메뉴 건너뛰기




Volumn 32, Issue 9, 2014, Pages 886-896

Cytogenetic prognostication within medulloblastoma subgroups

(93)  Shih, David J H a,b   Northcott, Paul A f   Remke, Marc a,b   Korshunov, Andrey f   Ramaswamy, Vijay a,b   Kool, Marcel f   Luu, Betty a   Yao, Yuan a,b   Wang, Xin a,b   Dubuc, Adrian M a,b   Garzia, Livia a   Peacock, John a,b   Mack, Stephen C a,b   Wu, Xiaochong a   Rolider, Adi a   Morrissy, A Sorana a   Cavalli, Florence M G a   Jones, David T W f   Zitterbart, Karel j,k   Faria, Claudia C a,au   more..


Author keywords

[No Author keywords available]

Indexed keywords

MYC PROTEIN; TRANSCRIPTION FACTOR GLI2; TUMOR MARKER; GLI2 PROTEIN, HUMAN; KRUPPEL LIKE FACTOR; MYC PROTEIN, HUMAN; NUCLEAR PROTEIN; SHH PROTEIN, HUMAN; SONIC HEDGEHOG PROTEIN; WNT PROTEIN;

EID: 84899684426     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2013.50.9539     Document Type: Article
Times cited : (241)

References (64)
  • 2
    • 84862270168 scopus 로고    scopus 로고
    • The clinical implications of medulloblastoma subgroups
    • Northcott PA, Korshunov A, Pfister SM, et al: The clinical implications of medulloblastoma subgroups. Nat Rev Neurol 8:340-351, 2012
    • (2012) Nat Rev Neurol , vol.8 , pp. 340-351
    • Northcott, P.A.1    Korshunov, A.2    Pfister, S.M.3
  • 3
    • 84866532813 scopus 로고    scopus 로고
    • Hyperfractionated versus conventional radiotherapy followed by chemotherapy in standard-risk medulloblastoma: Results from the randomized multicenter HIT-SIOP PNET 4 trial
    • Lannering B, Rutkowski S, Doz F, et al: Hyperfractionated versus conventional radiotherapy followed by chemotherapy in standard-risk medulloblastoma: Results from the randomized multicenter HIT-SIOP PNET 4 trial. J Clin Oncol 30:3187-3193, 2012
    • (2012) J Clin Oncol , vol.30 , pp. 3187-3193
    • Lannering, B.1    Rutkowski, S.2    Doz, F.3
  • 4
    • 79959999815 scopus 로고    scopus 로고
    • Early aging in adult survivors of childhood medulloblastoma: Long-term neurocognitive, functional, and physical outcomes
    • Edelstein K, Spiegler BJ, Fung S, et al: Early aging in adult survivors of childhood medulloblastoma: Long-term neurocognitive, functional, and physical outcomes. Neuro Oncol 13:536-545, 2011
    • (2011) Neuro Oncol , vol.13 , pp. 536-545
    • Edelstein, K.1    Spiegler, B.J.2    Fung, S.3
  • 5
    • 78650087175 scopus 로고    scopus 로고
    • Neurocognitive outcome 12 months following cerebellar mutism syndrome in pediatric patients with medulloblastoma
    • Palmer SL, Hassall T, Evankovich K, et al: Neurocognitive outcome 12 months following cerebellar mutism syndrome in pediatric patients with medulloblastoma. Neuro Oncol 12:1311-1317, 2010
    • (2010) Neuro Oncol , vol.12 , pp. 1311-1317
    • Palmer, S.L.1    Hassall, T.2    Evankovich, K.3
  • 6
    • 72949098061 scopus 로고    scopus 로고
    • Impact of radiation avoidance on survival and neurocognitive outcome in infant medulloblastoma
    • Lafay-Cousin L, Bouffet E, Hawkins C, et al: Impact of radiation avoidance on survival and neurocognitive outcome in infant medulloblastoma. Curr Oncol 16:21-28, 2009
    • (2009) Curr Oncol , vol.16 , pp. 21-28
    • Lafay-Cousin, L.1    Bouffet, E.2    Hawkins, C.3
  • 7
    • 80053980912 scopus 로고    scopus 로고
    • FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma
    • Remke M, Hielscher T, Korshunov A, et al: FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma. J Clin Oncol 29:3852-3861, 2011
    • (2011) J Clin Oncol , vol.29 , pp. 3852-3861
    • Remke, M.1    Hielscher, T.2    Korshunov, A.3
  • 8
    • 79960119129 scopus 로고    scopus 로고
    • Adult medulloblastoma comprises three major molecular variants
    • Remke M, Hielscher T, Northcott PA, et al: Adult medulloblastoma comprises three major molecular variants. J Clin Oncol 29:2717-2723, 2011
    • (2011) J Clin Oncol , vol.29 , pp. 2717-2723
    • Remke, M.1    Hielscher, T.2    Northcott, P.A.3
  • 10
    • 84876959600 scopus 로고    scopus 로고
    • Methylation of the TERT promoter and risk stratification of childhood brain tumours: An integrative genomic and molecular study
    • Castelo-Branco P, Choufani S, Mack S, et al: Methylation of the TERT promoter and risk stratification of childhood brain tumours: An integrative genomic and molecular study. Lancet Oncol 14:534-542, 2013
    • (2013) Lancet Oncol , vol.14 , pp. 534-542
    • Castelo-Branco, P.1    Choufani, S.2    Mack, S.3
  • 11
    • 84870215426 scopus 로고    scopus 로고
    • Medulloblastomics: The end of the beginning
    • Northcott PA, Jones DT, Kool M, et al: Medulloblastomics: The end of the beginning. Nat Rev Cancer 12:818-834, 2012
    • (2012) Nat Rev Cancer , vol.12 , pp. 818-834
    • Northcott, P.A.1    Jones, D.T.2    Kool, M.3
  • 12
    • 78149411577 scopus 로고    scopus 로고
    • Molecular diagnostics of CNS embryonal tumors
    • Pfister SM, Korshunov A, Kool M, et al: Molecular diagnostics of CNS embryonal tumors. Acta Neuropathol 120:553-566, 2010
    • (2010) Acta Neuropathol , vol.120 , pp. 553-566
    • Pfister, S.M.1    Korshunov, A.2    Kool, M.3
  • 13
    • 84857091284 scopus 로고    scopus 로고
    • FISH and chips: The recipe for improved prognostication and outcomes for children with medulloblastoma
    • Ramaswamy V, Northcott PA, Taylor MD: FISH and chips: The recipe for improved prognostication and outcomes for children with medulloblastoma. Cancer Genet 204:577-588, 2011
    • (2011) Cancer Genet , vol.204 , pp. 577-588
    • Ramaswamy, V.1    Northcott, P.A.2    Taylor, M.D.3
  • 14
    • 76549086016 scopus 로고    scopus 로고
    • Genomics of medulloblastoma: From Giemsa-banding to next-generation sequencing in 20 years
    • Northcott PA, Rutka JT, Taylor MD: Genomics of medulloblastoma: From Giemsa-banding to next-generation sequencing in 20 years. Neurosurg Focus 28:E6, 2010
    • (2010) Neurosurg Focus , vol.28
    • Northcott, P.A.1    Rutka, J.T.2    Taylor, M.D.3
  • 17
    • 84862907577 scopus 로고    scopus 로고
    • Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations
    • Rausch T, Jones DT, Zapatka M, et al: Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations. Cell 148:59-71, 2012
    • (2012) Cell , vol.148 , pp. 59-71
    • Rausch, T.1    Jones, D.T.2    Zapatka, M.3
  • 18
    • 79951934386 scopus 로고    scopus 로고
    • TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma
    • Pfaff E, Remke M, Sturm D, et al: TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma. J Clin Oncol 28:5188-5196, 2010
    • (2010) J Clin Oncol , vol.28 , pp. 5188-5196
    • Pfaff, E.1    Remke, M.2    Sturm, D.3
  • 19
    • 77950497158 scopus 로고    scopus 로고
    • Universal poor survival in children with medulloblastoma harboring somatic TP53 mutations
    • Tabori U, Baskin B, Shago M, et al: Universal poor survival in children with medulloblastoma harboring somatic TP53 mutations. J Clin Oncol 28:1345-1350, 2010
    • (2010) J Clin Oncol , vol.28 , pp. 1345-1350
    • Tabori, U.1    Baskin, B.2    Shago, M.3
  • 21
    • 0030741967 scopus 로고    scopus 로고
    • Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma
    • Gilbertson RJ, Perry RH, Kelly PJ, et al: Prognostic significance of HER2 and HER4 coexpression in childhood medulloblastoma. Cancer Res 57:3272-3280, 1997 (Pubitemid 27351746)
    • (1997) Cancer Research , vol.57 , Issue.15 , pp. 3272-3280
    • Gilbertson, R.J.1    Perry, R.H.2    Kelly, P.J.3    Pearson, A.D.J.4    Lunec, J.5
  • 22
    • 0028918623 scopus 로고
    • Prognostic significance of the c-erbB-2 oncogene product in childhood medulloblastoma
    • Gilbertson RJ, Pearson AD, Perry RH, et al: Prognostic significance of the c-erbB-2 oncogene product in childhood medulloblastoma. Br J Cancer 71:473-477, 1995
    • (1995) Br J Cancer , vol.71 , pp. 473-477
    • Gilbertson, R.J.1    Pearson, A.D.2    Perry, R.H.3
  • 24
    • 0033843435 scopus 로고    scopus 로고
    • Neurotrophin receptor TrkC predicts good clinical outcome in medulloblastoma and other primitive neuroectodermal brain tumors
    • DOI 10.1055/s-2000-10044
    • Grotzer MA, Janss AJ, Phillips PC, et al: Neurotrophin receptor TrkC predicts good clinical outcome in medulloblastoma and other primitive neuroectodermal brain tumors. Klin Padiatr 212:196-199, 2000 (Pubitemid 30650554)
    • (2000) Klinische Padiatrie , vol.212 , Issue.4 , pp. 196-199
    • Grotzer, M.A.1    Janss, A.J.2    Phillips, P.C.3    Trojanowski, J.Q.4
  • 25
    • 0028568009 scopus 로고
    • Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma
    • Segal RA, Goumnerova LC, Kwon YK, et al: Expression of the neurotrophin receptor TrkC is linked to a favorable outcome in medulloblastoma. Proc Natl Acad Sci U S A 91:12867-12871, 1994
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 12867-12871
    • Segal, R.A.1    Goumnerova, L.C.2    Kwon, Y.K.3
  • 26
    • 79955770430 scopus 로고    scopus 로고
    • Chromosome 17 alterations identify good-risk and poor-risk tumors independently of clinical factors in medulloblastoma
    • McCabe MG, Bäcklund LM, Leong HS, et al: Chromosome 17 alterations identify good-risk and poor-risk tumors independently of clinical factors in medulloblastoma. Neuro Oncol 13:376-383, 2011
    • (2011) Neuro Oncol , vol.13 , pp. 376-383
    • McCabe, M.G.1    Bäcklund, L.M.2    Leong, H.S.3
  • 27
    • 37249090639 scopus 로고    scopus 로고
    • Gain of 1q is a potential univariate negative prognostic marker for survival in medulloblastoma
    • DOI 10.1158/1078-0432.CCR-07-1420
    • Lo KC, Ma C, Bundy BN, et al: Gain of 1q is a potential univariate negative prognostic marker for survival in medulloblastoma. Clin Cancer Res 13:7022-7028, 2007 (Pubitemid 350276883)
    • (2007) Clinical Cancer Research , vol.13 , Issue.23 , pp. 7022-7028
    • Lo, K.C.1    Ma, C.2    Bundy, B.N.3    Pomeroy, S.L.4    Eberhart, C.G.5    Cowell, J.K.6
  • 28
    • 84864425646 scopus 로고    scopus 로고
    • Subgroup-specific structural variation across 1,000 medulloblastoma genomes
    • Northcott PA, Shih DJ, Peacock J, et al: Subgroup-specific structural variation across 1,000 medulloblastoma genomes. Nature 488:49-56, 2012
    • (2012) Nature , vol.488 , pp. 49-56
    • Northcott, P.A.1    Shih, D.J.2    Peacock, J.3
  • 29
    • 63449115501 scopus 로고    scopus 로고
    • Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma
    • Northcott PA, Nakahara Y, Wu X, et al: Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma. Nat Genet 41:465-472, 2009
    • (2009) Nat Genet , vol.41 , pp. 465-472
    • Northcott, P.A.1    Nakahara, Y.2    Wu, X.3
  • 30
    • 79960842253 scopus 로고    scopus 로고
    • Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct
    • Northcott PA, Hielscher T, Dubuc A, et al: Pediatric and adult sonic hedgehog medulloblastomas are clinically and molecularly distinct. Acta Neuropathol 122:231-240, 2011
    • (2011) Acta Neuropathol , vol.122 , pp. 231-240
    • Northcott, P.A.1    Hielscher, T.2    Dubuc, A.3
  • 31
    • 63749118521 scopus 로고    scopus 로고
    • Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci
    • Pfister S, Remke M, Benner A, et al: Outcome prediction in pediatric medulloblastoma based on DNA copy-number aberrations of chromosomes 6q and 17q and the MYC and MYCN loci. J Clin Oncol 27:1627-1636, 2009
    • (2009) J Clin Oncol , vol.27 , pp. 1627-1636
    • Pfister, S.1    Remke, M.2    Benner, A.3
  • 32
    • 84863393028 scopus 로고    scopus 로고
    • Molecular subgroups of medulloblastoma: An international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, group 3, and group 4 medulloblastomas
    • Kool M, Korshunov A, Remke M, et al: Molecular subgroups of medulloblastoma: An international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, group 3, and group 4 medulloblastomas. Acta Neuropathol 123:473-484, 2012
    • (2012) Acta Neuropathol , vol.123 , pp. 473-484
    • Kool, M.1    Korshunov, A.2    Remke, M.3
  • 33
    • 62449244193 scopus 로고    scopus 로고
    • Chromosome 1q gain is not associated with a poor outcome in childhood medulloblastoma: Requirements for the validation of potential prognostic biomarkers
    • Clifford SC, O'Toole K, Ellison DW: Chromosome 1q gain is not associated with a poor outcome in childhood medulloblastoma: Requirements for the validation of potential prognostic biomarkers. Cell Cycle 8:787, 2009
    • (2009) Cell Cycle , vol.8 , pp. 787
    • Clifford, S.C.1    O'Toole, K.2    Ellison, D.W.3
  • 34
    • 85044706739 scopus 로고    scopus 로고
    • Wnt/wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis
    • Clifford SC, Lusher ME, Lindsey JC, et al: Wnt/wingless pathway activation and chromosome 6 loss characterize a distinct molecular sub-group of medulloblastomas associated with a favorable prognosis. Cell Cycle 5:2666-2670, 2006
    • (2006) Cell Cycle , vol.5 , pp. 2666-2670
    • Clifford, S.C.1    Lusher, M.E.2    Lindsey, J.C.3
  • 35
    • 77954602395 scopus 로고    scopus 로고
    • Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification
    • Korshunov A, Remke M, Werft W, et al: Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification. J Clin Oncol 28:3054-3060, 2010
    • (2010) J Clin Oncol , vol.28 , pp. 3054-3060
    • Korshunov, A.1    Remke, M.2    Werft, W.3
  • 36
    • 0029031125 scopus 로고
    • Prognostic implications of chromosome 17p deletions in human medulloblastomas
    • Batra SK, McLendon RE, Koo JS, et al: Prognostic implications of chromosome 17p deletions in human medulloblastomas. J Neurooncol 24:39-45, 1995
    • (1995) J Neurooncol , vol.24 , pp. 39-45
    • Batra, S.K.1    McLendon, R.E.2    Koo, J.S.3
  • 37
    • 84859559404 scopus 로고    scopus 로고
    • Prognostic classification of pediatric medulloblastoma based on chromosome 17p loss, expression of MYCC and MYCN, and Wnt pathway activation
    • Park AK, Lee SJ, Phi JH, et al: Prognostic classification of pediatric medulloblastoma based on chromosome 17p loss, expression of MYCC and MYCN, and Wnt pathway activation. Neuro Oncol 14:203-214, 2012
    • (2012) Neuro Oncol , vol.14 , pp. 203-214
    • Park, A.K.1    Lee, S.J.2    Phi, J.H.3
  • 38
    • 4143081483 scopus 로고    scopus 로고
    • Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients
    • DOI 10.1158/1078-0432.CCR-03-0721
    • Lamont JM, McManamy CS, Pearson AD, et al: Combined histopathological and molecular cytogenetic stratification of medulloblastoma patients. Clin Cancer Res 10:5482-5493, 2004 (Pubitemid 39100486)
    • (2004) Clinical Cancer Research , vol.10 , Issue.16 , pp. 5482-5493
    • Lamont, J.M.1    McManamy, C.S.2    Pearson, A.D.3    Clifford, S.C.4    Ellison, D.W.5
  • 43
    • 79954992066 scopus 로고    scopus 로고
    • Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables
    • Ellison DW, Kocak M, Dalton J, et al: Definition of disease-risk stratification groups in childhood medulloblastoma using combined clinical, pathologic, and molecular variables. J Clin Oncol 29:1400-1407, 2011
    • (2011) J Clin Oncol , vol.29 , pp. 1400-1407
    • Ellison, D.W.1    Kocak, M.2    Dalton, J.3
  • 44
    • 84862685324 scopus 로고    scopus 로고
    • MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma
    • Ryan SL, Schwalbe EC, Cole M, et al: MYC family amplification and clinical risk-factors interact to predict an extremely poor prognosis in childhood medulloblastoma. Acta Neuropathol 123:501-513, 2012
    • (2012) Acta Neuropathol , vol.123 , pp. 501-513
    • Ryan, S.L.1    Schwalbe, E.C.2    Cole, M.3
  • 46
    • 84862866448 scopus 로고    scopus 로고
    • Early recurrence in standard-risk medulloblastoma patients with the common idic(17)(p11.2) rearrangement
    • Bien-Willner GA, López-Terrada D, Bhattacharjee MB, et al: Early recurrence in standard-risk medulloblastoma patients with the common idic(17)(p11.2) rearrangement. Neuro Oncol 14:831-840, 2012
    • (2012) Neuro Oncol , vol.14 , pp. 831-840
    • Bien-Willner, G.A.1    López-Terrada, D.2    Bhattacharjee, M.B.3
  • 47
    • 75149149855 scopus 로고    scopus 로고
    • OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas
    • Adamson DC, Shi Q, Wortham M, et al: OTX2 is critical for the maintenance and progression of Shh-independent medulloblastomas. Cancer Res 70:181-191, 2010
    • (2010) Cancer Res , vol.70 , pp. 181-191
    • Adamson, D.C.1    Shi, Q.2    Wortham, M.3
  • 48
    • 84862278147 scopus 로고    scopus 로고
    • Biological and clinical heterogeneity of MYCN-amplified medulloblastoma
    • Korshunov A, Remke M, Kool M, et al: Biological and clinical heterogeneity of MYCN-amplified medulloblastoma. Acta Neuropathol 123:515-527, 2012
    • (2012) Acta Neuropathol , vol.123 , pp. 515-527
    • Korshunov, A.1    Remke, M.2    Kool, M.3
  • 49
    • 84878874877 scopus 로고    scopus 로고
    • DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies
    • Schwalbe EC, Williamson D, Lindsey JC, et al: DNA methylation profiling of medulloblastoma allows robust subclassification and improved outcome prediction using formalin-fixed biopsies. Acta Neuropathol 125:359-371, 2013
    • (2013) Acta Neuropathol , vol.125 , pp. 359-371
    • Schwalbe, E.C.1    Williamson, D.2    Lindsey, J.C.3
  • 51
    • 84862688169 scopus 로고    scopus 로고
    • Subgroup-specific alternative splicing in medulloblastoma
    • Dubuc AM, Morrissy AS, Kloosterhof NK, et al: Subgroup-specific alternative splicing in medulloblastoma. Acta Neuropathol 123:485-499, 2012
    • (2012) Acta Neuropathol , vol.123 , pp. 485-499
    • Dubuc, A.M.1    Morrissy, A.S.2    Kloosterhof, N.K.3
  • 52
    • 84860821444 scopus 로고    scopus 로고
    • Molecular subgroups of medulloblastoma: The current consensus
    • Taylor MD, Northcott PA, Korshunov A, et al: Molecular subgroups of medulloblastoma: The current consensus. Acta Neuropathol 123:465-472, 2012
    • (2012) Acta Neuropathol , vol.123 , pp. 465-472
    • Taylor, M.D.1    Northcott, P.A.2    Korshunov, A.3
  • 53
    • 79955034739 scopus 로고    scopus 로고
    • Medulloblastoma comprises four distinct molecular variants
    • Northcott PA, Korshunov A, Witt H, et al: Medulloblastoma comprises four distinct molecular variants. J Clin Oncol 29:1408-1414, 2011
    • (2011) J Clin Oncol , vol.29 , pp. 1408-1414
    • Northcott, P.A.1    Korshunov, A.2    Witt, H.3
  • 54
    • 84864419974 scopus 로고    scopus 로고
    • Dissecting the genomic complexity underlying medulloblastoma
    • Jones DT, Jäger N, Kool M, et al: Dissecting the genomic complexity underlying medulloblastoma. Nature 488:100-105, 2012
    • (2012) Nature , vol.488 , pp. 100-105
    • Jones, D.T.1    Jäger, N.2    Kool, M.3
  • 55
    • 52449119078 scopus 로고    scopus 로고
    • Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
    • Kool M, Koster J, Bunt J, et al: Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One 3:e3088, 2008
    • (2008) PLoS One , vol.3
    • Kool, M.1    Koster, J.2    Bunt, J.3
  • 56
    • 79251629946 scopus 로고    scopus 로고
    • The genetic landscape of the childhood cancer medulloblastoma
    • Parsons DW, Li M, Zhang X, et al: The genetic landscape of the childhood cancer medulloblastoma. Science 331:435-439, 2011
    • (2011) Science , vol.331 , pp. 435-439
    • Parsons, D.W.1    Li, M.2    Zhang, X.3
  • 57
    • 84864444165 scopus 로고    scopus 로고
    • Novel mutations target distinct subgroups of medulloblastoma
    • Robinson G, Parker M, Kranenburg TA, et al: Novel mutations target distinct subgroups of medulloblastoma. Nature 488:43-48, 2012
    • (2012) Nature , vol.488 , pp. 43-48
    • Robinson, G.1    Parker, M.2    Kranenburg, T.A.3
  • 58
    • 79953321410 scopus 로고    scopus 로고
    • Rapid diagnosis of medulloblastoma molecular subgroups
    • Schwalbe EC, Lindsey JC, Straughton D, et al: Rapid diagnosis of medulloblastoma molecular subgroups. Clin Cancer Res 17:1883-1894, 2011
    • (2011) Clin Cancer Res , vol.17 , pp. 1883-1894
    • Schwalbe, E.C.1    Lindsey, J.C.2    Straughton, D.3
  • 59
    • 79954444747 scopus 로고    scopus 로고
    • Medulloblastoma: Clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups
    • Ellison DW, Dalton J, Kocak M, et al: Medulloblastoma: Clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups. Acta Neuropathol 121:381-396, 2011
    • (2011) Acta Neuropathol , vol.121 , pp. 381-396
    • Ellison, D.W.1    Dalton, J.2    Kocak, M.3
  • 60
    • 78650811198 scopus 로고    scopus 로고
    • Subtypes of medulloblastoma have distinct developmental origins
    • Gibson P, Tong Y, Robinson G, et al: Subtypes of medulloblastoma have distinct developmental origins. Nature 468:1095-1099, 2010
    • (2010) Nature , vol.468 , pp. 1095-1099
    • Gibson, P.1    Tong, Y.2    Robinson, G.3
  • 61
    • 84862680481 scopus 로고    scopus 로고
    • Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples
    • Northcott PA, Shih DJ, Remke M, et al: Rapid, reliable, and reproducible molecular sub-grouping of clinical medulloblastoma samples. Acta Neuropathol 123:615-626, 2012
    • (2012) Acta Neuropathol , vol.123 , pp. 615-626
    • Northcott, P.A.1    Shih, D.J.2    Remke, M.3
  • 62
    • 84864492215 scopus 로고    scopus 로고
    • Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations
    • Pugh TJ, Weeraratne SD, Archer TC, et al: Medulloblastoma exome sequencing uncovers subtype-specific somatic mutations. Nature 488:106-110, 2012
    • (2012) Nature , vol.488 , pp. 106-110
    • Pugh, T.J.1    Weeraratne, S.D.2    Archer, T.C.3
  • 63
    • 79954991010 scopus 로고    scopus 로고
    • Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome
    • Cho YJ, Tsherniak A, Tamayo P, et al: Integrative genomic analysis of medulloblastoma identifies a molecular subgroup that drives poor clinical outcome. J Clin Oncol 29:1424-1430, 2011
    • (2011) J Clin Oncol , vol.29 , pp. 1424-1430
    • Cho, Y.J.1    Tsherniak, A.2    Tamayo, P.3
  • 64
    • 84878963850 scopus 로고    scopus 로고
    • MYC and MYCN amplification can be reliably assessed by aCGH in medulloblastoma
    • Bourdeaut F, Grison C, Maurage CA, et al: MYC and MYCN amplification can be reliably assessed by aCGH in medulloblastoma. Cancer Genet 206:124-129, 2013
    • (2013) Cancer Genet , vol.206 , pp. 124-129
    • Bourdeaut, F.1    Grison, C.2    Maurage, C.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.