O-linked glycosylation at threonine 27 protects the copper transporter hCTR1 from proteolytic cleavage in mammalian cells

Journal of Biological Chemistry

Volumn 282, Issue 28, 2007, Pages 20376-20387

  Maryon, Edward B ^a   Molloy, Shannon A ^a   Kaplan, Jack H ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALIAN CELLS; PROTEOLYTIC CLEAVAGE; TRANSPORT ACTIVITY;

AMINO ACIDS; CELL MEMBRANES; COPPER; POLYPEPTIDES; PROTEINS; SUGARS;

GLYCOSYLATION;

ALANINE; COPPER PROTEIN; GLYCOSIDASE; HUMAN COPPER TRANSPORTER 1; MUTANT PROTEIN; POLYPEPTIDE; POLYSACCHARIDE; SUGAR; THREONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE; CELL MIGRATION; CELL STRAIN HEK293; CELLULAR DISTRIBUTION; CHO CELL; CONTROLLED STUDY; COPPER METABOLISM; EMBRYO; FEMALE; GLYCOSYLATION; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; WILD TYPE;

AMINO ACID SUBSTITUTION; ANIMALS; CACO-2 CELLS; CATION TRANSPORT PROTEINS; CHO CELLS; COPPER; CRICETINAE; CRICETULUS; DOGS; GENE EXPRESSION; GLYCOSYLATION; HUMANS; ION TRANSPORT; MUTATION, MISSENSE; PROTEIN MODIFICATION, TRANSLATIONAL; PROTEIN STRUCTURE, TERTIARY; THREONINE;

CRICETULUS GRISEUS; MAMMALIA;

EID: 34547131326     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M701806200     Document Type: Article

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