 439-447

  Porcellini, Elisa ^a   Carbone, Ilaria ^a   Martelli, Pier Luigi ^a   Ianni, Manuela ^a   Casadio, Rita ^a   Pession, Annalisa ^a   Licastro, Federico ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Alzheimer's disease; gene polymorphisms; MZF 1; transcription factors binding

Indexed keywords

MYELOID ZINC FINGER PROTEIN 1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN;

AGED; ALZHEIMER DISEASE; ARTICLE; BINDING SITE; CONTROLLED STUDY; EXON; FEMALE; GENETIC DATABASE; GENETIC RISK; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN BINDING; SINGLE NUCLEOTIDE POLYMORPHISM; ZINC FINGER MOTIF;

EID: 84874333456     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-121546     Document Type: Article

References (35)

1. Hardy J, Selkoe DJ (2002) The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science 297, 353-356 (Pubitemid 34790756)
2. Gatz M, Reynolds CA, Fratiglioni L, Johansson B, Mortimer JA, Berg S, Fiske A, Pedersen NL (2006) Role of genes and environments for explaining Alzheimer disease. Arch Gen Psychiatry 63, 168-174 (Pubitemid 43213878)
3. Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, SmallGW, Roses AD, Haines JL, Pericak-Vance MA (1993) Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261, 921-923 (Pubitemid 23275809)
4. Lambert JC, Heath S, Even G, Campion D, Sleegers K, Hiltunen M, Combarros O, Zelenika D, Bullido MJ, Tavernier B, Letenneur L, Bettens K, Berr C, Pasquier F, Fi'evet N, Barberger-Gateau P, Engelborghs S, De Deyn P, Mateo I, Franck A, Helisalmi S, Porcellini E, Hanon O, European Alzheimer's Disease Initiative Investigators, de Pancorbo MM, Lendon C, Dufouil C, Jaillard C, Leveillard T, Alvarez V, Bosco P, Mancuso M, Panza F, Nacmias B, Bossù P, Piccardi P, Annoni G, Seripa D, Galimberti D, Hannequin D, Licastro F, Soininen H, Ritchie K, Blanch'e H, Dartigues JF, Tzourio C, Gut I,Van BroeckhovenC, Alp'erovitch A, Lathrop M, Amouyel P (2009) Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 41, 1094-1099
5. Hollingworth P, Harold D, Sims R, Gerrish A, Lambert JC, Carrasquillo MM, Abraham R, Hamshere ML, Pahwa JS, Moskvina V, Dowzell K, Jones N, Stretton A, Thomas C, Richards A, Ivanov D,Widdowson C, Chapman J, Lovestone S, Powell J, Proitsi P, Lupton MK, Brayne C, Rubinsztein DC, Gill M, Lawlor B, Lynch A, Brown KS, Passmore PA, Craig D, McGuinness B, Todd S, Holmes C, Mann D, Smith AD, Beaumont H,Warden D,Wilcock G, Love S, Kehoe PG, Hooper NM, Vardy ER, Hardy J, Mead S, Fox NC, Rossor M, Collinge J, MaierW, Jessen F, Ruther E, Schurmann B, Heun R,Kolsch H, van den Bussche H, Heuser I,Kornhuber J,Wiltfang J, Dichgans M, Frolich L, Hampel H, Gallacher J, Hull M, Rujescu D, Giegling I, Goate AM, Kauwe JS, Cruchaga C, Nowotny P, Morris JC, Mayo K, Sleegers K, Bettens K, Engelborghs S, De Deyn PP, Van Broeckhoven C, Livingston G, Bass NJ, Gurling H, McQuillin A, Gwilliam R, Deloukas P, Al-Chalabi A, Shaw CE, Tsolaki M, Singleton AB, Guerreiro R, Muhleisen TW, Nothen MM, Moebus S, Jockel KH, Klopp N, Wichmann HE, Pankratz VS, Sando SB, Aasly JO, Barcikowska M, Wszolek ZK, Dickson DW, Graff-Radford NR, Petersen RC, Alzheimer's Disease Neuroimaging Initiative, van Duijn CM, Breteler MM, Ikram MA, DeStefano AL, Fitzpatrick AL, Lopez O, Launer LJ, Seshadri S, CHARGE consortium, Berr C, Campion D, Epelbaum J, Dartigues JF, Tzourio C, Alp'erovitch A, Lathrop M, EADI1 consortium, Feulner TM, Friedrich P, Riehle C, Krawczak M, Schreiber S, Mayhaus M, Nicolhaus S, Wagenpfeil S, Steinberg S, Stefansson H, Stefansson K, Snaedal J, Bjornsson S, Jonsson PV, Chouraki V, Genier-Boley B, Hiltunen M, Soininen H, Combarros O, Zelenika D, Delepine M, Bullido MJ, Pasquier F, Mateo I, Frank-Garcia A, Porcellini E, Hanon O, Coto E, Alvarez V, Bosco P, Siciliano G, Mancuso M, Panza F, Solfrizzi V, Nacmias B, Sorbi S, Bossù P, Piccardi P, Arosio B, Annoni G, Seripa D, Pilotto A, Scarpini E, Galimberti D, Brice A, Hannequin D, Licastro F, Jones L, Holmans PA, Jonsson T, Riemenschneider M, Morgan K, Younkin SG, Owen MJ, O'Donovan M, Amouyel P, Williams J (2011) Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet 43, 429-435
6. Licastro F, Porcellini E, Chiappelli M, Forti P, Buscema M, Ravaglia G, Grossi E (2010) Multivariable network associated with cognitive decline and dementia. Neurobiol Aging 31, 257-269
7. Licastro F, Chiappelli M, Grimaldi LM,MorganK, Kalsheker N, Calabrese E, Ritchie A, Porcellini E, Salani G, Franceschi M, Canal N (2005) A new promoter polymorphism in the alpha-1-antichymotrypsin gene is a disease modifier of Alzheimer's disease. Neurobiol Aging 26, 449-453 (Pubitemid 40093928)
8. Furby A, Leys D, Delacourte A, Buee L, Soetaert G, Petit H (1991) Are alpha-1-antichymotrypsin and inter-alpha-trypsin inhibitor peripheral markers of Alzheimer's disease? J Neurol Neurosurg Psychiatry 54, 469
9. Licastro F, Parnetti L, Morini MC, Davis LJ, Cucinotta D, Gaiti A, Senin U (1995) Acute phase reactant alpha 1-antichymotrypsin is increased in cerebrospinal fluid and serum of patients with probable Alzheimer disease. Alzheimer Dis Assoc Disord 9, 112-118
10. Porcellini E, Davis EJ, Chiappelli M, Ianni E, Di Stefano G, Forti P, Ravaglia G, Licastro F (2008) Elevated plasma levels of alpha-1-anti- chymotrypsin in age-related cognitive decline and Alzheimer's disease: A potential therapeutic target. Curr Pharm Des 14, 2659-2664
11. Polvikoski T, Sulkava R, Haltia M, Kainulainen K, Vuorio A, Verkkoniemi A, Niinist?o L, Halonen P, Kontula K (1995) Apolipoprotein E, dementia, and cortical deposition of betaamyloid protein. N Engl J Med 333, 1242-1247
12. Wilson AG, de Vries N, Pociot F, di Giovine FS, van der Putte LB, Duff GW (1993) An allelic polymorphism within the human tumor necrosis factor alpha promoter region is strongly associated with HLA A1, B8, and DR3 alleles. J Exp Med 177, 557-560 (Pubitemid 23117109)
13. Lio D, Annoni G, Licastro F, Crivello A, Forte GI, Scola L, Colonna-Romano G, Candore G, Arosio B, Galimberti L, Vergani C, Caruso C (2006) Tumor necrosis factor-alpha -308A/G polymorphism is associated with age at onset of Alzheimer's disease. Mech Ageing Dev 127, 567-571
14. Strle K, Zhou JH, Shen WH, Broussard SR, Johnson RW, Freund GG, Dantzer R, Kelley KW (2001) Interleukin-10 in the brain. Crit Rev Immunol 21, 427-449 (Pubitemid 34259914)
15. Scassellati C, Zanardini R, Squitti R, Bocchio-Chiavetto L, Bonvicini C, Binetti G, Zanetti O, Cassetta E, Gennarelli M (2004) Promoter haplotypes of interleukin-10 gene and sporadic Alzheimer's disease. Neurosci Lett 356, 119-122 (Pubitemid 38121483)
16. Di Bona D, Rizzo C, Bonaventura G, Candore G, Caruso C (2012) Association between interleukin-10 polymorphisms and Alzheimer's disease: A systematic review and metaanalysis. J Alzheimers Dis 29, 751-759
17. Zhang Y, Zhang J, Tian C, Xiao Y, Li X, He C, Huang J, Fan HJ (2011) The -1082G/A polymorphism in IL-10 gene is associated with risk of Alzheimer's disease: A meta-analysis. Neurol Sci 303, 133-138
18. Porcellini E, Calabrese E, Guerini F, Govoni M, Chiappelli M, Tumini E, Morgan K, Chappell S, Kalsheker N, Franceschi M, Licastro F (2007) The hydroxy-methyl-glutaryl CoA reductase promoter polymorphism is associated with Alzheimer's risk and cognitive deterioration. Neurosci Lett 416, 66-70 (Pubitemid 46437283)
19. Chong PH,Kezele R, FranklinC(2002) High-density lipoprotein cholesterol and the role of statins. Circ J 66, 1037-1044 (Pubitemid 35422676)
20. Kuodinov AR, Berezov TT, Kuodinova NV (1998) Alzheimer's amyloid beta and lipid metabolism: A missing link? FASEB 12, 1097-1099 (Pubitemid 28418939)
21. Campion D, Dumanchin C, Hannequin D, Dubois B, Belliard S, Puel M, Thomas-Anterion C, Michon A, Martin C, Charbonnier F, Raux G, Camuzat A, Penet C, Mesnage V, Martinez M, Clerget-Darpoux F, Brice A, Frebourg T (1999) Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum.Am J Hum Genet 65, 664-670 (Pubitemid 30468710)
22. Matys V, Fricke E, Geffers R, Gossling E, Haubrock M, Hehl R, Hornischer K, Karas D, Kel AE, Kel-Margoulis OV, Kloos DU, Land S, Lewicki-Potapov B, Michael H, Munch R, Reuter I, Rotert S, Saxel H, Scheer M, Thiele S, Wingender E (2003) TRANSFAC: Transcriptional regulation, from patterns to profiles. Nucleic Acids Res 31, 374-378 (Pubitemid 36150406)
23. Sandelin A, Alkema W, Engstr?om P, Wasserman WW, Lenhard B (2004) JASPAR: An open-access database for eukaryotic transcription factor binding profiles Nucleic Acids Res 32(Database issue), D91-D4
24. Schug J (2008) Using TESS to predict transcription factor binding sites in DNA sequence. Curr Protoc Bioinformatics Chapter 2, Unit 2.6
25. Ravaglia G, Forti P, Maioli F, Orlanducci P, Sacchetti L, Flisi E, Dalmonte E, Martignani A, Cucinotta D, Cavalli G (2001) Conselice study: A population based survey of brain aging in a muncipality of the Emilia Romagna region: (A.U.S.L. Ravenna) Design and methods. Arch Gerontol Geriatr Suppl 7, 313-324 (Pubitemid 32727500)
26. McKhann G, Drachman D, Folstein M, Katzman R, Price D, StadlanEM(1984) Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Service Task Force on Alzheimer's Disease. Neurology 349, 939-944 (Pubitemid 14076461)
27. American Psychiatric Association, (1997) Diagnostic and statistical manual of mental disorders: DSM-III-R. 3rd revised ed. American Psychiatric Association, Washington, DC
28. Morris JF, Hromas R, Rauscher FJ 3rd (1994) Characterization of the DNA-binding properties of the myeloid zinc finger protein MFZ1: Two independent DNA-binding domains recognize two DNA consensus sequences with a common G-rich score. Mol Cell Biol 14, 1787-1795
29. Hromas R, Collins SJ, Hickstein D, Raskind W, Deaven LL, O'Hara P, Hagen FS, Kaushansky K (1991) A retinoic acid-responsive human zinc finger gene, MZF-1, preferentially expressed in myeloid cells. J Biol Chem 266, 14183-14187 (Pubitemid 21907481)
30. Bavisotto L, Kaushansky K, Lin N, Hromas R (1991) Antisense oligonucleotides from the stage-specific myeloid zinc finger gene MZF-1 inhibit granulopoiesis in vitro. J Exp Med 174, 1097-1101
31. Perrotti D, Melotti P, Skorski T, Casella I, Peschle C, Calabretta B (1995) Overexpression of the zinc finger protein MZF1 inhibits hematopoietic development from embryonic stem cells: Correlation with negative regulation of CD34 and c-myb promoter activity. Mol Cell Biol 15, 6075-6087
32. Robertson KA, Hill DP, Kelley MR, Tritt R, Crum B, Van Epps S, Srour E, Rice S, Hromas R (1998) The myeloid zinc finger gene (MZF-1) delays retinoic acid-induced apoptosis and differentiation in myeloid leukemia cells. Leukemia 12, 690-698 (Pubitemid 28220821)
33. Baird DM, Kipling D (2004) The extent and significance of telomere loss with age. Ann N Y Acad Sci 1019, 265-268 (Pubitemid 38951317)
34. Rodier F, Kim SH, Nijjar T, Yaswen P, Campisi J (2005) Cancer and aging: The importance of telomeres in genome maintenance. Int J Biochem Cell Biol 37, 977-990 (Pubitemid 40311740)
35. Panossian LA, Porter VR, Valenzuela HF, Zhu X, Reback E, Masterman D, Cummings JL, Effros RB (2003) Telomere shortening in T cells correlates with Alzheimer's disease status. Neurobiol Aging 24, 77-84 (Pubitemid 35454145)