DGIdb: Mining the druggable genome

Nature Methods

Volumn 10, Issue 12, 2013, Pages 1209-1210

  Griffith, Malachi ^a   Griffith, Obi L ^a   Coffman, Adam C ^a   Weible, James V ^a   Mcmichael, Josh F ^a   Spies, Nicholas C ^a   Koval, James ^a   Das, Indraniel ^a   Callaway, Matthew B ^a   Eldred, James M ^a   Miller, Christopher A ^a   Subramanian, Janakiraman ^a   Govindan, Ramaswamy ^a   Kumar, Runjun D ^a   Bose, Ron ^a,b   Ding, Li ^a   Walker, Jason R ^a   Larson, David E ^a   Dooling, David J ^a   Smith, Scott M ^a   Ley, Timothy J ^a,b   Mardis, Elaine R ^a,b   Wilson, Richard K ^a,b   more..

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPIDERMAL GROWTH FACTOR RECEPTOR 3; EPIDERMAL GROWTH FACTOR RECEPTOR 4; G PROTEIN COUPLED RECEPTOR; MAMMALIAN TARGET OF RAPAMYCIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR;

ARTICLE; BREAST CANCER; COMPUTER INTERFACE; DATA MINING; DRUG METABOLISM; EXOME; FOOD AND DRUG ADMINISTRATION; GENE AMPLIFICATION; GENE INTERACTION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC DATABASE; GENETIC VARIABILITY; GENOME ANALYSIS; GENOTYPE; HISTONE MODIFICATION; HUMAN; LUNG CANCER; PERSONALIZED MEDICINE; PHARMACOGENOMICS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN TARGETING;

ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; COMPUTATIONAL BIOLOGY; DATA MINING; DATABASES, GENETIC; DRUG DISCOVERY; DRUG INTERACTIONS; GENE EXPRESSION REGULATION; GENETIC VARIATION; GENOME; GENOMICS; HUMANS; LUNG NEOPLASMS; MUTATION; SOFTWARE; TECHNOLOGY, PHARMACEUTICAL;

EID: 84888862866     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.2689     Document Type: Article

References (37)

1. Hopkins, A.L. & Groom, C.R. Nat. Rev. Drug Discov. 1, 727-730 (2002).
2. Russ, A.P. & Lampel, S. Drug Discov. Today 10, 1607-1610 (2005).
3. Flicek, P. et al. Nucleic Acids Res. 39, D800-D806 (2011).
4. Maglott, D., Ostell, J., Pruitt, K.D. & Tatusova, T. Nucleic Acids Res. 39, D52-D57 (2011).
5. Wang, Y. et al. Nucleic Acids Res. 40, D400-D412 (2012).
6. Knox, C. et al. Nucleic Acids Res. 39, D1035-D1041 (2011).
7. McDonagh, E.M., Whirl-Carrillo, M., Garten, Y., Altman, R.B. & Klein, T.E. Biomarkers Med. 5, 795-806 (2011).
8. Somaiah, N. & Simon, G.R. J. Thorac. Oncol. 6, S1758-S1785 (2011).
9. Rask-Andersen, M., Almen, M.S. & Schioth, H.B. Nat. Rev. Drug Discov. 10, 579-590 (2011).
10. Zhu, F. et al. Nucleic Acids Res. 38, D787-D791 (2010).
11. Ashburner, M. et al. Nat. Genet. 25, 25-29 (2000).
12. Kumar, R.D., Chang, L.W., Ellis, M.J. & Bose, R. PLoS One 8, e67980 (2013).
13. Banerji, S. et al. Nature 486, 405-409 (2012).
14. Cancer Genome Atlas Network. Nature 490, 61-70 (2012).
15. Kan, Z. et al. Nature 466, 869-873 (2010).
16. Shah, S.P. et al. Nature 486, 395-399 (2012).
17. Stephens, P.J. et al. Nature 486, 400-404 (2012).
18. Bose, R. et al. Cancer Discov. 3, 224-237 (2013).
19. Yeh, P. et al. Clin. Cancer Res. 19, 1894-1901 (2013).
20. Hunter, S. et al. Nucleic Acids Res. 40, D306-D312 (2012).
21. Punta, M. et al. Nucleic Acids Res. 40, D290-D301 (2012).
22. Kuhn, M. et al. Nucleic Acids Res. 40, D876-D880 (2012).
23. Hecker, N. et al. Nucleic Acids Res. 40, D1113-D1117 (2012).
24. Gaulton, A. et al. Nucleic Acids Res. 40, D1100-D1107 (2012).
25. von Eichborn, J. et al. Nucleic Acids Res. 39, D1060-D1066 (2011).
26. Davis, A.P. et al. Nucleic Acids Res. 41, D1104-D1114 (2013).
27. Gao, Z. et al. BMC Bioinformatics 9, 104 (2008).
28. Manning, G., Whyte, D.B., Martinez, R., Hunter, T. & Sudarsanam, S. Science 298, 1912-1934 (2002).
29. Orth, A.P., Batalov, S., Perrone, M. & Chanda, S.K. Expert Opin. Ther. Targets 8, 587-596 (2004).
30. Lamb, J. et al. Science 313, 1929-1935 (2006).
31. Liu, T., Lin, Y., Wen, X., Jorissen, R.N. & Gilson, M.K. Nucleic Acids Res. 35, D198-D201 (2007).
32. Yang, W. et al. Nucleic Acids Res. 41, D955-D961 (2013).
33. Barretina, J. et al. Nature 483, 603-607 (2012).
34. Lim, E. et al. Nucleic Acids Res. 38, D781-D786 (2010).
35. Preissner, S. et al. Nucleic Acids Res. 38, D237-D243 (2010).
36. Kuhn, M., Campillos, M., Letunic, I., Jensen, L.J. & Bork, P. Mol. Syst. Biol. 6, 343 (2010).
37. Lounkine, E. et al. Nature 486, 361-367 (2012).