메뉴 건너뛰기




Volumn 117, Issue , 2016, Pages 113-139

Frizzled Receptors in Development and Disease

Author keywords

Angiogenesis; Axon guidance; Blood brain barrier; Hair follicles; Planar cell polarity; Tissue polarity

Indexed keywords

FRIZZLED PROTEIN;

EID: 84955589821     PISSN: 00702153     EISSN: None     Source Type: Book Series    
DOI: 10.1016/bs.ctdb.2015.11.028     Document Type: Chapter
Times cited : (105)

References (121)
  • 3
    • 12344296412 scopus 로고    scopus 로고
    • Mathematical modeling of planar cell polarity to understand domineering nonautonomy
    • Amonlirdviman, K., Khare, N.A., Tree, D.R., Chen, W.S., Axelrod, J.D., Tomlin, C.J., Mathematical modeling of planar cell polarity to understand domineering nonautonomy. Science 307:5708 (2005), 423–426.
    • (2005) Science , vol.307 , Issue.5708 , pp. 423-426
    • Amonlirdviman, K.1    Khare, N.A.2    Tree, D.R.3    Chen, W.S.4    Axelrod, J.D.5    Tomlin, C.J.6
  • 5
    • 79951815612 scopus 로고    scopus 로고
    • Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development
    • Armstrong, A., Ryu, Y.K., Chieco, D., Kuruvilla, R., Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development. The Journal of Neuroscience 31:7 (2011), 2371–2381.
    • (2011) The Journal of Neuroscience , vol.31 , Issue.7 , pp. 2371-2381
    • Armstrong, A.1    Ryu, Y.K.2    Chieco, D.3    Kuruvilla, R.4
  • 6
    • 77951653496 scopus 로고    scopus 로고
    • Epidemiologic and genetic aspects of spina bifida and other neural tube defects
    • Au, K.S., Ashley-Koch, A., Northrup, H., Epidemiologic and genetic aspects of spina bifida and other neural tube defects. Developmental Disabilities Research Reviews 16:1 (2010), 6–15.
    • (2010) Developmental Disabilities Research Reviews , vol.16 , Issue.1 , pp. 6-15
    • Au, K.S.1    Ashley-Koch, A.2    Northrup, H.3
  • 8
    • 0003690716 scopus 로고    scopus 로고
    • The self-made tapestry: Pattern formation in nature
    • Oxford University Press Oxford 287 pp
    • Ball, P., The self-made tapestry: Pattern formation in nature. 1999, Oxford University Press, Oxford 287 pp.
    • (1999)
    • Ball, P.1
  • 9
    • 84873558051 scopus 로고    scopus 로고
    • Wnt signaling in bone homeostasis and disease: From human mutations to treatments
    • Baron, R., Kneissel, M., Wnt signaling in bone homeostasis and disease: From human mutations to treatments. Nature Medicine 19:2 (2013), 179–192.
    • (2013) Nature Medicine , vol.19 , Issue.2 , pp. 179-192
    • Baron, R.1    Kneissel, M.2
  • 11
    • 1642633294 scopus 로고    scopus 로고
    • Norrie disease
    • C.R. Scriver A.L. Beaudet W.S. Sly D. Valle McGraw-Hill New York, NY, USA
    • Berger, W., Ropers, H., Norrie disease. Scriver, C.R., Beaudet, A.L., Sly, W.S., Valle, D., (eds.) The metabolic and molecular bases of inherited disease, 2001, McGraw-Hill, New York, NY, USA, 5977–5985.
    • (2001) The metabolic and molecular bases of inherited disease , pp. 5977-5985
    • Berger, W.1    Ropers, H.2
  • 12
    • 0029994517 scopus 로고    scopus 로고
    • A new member of the frizzled family from drosophila functions as a wingless receptor
    • Bhanot, P., Brink, M., Samos, C.H., Hsieh, J.C., Wang, Y., Macke, J.P., et al. A new member of the frizzled family from drosophila functions as a wingless receptor. Nature 382:6588 (1996), 225–230.
    • (1996) Nature , vol.382 , Issue.6588 , pp. 225-230
    • Bhanot, P.1    Brink, M.2    Samos, C.H.3    Hsieh, J.C.4    Wang, Y.5    Macke, J.P.6
  • 13
    • 0032588683 scopus 로고    scopus 로고
    • Frizzled and frizzled-2 function as redundant receptors for wingless during drosophila embryonic development
    • Bhanot, P., Fish, M., Jemison, J.A., Nusse, R., Nathans, J., Cadigan, K.M., Frizzled and frizzled-2 function as redundant receptors for wingless during drosophila embryonic development. Development 126:18 (1999), 4175–4186.
    • (1999) Development , vol.126 , Issue.18 , pp. 4175-4186
    • Bhanot, P.1    Fish, M.2    Jemison, J.A.3    Nusse, R.4    Nathans, J.5    Cadigan, K.M.6
  • 14
    • 0032434512 scopus 로고    scopus 로고
    • Frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to wingless in neurogenesis
    • Bhat, K.M., Frizzled and frizzled 2 play a partially redundant role in wingless signaling and have similar requirements to wingless in neurogenesis. Cell 95:7 (1998), 1027–1036.
    • (1998) Cell , vol.95 , Issue.7 , pp. 1027-1036
    • Bhat, K.M.1
  • 15
    • 84924063792 scopus 로고    scopus 로고
    • Palatogenesis and cutaneous repair: A two-headed coin
    • Biggs, L.C., Goudy, S.L., Dunnwald, M., Palatogenesis and cutaneous repair: A two-headed coin. Developmental Dynamics 244:3 (2015), 289–310.
    • (2015) Developmental Dynamics , vol.244 , Issue.3 , pp. 289-310
    • Biggs, L.C.1    Goudy, S.L.2    Dunnwald, M.3
  • 18
    • 0026476157 scopus 로고
    • Two homologs of the drosophila polarity gene frizzled (fz) are widely expressed in mammalian tissues
    • Chan, S.D., Karpf, D.B., Fowlkes, M.E., Hooks, M., Bradley, M.S., Vuong, V., et al. Two homologs of the drosophila polarity gene frizzled (fz) are widely expressed in mammalian tissues. The Journal of Biological Chemistry 267:35 (1992), 25202–25207.
    • (1992) The Journal of Biological Chemistry , vol.267 , Issue.35 , pp. 25202-25207
    • Chan, S.D.1    Karpf, D.B.2    Fowlkes, M.E.3    Hooks, M.4    Bradley, M.S.5    Vuong, V.6
  • 19
    • 85016043869 scopus 로고    scopus 로고
    • Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan
    • Chang, T.H., Hsieh, F.L., Zebisch, M., Harlos, K., Elegheert, J., Jones, E.Y., Structure and functional properties of Norrin mimic Wnt for signalling with Frizzled4, Lrp5/6, and proteoglycan. eLife, 4, 2015, 10.7554/eLife.06554.
    • (2015) eLife , vol.4
    • Chang, T.H.1    Hsieh, F.L.2    Zebisch, M.3    Harlos, K.4    Elegheert, J.5    Jones, E.Y.6
  • 22
    • 4243148622 scopus 로고    scopus 로고
    • Sprouty proteins regulate ureteric branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf and stromal Fgf7 signalling during kidney development
    • Chi, L., Zhang, S., Lin, Y., Prunskaite-Hyyrylainen, R., Vuolteenaho, R., Itaranta, P., et al. Sprouty proteins regulate ureteric branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf and stromal Fgf7 signalling during kidney development. Development 131:14 (2004), 3345–3356.
    • (2004) Development , vol.131 , Issue.14 , pp. 3345-3356
    • Chi, L.1    Zhang, S.2    Lin, Y.3    Prunskaite-Hyyrylainen, R.4    Vuolteenaho, R.5    Itaranta, P.6
  • 25
    • 10744227509 scopus 로고    scopus 로고
    • Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse
    • Curtin, J.A., Quint, E., Tsipouri, V., Arkell, R.M., Cattanach, B., Copp, A.J., et al. Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse. Current Biology 13:13 (2003), 1129–1133.
    • (2003) Current Biology , vol.13 , Issue.13 , pp. 1129-1133
    • Curtin, J.A.1    Quint, E.2    Tsipouri, V.3    Arkell, R.M.4    Cattanach, B.5    Copp, A.J.6
  • 29
    • 55549083477 scopus 로고    scopus 로고
    • Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles
    • Devenport, D., Fuchs, E., Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nature Cell Biology 10:11 (2008), 1257–1268.
    • (2008) Nature Cell Biology , vol.10 , Issue.11 , pp. 1257-1268
    • Devenport, D.1    Fuchs, E.2
  • 31
    • 0004224745 scopus 로고
    • System of ophthalmology: Normal and abnormal development
    • C.V. Mosby St. Louis (pp. 764–770).
    • Duke-Elder, S., System of ophthalmology: Normal and abnormal development. 1964, C.V. Mosby, St. Louis, 764–770 (pp. 764–770).
    • (1964) , pp. 764-770
    • Duke-Elder, S.1
  • 32
    • 78649439497 scopus 로고    scopus 로고
    • Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem
    • Fenstermaker, A.G., Prasad, A.A., Bechara, A., Adolfs, Y., Tissir, F., Goffinet, A., et al. Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem. The Journal of Neuroscience 30:47 (2010), 16053–16064.
    • (2010) The Journal of Neuroscience , vol.30 , Issue.47 , pp. 16053-16064
    • Fenstermaker, A.G.1    Prasad, A.A.2    Bechara, A.3    Adolfs, Y.4    Tissir, F.5    Goffinet, A.6
  • 34
    • 33947330375 scopus 로고    scopus 로고
    • Development of the retinal vasculature
    • Fruttiger, M., Development of the retinal vasculature. Angiogenesis 10:2 (2007), 77–88.
    • (2007) Angiogenesis , vol.10 , Issue.2 , pp. 77-88
    • Fruttiger, M.1
  • 35
    • 0030785316 scopus 로고    scopus 로고
    • Persistent fetal vasculature (PFV): An integrated interpretation of signs and symptoms associated with persistent hyperplastic primary vitreous (PHPV). LIV Edward Jackson Memorial Lecture
    • Goldberg, M.F., Persistent fetal vasculature (PFV): An integrated interpretation of signs and symptoms associated with persistent hyperplastic primary vitreous (PHPV). LIV Edward Jackson Memorial Lecture. American Journal of Ophthalmology 124:5 (1997), 587–626.
    • (1997) American Journal of Ophthalmology , vol.124 , Issue.5 , pp. 587-626
    • Goldberg, M.F.1
  • 36
    • 79955565085 scopus 로고    scopus 로고
    • Principles of planar polarity in animal development
    • Goodrich, L.V., Strutt, D., Principles of planar polarity in animal development. Development 138:10 (2011), 1877–1892.
    • (2011) Development , vol.138 , Issue.10 , pp. 1877-1892
    • Goodrich, L.V.1    Strutt, D.2
  • 37
    • 0020004250 scopus 로고
    • A genetic analysis of the determination of cuticular polarity during development in Drosophila melanogaster
    • Gubb, D., Garcia-Bellido, A., A genetic analysis of the determination of cuticular polarity during development in Drosophila melanogaster. Journal of Embryology and Experimental Morphology 68 (1982), 37–57.
    • (1982) Journal of Embryology and Experimental Morphology , vol.68 , pp. 37-57
    • Gubb, D.1    Garcia-Bellido, A.2
  • 39
    • 84860765166 scopus 로고    scopus 로고
    • ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
    • Hao, H.X., Xie, Y., Zhang, Y., Charlat, O., Oster, E., Avello, M., et al. ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. Nature 485:7397 (2012), 195–200.
    • (2012) Nature , vol.485 , Issue.7397 , pp. 195-200
    • Hao, H.X.1    Xie, Y.2    Zhang, Y.3    Charlat, O.4    Oster, E.5    Avello, M.6
  • 40
    • 84894109737 scopus 로고    scopus 로고
    • The Wnt serpentine receptor frizzled-9 regulates new bone formation in fracture healing
    • Heilmann, A., Schinke, T., Bindl, R., Wehner, T., Rapp, A., Haffner-Luntzer, M., et al. The Wnt serpentine receptor frizzled-9 regulates new bone formation in fracture healing. PloS One, 8(12), 2013, e84232.
    • (2013) PloS One , vol.8 , Issue.12 , pp. e84232
    • Heilmann, A.1    Schinke, T.2    Bindl, R.3    Wehner, T.4    Rapp, A.5    Haffner-Luntzer, M.6
  • 42
    • 84908093886 scopus 로고    scopus 로고
    • Partial interchangeability of Fz3 and Fz6 in tissue polarity signaling for epithelial orientation and axon growth and guidance
    • Hua, Z.L., Chang, H., Wang, Y., Smallwood, P.M., Nathans, J., Partial interchangeability of Fz3 and Fz6 in tissue polarity signaling for epithelial orientation and axon growth and guidance. Development 141:20 (2014), 3944–3954.
    • (2014) Development , vol.141 , Issue.20 , pp. 3944-3954
    • Hua, Z.L.1    Chang, H.2    Wang, Y.3    Smallwood, P.M.4    Nathans, J.5
  • 44
    • 84890504424 scopus 로고    scopus 로고
    • Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons
    • Hua, Z.L., Smallwood, P.M., Nathans, J., Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons. eLife, 2, 2013, e01482.
    • (2013) eLife , vol.2 , pp. e01482
    • Hua, Z.L.1    Smallwood, P.M.2    Nathans, J.3
  • 45
    • 0035155579 scopus 로고    scopus 로고
    • Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis
    • Ishikawa, T., Tamai, Y., Zorn, A.M., Yoshida, H., Seldin, M.F., Nishikawa, S., et al. Mouse Wnt receptor gene Fzd5 is essential for yolk sac and placental angiogenesis. Development 128:1 (2001), 25–33.
    • (2001) Development , vol.128 , Issue.1 , pp. 25-33
    • Ishikawa, T.1    Tamai, Y.2    Zorn, A.M.3    Yoshida, H.4    Seldin, M.F.5    Nishikawa, S.6
  • 46
    • 84863543371 scopus 로고    scopus 로고
    • Structural basis of Wnt recognition by Frizzled
    • Janda, C.Y., Waghray, D., Levin, A.M., Thomas, C., Garcia, K.C., Structural basis of Wnt recognition by Frizzled. Science 337:6090 (2012), 59–64.
    • (2012) Science , vol.337 , Issue.6090 , pp. 59-64
    • Janda, C.Y.1    Waghray, D.2    Levin, A.M.3    Thomas, C.4    Garcia, K.C.5
  • 48
    • 70349838225 scopus 로고    scopus 로고
    • TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling
    • Junge, H.J., Yang, S., Burton, J.B., Paes, K., Shu, X., French, D.M., et al. TSPAN12 regulates retinal vascular development by promoting Norrin- but not Wnt-induced FZD4/beta-catenin signaling. Cell 139:2 (2009), 299–311.
    • (2009) Cell , vol.139 , Issue.2 , pp. 299-311
    • Junge, H.J.1    Yang, S.2    Burton, J.B.3    Paes, K.4    Shu, X.5    French, D.M.6
  • 49
    • 84887108773 scopus 로고    scopus 로고
    • Structure and function of norrin in assembly and activation of a frizzled 4-Lrp5/6 complex
    • Ke, J., Harikumar, K.G., Erice, C., Chen, C., Gu, X., Wang, L., et al. Structure and function of norrin in assembly and activation of a frizzled 4-Lrp5/6 complex. Genes & Development 27:21 (2013), 2305–2319.
    • (2013) Genes & Development , vol.27 , Issue.21 , pp. 2305-2319
    • Ke, J.1    Harikumar, K.G.2    Erice, C.3    Chen, C.4    Gu, X.5    Wang, L.6
  • 53
    • 0034931874 scopus 로고    scopus 로고
    • Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant loop-tail
    • Kibar, Z., Vogan, K.J., Groulx, N., Justice, M.J., Underhill, D.A., Gros, P., Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant loop-tail. Nature Genetics 28:3 (2001), 251–255.
    • (2001) Nature Genetics , vol.28 , Issue.3 , pp. 251-255
    • Kibar, Z.1    Vogan, K.J.2    Groulx, N.3    Justice, M.J.4    Underhill, D.A.5    Gros, P.6
  • 55
    • 84865517676 scopus 로고    scopus 로고
    • Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors
    • Koo, B.K., Spit, M., Jordens, I., Low, T.Y., Stange, D.E., van de Wetering, M., et al. Tumour suppressor RNF43 is a stem-cell E3 ligase that induces endocytosis of Wnt receptors. Nature 488:7413 (2012), 665–669.
    • (2012) Nature , vol.488 , Issue.7413 , pp. 665-669
    • Koo, B.K.1    Spit, M.2    Jordens, I.3    Low, T.Y.4    Stange, D.E.5    van de Wetering, M.6
  • 56
    • 78149399666 scopus 로고    scopus 로고
    • Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124
    • Kuhnert, F., Mancuso, M.R., Shamloo, A., Wang, H.T., Choksi, V., Florek, M., et al. Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124. Science 330:6006 (2010), 985–989.
    • (2010) Science , vol.330 , Issue.6006 , pp. 985-989
    • Kuhnert, F.1    Mancuso, M.R.2    Shamloo, A.3    Wang, H.T.4    Choksi, V.5    Florek, M.6
  • 57
    • 0000995797 scopus 로고
    • Gradients in the insect segment: The orientation of hairs in the milkweed bug Oncopeltus fasciatus
    • Lawrence, P.A., Gradients in the insect segment: The orientation of hairs in the milkweed bug Oncopeltus fasciatus. The Journal of Experimental Biology 44 (1966), 607–620.
    • (1966) The Journal of Experimental Biology , vol.44 , pp. 607-620
    • Lawrence, P.A.1
  • 59
    • 0042131956 scopus 로고    scopus 로고
    • A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor
    • Liu, G., Bafico, A., Harris, V.K., Aaronson, S.A., A novel mechanism for Wnt activation of canonical signaling through the LRP6 receptor. Molecular and Cellular Biology 23:16 (2003), 5825–5835.
    • (2003) Molecular and Cellular Biology , vol.23 , Issue.16 , pp. 5825-5835
    • Liu, G.1    Bafico, A.2    Harris, V.K.3    Aaronson, S.A.4
  • 60
    • 84859227651 scopus 로고    scopus 로고
    • Regulation of retinal progenitor expansion by frizzled receptors: Implications for microphthalmia and retinal coloboma
    • Liu, C., Bakeri, H., Li, T., Swaroop, A., Regulation of retinal progenitor expansion by frizzled receptors: Implications for microphthalmia and retinal coloboma. Human Molecular Genetics 21:8 (2012), 1848–1860.
    • (2012) Human Molecular Genetics , vol.21 , Issue.8 , pp. 1848-1860
    • Liu, C.1    Bakeri, H.2    Li, T.3    Swaroop, A.4
  • 61
    • 58149357540 scopus 로고    scopus 로고
    • An essential role for frizzled 5 in mammalian ocular development
    • Liu, C., Nathans, J., An essential role for frizzled 5 in mammalian ocular development. Development 135:21 (2008), 3567–3576.
    • (2008) Development , vol.135 , Issue.21 , pp. 3567-3576
    • Liu, C.1    Nathans, J.2
  • 62
    • 45949098158 scopus 로고    scopus 로고
    • An essential role for Frizzled5 in neuronal survival in the parafascicular nucleus of the thalamus
    • Liu, C., Wang, Y., Smallwood, P.M., Nathans, J., An essential role for Frizzled5 in neuronal survival in the parafascicular nucleus of the thalamus. The Journal of Neuroscience 28:22 (2008), 5641–5653.
    • (2008) The Journal of Neuroscience , vol.28 , Issue.22 , pp. 5641-5653
    • Liu, C.1    Wang, Y.2    Smallwood, P.M.3    Nathans, J.4
  • 63
    • 0000811684 scopus 로고
    • The cuticular pattern in an insect Rhodnius prolixus Stal
    • Locke, M., The cuticular pattern in an insect Rhodnius prolixus Stal. The Journal of Experimental Biology 36 (1959), 459–477.
    • (1959) The Journal of Experimental Biology , vol.36 , pp. 459-477
    • Locke, M.1
  • 64
    • 27244446782 scopus 로고    scopus 로고
    • Role of the Norrie disease pseudoglioma gene in sprouting angiogenesis during development of the retinal vasculature
    • Luhmann, U.F., Lin, J., Acar, N., Lammel, S., Feil, S., Grimm, C., et al. Role of the Norrie disease pseudoglioma gene in sprouting angiogenesis during development of the retinal vasculature. Investigative Ophthalmology & Visual Science 46:9 (2005), 3372–3382.
    • (2005) Investigative Ophthalmology & Visual Science , vol.46 , Issue.9 , pp. 3372-3382
    • Luhmann, U.F.1    Lin, J.2    Acar, N.3    Lammel, S.4    Feil, S.5    Grimm, C.6
  • 65
    • 0348017150 scopus 로고    scopus 로고
    • Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling
    • Lyuksyutova, A.I., Lu, C.C., Milanesio, N., King, L.A., Guo, N., Wang, Y., et al. Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling. Science 302:5652 (2003), 1984–1988.
    • (2003) Science , vol.302 , Issue.5652 , pp. 1984-1988
    • Lyuksyutova, A.I.1    Lu, C.C.2    Milanesio, N.3    King, L.A.4    Guo, N.5    Wang, Y.6
  • 66
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • MacDonald, B.T., Tamai, K., He, X., Wnt/beta-catenin signaling: Components, mechanisms, and diseases. Developmental Cell 17:1 (2009), 9–26.
    • (2009) Developmental Cell , vol.17 , Issue.1 , pp. 9-26
    • MacDonald, B.T.1    Tamai, K.2    He, X.3
  • 67
    • 0043172526 scopus 로고    scopus 로고
    • Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development
    • Majumdar, A., Vainio, S., Kispert, A., McMahon, J., McMahon, A.P., Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. Development 130:14 (2003), 3175–3185.
    • (2003) Development , vol.130 , Issue.14 , pp. 3175-3185
    • Majumdar, A.1    Vainio, S.2    Kispert, A.3    McMahon, J.4    McMahon, A.P.5
  • 69
    • 0033040240 scopus 로고    scopus 로고
    • Wingless signaling in the Drosophila embryo: Zygotic requirements and the role of the frizzled genes
    • Muller, H.A., Samanta, R., Wieschaus, E., Wingless signaling in the Drosophila embryo: Zygotic requirements and the role of the frizzled genes. Development 126:3 (1999), 577–586.
    • (1999) Development , vol.126 , Issue.3 , pp. 577-586
    • Muller, H.A.1    Samanta, R.2    Wieschaus, E.3
  • 70
    • 0035888642 scopus 로고    scopus 로고
    • Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification
    • Murdoch, J.N., Doudney, K., Paternotte, C., Copp, A.J., Stanier, P., Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification. Human Molecular Genetics 10:22 (2001), 2593–2601.
    • (2001) Human Molecular Genetics , vol.10 , Issue.22 , pp. 2593-2601
    • Murdoch, J.N.1    Doudney, K.2    Paternotte, C.3    Copp, A.J.4    Stanier, P.5
  • 72
    • 76049123494 scopus 로고    scopus 로고
    • Next-generation sequencing of a 40 Mb linkage interval reveals TSPAN12 mutations in patients with familial exudative vitreoretinopathy
    • Nikopoulos, K., Gilissen, C., Hoischen, A., van Nouhuys, C.E., Boonstra, F.N., Blokland, E.A., et al. Next-generation sequencing of a 40 Mb linkage interval reveals TSPAN12 mutations in patients with familial exudative vitreoretinopathy. American Journal of Human Genetics 86:2 (2010), 240–247.
    • (2010) American Journal of Human Genetics , vol.86 , Issue.2 , pp. 240-247
    • Nikopoulos, K.1    Gilissen, C.2    Hoischen, A.3    van Nouhuys, C.E.4    Boonstra, F.N.5    Blokland, E.A.6
  • 73
    • 77952703976 scopus 로고    scopus 로고
    • Overview of the mutation spectrum in familial exudative vitreoretinopathy and norrie disease with identification of 21 novel variants in FZD4, LRP5, and NDP
    • Nikopoulos, K., Venselaar, H., Collin, R.W., Riveiro-Alvarez, R., Boonstra, F.N., Hooymans, J.M., et al. Overview of the mutation spectrum in familial exudative vitreoretinopathy and norrie disease with identification of 21 novel variants in FZD4, LRP5, and NDP. Human Mutation 31:6 (2010), 656–666.
    • (2010) Human Mutation , vol.31 , Issue.6 , pp. 656-666
    • Nikopoulos, K.1    Venselaar, H.2    Collin, R.W.3    Riveiro-Alvarez, R.4    Boonstra, F.N.5    Hooymans, J.M.6
  • 75
    • 84920917936 scopus 로고    scopus 로고
    • GPR124 functions as a Wnt7-specific coactivator of canonical beta-catenin signaling
    • Posokhova, E., Shukla, A., Seaman, S., Volate, S., Hilton, M.B., Wu, B., et al. GPR124 functions as a Wnt7-specific coactivator of canonical beta-catenin signaling. Cell Reports 10:2 (2015), 123–130.
    • (2015) Cell Reports , vol.10 , Issue.2 , pp. 123-130
    • Posokhova, E.1    Shukla, A.2    Seaman, S.3    Volate, S.4    Hilton, M.B.5    Wu, B.6
  • 78
    • 22844443861 scopus 로고    scopus 로고
    • Complexity of the genotype-phenotype correlation in familial exudative vitreoretinopathy with mutations in the LRP5 and/or FZD4 genes
    • Qin, M., Hayashi, H., Oshima, K., Tahira, T., Hayashi, K., Kondo, H., Complexity of the genotype-phenotype correlation in familial exudative vitreoretinopathy with mutations in the LRP5 and/or FZD4 genes. Human Mutation 26:2 (2005), 104–112.
    • (2005) Human Mutation , vol.26 , Issue.2 , pp. 104-112
    • Qin, M.1    Hayashi, H.2    Oshima, K.3    Tahira, T.4    Hayashi, K.5    Kondo, H.6
  • 79
    • 77954748533 scopus 로고    scopus 로고
    • Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice
    • Qu, Y., Glasco, D.M., Zhou, L., Sawant, A., Ravni, A., Fritzsch, B., et al. Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice. The Journal of Neuroscience 30:28 (2010), 9392–9401.
    • (2010) The Journal of Neuroscience , vol.30 , Issue.28 , pp. 9392-9401
    • Qu, Y.1    Glasco, D.M.2    Zhou, L.3    Sawant, A.4    Ravni, A.5    Fritzsch, B.6
  • 80
    • 15244345063 scopus 로고    scopus 로고
    • Frizzled 9 knock-out mice have abnormal B-cell development
    • Ranheim, E.A., Kwan, H.C., Reya, T., Wang, Y.K., Weissman, I.L., Francke, U., Frizzled 9 knock-out mice have abnormal B-cell development. Blood 105:6 (2005), 2487–2494.
    • (2005) Blood , vol.105 , Issue.6 , pp. 2487-2494
    • Ranheim, E.A.1    Kwan, H.C.2    Reya, T.3    Wang, Y.K.4    Weissman, I.L.5    Francke, U.6
  • 81
    • 70349157719 scopus 로고    scopus 로고
    • Planar cell polarity cadherin Celsr1 regulates skin hair patterning in the mouse
    • Ravni, A., Qu, Y., Goffinet, A.M., Tissir, F., Planar cell polarity cadherin Celsr1 regulates skin hair patterning in the mouse. The Journal of Investigative Dermatology 129:10 (2009), 2507–2509.
    • (2009) The Journal of Investigative Dermatology , vol.129 , Issue.10 , pp. 2507-2509
    • Ravni, A.1    Qu, Y.2    Goffinet, A.M.3    Tissir, F.4
  • 83
    • 0036789449 scopus 로고    scopus 로고
    • Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy
    • Robitaille, J., MacDonald, M.L., Kaykas, A., Sheldahl, L.C., Zeisler, J., Dube, M.P., et al. Mutant frizzled-4 disrupts retinal angiogenesis in familial exudative vitreoretinopathy. Nature Genetics 32:2 (2002), 326–330.
    • (2002) Nature Genetics , vol.32 , Issue.2 , pp. 326-330
    • Robitaille, J.1    MacDonald, M.L.2    Kaykas, A.3    Sheldahl, L.C.4    Zeisler, J.5    Dube, M.P.6
  • 85
    • 84925337217 scopus 로고    scopus 로고
    • Next-generation sequencing and novel variant determination in a cohort of 92 familial exudative vitreoretinopathy patients
    • Salvo, J., Lyubasyuk, V., Xu, M., Wang, H., Wang, F., Nguyen, D., et al. Next-generation sequencing and novel variant determination in a cohort of 92 familial exudative vitreoretinopathy patients. Investigative Ophthalmology & Visual Science 56:3 (2015), 1937–1946.
    • (2015) Investigative Ophthalmology & Visual Science , vol.56 , Issue.3 , pp. 1937-1946
    • Salvo, J.1    Lyubasyuk, V.2    Xu, M.3    Wang, H.4    Wang, F.5    Nguyen, D.6
  • 87
    • 70349745712 scopus 로고    scopus 로고
    • Expression of Wnt receptors in adult spiral ganglion neurons: Frizzled 9 localization at growth cones of regenerating neurites
    • Shah, S.M., Kang, Y.J., Christensen, B.L., Feng, A.S., Kollmar, R., Expression of Wnt receptors in adult spiral ganglion neurons: Frizzled 9 localization at growth cones of regenerating neurites. Neuroscience 164:2 (2009), 478–487.
    • (2009) Neuroscience , vol.164 , Issue.2 , pp. 478-487
    • Shah, S.M.1    Kang, Y.J.2    Christensen, B.L.3    Feng, A.S.4    Kollmar, R.5
  • 90
    • 56749104928 scopus 로고    scopus 로고
    • Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature
    • Stenman, J.M., Rajagopal, J., Carroll, T.J., Ishibashi, M., McMahon, J., McMahon, A.P., Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature. Science 322:5905 (2008), 1247–1250.
    • (2008) Science , vol.322 , Issue.5905 , pp. 1247-1250
    • Stenman, J.M.1    Rajagopal, J.2    Carroll, T.J.3    Ishibashi, M.4    McMahon, J.5    McMahon, A.P.6
  • 91
    • 0001511418 scopus 로고
    • Hereditary loop-tail in the house mouse accompanied by imperforate vagina and with lethal craniorachischisis when homozygous
    • Strong, L.C., Hollander, W.F., Hereditary loop-tail in the house mouse accompanied by imperforate vagina and with lethal craniorachischisis when homozygous. The Journal of Heredity 40 (1949), 329–334.
    • (1949) The Journal of Heredity , vol.40 , pp. 329-334
    • Strong, L.C.1    Hollander, W.F.2
  • 92
    • 0031688426 scopus 로고    scopus 로고
    • Van Gogh: A new Drosophila tissue polarity gene
    • Taylor, J., Abramova, N., Charlton, J., Adler, P.N., Van Gogh: A new Drosophila tissue polarity gene. Genetics 150:1 (1998), 199–210.
    • (1998) Genetics , vol.150 , Issue.1 , pp. 199-210
    • Taylor, J.1    Abramova, N.2    Charlton, J.3    Adler, P.N.4
  • 95
    • 84933043937 scopus 로고    scopus 로고
    • Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/beta-catenin pathway during brain angiogenesis
    • Vanhollebeke, B., Stone, O.A., Bostaille, N., Cho, C., Zhou, Y., Maquet, E., et al. Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/beta-catenin pathway during brain angiogenesis. eLife, 4, 2015, 10.7554/eLife.06489.
    • (2015) eLife , vol.4
    • Vanhollebeke, B.1    Stone, O.A.2    Bostaille, N.3    Cho, C.4    Zhou, Y.5    Maquet, E.6
  • 96
    • 0024972122 scopus 로고
    • A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains
    • Vinson, C.R., Conover, S., Adler, P.N., A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains. Nature 338:6212 (1989), 263–264.
    • (1989) Nature , vol.338 , Issue.6212 , pp. 263-264
    • Vinson, C.R.1    Conover, S.2    Adler, P.N.3
  • 98
    • 78649881432 scopus 로고    scopus 로고
    • When whorls collide: The development of hair patterns in frizzled 6 mutant mice
    • Wang, Y., Chang, H., Nathans, J., When whorls collide: The development of hair patterns in frizzled 6 mutant mice. Development 137:23 (2010), 4091–4099.
    • (2010) Development , vol.137 , Issue.23 , pp. 4091-4099
    • Wang, Y.1    Chang, H.2    Nathans, J.3
  • 99
    • 33645637038 scopus 로고    scopus 로고
    • The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells
    • Wang, Y., Guo, N., Nathans, J., The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. The Journal of Neuroscience 26:8 (2006), 2147–2156.
    • (2006) The Journal of Neuroscience , vol.26 , Issue.8 , pp. 2147-2156
    • Wang, Y.1    Guo, N.2    Nathans, J.3
  • 100
    • 0035399638 scopus 로고    scopus 로고
    • Progressive cerebellar, auditory, and esophageal dysfunction caused by targeted disruption of the frizzled-4 gene
    • Wang, Y., Huso, D., Cahill, H., Ryugo, D., Nathans, J., Progressive cerebellar, auditory, and esophageal dysfunction caused by targeted disruption of the frizzled-4 gene. The Journal of Neuroscience 21:13 (2001), 4761–4771.
    • (2001) The Journal of Neuroscience , vol.21 , Issue.13 , pp. 4761-4771
    • Wang, Y.1    Huso, D.2    Cahill, H.3    Ryugo, D.4    Nathans, J.5
  • 101
    • 0030068938 scopus 로고    scopus 로고
    • A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled
    • Wang, Y., Macke, J.P., Abella, B.S., Andreasson, K., Worley, P., Gilbert, D.J., et al. A large family of putative transmembrane receptors homologous to the product of the Drosophila tissue polarity gene frizzled. The Journal of Biological Chemistry 271:8 (1996), 4468–4476.
    • (1996) The Journal of Biological Chemistry , vol.271 , Issue.8 , pp. 4468-4476
    • Wang, Y.1    Macke, J.P.2    Abella, B.S.3    Andreasson, K.4    Worley, P.5    Gilbert, D.J.6
  • 102
    • 0038581580 scopus 로고    scopus 로고
    • Wnt signaling, Ca2 +, and cyclic GMP: Visualizing frizzled functions
    • Wang, H.Y., Malbon, C.C., Wnt signaling, Ca2 +, and cyclic GMP: Visualizing frizzled functions. Science 300:5625 (2003), 1529–1530.
    • (2003) Science , vol.300 , Issue.5625 , pp. 1529-1530
    • Wang, H.Y.1    Malbon, C.C.2
  • 103
    • 84870897220 scopus 로고    scopus 로고
    • Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity
    • Wang, Y., Rattner, A., Zhou, Y., Williams, J., Smallwood, P.M., Nathans, J., Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity. Cell 151:6 (2012), 1332–1344.
    • (2012) Cell , vol.151 , Issue.6 , pp. 1332-1344
    • Wang, Y.1    Rattner, A.2    Zhou, Y.3    Williams, J.4    Smallwood, P.M.5    Nathans, J.6
  • 104
    • 0031043863 scopus 로고    scopus 로고
    • A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23
    • Wang, Y.K., Samos, C.H., Peoples, R., Perez-Jurado, L.A., Nusse, R., Francke, U., A novel human homologue of the Drosophila frizzled wnt receptor gene binds wingless protein and is in the Williams syndrome deletion at 7q11.23. Human Molecular Genetics 6 (1997), 465–472.
    • (1997) Human Molecular Genetics , vol.6 , pp. 465-472
    • Wang, Y.K.1    Samos, C.H.2    Peoples, R.3    Perez-Jurado, L.A.4    Nusse, R.5    Francke, U.6
  • 105
    • 0036812502 scopus 로고    scopus 로고
    • Frizzled-3 is required for the development of major fiber tracts in the rostral CNS
    • Wang, Y., Thekdi, N., Smallwood, P.M., Macke, J.P., Nathans, J., Frizzled-3 is required for the development of major fiber tracts in the rostral CNS. The Journal of Neuroscience 22:19 (2002), 8563–8573.
    • (2002) The Journal of Neuroscience , vol.22 , Issue.19 , pp. 8563-8573
    • Wang, Y.1    Thekdi, N.2    Smallwood, P.M.3    Macke, J.P.4    Nathans, J.5
  • 106
    • 0001067788 scopus 로고
    • Local and general factors in the development of ‘pattern’ in Rhodnius prolixus
    • Wigglesworth, V.B., Local and general factors in the development of ‘pattern’ in Rhodnius prolixus. The Journal of Experimental Biology 17 (1940), 180–200.
    • (1940) The Journal of Experimental Biology , vol.17 , pp. 180-200
    • Wigglesworth, V.B.1
  • 107
    • 84875814154 scopus 로고    scopus 로고
    • Recessive mutations in the gene encoding frizzled 6 cause twenty nail dystrophy—Expanding the differential diagnosis for pachyonychia congenita
    • Wilson, N.J., Hansen, C.D., Azkur, D., Kocabas, C.N., Metin, A., Coskun, Z., et al. Recessive mutations in the gene encoding frizzled 6 cause twenty nail dystrophy—Expanding the differential diagnosis for pachyonychia congenita. Journal of Dermatological Science 70:1 (2013), 58–60.
    • (2013) Journal of Dermatological Science , vol.70 , Issue.1 , pp. 58-60
    • Wilson, N.J.1    Hansen, C.D.2    Azkur, D.3    Kocabas, C.N.4    Metin, A.5    Coskun, Z.6
  • 108
    • 0003801963 scopus 로고    scopus 로고
    • A new kind of science
    • Wolfram Media, Inc. Champagne, IL 1197 pp
    • Wolfram, S., A new kind of science. 2002, Wolfram Media, Inc., Champagne, IL 1197 pp.
    • (2002)
    • Wolfram, S.1
  • 109
    • 0027361185 scopus 로고
    • Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells
    • Wong, L.L., Adler, P.N., Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells. The Journal of Cell Biology 123:1 (1993), 209–221.
    • (1993) The Journal of Cell Biology , vol.123 , Issue.1 , pp. 209-221
    • Wong, L.L.1    Adler, P.N.2
  • 110
    • 12144289950 scopus 로고    scopus 로고
    • Vascular development in the retina and inner ear: Control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair
    • Xu, Q., Wang, Y., Dabdoub, A., Smallwood, P.M., Williams, J., Woods, C., et al. Vascular development in the retina and inner ear: Control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair. Cell 116:6 (2004), 883–895.
    • (2004) Cell , vol.116 , Issue.6 , pp. 883-895
    • Xu, Q.1    Wang, Y.2    Dabdoub, A.3    Smallwood, P.M.4    Williams, J.5    Woods, C.6
  • 111
    • 79951677187 scopus 로고    scopus 로고
    • Expression of the Norrie disease gene (Ndp) in developing and adult mouse eye, ear, and brain
    • Ye, X., Smallwood, P., Nathans, J., Expression of the Norrie disease gene (Ndp) in developing and adult mouse eye, ear, and brain. Gene Expression Patterns 11:1–2 (2011), 151–155.
    • (2011) Gene Expression Patterns , vol.11 , Issue.1-2 , pp. 151-155
    • Ye, X.1    Smallwood, P.2    Nathans, J.3
  • 112
    • 70349816655 scopus 로고    scopus 로고
    • Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization
    • Ye, X., Wang, Y., Cahill, H., Yu, M., Badea, T.C., Smallwood, P.M., et al. Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization. Cell 139:2 (2009), 285–298.
    • (2009) Cell , vol.139 , Issue.2 , pp. 285-298
    • Ye, X.1    Wang, Y.2    Cahill, H.3    Yu, M.4    Badea, T.C.5    Smallwood, P.M.6
  • 113
    • 79955140570 scopus 로고    scopus 로고
    • Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney
    • Ye, X., Wang, Y., Rattner, A., Nathans, J., Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney. Development 138:6 (2011), 1161–1172.
    • (2011) Development , vol.138 , Issue.6 , pp. 1161-1172
    • Ye, X.1    Wang, Y.2    Rattner, A.3    Nathans, J.4
  • 114
    • 78049338954 scopus 로고    scopus 로고
    • Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: General implications for tissue fusion processes
    • Yu, H., Smallwood, P.M., Wang, Y., Vidaltamayo, R., Reed, R., Nathans, J., Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: General implications for tissue fusion processes. Development 137:21 (2010), 3707–3717.
    • (2010) Development , vol.137 , Issue.21 , pp. 3707-3717
    • Yu, H.1    Smallwood, P.M.2    Wang, Y.3    Vidaltamayo, R.4    Reed, R.5    Nathans, J.6
  • 115
    • 84868552930 scopus 로고    scopus 로고
    • Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: Evidence for a network of interacting genes
    • Yu, H., Ye, X., Guo, N., Nathans, J., Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: Evidence for a network of interacting genes. Development 139:23 (2012), 4383–4394.
    • (2012) Development , vol.139 , Issue.23 , pp. 4383-4394
    • Yu, H.1    Ye, X.2    Guo, N.3    Nathans, J.4
  • 116
    • 58149237286 scopus 로고    scopus 로고
    • A nonautonomous role for retinal frizzled-5 in regulating hyaloid vitreous vasculature development
    • Zhang, J., Fuhrmann, S., Vetter, M.L., A nonautonomous role for retinal frizzled-5 in regulating hyaloid vitreous vasculature development. Investigative Ophthalmology & Visual Science 49:12 (2008), 5561–5567.
    • (2008) Investigative Ophthalmology & Visual Science , vol.49 , Issue.12 , pp. 5561-5567
    • Zhang, J.1    Fuhrmann, S.2    Vetter, M.L.3
  • 117
    • 21644448850 scopus 로고    scopus 로고
    • Hippocampal and visuospatial learning defects in mice with a deletion of frizzled 9, a gene in the Williams syndrome deletion interval
    • Zhao, C., Aviles, C., Abel, R.A., Almli, C.R., McQuillen, P., Pleasure, S.J., Hippocampal and visuospatial learning defects in mice with a deletion of frizzled 9, a gene in the Williams syndrome deletion interval. Development 132:12 (2005), 2917–2927.
    • (2005) Development , vol.132 , Issue.12 , pp. 2917-2927
    • Zhao, C.1    Aviles, C.2    Abel, R.A.3    Almli, C.R.4    McQuillen, P.5    Pleasure, S.J.6
  • 118
    • 33644959845 scopus 로고    scopus 로고
    • A transgenic marker mouse line labels Cajal-Retzius cells from the cortical hem and thalamocortical axons
    • Zhao, C., Guan, W., Pleasure, S.J., A transgenic marker mouse line labels Cajal-Retzius cells from the cortical hem and thalamocortical axons. Brain Research 1077:1 (2006), 48–53.
    • (2006) Brain Research , vol.1077 , Issue.1 , pp. 48-53
    • Zhao, C.1    Guan, W.2    Pleasure, S.J.3
  • 119
    • 44249105664 scopus 로고    scopus 로고
    • Early forebrain wiring: Genetic dissection using conditional Celsr3 mutant mice
    • Zhou, L., Bar, I., Achouri, Y., Campbell, K., De Backer, O., Hebert, J.M., et al. Early forebrain wiring: Genetic dissection using conditional Celsr3 mutant mice. Science 320:5878 (2008), 946–949.
    • (2008) Science , vol.320 , Issue.5878 , pp. 946-949
    • Zhou, L.1    Bar, I.2    Achouri, Y.3    Campbell, K.4    De Backer, O.5    Hebert, J.M.6
  • 120
    • 84908481545 scopus 로고    scopus 로고
    • Gpr124 controls CNS angiogenesis and blood–brain barrier integrity by promoting ligand-specific canonical Wnt signaling
    • Zhou, Y., Nathans, J., Gpr124 controls CNS angiogenesis and blood–brain barrier integrity by promoting ligand-specific canonical Wnt signaling. Developmental Cell 31:2 (2014), 248–256.
    • (2014) Developmental Cell , vol.31 , Issue.2 , pp. 248-256
    • Zhou, Y.1    Nathans, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.