메뉴 건너뛰기




Volumn 91, Issue 11, 2006, Pages 1473-1480

Concomitant aberrant overexpression of RUNX1 and NCAM in regenerating bone marrow of myeloid leukemia of Down's syndrome

Author keywords

Acute myeloid leukemia; Down's syndrome; Leukemogenesis; NCAM; RUNX1

Indexed keywords

CD56 ANTIGEN; NERVE CELL ADHESION MOLECULE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR GATA 1; TRANSCRIPTION FACTOR RUNX1;

EID: 33750950626     PISSN: 03906078     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (20)

References (47)
  • 1
    • 0035412104 scopus 로고    scopus 로고
    • Pattern of malignant disorders in individuals with Down's syndrome
    • Hasle H. Pattern of malignant disorders in individuals with Down's syndrome. Lancet Oncol 2001;2:429-36.
    • (2001) Lancet Oncol , vol.2 , pp. 429-436
    • Hasle, H.1
  • 2
    • 0037325661 scopus 로고    scopus 로고
    • A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases
    • Hasle H, Niemeyer CM, Chessells JM, Baumann I, Bennett JM, Kerndrup G, et al. A pediatric approach to the WHO classification of myelodysplastic and myeloproliferative diseases. Leukemia 2003;17:277-82.
    • (2003) Leukemia , vol.17 , pp. 277-282
    • Hasle, H.1    Niemeyer, C.M.2    Chessells, J.M.3    Baumann, I.4    Bennett, J.M.5    Kerndrup, G.6
  • 3
    • 18944363334 scopus 로고    scopus 로고
    • Immunophenotype of Down's syndrome acute myeloid leukemia and transient myeloproliferative disease differs significantly from other diseases with morphologically identical or similar blasts
    • Langebrake C, Creutzig U, Reinhardt D. Immunophenotype of Down's syndrome acute myeloid leukemia and transient myeloproliferative disease differs significantly from other diseases with morphologically identical or similar blasts. Klin Padiatr 2005;217:126-34.
    • (2005) Klin Padiatr , vol.217 , pp. 126-134
    • Langebrake, C.1    Creutzig, U.2    Reinhardt, D.3
  • 4
    • 0034764037 scopus 로고    scopus 로고
    • Transient myeloproliferative disorder and acute myeloid leukemia in Down syndrome. An immunophenotypic analysis
    • Karandikar NJ, Aquino DB, Mckenna RW, Kroft SH. Transient myeloproliferative disorder and acute myeloid leukemia in Down syndrome. An immunophenotypic analysis. Am J Clin Pathol 2001;116:204-10.
    • (2001) Am J Clin Pathol , vol.116 , pp. 204-210
    • Karandikar, N.J.1    Aquino, D.B.2    Mckenna, R.W.3    Kroft, S.H.4
  • 6
    • 6344281019 scopus 로고    scopus 로고
    • Distinct gene signatures of transient and acute megakaryoblastic leukemia in Down syndrome
    • Lightfoot J, Hitzler JK, Zipursky A, Albert M, Macgregor PF. Distinct gene signatures of transient and acute megakaryoblastic leukemia in Down syndrome. Leukemia 2004;18:1617-23.
    • (2004) Leukemia , vol.18 , pp. 1617-1623
    • Lightfoot, J.1    Hitzler, J.K.2    Zipursky, A.3    Albert, M.4    Macgregor, P.F.5
  • 7
    • 3042636440 scopus 로고    scopus 로고
    • Microarray transcript profiling distinguishes the transient from the acute type of megakaryoblastic leukaemia (M7) in Down's syndrome, revealing FRAME as a specific discriminating marker
    • McElwaine S, Mulligan C, Groet J, Spinelli M, Rinaldi A, Denyer G, et al. Microarray transcript profiling distinguishes the transient from the acute type of megakaryoblastic leukaemia (M7) in Down's syndrome, revealing FRAME as a specific discriminating marker. Br J Haematol 2004;125:729-42.
    • (2004) Br J Haematol , vol.125 , pp. 729-742
    • McElwaine, S.1    Mulligan, C.2    Groet, J.3    Spinelli, M.4    Rinaldi, A.5    Denyer, G.6
  • 8
    • 33344462105 scopus 로고    scopus 로고
    • Transitorisch myeloproliferatives syndrom bei neugeborenen mit Down-Syndrom. Überblick und analyse von 115 patienten aus den AML-BFM-studien und der ESPED-studie
    • Diekamp S, Creutzig U, Reinhardt D, Baumann-Köhler M. Transitorisch myeloproliferatives Syndrom bei Neugeborenen mit Down-Syndrom. Überblick und Analyse von 115 Patienten aus den AML-BFM-Studien und der ESPED-Studie. Monatsschrift Kinderheilkunde 2004;154:162-8.
    • (2004) Monatsschrift Kinderheilkunde , vol.154 , pp. 162-168
    • Diekamp, S.1    Creutzig, U.2    Reinhardt, D.3    Baumann-Köhler, M.4
  • 9
    • 0036098159 scopus 로고    scopus 로고
    • Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome
    • Zwaan CM, Kaspers GJ, Pieters R, Hahlen K, Janka-Schaub GE, van Zantwijk CH, et al. Different drug sensitivity profiles of acute myeloid and lymphoblastic leukemia and normal peripheral blood mononuclear cells in children with and without Down syndrome. Blood 2002;99:245-51.
    • (2002) Blood , vol.99 , pp. 245-251
    • Zwaan, C.M.1    Kaspers, G.J.2    Pieters, R.3    Hahlen, K.4    Janka-Schaub, G.E.5    Van Zantwijk, C.H.6
  • 10
    • 18944404989 scopus 로고    scopus 로고
    • AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity
    • Creutzig U, Reinhardt D, Diekamp S, Dworzak M, Stary J, Zimmermann M. AML patients with Down syndrome have a high cure rate with AML-BFM therapy with reduced dose intensity. Leukemia 2005;19:1355-60.
    • (2005) Leukemia , vol.19 , pp. 1355-1360
    • Creutzig, U.1    Reinhardt, D.2    Diekamp, S.3    Dworzak, M.4    Stary, J.5    Zimmermann, M.6
  • 11
    • 0037906527 scopus 로고    scopus 로고
    • Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder
    • Groet J, McElwaine S, Spinelli M, Rinaldi A, Burtscher I, Mulligan C, et al. Acquired mutations in GATA1 in neonates with Down's syndrome with transient myeloid disorder. Lancet 2003;361:1617-20.
    • (2003) Lancet , vol.361 , pp. 1617-1620
    • Groet, J.1    McElwaine, S.2    Spinelli, M.3    Rinaldi, A.4    Burtscher, I.5    Mulligan, C.6
  • 12
    • 0038142350 scopus 로고    scopus 로고
    • GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome
    • Hitzler JK, Cheung J, Li Y, Scherer SW, Zipursky A. GATA1 mutations in transient leukemia and acute megakaryoblastic leukemia of Down syndrome. Blood 2003;101:4301-4.
    • (2003) Blood , vol.101 , pp. 4301-4304
    • Hitzler, J.K.1    Cheung, J.2    Li, Y.3    Scherer, S.W.4    Zipursky, A.5
  • 14
    • 0042243593 scopus 로고    scopus 로고
    • Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21
    • Rainis L, Bercovich D, Strehl S, Teigler-Schlegel A, Stark B, Trka J, et al. Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21. Blood 2003;102:981-6.
    • (2003) Blood , vol.102 , pp. 981-986
    • Rainis, L.1    Bercovich, D.2    Strehl, S.3    Teigler-Schlegel, A.4    Stark, B.5    Trka, J.6
  • 18
    • 0028285292 scopus 로고
    • Investigation of karyotypic, morphologic and clinical features in patients with acute myeloid leukemia blast cells expressing the neural cell adhesion molecule (CD56)
    • Seymour JF, Pierce SA, Kantarjian HM, Keating MJ, Estey EH. Investigation of karyotypic, morphologic and clinical features in patients with acute myeloid leukemia blast cells expressing the neural cell adhesion molecule (CD56). Leukemia 1994;8:823-6.
    • (1994) Leukemia , vol.8 , pp. 823-826
    • Seymour, J.F.1    Pierce, S.A.2    Kantarjian, H.M.3    Keating, M.J.4    Estey, E.H.5
  • 19
    • 17944381145 scopus 로고    scopus 로고
    • CD56 antigenic expression in acute myeloid leukemia identifies patients with poor clinical prognosis
    • Raspadori D, Damiani D, Lenoci M, Rondelli D, Testoni N, Nardi G, et al. CD56 antigenic expression in acute myeloid leukemia identifies patients with poor clinical prognosis. Leukemia 2001;15:1161-4.
    • (2001) Leukemia , vol.15 , pp. 1161-1164
    • Raspadori, D.1    Damiani, D.2    Lenoci, M.3    Rondelli, D.4    Testoni, N.5    Nardi, G.6
  • 20
    • 0030948676 scopus 로고    scopus 로고
    • Neural cell adhesion molecule (CD56)-positive acute myelogenous leukemia and myelodysplastic and myeloproliferative syndromes
    • Mann KP, DeCastro CM, Liu J, Moore JO, Bigner SH, Traweek ST. Neural cell adhesion molecule (CD56)-positive acute myelogenous leukemia and myelodysplastic and myeloproliferative syndromes. Am J Clin Pathol 1997;107:653-60.
    • (1997) Am J Clin Pathol , vol.107 , pp. 653-660
    • Mann, K.P.1    DeCastro, C.M.2    Liu, J.3    Moore, J.O.4    Bigner, S.H.5    Traweek, S.T.6
  • 21
    • 27144557999 scopus 로고    scopus 로고
    • Neural cell adhesion molecule contributes to hemopoiesis-supporting capacity of stromal cell lines
    • Wang X, Hisha H, Taketani S Inaba M, Li Q, Cui W, et al. Neural cell adhesion molecule contributes to hemopoiesis-supporting capacity of stromal cell lines. Stem Cells 2005;23:1389-99.
    • (2005) Stem Cells , vol.23 , pp. 1389-1399
    • Wang, X.1    Hisha, H.2    Taketani, S.3    Inaba, M.4    Li, Q.5    Cui, W.6
  • 22
    • 0030927824 scopus 로고    scopus 로고
    • A novel transcript encoding an N-terminally truncated AML1/PEBP2 αB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cells
    • Zhang YW, Bae SC, Huang G, Fu YX, Lu J, Ahn MY, et al. A novel transcript encoding an N-terminally truncated AML1/PEBP2 αB protein interferes with transactivation and blocks granulocytic differentiation of 32Dcl3 myeloid cells. Mol Cell Biol 1997;17:4133-45
    • (1997) Mol Cell Biol , vol.17 , pp. 4133-4145
    • Zhang, Y.W.1    Bae, S.C.2    Huang, G.3    Fu, Y.X.4    Lu, J.5    Ahn, M.Y.6
  • 23
    • 0036736555 scopus 로고    scopus 로고
    • Mutation of the AML1/RUNX1 gene in a transient myeloproliferative disorder patient with Down syndrome
    • Taketani T, Taki T, Takita J, Ono R, Horikoshi Y, Kaneko Y, et al. Mutation of the AML1/RUNX1 gene in a transient myeloproliferative disorder patient with Down syndrome. Leukemia 2002;16:1866-7.
    • (2002) Leukemia , vol.16 , pp. 1866-1867
    • Taketani, T.1    Taki, T.2    Takita, J.3    Ono, R.4    Horikoshi, Y.5    Kaneko, Y.6
  • 24
    • 0042522486 scopus 로고    scopus 로고
    • AML1/RUNX1 mutations are infrequent, but related to AML-M0, acquired trisomy 21, and leukemic transformation in pediatric hematologic malignancies
    • Taketani T, Taki T, Takita J, Tsuchida M, Hanada R, Hongo T, et al. AML1/RUNX1 mutations are infrequent, but related to AML-M0, acquired trisomy 21, and leukemic transformation in pediatric hematologic malignancies. Genes Chromosomes Cancer 2003;38:1-7.
    • (2003) Genes Chromosomes Cancer , vol.38 , pp. 1-7
    • Taketani, T.1    Taki, T.2    Takita, J.3    Tsuchida, M.4    Hanada, R.5    Hongo, T.6
  • 25
    • 0030061554 scopus 로고    scopus 로고
    • AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis
    • Okuda T, van Deursen J, Hiebert SW, Grosveld G, Downing JR. AML1, the target of multiple chromosomal translocations in human leukemia, is essential for normal fetal liver hematopoiesis. Cell 1996;84:321-30.
    • (1996) Cell , vol.84 , pp. 321-330
    • Okuda, T.1    Van Deursen, J.2    Hiebert, S.W.3    Grosveld, G.4    Downing, J.R.5
  • 26
    • 2342451948 scopus 로고    scopus 로고
    • AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis
    • Ichikawa M, Asai T, Saito T, Seo S, Yamazaki I, Yamagata T, et al. AML-1 is required for megakaryocytic maturation and lymphocytic differentiation, but not for maintenance of hematopoietic stem cells in adult hematopoiesis. Nat Med 2004;10:299-304.
    • (2004) Nat Med , vol.10 , pp. 299-304
    • Ichikawa, M.1    Asai, T.2    Saito, T.3    Seo, S.4    Yamazaki, I.5    Yamagata, T.6
  • 27
    • 0942287758 scopus 로고    scopus 로고
    • Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome
    • Gurbuxani S, Vyas P, Crispino JD. Recent insights into the mechanisms of myeloid leukemogenesis in Down syndrome. Blood 2004;103:399-406.
    • (2004) Blood , vol.103 , pp. 399-406
    • Gurbuxani, S.1    Vyas, P.2    Crispino, J.D.3
  • 28
    • 33644916915 scopus 로고    scopus 로고
    • Increased dosage of the RUNX1/AML1 gene: A third mode of RUNX leukemia?
    • Osato M, Ito Y. Increased dosage of the RUNX1/AML1 gene: a third mode of RUNX leukemia? Crit Rev Eukaryot Gene Expr 2005;15:217-28.
    • (2005) Crit Rev Eukaryot Gene Expr , vol.15 , pp. 217-228
    • Osato, M.1    Ito, Y.2
  • 29
    • 33744458176 scopus 로고    scopus 로고
    • Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome
    • Xu G, Kanezaki R, Toki T, Watanabe S, Takahashi Y, Terui K, et al. Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome. Leukemia 2006;20:1002-8.
    • (2006) Leukemia , vol.20 , pp. 1002-1008
    • Xu, G.1    Kanezaki, R.2    Toki, T.3    Watanabe, S.4    Takahashi, Y.5    Terui, K.6
  • 30
    • 0038819118 scopus 로고    scopus 로고
    • The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow
    • Bjerregaard MD, Jurlander J, Klausen P, Borregaard N, Cowland JB. The in vivo profile of transcription factors during neutrophil differentiation in human bone marrow. Blood 2003;101:4322-32.
    • (2003) Blood , vol.101 , pp. 4322-4332
    • Bjerregaard, M.D.1    Jurlander, J.2    Klausen, P.3    Borregaard, N.4    Cowland, J.B.5
  • 31
    • 0017162163 scopus 로고
    • Proposals for the classification of the acute leukaemias
    • French-American-British (FAB) co-operative group
    • Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, et al. Proposals for the classification of the acute leukaemias. French-American-British (FAB) co-operative group. Br J Haematol 1976;33:451-8.
    • (1976) Br J Haematol , vol.33 , pp. 451-458
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.T.3    Flandrin, G.4    Galton, D.A.5    Gralnick, H.R.6
  • 32
    • 0022135739 scopus 로고
    • Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group
    • Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, et al. Proposed revised criteria for the classification of acute myeloid leukemia. A report of the French-American-British Cooperative Group. Ann Intern Med 1985;103:620-5.
    • (1985) Ann Intern Med , vol.103 , pp. 620-625
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.T.3    Flandrin, G.4    Galton, D.A.5    Gralnick, H.R.6
  • 33
    • 0021971421 scopus 로고
    • Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7). A report of the French-American-British Cooperative Group
    • Bennett JM, Catovsky D, Daniel MT, Flandrin G, Galton DA, Gralnick HR, et al. Criteria for the diagnosis of acute leukemia of megakaryocyte lineage (M7). A report of the French-American-British Cooperative Group. Ann Intern Med 1985;103:460-2.
    • (1985) Ann Intern Med , vol.103 , pp. 460-462
    • Bennett, J.M.1    Catovsky, D.2    Daniel, M.T.3    Flandrin, G.4    Galton, D.A.5    Gralnick, H.R.6
  • 34
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(ΔΔCT) method
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(ΔΔCT) method. Methods 2001;25:402-8.
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 35
    • 33747066438 scopus 로고    scopus 로고
    • Residual disease monitoring in childhood acute myeloid leukemia by multiparameter flow cytometry: The MRD-AML-BFM study group
    • MRD-AML-BFM Study Group
    • Langebrake C, Creutzig U, Dworzak M, Hrusak O, Mejstrikova E, Griesinger F, et al. Residual disease monitoring in childhood acute myeloid leukemia by multiparameter flow cytometry: the MRD-AML-BFM study group. MRD-AML-BFM Study Group. J Clin Oncol 2006;24:3686-92.
    • (2006) J Clin Oncol , vol.24 , pp. 3686-3692
    • Langebrake, C.1    Creutzig, U.2    Dworzak, M.3    Hrusak, O.4    Mejstrikova, E.5    Griesinger, F.6
  • 36
  • 37
    • 0038579430 scopus 로고    scopus 로고
    • Immunophenotypic evidence of leukemia after induction therapy predicts relapse: Results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia
    • Sievers EL, Lange BJ, Alonzo TA, Gerbing RB, Bernstein ID, Smith FO, et al. Immunophenotypic evidence of leukemia after induction therapy predicts relapse: results from a prospective Children's Cancer Group study of 252 patients with acute myeloid leukemia. Blood 2003;101:3398-406.
    • (2003) Blood , vol.101 , pp. 3398-3406
    • Sievers, E.L.1    Lange, B.J.2    Alonzo, T.A.3    Gerbing, R.B.4    Bernstein, I.D.5    Smith, F.O.6
  • 38
    • 0042425703 scopus 로고    scopus 로고
    • NCAM(CD56) and RUNX1 (AML1) are up-regulated in human ischemic cardiomyopathy and a rat model of chronic cardiac ischemia
    • Gattenlohner S, Waller C, Ertl G, Bultmann BD, Muller-Hermelink HK, Marx A. NCAM(CD56) and RUNX1 (AML1) are up-regulated in human ischemic cardiomyopathy and a rat model of chronic cardiac ischemia. Am J Pathol 2003;163:1081-90.
    • (2003) Am J Pathol , vol.163 , pp. 1081-1090
    • Gattenlohner, S.1    Waller, C.2    Ertl, G.3    Bultmann, B.D.4    Muller-Hermelink, H.K.5    Marx, A.6
  • 39
    • 33644811593 scopus 로고    scopus 로고
    • Increased NCAM expression and vascular development in trisomy 16 mouse embryos: Relationship with nuchal translucency
    • Bekker MN, Arkesteijn JB, van den Akker NM, Hoffman S, Webb S, van Vugt JM, et al. Increased NCAM expression and vascular development in trisomy 16 mouse embryos: relationship with nuchal translucency. Pediatr Res 2005;58:1222-7.
    • (2005) Pediatr Res , vol.58 , pp. 1222-1227
    • Bekker, M.N.1    Arkesteijn, J.B.2    Van Den Akker, N.M.3    Hoffman, S.4    Webb, S.5    Van Vugt, J.M.6
  • 41
    • 0029987146 scopus 로고    scopus 로고
    • Peripheral blood cell counts in infants with Down's syndrome
    • Kivivuori SM, Rajantie J, Siimes MA. Peripheral blood cell counts in infants with Down's syndrome. Clin Genet 1996;49:15-9.
    • (1996) Clin Genet , vol.49 , pp. 15-19
    • Kivivuori, S.M.1    Rajantie, J.2    Siimes, M.A.3
  • 43
    • 0141634051 scopus 로고    scopus 로고
    • Origins of chromosome translocations in childhood leukaemia
    • Greaves MF, Wiemels J. Origins of chromosome translocations in childhood leukaemia. Nat Rev Cancer 2003;3:639-49.
    • (2003) Nat Rev Cancer , vol.3 , pp. 639-649
    • Greaves, M.F.1    Wiemels, J.2
  • 45
    • 0030789242 scopus 로고    scopus 로고
    • Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
    • Bonnet D, Dick JE. Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 1997;3:730-7.
    • (1997) Nat Med , vol.3 , pp. 730-737
    • Bonnet, D.1    Dick, J.E.2
  • 46
    • 33750960386 scopus 로고    scopus 로고
    • Molecular origin of childhood acute myeloid leukemia
    • Reinhardt D, Puhlmann U, Langebrake C. Molecular origin of childhood acute myeloid leukemia. Ann Hematol 2006;85:92-6.
    • (2006) Ann Hematol , vol.85 , pp. 92-96
    • Reinhardt, D.1    Puhlmann, U.2    Langebrake, C.3
  • 47
    • 0034890863 scopus 로고    scopus 로고
    • Hematologic malignancies
    • Gilliland DG. Hematologic malignancies. Curr Opin Hematol 2001;8:189-91.
    • (2001) Curr Opin Hematol , vol.8 , pp. 189-191
    • Gilliland, D.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.