Soybean extracts increase cell surface ZIP4 abundance and cellular zinc levels: A potential novel strategy to enhance zinc absorption by ZIP4 targeting

Biochemical Journal

Volumn 472, Issue 2, 2015, Pages 183-193

  Hashimoto, Ayako ^a   Ohkura, Katsuma ^b   Takahashi, Masakazu ^b   Kizu, Kumiko ^c   Narita, Hiroshi ^d   Enomoto, Shuichi ^e,f   Miyamae, Yusaku ^a   Masuda, Seiji ^a   Nagao, Masaya ^a   Irie, Kazuhiro ^a   Ohigashi, Hajime ^b   Andrews, Glen K ^g   Kambe, Taiho ^a  

^a KYOTO UNIVERSITY   (Japan)

^b FUKUI PREFECTURAL UNIVERSITY   (Japan)

^c Osaka Seikei College   (Japan)

^d KYOTO WOMEN'S UNIVERSITY   (Japan)

^e OKAYAMA UNIVERSITY   (Japan)

^f RIKEN KOBE INSTITUTE   (Japan)

^g UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

Apical membrane; Degradation; Endocytosis; Screening; Soyasaponin Bb; Zinc transporter

Indexed keywords

BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; CELL SURFACE PROTEIN; DOXYCYCLINE; METALLOTHIONEIN I; PROTEIN ZIP4; SAPONIN; SHG SOYBEAN EXTRACT; SOYASAPONIN BB; SOYBEAN EXTRACT; SSA SOYBEAN EXTRACT; UNCLASSIFIED DRUG; ZINC; ZINC TRANSPORTER; CATION TRANSPORT PROTEIN; GASTROINTESTINAL AGENT; HYBRID PROTEIN; PLANT EXTRACT; SLC39A4 PROTEIN, MOUSE;

ABSORPTION; ANIMAL CELL; APICAL MEMBRANE; ARTICLE; CELL SURFACE; CONTROLLED STUDY; ENDOCYTOSIS; FEMALE; HUMAN; HUMAN CELL; INTESTINE EPITHELIUM CELL; MOUSE; MUTATION ACCUMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TRANSPORT AT THE CELLULAR LEVEL; AGONISTS; ANIMAL; CACO 2 CELL LINE; CELL LINE; CELL MEMBRANE; CHEMISTRY; COMPARATIVE STUDY; CYTOLOGY; DEFICIENCY; DEFICIENCY DISEASES; DIET SUPPLEMENTATION; DOG; GENE EXPRESSION REGULATION; GENETICS; INTESTINE ABSORPTION; INTESTINE CELL; METABOLISM; PLANT SEED; PROTEIN STABILITY; SOYBEAN;

ANIMALS; CACO-2 CELLS; CATION TRANSPORT PROTEINS; CELL LINE; CELL MEMBRANE; DEFICIENCY DISEASES; DIETARY SUPPLEMENTS; DOGS; ENDOCYTOSIS; ENTEROCYTES; GASTROINTESTINAL AGENTS; GENE EXPRESSION REGULATION; HUMANS; INTESTINAL ABSORPTION; MICE; PLANT EXTRACTS; PROTEIN STABILITY; RECOMBINANT FUSION PROTEINS; SAPONINS; SEEDS; SOYBEANS; ZINC;

EID: 84955478516     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20150862     Document Type: Article

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