Divergent clonal selection dominates medulloblastoma at recurrence

Nature

Volumn 529, Issue 7586, 2016, Pages 351-357

  Morrissy, A Sorana ^a   Garzia, Livia ^a   Shih, David J H ^a,b   Zuyderduyn, Scott ^b   Huang, Xi ^a   Skowron, Patryk ^a,b   Remke, Marc ^c   Cavalli, Florence M G ^a   Ramaswamy, Vijay ^a,b   Lindsay, Patricia E ^b,d   Jelveh, Salomeh ^d   Donovan, Laura K ^a   Wang, Xin ^a,b   Luu, Betty ^a   Zayne, Kory ^a   Li, Yisu ^e   Mayoh, Chelsea ^e   Thiessen, Nina ^e   Mercier, Eloi ^e   Mungall, Karen L ^e   Ma, Yusanne ^e   Tse, Kane ^e   Zeng, Thomas ^e   Shumansky, Karey ^e   Roth, Andrew J L ^e   Shah, Sohrab ^e   Farooq, Hamza ^a   Kijima, Noriyuki ^a   Holgado, Borja L ^a   Lee, John J Y ^a,b   Matan Lithwick, Stuart ^a   Liu, Jessica ^a   Mack, Stephen C ^a,f   Manno, Alex ^a   Michealraj, K A ^a   Nor, Carolina ^a   Peacock, John ^a,b   Qin, Lei ^a   Reimand, Juri ^a,b   Rolider, Adi ^a   Thompson, Yuan Y ^a,b   Wu, Xiaochong ^a   Pugh, Trevor ^d   Ally, Adrian ^e   Bilenky, Mikhail ^e   Butterfield, Yaron S N ^e   Carlsen, Rebecca ^e   Cheng, Young ^e   Chuah, Eric ^e   Corbett, Richard D ^e   Dhalla, Noreen ^e   He, An ^e   Lee, Darlene ^e   Li, Haiyan I ^e   Long, William ^e   Mayo, Michael ^e   Plettner, Patrick ^e   Qian, Jenny Q ^e   Schein, Jacqueline E ^e   Tam, Angela ^e   Wong, Tina ^e   Birol, Inanc ^e,g,h   Zhao, Yongjun ^e   Faria, Claudia C ⁱ   Pimentel, José ⁱ   Nunes, Sofia ^j   Shalaby, Tarek ^k   Grotzer, Michael ^k   Pollack, Ian F ^l   Hamilton, Ronald L ^l   Li, Xiao Nan ^m   Bendel, Anne E ⁿ   Fults, Daniel W ^o   Walter, Andrew W ^p   Kumabe, Toshihiro ^q   Tominaga, Teiji ^r   Collins, V Peter ^s   Cho, Yoon Jae ^t   Hoffman, Caitlin ^a   Lyden, David ^u   Wisoff, Jeffrey H ^v   Garvin, James H ^w   Stearns, Duncan S ^x   Massimi, Luca ^y   Schüller, Ulrich ^z   Sterba, Jaroslav ^aa   Zitterbart, Karel ^aa   Puget, Stephanie ^ab   Ayrault, Olivier ^ac   Dunn, Sandra E ^ad   Tirapelli, Daniela P C ^ae   Carlotti, Carlos G ^ae   Wheeler, Helen ^af   Hallahan, Andrew R ^ag   Ingram, Wendy ^ag,ah   MacDonald, Tobey J ^ai   Olson, Jeffrey J ^ai   Van Meir, Erwin G ^ai   Lee, Ji Yeoun ^aj   Wang, Kyu Chang ^aj   Kim, Seung Ki ^aj   Cho, Byung Kyu ^aj   Pietsch, Torsten ^ak   Fleischhack, Gudrun ^al   Tippelt, Stephan ^al   Ra, Young Shin ^am   Bailey, Simon ^an   Lindsey, Janet C ^an   Clifford, Steven C ^an   Eberhart, Charles G ^ao   Cooper, Michael K ^ap   Packer, Roger J ^aq   Massimino, Maura ^ar   Garre, Maria Luisa ^as   Bartels, Ute ^a   Tabori, Uri ^a   Hawkins, Cynthia E ^a   Dirks, Peter ^a   Bouffet, Eric ^a   Rutka, James T ^a,b   Wechsler Reya, Robert J ^at   Weiss, William A ^au   Collier, Lara S ^av   Dupuy, Adam J ^aw   Korshunov, Andrey ^ax   Jones, David T W ^ax   Kool, Marcel ^ax   Northcott, Paul A ^ax   Pfister, Stefan M ^ax,ay   Largaespada, David A ^az   Mungall, Andrew J ^e   Moore, Richard A ^e   Jabado, Nada ^ba   Bader, Gary D ^b,bb   Jones, Steven J M ^e,g,h   Malkin, David ^a,bc   Marra, Marco A ^e,g   Taylor, Michael D ^a,b   more..

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^d PRINCESS MARGARET HOSPITAL   (Canada)

^e BRITISH COLUMBIA CANCER AGENCY   (Canada)

^f LERNER RESEARCH INSTITUTE   (United States)

^g UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^h SIMON FRASER UNIVERSITY   (Canada)

ⁱ HOSPITAL DE SANTA MARIA   (Portugal)

^j INSTITUTO PORTUGUÊS DE ONCOLOGIA DE LISBOA FRANCISCO GENTIL   (Portugal)

^k UNIVERSITY CHILDREN S HOSPITAL   (Switzerland)

^l UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^m BAYLOR COLLEGE OF MEDICINE   (United States)

ⁿ CHILDREN S HOSPITALS AND CLINICS OF MINNESOTA   (United States)

^o UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^p NEMOURS ALFRED I DUPONT HOSPITAL FOR CHILDREN   (United States)

^q KITASATO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^r TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^s UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^t STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^u WEILL CORNELL MEDICAL COLLEGE   (United States)

^v NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^w Och Spine at New York Presbyterian Hospitals   (United States)

^x CASE WESTERN RESERVE UNIVERSITY   (United States)

^y CATHOLIC UNIVERSITY   (Italy)

^z UNIVERSITY OF MUNICH   (Germany)

^aa MASARYK UNIVERSITY   (Czech Republic)

^ab HÔPITAL NECKER ENFANTS MALADES   (France)

^ac INSTITUT CURIE   (France)

^ad BC CHILDREN S HOSPITAL   (Canada)

^ae UNIVERSITY OF SÃO PAULO   (Brazil)

^af UNIVERSITY OF SYDNEY   (Australia)

^ag LADY CILENTO CHILDREN S HOSPITAL   (Australia)

^ah UNIVERSITY OF QUEENSLAND   (Australia)

^ai EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^aj Seoul National University Children's Hospital   (South Korea)

^ak UNIVERSITY OF BONN   (Germany)

^al UNIVERSITY HOSPITAL ESSEN   (Germany)

^am University of Ulsan   (South Korea)

^an NEWCASTLE UNIVERSITY   (United Kingdom)

^ao JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^ap VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^aq CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^ar NATIONAL CANCER INSTITUTE   (Italy)

^as G GASLINI INSTITUTE   (Italy)

^at BURNHAM INSTITUTE   (United States)

^au UNIVERSITY OF CALIFORNIA   (United States)

^av UNIVERSITY OF WISCONSIN MADISON   (United States)

^aw UNIVERSITY OF IOWA   (United States)

^ax GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^ay UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^az UNIVERSITY OF MINNESOTA   (United States)

^ba MCGILL UNIVERSITY   (Canada)

^bb MOUNT SINAI HOSPITAL   (Canada)

^bc UNIVERSITY OF TORONTO   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE RECEPTOR; PROTEIN P53; SONIC HEDGEHOG PROTEIN;

CANCER; CLONE; DIVERGENCE; GENETIC ANALYSIS; GENOME; PROTEIN; RODENT; SELECTION; TUMOR;

ANIMAL MODEL; ARTICLE; CANCER RECURRENCE; CANCER RESISTANCE; CLINICAL TRIAL (TOPIC); CLONE; EXTRACELLULAR MATRIX; GENE MUTATION; GENE SEQUENCE; GENETIC VARIABILITY; GENOME; IN VIVO STUDY; MEDULLOBLASTOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; ANIMAL; CELL CLONE; CEREBELLAR NEOPLASMS; CRANIOSPINAL IRRADIATION; CYTOLOGY; DISEASE MODEL; DNA MUTATIONAL ANALYSIS; DROSOPHILA MELANOGASTER; DRUG EFFECTS; DRUG SCREENING; FEMALE; GENETIC SELECTION; GENETICS; HUMAN; HUMAN GENOME; IMAGE GUIDED RADIOTHERAPY; MALE; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY; PROCEDURES; TUMOR RECURRENCE;

MURINAE; MUS;

ANIMALS; CEREBELLAR NEOPLASMS; CLONE CELLS; CRANIOSPINAL IRRADIATION; DISEASE MODELS, ANIMAL; DNA MUTATIONAL ANALYSIS; DROSOPHILA MELANOGASTER; FEMALE; GENOME, HUMAN; HUMANS; MALE; MEDULLOBLASTOMA; MICE; MOLECULAR TARGETED THERAPY; NEOPLASM RECURRENCE, LOCAL; RADIOTHERAPY, IMAGE-GUIDED; SELECTION, GENETIC; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84955506668     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16478     Document Type: Article

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