-
1
-
-
37149034911
-
Strategies to advance translational research into brain barriers
-
Neuwelt, E. et al. Strategies to advance translational research into brain barriers. Lancet Neurol. 7, 84-96 (2008).
-
(2008)
Lancet Neurol.
, vol.7
, pp. 84-96
-
-
Neuwelt, E.1
-
2
-
-
22944483792
-
The blood-brain barrier/neurovascular unit in health and disease
-
Hawkins, B. T. & Davis, T. P. The blood-brain barrier/neurovascular unit in health and disease. Pharmacol. Rev. 57, 173-185 (2005).
-
(2005)
Pharmacol. Rev.
, vol.57
, pp. 173-185
-
-
Hawkins, B.T.1
Davis, T.P.2
-
3
-
-
78649487239
-
Pericytes are required for blood-brain barrier integrity during embryogenesis
-
Daneman, R., Zhou, L., Kebede, A. A. & Barres, B. A. Pericytes are required for blood-brain barrier integrity during embryogenesis. Nature 468, 562-566 (2010).
-
(2010)
Nature
, vol.468
, pp. 562-566
-
-
Daneman, R.1
Zhou, L.2
Kebede, A.A.3
Barres, B.A.4
-
4
-
-
29244463365
-
Astrocyte-endothelial interactions at the blood-brain barrier
-
Abbott, N. J., Ronnback, L. & Hansson, E. Astrocyte-endothelial interactions at the blood-brain barrier. Nat. Rev. Neurosci. 7, 41-53 (2006).
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 41-53
-
-
Abbott, N.J.1
Ronnback, L.2
Hansson, E.3
-
5
-
-
84918504547
-
The blood-brain barrier in neuroimmunology: Tales of separation and assimilation
-
Banks, W. A. The blood-brain barrier in neuroimmunology: Tales of separation and assimilation. Brain Behav. Immun. 44, 1-8 (2015).
-
(2015)
Brain Behav. Immun.
, vol.44
, pp. 1-8
-
-
Banks, W.A.1
-
6
-
-
84861418194
-
Apolipoprotein e controls cerebrovascular integrity via cyclophilin A
-
Bell, R. D. et al. Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. Nature 485, 512-516 (2012).
-
(2012)
Nature
, vol.485
, pp. 512-516
-
-
Bell, R.D.1
-
7
-
-
0015186836
-
Brain uptake of radio-labelled amino acids, amines and hexoses after arterial injection
-
Oldendorf, W. H. Brain uptake of radio-labelled amino acids, amines and hexoses after arterial injection. Am. J. Physiol. 221, 1629-1639 (1971).
-
(1971)
Am. J. Physiol.
, vol.221
, pp. 1629-1639
-
-
Oldendorf, W.H.1
-
8
-
-
48949117592
-
Blood-brain barrier and feeding: Regulatory roles of saturable transport systems for ingestive peptides
-
Kastin, A. J. & Pan, W. Blood-brain barrier and feeding: Regulatory roles of saturable transport systems for ingestive peptides. Curr. Pharm. Design 14, 1615-1619 (2008).
-
(2008)
Curr. Pharm. Design
, vol.14
, pp. 1615-1619
-
-
Kastin, A.J.1
Pan, W.2
-
9
-
-
0037237881
-
Interactions of cytokines with blood-brain barrier: Implications for feeding
-
Pan, W. & Kastin, A. J. Interactions of cytokines with blood-brain barrier: Implications for feeding. Curr. Pharm. Design 9, 827-831 (2003).
-
(2003)
Curr. Pharm. Design
, vol.9
, pp. 827-831
-
-
Pan, W.1
Kastin, A.J.2
-
10
-
-
0035015218
-
Delivery across the blood-brain barrier of antisense directed againt amyloid β reversal of learning and memory deficits in mice overexpressing amyloid precursor protein
-
Banks, W. A. et al. Delivery across the blood-brain barrier of antisense directed againt amyloid β: Reversal of learning and memory deficits in mice overexpressing amyloid precursor protein. J. Pharmacol. Exp. Ther. 297, 1113-1121 (2001).
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.297
, pp. 1113-1121
-
-
Banks, W.A.1
-
11
-
-
0034653109
-
Treatment of experimental autoimmune encephalomyelitis with antisense oligonucleotides against the low affinity neurotrophin receptor
-
Soilu-Hanninen, M. et al. Treatment of experimental autoimmune encephalomyelitis with antisense oligonucleotides against the low affinity neurotrophin receptor. J. Neurosci. Res. 59, 712-721 (2000).
-
(2000)
J. Neurosci. Res.
, vol.59
, pp. 712-721
-
-
Soilu-Hanninen, M.1
-
12
-
-
84858020530
-
Peripheral administration of antisense oligonucleotides targeting the amyloid-β protein precursor reverses AβPP and LRP-1 overexpression in aged SAMP8 mouse brain
-
Erickson, M. A. et al. Peripheral administration of antisense oligonucleotides targeting the amyloid-β protein precursor reverses AβPP and LRP-1 overexpression in aged SAMP8 mouse brain. J. Alzheimers Dis. 28, 951-960 (2012).
-
(2012)
J. Alzheimers Dis.
, vol.28
, pp. 951-960
-
-
Erickson, M.A.1
-
13
-
-
84891589937
-
Antisense oligonucelotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer's disease
-
Farr, S. A. et al. Antisense oligonucelotide against GSK-3β in brain of SAMP8 mice improves learning and memory and decreases oxidative stress: Involvement of transcription factor Nrf2 and implications for Alzheimer's disease. Free Radic. Biol. Med. 67, 387-395 (2013).
-
(2013)
Free Radic. Biol. Med.
, vol.67
, pp. 387-395
-
-
Farr, S.A.1
-
14
-
-
59149103611
-
Isolation of peptide transport system-6 from brain endothelial cells: Therapeutic effects with antisense inhibition in Alzheimer's and stroke models
-
Dogrukol-Ak, D. et al. Isolation of peptide transport system-6 from brain endothelial cells: Therapeutic effects with antisense inhibition in Alzheimer's and stroke models. J. Cereb. Blood Flow Metab. 29, 411-422 (2009).
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, pp. 411-422
-
-
Dogrukol-Ak, D.1
-
15
-
-
22744455017
-
Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the A? Region of amyloid precursor protein
-
Poon, H. F. et al. Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the A? region of amyloid precursor protein. Brain Res. Mol. Brain Res. 138, 8-13 (2005).
-
(2005)
Brain Res. Mol. Brain Res.
, vol.138
, pp. 8-13
-
-
Poon, H.F.1
-
16
-
-
84901798645
-
Central and peripheral administration of antisense oligonucleotide targeting amyloid precursor protein improves learning and memory and reduces neuroinflammatory cytokines in Tg2576 (APPswe) mice
-
Farr, S. A., Erickson, M. A., Niehoff, M. L., Banks, W. A. & Morley, J. E. Central and peripheral administration of antisense oligonucleotide targeting amyloid precursor protein improves learning and memory and reduces neuroinflammatory cytokines in Tg2576 (APPswe) mice. J. Alzheimers Dis. 40, 1005-1016 (2014).
-
(2014)
J. Alzheimers Dis.
, vol.40
, pp. 1005-1016
-
-
Farr, S.A.1
Erickson, M.A.2
Niehoff, M.L.3
Banks, W.A.4
Morley, J.E.5
-
17
-
-
0029928170
-
Permeability at the blood-brain barrier and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF
-
Poduslo, J. F. & Curran, G. L. Permeability at the blood-brain barrier and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF. Mol. Brain Res. 36, 280-286 (1996).
-
(1996)
Mol. Brain Res.
, vol.36
, pp. 280-286
-
-
Poduslo, J.F.1
Curran, G.L.2
-
18
-
-
0032404127
-
Transport of brain-derived neurotrophic factor across the blood-brain barrier
-
Pan, W., Banks, W. A., Fasold, M. B., Bluth, J. & Kastin, A. J. Transport of brain-derived neurotrophic factor across the blood-brain barrier. Neuropharmacology 37, 1553-1561 (1998).
-
(1998)
Neuropharmacology
, vol.37
, pp. 1553-1561
-
-
Pan, W.1
Banks, W.A.2
Fasold, M.B.3
Bluth, J.4
Kastin, A.J.5
-
19
-
-
20344386484
-
Branched-chain amino acids and brain function
-
Fernstrom, J. D. Branched-chain amino acids and brain function. J. Nutr. 135, 1439S-1546S (2005).
-
(2005)
J. Nutr.
, vol.135
, pp. 1439-1546
-
-
Fernstrom, J.D.1
-
20
-
-
67649665611
-
Pegylated leptin antagonist is a potent orexigenic agent: Preparation and mechanism of activity
-
Elinav, E. et al. Pegylated leptin antagonist is a potent orexigenic agent: Preparation and mechanism of activity. Endocrinology 150, 3083-3091 (2009).
-
(2009)
Endocrinology
, vol.150
, pp. 3083-3091
-
-
Elinav, E.1
-
21
-
-
84919793659
-
Smuggling drugs into the brain: An overview of ligands targeting transcytosis for drug delivery across the blood-brain barrier
-
Georgieva, J. V., Hoekstra, D. & Zuhorn, I. S. Smuggling drugs into the brain: An overview of ligands targeting transcytosis for drug delivery across the blood-brain barrier. Pharmaceutics 6, 557-583 (2014).
-
(2014)
Pharmaceutics
, vol.6
, pp. 557-583
-
-
Georgieva, J.V.1
Hoekstra, D.2
Zuhorn, I.S.3
-
22
-
-
84962259534
-
Blood-brain barrier drug delivery of IgG fusion proteins with a transferrin receptor monoclonal antibody
-
Pardridge, W. M. Blood-brain barrier drug delivery of IgG fusion proteins with a transferrin receptor monoclonal antibody. Expert Opin. Drug Deliv. 20, 1-16 (2014).
-
(2014)
Expert Opin. Drug Deliv.
, vol.20
, pp. 1-16
-
-
Pardridge, W.M.1
-
23
-
-
11144273976
-
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
-
Wang, T. et al. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat. Med. 10, 1366-1373 (2004).
-
(2004)
Nat. Med.
, vol.10
, pp. 1366-1373
-
-
Wang, T.1
-
24
-
-
84862639014
-
Human immunodeficiency virus-1 uses the mannose-6-phosphate receptor to cross the blood-brain barrier
-
Dohgu, S., Ryerse, J. S., Robinson, S. M. & Banks, W. A. Human immunodeficiency virus-1 uses the mannose-6-phosphate receptor to cross the blood-brain barrier. PLoS ONE 7, e41623 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e41623
-
-
Dohgu, S.1
Ryerse, J.S.2
Robinson, S.M.3
Banks, W.A.4
-
26
-
-
84962209087
-
Pathogen-inspired drug delivery to the central nervous system
-
McCall, R. L. et al. Pathogen-inspired drug delivery to the central nervous system. Tissue Barriers 8, 3944449 (2014).
-
(2014)
Tissue Barriers
, vol.8
, pp. 3944449
-
-
McCall, R.L.1
-
27
-
-
79957452852
-
A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo
-
Atwal, J. K. et al. A therapeutic antibody targeting BACE1 inhibits amyloid-β production in vivo. Sci. Transl Med. 3, 84ra43 (2011).
-
(2011)
Sci. Transl Med.
, vol.3
, pp. 84-143
-
-
Atwal, J.K.1
-
28
-
-
79957439772
-
Boosting brain uptake of the therapeutic antibody by reducing its affinity for a transcytosis target
-
Yu, Y. J. et al. Boosting brain uptake of the therapeutic antibody by reducing its affinity for a transcytosis target. Sci. Transl Med. 3, 84ra44 (2011).
-
(2011)
Sci. Transl Med.
, vol.3
, pp. 84-144
-
-
Yu, Y.J.1
-
29
-
-
84891804917
-
Increased brain penetration and potency of a therapeutic antibody using a monovalent molecular shuttle
-
Niewoehner, J. et al. Increased brain penetration and potency of a therapeutic antibody using a monovalent molecular shuttle. Neuron 81, 49-60 (2014).
-
(2014)
Neuron
, vol.81
, pp. 49-60
-
-
Niewoehner, J.1
-
30
-
-
0034467123
-
Regional variations in the transport of interleukin-1? Across the blood-brain barrier in ICR and aging SAMP8 mice
-
Moinuddin, A., Morley, J. E. & Banks, W. A. Regional variations in the transport of interleukin-1? across the blood-brain barrier in ICR and aging SAMP8 mice. Neuroimmunomodulation 8, 165-170 (2000).
-
(2000)
Neuroimmunomodulation
, vol.8
, pp. 165-170
-
-
Moinuddin, A.1
Morley, J.E.2
Banks, W.A.3
-
31
-
-
0028973573
-
Selective transport of blood-borne interleukin-1? into the posterior division of the septum of the mouse brain
-
Maness, L. M., Banks, W. A., Zadina, J. E. & Kastin, A. J. Selective transport of blood-borne interleukin-1? into the posterior division of the septum of the mouse brain. Brain Res. 700, 83-88 (1995).
-
(1995)
Brain Res.
, vol.700
, pp. 83-88
-
-
Maness, L.M.1
Banks, W.A.2
Zadina, J.E.3
Kastin, A.J.4
-
32
-
-
1642454475
-
ABC transporters and the blood-brain barrier
-
Begley, D. J. ABC transporters and the blood-brain barrier. Curr. Pharm. Design 10, 1295-1312 (2004).
-
(2004)
Curr. Pharm. Design
, vol.10
, pp. 1295-1312
-
-
Begley, D.J.1
-
33
-
-
84891160650
-
Efficacy of verapamil as an adjunctive treatment in children with drug-resistant epilepsy: A pilot study
-
Nicita, F. et al. Efficacy of verapamil as an adjunctive treatment in children with drug-resistant epilepsy: A pilot study. Seizure 23, 36-40 (2014).
-
(2014)
Seizure
, vol.23
, pp. 36-40
-
-
Nicita, F.1
-
34
-
-
0031893415
-
Regulation of the cerebral circulation: Role of endothelium and potassium channels
-
Faraci, F. M. & Heistad, D. D. Regulation of the cerebral circulation: Role of endothelium and potassium channels. Physiol. Rev. 78, 53-97 (1998).
-
(1998)
Physiol. Rev.
, vol.78
, pp. 53-97
-
-
Faraci, F.M.1
Heistad, D.D.2
-
35
-
-
0033397024
-
Brain endothelial cell production of a neuroprotective cytokine, interleukin-6, in response to noxious stimuli
-
Reyes, T. M., Fabry, Z. & Coe, C. L. Brain endothelial cell production of a neuroprotective cytokine, interleukin-6, in response to noxious stimuli. Brain Res. 851, 215-220 (1999).
-
(1999)
Brain Res.
, vol.851
, pp. 215-220
-
-
Reyes, T.M.1
Fabry, Z.2
Coe, C.L.3
-
36
-
-
0036209872
-
Cerebral endothelial cells are a major source of adrenomedullin
-
Kis, B. et al. Cerebral endothelial cells are a major source of adrenomedullin. J. Neuroendocrinol. 14, 283-293 (2002).
-
(2002)
J. Neuroendocrinol.
, vol.14
, pp. 283-293
-
-
Kis, B.1
-
37
-
-
82255169278
-
Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF
-
Dohgu, S., Fleegal-DeMotta, M. A. & Banks, W. A. Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF. J. Neuroinflamm. 8, 167 (2011).
-
(2011)
J. Neuroinflamm.
, vol.8
, pp. 167
-
-
Dohgu, S.1
Fleegal-DeMotta, M.A.2
Banks, W.A.3
-
38
-
-
0030787985
-
Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain
-
Cao, C., Matsumura, K., Yamagata, K. & Watanabe, Y. Involvement of cyclooxygenase-2 in LPS-induced fever and regulation of its mRNA by LPS in the rat brain. Am. J. Physiol. 272, R1712-R1725 (1997).
-
(1997)
Am. J. Physiol.
, vol.272
, pp. 1712-1725
-
-
Cao, C.1
Matsumura, K.2
Yamagata, K.3
Watanabe, Y.4
-
39
-
-
84879488912
-
Brain pericytes increase the lipopolysaccharide-enhanced transcytosis of HIV-1 free virus across the in vitro blood-brain barrier: Evidence for cytokine-mediated pericyte-endothelial cell cross talk
-
Dohgu, S. & Banks, W. A. Brain pericytes increase the lipopolysaccharide-enhanced transcytosis of HIV-1 free virus across the in vitro blood-brain barrier: Evidence for cytokine-mediated pericyte-endothelial cell cross talk. Fluids Barriers CNS 10, 23 (2013).
-
(2013)
Fluids Barriers CNS
, vol.10
, pp. 23
-
-
Dohgu, S.1
Banks, W.A.2
-
40
-
-
17444406065
-
Permeability studies on in vitro blood-brain barrier models: Physiology, pathology, and pharmacology
-
Deli, M. A., Abraham, C. R., Kataoka, Y. & Niwa, M. Permeability studies on in vitro blood-brain barrier models: Physiology, pathology, and pharmacology. Cell. Mol. Neurobiol. 25, 59-127 (2005).
-
(2005)
Cell. Mol. Neurobiol.
, vol.25
, pp. 59-127
-
-
Deli, M.A.1
Abraham, C.R.2
Kataoka, Y.3
Niwa, M.4
-
41
-
-
0001816447
-
Neuromethods
-
eds Boulton, A. et al. The Humana Press
-
Johanson, C. E. in Neuromethods; The Neuronal Microenvironment (eds Boulton, A. et al.) 33-104 (The Humana Press, 1988).
-
(1988)
The Neuronal Microenvironment
, pp. 33-104
-
-
Johanson, C.E.1
-
42
-
-
33746290830
-
Release of cytokines by brain endothelial cells: A polarized response to lipopolysaccharide
-
Verma, S., Nakaoke, R., Dohgu, S. & Banks, W. A. Release of cytokines by brain endothelial cells: A polarized response to lipopolysaccharide. Brain Behav. Immun. 20, 449-455 (2006).
-
(2006)
Brain Behav. Immun.
, vol.20
, pp. 449-455
-
-
Verma, S.1
Nakaoke, R.2
Dohgu, S.3
Banks, W.A.4
-
43
-
-
84866745334
-
Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells
-
Engstrom, L. et al. Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells. Endocrinology 153, 4849-4861 (2012).
-
(2012)
Endocrinology
, vol.153
, pp. 4849-4861
-
-
Engstrom, L.1
-
44
-
-
72049083989
-
Minimal penetration of lipopolysaccharide across the murine blood-brain barrier
-
Banks, W. A. & Robinson, S. M. Minimal penetration of lipopolysaccharide across the murine blood-brain barrier. Brain Behav. Immun. 24, 102-109 (2010).
-
(2010)
Brain Behav. Immun.
, vol.24
, pp. 102-109
-
-
Banks, W.A.1
Robinson, S.M.2
-
45
-
-
33646891527
-
Brain uptake of nonsteroidal anti-inflammatory drugs: Ibuprofen, flurbiprofen, and indomethacin
-
Parepally, J. M., Mandula, H. & Smith, Q. R. Brain uptake of nonsteroidal anti-inflammatory drugs: Ibuprofen, flurbiprofen, and indomethacin. Pharm. Res. 23, 873-881 (2006).
-
(2006)
Pharm. Res.
, vol.23
, pp. 873-881
-
-
Parepally, J.M.1
Mandula, H.2
Smith, Q.R.3
-
46
-
-
0023162204
-
Evidence for separate mechanisms of induction of biphasic fever inside and outside the blood-brain barrier
-
Morimoto, A., Murakami, N., Nakamori, T. & Watanabe, T. Evidence for separate mechanisms of induction of biphasic fever inside and outside the blood-brain barrier. J. Physiol. 383, 629-637 (1987).
-
(1987)
J. Physiol.
, vol.383
, pp. 629-637
-
-
Morimoto, A.1
Murakami, N.2
Nakamori, T.3
Watanabe, T.4
-
47
-
-
84875191169
-
Transporters of the blood-brain and blood-CSF interfaces in development and in the adult
-
Saunders, N. R., Daneman, R., Dziegielewska, K. M. & Liddelow, S. A. Transporters of the blood-brain and blood-CSF interfaces in development and in the adult. Mol. Aspects Med. 34, 742-752 (2013).
-
(2013)
Mol. Aspects Med.
, vol.34
, pp. 742-752
-
-
Saunders, N.R.1
Daneman, R.2
Dziegielewska, K.M.3
Liddelow, S.A.4
-
48
-
-
0034089526
-
Fasting but not adrenalectomy, reduces transport of leptin into the brain
-
Kastin, A. J. & Akerstrom, V. Fasting, but not adrenalectomy, reduces transport of leptin into the brain. Peptides 21, 679-682 (2000).
-
(2000)
Peptides
, vol.21
, pp. 679-682
-
-
Kastin, A.J.1
Akerstrom, V.2
-
49
-
-
54149094094
-
Effects of triglycerides, obesity, and starvation on ghrelin transport across the blood-brain barrier
-
Banks, W. A., Burney, B. O. & Robinson, S. M. Effects of triglycerides, obesity, and starvation on ghrelin transport across the blood-brain barrier. Peptides 29, 2061-2065 (2008).
-
(2008)
Peptides
, vol.29
, pp. 2061-2065
-
-
Banks, W.A.1
Burney, B.O.2
Robinson, S.M.3
-
50
-
-
33646103677
-
Receptor-mediated transport of LIF across blood-spinal cord barrier is upregulated after spinal cord injury
-
Pan, W., Cain, C., Yu, Y. & Kastin, A. J. Receptor-mediated transport of LIF across blood-spinal cord barrier is upregulated after spinal cord injury. J. Neuroimmunol. 174, 119-125 (2006).
-
(2006)
J. Neuroimmunol.
, vol.174
, pp. 119-125
-
-
Pan, W.1
Cain, C.2
Yu, Y.3
Kastin, A.J.4
-
51
-
-
32644440951
-
Stroke upregulates TNFα transport across the blood-brain barrier
-
Pan, W. et al. Stroke upregulates TNFα transport across the blood-brain barrier. Exp. Neurol. 198, 222-233 (2006).
-
(2006)
Exp. Neurol.
, vol.198
, pp. 222-233
-
-
Pan, W.1
-
52
-
-
0342955538
-
Effect of middle cerebral artery occulsion on the passage of pituitary adenylate cyclase activating polypeptide across the blood-brain barrier in the rat
-
Somogyvari-Vigh, A., Pan, W., Reglodi, D., Kastin, A. J. & Arimura, A. Effect of middle cerebral artery occulsion on the passage of pituitary adenylate cyclase activating polypeptide across the blood-brain barrier in the rat. Regul. Pept. 91, 89-95 (2000).
-
(2000)
Regul. Pept.
, vol.91
, pp. 89-95
-
-
Somogyvari-Vigh, A.1
Pan, W.2
Reglodi, D.3
Kastin, A.J.4
Arimura, A.5
-
53
-
-
57649244985
-
Neuroinflammation activates Mdr1b efflux transport through NF?B: Promoter analysis in BBB endothelia
-
Yu, C. et al. Neuroinflammation activates Mdr1b efflux transport through NF?B: Promoter analysis in BBB endothelia. Cell Physiol. Biochem. 22, 745-756 (2008).
-
(2008)
Cell Physiol. Biochem.
, vol.22
, pp. 745-756
-
-
Yu, C.1
-
54
-
-
35848952554
-
TNF activates MDR1 (P-glycoprotein) in cerebral microvascular endothelial cells
-
Yu, C., Pan, W., Tu, H., Waters, S. & Kastin, A. J. TNF activates MDR1 (P-glycoprotein) in cerebral microvascular endothelial cells. Cell Physiol. Biochem. 20, 853-858 (2007).
-
(2007)
Cell Physiol. Biochem.
, vol.20
, pp. 853-858
-
-
Yu, C.1
Pan, W.2
Tu, H.3
Waters, S.4
Kastin, A.J.5
-
55
-
-
33847094700
-
Tumor necrosis factor α and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier
-
Bauer, B., Hartz, A. M. S. & Miller, D. S. Tumor necrosis factor α and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier. Mol. Pharmacol. 71, 667-675 (2007).
-
(2007)
Mol. Pharmacol.
, vol.71
, pp. 667-675
-
-
Bauer, B.1
Hartz, A.M.S.2
Miller, D.S.3
-
56
-
-
0028932174
-
The effect of verapamil on the transport of peptides across the blood-brain barrier in rats: Kinetic evidence for an apically polarized efflux mechanism
-
Chikale, E. G., Burton, P. S. & Borchardt, R. T. The effect of verapamil on the transport of peptides across the blood-brain barrier in rats: Kinetic evidence for an apically polarized efflux mechanism. J. Pharmacol. Exp. Ther. 273, 298-303 (1995).
-
(1995)
J. Pharmacol. Exp. Ther.
, vol.273
, pp. 298-303
-
-
Chikale, E.G.1
Burton, P.S.2
Borchardt, R.T.3
-
57
-
-
0029836316
-
Role of P-glycoprotein in the blood-brain transport of colchicine and vinblastine
-
Drion, N., Lemaire, M., Lefauconnier, J. M. & Scherrmann, J. M. Role of P-glycoprotein in the blood-brain transport of colchicine and vinblastine. J. Neurochem. 67, 1688-1693 (1996).
-
(1996)
J. Neurochem.
, vol.67
, pp. 1688-1693
-
-
Drion, N.1
Lemaire, M.2
Lefauconnier, J.M.3
Scherrmann, J.M.4
-
58
-
-
0035957791
-
Enhanced leptin transport across the blood-brain barrier by ?1-adrenergic agents
-
Banks, W. A. Enhanced leptin transport across the blood-brain barrier by ?1-adrenergic agents. Brain Res. 899, 209-217 (2001).
-
(2001)
Brain Res.
, vol.899
, pp. 209-217
-
-
Banks, W.A.1
-
59
-
-
0033010571
-
Enzyme replacement in murine mucopolysaccharidosis type VII: Neuronal and glial response to β-glucuronidase requires early initiation of enzyme replacement therapy
-
Vogler, C. et al. Enzyme replacement in murine mucopolysaccharidosis type VII: Neuronal and glial response to β-glucuronidase requires early initiation of enzyme replacement therapy. Pediatr. Res. 45, 838-844 (1999).
-
(1999)
Pediatr. Res.
, vol.45
, pp. 838-844
-
-
Vogler, C.1
-
60
-
-
34547896622
-
Epinephrine enhances lysosomal enzyme delivery across the blood-brain barrier by up-regulation of the mannose 6-phosphate receptor
-
Urayama, A., Grubb, J. H., Banks, W. A. & Sly, W. S. Epinephrine enhances lysosomal enzyme delivery across the blood-brain barrier by up-regulation of the mannose 6-phosphate receptor. Proc. Natl Acad. Sci. USA 31, 12873-12878 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.31
, pp. 12873-12878
-
-
Urayama, A.1
Grubb, J.H.2
Banks, W.A.3
Sly, W.S.4
-
61
-
-
72049093471
-
COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epilipetic rats
-
Van Vliet, E. A. et al. COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epilipetic rats. Neuropharmacology 58, 404-412 (2010).
-
(2010)
Neuropharmacology
, vol.58
, pp. 404-412
-
-
Van Vliet, E.A.1
-
62
-
-
0036128985
-
Role of multidrug transporters in pharmacoresistance to antiepileptic drugs
-
Loscher, W. & Potschka, H. Role of multidrug transporters in pharmacoresistance to antiepileptic drugs. J. Pharmacol. Exp. Ther. 30, 7-14 (2002).
-
(2002)
J. Pharmacol. Exp. Ther.
, vol.30
, pp. 7-14
-
-
Loscher, W.1
Potschka, H.2
-
63
-
-
38349111108
-
Body weight, plasma insulin, and coronary events with gemfibrozil in the Veterans Affairs High-Density Lipoprotein Intervenation Trial (VA-HIT
-
Robins, S. J., Collins, D., McNamara, J. R. & Bloomfield, H. E. Body weight, plasma insulin, and coronary events with gemfibrozil in the Veterans Affairs High-Density Lipoprotein Intervenation Trial (VA-HIT). Atherosclerosis 196, 849-855 (2007).
-
(2007)
Atherosclerosis
, vol.196
, pp. 849-855
-
-
Robins, S.J.1
Collins, D.2
McNamara, J.R.3
Bloomfield, H.E.4
-
64
-
-
0031867354
-
Nitric oxide production and MDR expression by human brain endothelial cells
-
Mandi, Y. et al. Nitric oxide production and MDR expression by human brain endothelial cells. Anticancer Res. 18, 3049-3052 (1998).
-
(1998)
Anticancer Res.
, vol.18
, pp. 3049-3052
-
-
Mandi, Y.1
-
65
-
-
0037244070
-
Is obesity a disease of the blood-brain barrier? Physiological, pathological, and evolutionary considerations
-
Banks, W. A. Is obesity a disease of the blood-brain barrier? Physiological, pathological, and evolutionary considerations. Curr. Pharm. Design 9, 801-809 (2003).
-
(2003)
Curr. Pharm. Design
, vol.9
, pp. 801-809
-
-
Banks, W.A.1
-
66
-
-
84866686711
-
Neuropathology of the blood-brain barrier and pharmaco-resistance in human epilepsy
-
Liu, J. Y. et al. Neuropathology of the blood-brain barrier and pharmaco-resistance in human epilepsy. Brain 135, 3115-3133 (2012).
-
(2012)
Brain
, vol.135
, pp. 3115-3133
-
-
Liu, J.Y.1
-
67
-
-
84927749696
-
Role of P-glycoprotein in refractoriness of seizures to antiepileptic drugs in Lennox-Gastaut syndrome
-
Kumar, A., Tripathi, D., Paliwal, V. K., Neyaz, Z. & Agarwal, V. Role of P-glycoprotein in refractoriness of seizures to antiepileptic drugs in Lennox-Gastaut syndrome. J. Child Neurol. 30, 223-227 (2014).
-
(2014)
J. Child Neurol.
, vol.30
, pp. 223-227
-
-
Kumar, A.1
Tripathi, D.2
Paliwal, V.K.3
Neyaz, Z.4
Agarwal, V.5
-
68
-
-
0008649345
-
-
eds Greenwood, J et al. Plenum Press
-
Greig, N. H., Brossi, A., Pei, X.-F., Ingram, D. K. & Soncrant, T. T. in New Concepts of a Blood-Brain Barrier (eds Greenwood, J. et al.) 251-264 (Plenum Press, 1995).
-
(1995)
New Concepts of A Blood-Brain Barrier
, pp. 251-264
-
-
Greig, N.H.1
Brossi, A.2
Pei, X.-F.3
Ingram, D.K.4
Soncrant, T.T.5
-
69
-
-
0020187709
-
Comparison of lipid-mediated blood-brain-barrier penetrability in neonates and adults
-
Cornford, E. M., Braun, L. D., Oldendorf, W. H. & Hill, M. A. Comparison of lipid-mediated blood-brain-barrier penetrability in neonates and adults. Am. J. Physiol. 243, C161-C168 (1982).
-
(1982)
Am. J. Physiol.
, vol.243
, pp. 161-168
-
-
Cornford, E.M.1
Braun, L.D.2
Oldendorf, W.H.3
Hill, M.A.4
-
70
-
-
0016354690
-
Lipid solubility and drug penetration of the blood-brain barrier
-
Oldendorf, W. H. Lipid solubility and drug penetration of the blood-brain barrier. Proc. Soc. Exp. Biol. Med. 147, 813-816 (1974).
-
(1974)
Proc. Soc. Exp. Biol. Med.
, vol.147
, pp. 813-816
-
-
Oldendorf, W.H.1
-
71
-
-
33847597534
-
Distribution of drugs between blood and cerebrospinal fluid: General methodology and effect of pH gradients
-
Rall, D. P., Stabenau, J. R. & Zubrod, C. G. Distribution of drugs between blood and cerebrospinal fluid: General methodology and effect of pH gradients. J. Pharmacol. Exp. Ther. 125, 185-193 (1959).
-
(1959)
J. Pharmacol. Exp. Ther.
, vol.125
, pp. 185-193
-
-
Rall, D.P.1
Stabenau, J.R.2
Zubrod, C.G.3
-
72
-
-
0022349214
-
Peptides and the blood-brain barrier: Lipophilicity as a predictor of permeability
-
Banks, W. A. & Kastin, A. J. Peptides and the blood-brain barrier: Lipophilicity as a predictor of permeability. Brain Res. Bull. 15, 287-292 (1985).
-
(1985)
Brain Res. Bull.
, vol.15
, pp. 287-292
-
-
Banks, W.A.1
Kastin, A.J.2
-
73
-
-
0028270064
-
Hydrogen bonding potential as a determinant of the in vitro and in situ blood-brain barrier permeability of peptides
-
Chikhale, E. G., Ng, K. Y., Burton, P. S. & Borchardt, R. T. Hydrogen bonding potential as a determinant of the in vitro and in situ blood-brain barrier permeability of peptides. Pharm. Res. 11, 412-419 (1994).
-
(1994)
Pharm. Res.
, vol.11
, pp. 412-419
-
-
Chikhale, E.G.1
Ng, K.Y.2
Burton, P.S.3
Borchardt, R.T.4
-
74
-
-
0028219636
-
Delta-sleep-inducing peptide: Solution conformational studies of a membrane-permeable peptide
-
Gray, R. A. et al. Delta-sleep-inducing peptide: Solution conformational studies of a membrane-permeable peptide. Biochemistry 33, 1323-1331 (1994).
-
(1994)
Biochemistry
, vol.33
, pp. 1323-1331
-
-
Gray, R.A.1
-
75
-
-
0028277907
-
Strategies for delivery of peptide drugs to the central nervous system: Exploiting molecular structure
-
Begley, D. J. Strategies for delivery of peptide drugs to the central nervous system: Exploiting molecular structure. J. Control. Release 29, 293-306 (1994).
-
(1994)
J. Control. Release
, vol.29
, pp. 293-306
-
-
Begley, D.J.1
-
76
-
-
0027931494
-
Effect of peptidases at the blood brain barrier on the permeability of enkephalin
-
Brownson, E. A., Abbruscato, T. J., Gillespie, T. J., Hruby, V. J. & Davis, T. P. Effect of peptidases at the blood brain barrier on the permeability of enkephalin. J. Pharmacol. Exp. Ther. 270, 675-680 (1994).
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.270
, pp. 675-680
-
-
Brownson, E.A.1
Abbruscato, T.J.2
Gillespie, T.J.3
Hruby, V.J.4
Davis, T.P.5
-
77
-
-
0025107744
-
-
eds Johansson B. B. Owman C. & Widner H. Elsevier
-
Hardebo, J. E. & Owman, C. in Pathophysiology of the Blood-Brain Barrier (eds Johansson, B. B., Owman, C. & Widner, H.) 41-55 (Elsevier, 1990).
-
(1990)
Pathophysiology of the Blood-Brain Barrier
, pp. 41-55
-
-
Hardebo, J.E.1
Owman, C.2
-
78
-
-
0010357791
-
Correlation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity with blood-brain barrier monoamine oxidase activity
-
Kalaria, R. N., Mitchell, M. J. & Harik, S. I. Correlation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity with blood-brain barrier monoamine oxidase activity. Proc. Natl Acad. Sci. USA 84, 3521-3525 (1987).
-
(1987)
Proc. Natl Acad. Sci. USA
, vol.84
, pp. 3521-3525
-
-
Kalaria, R.N.1
Mitchell, M.J.2
Harik, S.I.3
-
79
-
-
0016785856
-
Axonal degeneration associated with a defective blood-brain barrier in cerebral implants
-
Svendgaard, N. A., Bjorklund, A., Hardebo, J. & Stenevi, U. Axonal degeneration associated with a defective blood-brain barrier in cerebral implants. Nature 225, 334-336 (1975).
-
(1975)
Nature
, vol.225
, pp. 334-336
-
-
Svendgaard, N.A.1
Bjorklund, A.2
Hardebo, J.3
Stenevi, U.4
-
80
-
-
0014391753
-
-
eds Lajtha, A. & Ford, D. H. Elsevier
-
Van Gelder, N. M. in Brain Barrier Systems (eds Lajtha, A. & Ford, D. H.) 259-271 (Elsevier, 1968).
-
(1968)
Brain Barrier Systems
, pp. 259-271
-
-
Van Gelder, N.M.1
-
81
-
-
84908447736
-
Myristic acid conjugation of [D-Leu-4]-OB3, a biologically active leptin-related synthetic peptide amide, significantly improves its pharmacokinetic profile and efficacy
-
Novakovic, Z. M., Anderson, B. M. & Grasso, P. Myristic acid conjugation of [D-Leu-4]-OB3, a biologically active leptin-related synthetic peptide amide, significantly improves its pharmacokinetic profile and efficacy. Peptides 62, 176-182 (2014).
-
(2014)
Peptides
, vol.62
, pp. 176-182
-
-
Novakovic, Z.M.1
Anderson, B.M.2
Grasso, P.3
-
82
-
-
40649102937
-
Chemically modified β-glucuronidase crosses blood-brain barrier and clears neuronal storage in murine mucopolysaccharidosis VII
-
Grubb, J. H. et al. Chemically modified β-glucuronidase crosses blood-brain barrier and clears neuronal storage in murine mucopolysaccharidosis VII. Proc. Natl Acad. Sci. USA 105, 2616-2621 (2008).
-
(2008)
Proc. Natl Acad. Sci. USA
, vol.105
, pp. 2616-2621
-
-
Grubb, J.H.1
-
83
-
-
0017671910
-
Net amino acid transport between plasma and erythrocytes and perfused dog brain
-
Drewes, L. R., Conway, W. P. & Gilboe, D. D. Net amino acid transport between plasma and erythrocytes and perfused dog brain. Am. J. Physiol. 2, E320-E325 (1977).
-
(1977)
Am. J. Physiol.
, vol.2
, pp. 320-325
-
-
Drewes, L.R.1
Conway, W.P.2
Gilboe, D.D.3
-
84
-
-
0021396084
-
Red blood cell as glucose carrier: Significance for placental and cerebral glucose transfer
-
Jacquez, J. A. Red blood cell as glucose carrier: Significance for placental and cerebral glucose transfer. Am. J. Physiol. 246, R289-R298 (1984).
-
(1984)
Am. J. Physiol.
, vol.246
, pp. 289-298
-
-
Jacquez, J.A.1
-
85
-
-
84864231131
-
Soluble interleukin-6 receptor induces motor sterotypies and co-localizes with Gp130 in regions linked to cortico-striato-thalamo-cortical circuits
-
Patel, A. et al. Soluble interleukin-6 receptor induces motor sterotypies and co-localizes with Gp130 in regions linked to cortico-striato-thalamo-cortical circuits. PLoS ONE 7, e1623 (2012).
-
(2012)
PLoS ONE
, vol.7
, pp. e1623
-
-
Patel, A.1
-
86
-
-
2442643119
-
Are the extracellular pathways a conduit for the delivery of therapeutics to the brain?
-
Banks, W. A. Are the extracellular pathways a conduit for the delivery of therapeutics to the brain? Curr. Pharm. Design 10, 1365-1370 (2004).
-
(2004)
Curr. Pharm. Design
, vol.10
, pp. 1365-1370
-
-
Banks, W.A.1
-
87
-
-
0027322295
-
Serum proteins bypass the blood-brain barrier for extracellular entry to the central nervous system
-
Broadwell, R. D. & Sofroniew, M. V. Serum proteins bypass the blood-brain barrier for extracellular entry to the central nervous system. Exp. Neurol. 120, 245-263 (1993).
-
(1993)
Exp. Neurol.
, vol.120
, pp. 245-263
-
-
Broadwell, R.D.1
Sofroniew, M.V.2
-
88
-
-
73349086530
-
Investigation of the influence of FcRn on the distribution of IgG to the brain
-
Garg, A. & Balthasar, J. P. Investigation of the influence of FcRn on the distribution of IgG to the brain. AAPS J. 11, 553-557 (2009).
-
(2009)
AAPS J.
, vol.11
, pp. 553-557
-
-
Garg, A.1
Balthasar, J.P.2
-
89
-
-
34447622675
-
Anti-amyloid beta protein antibody passage across the blood-brain barrier in the SAMP8 mouse model of Alzheimer's disease: An age related selective uptake with reversal of learning impairment
-
Banks, W. A. et al. Anti-amyloid beta protein antibody passage across the blood-brain barrier in the SAMP8 mouse model of Alzheimer's disease: An age related selective uptake with reversal of learning impairment. Exp. Neurol. 206, 248-256 (2007).
-
(2007)
Exp. Neurol.
, vol.206
, pp. 248-256
-
-
Banks, W.A.1
-
90
-
-
0022555867
-
Acidification of the endocytic and exocytic pathways
-
Mellman, I., Fuchs, R. & Helenius, A. Acidification of the endocytic and exocytic pathways. Annu. Rev. Biochem. 55, 663-700 (1986).
-
(1986)
Annu. Rev. Biochem.
, vol.55
, pp. 663-700
-
-
Mellman, I.1
Fuchs, R.2
Helenius, A.3
-
91
-
-
0022365637
-
Endothelial negative surface charge areas and blood-brain barrier function
-
Hardebo, J. E. & Kahrstrom, J. Endothelial negative surface charge areas and blood-brain barrier function. Acta Physiol. Scand. 125, 495-499 (1985).
-
(1985)
Acta Physiol. Scand.
, vol.125
, pp. 495-499
-
-
Hardebo, J.E.1
Kahrstrom, J.2
-
92
-
-
0027394873
-
Transcytosis of protein through the mammalian cerebral epithelium and endothelium: II. Adsorptive transcytosis of WGA-HRP and the blood-brain and brain-blood barriers
-
Villegas, J. C. & Broadwell, R. D. Transcytosis of protein through the mammalian cerebral epithelium and endothelium: II. Adsorptive transcytosis of WGA-HRP and the blood-brain and brain-blood barriers. J. Neurocytol. 22, 67-80 (1993).
-
(1993)
J. Neurocytol.
, vol.22
, pp. 67-80
-
-
Villegas, J.C.1
Broadwell, R.D.2
-
93
-
-
0342506835
-
HIV-1 protein gp120 crosses the blood-brain barrier: Role of adsorptive endocytosis
-
Banks, W. A., Kastin, A. J. & Akerstrom, V. HIV-1 protein gp120 crosses the blood-brain barrier: Role of adsorptive endocytosis. Life Sci. 61, L119-L125 (1997).
-
(1997)
Life Sci.
, vol.61
, pp. 119-125
-
-
Banks, W.A.1
Kastin, A.J.2
Akerstrom, V.3
-
94
-
-
0028831865
-
Immunocytochemical studies of protamine-induced blood-brain barrier opening to endogenous albumin
-
Vorbrodt, A. W., Dobrogowska, D. H., Ueno, M. & Lossinsky, A. S. Immunocytochemical studies of protamine-induced blood-brain barrier opening to endogenous albumin. Acta Neuropathol. 89, 491-499 (1995).
-
(1995)
Acta Neuropathol.
, vol.89
, pp. 491-499
-
-
Vorbrodt, A.W.1
Dobrogowska, D.H.2
Ueno, M.3
Lossinsky, A.S.4
-
95
-
-
57149110011
-
CNS delivery via adsorptive transcytosis
-
Herve, F., Ghinea, N. & Scherrmann, J. M. CNS delivery via adsorptive transcytosis. AAPS J. 10, 455-472 (2008).
-
(2008)
AAPS J.
, vol.10
, pp. 455-472
-
-
Herve, F.1
Ghinea, N.2
Scherrmann, J.M.3
-
96
-
-
0025784734
-
Fatty acid acylated Fab-fragments of antibodies to neurospecific proteins as carriers for neuroleptic targeted delivery in brain
-
Chekhonin, V. P., Kabanov, A. V., Zhirkov, Y. A. & Morozov, G. V. Fatty acid acylated Fab-fragments of antibodies to neurospecific proteins as carriers for neuroleptic targeted delivery in brain. FEBS Lett. 287, 149-152 (1991).
-
(1991)
FEBS Lett.
, vol.287
, pp. 149-152
-
-
Chekhonin, V.P.1
Kabanov, A.V.2
Zhirkov, Y.A.3
Morozov, G.V.4
-
97
-
-
77951061675
-
A pharmacologically active monoclonal antibody against the human melanocortin-4 receptor: Effectiveness after peripheral and central administration
-
Peter, J. C. et al. A pharmacologically active monoclonal antibody against the human melanocortin-4 receptor: Effectiveness after peripheral and central administration. J. Pharmacol. Exp. Ther. 333, 478-490 (2010).
-
(2010)
J. Pharmacol. Exp. Ther.
, vol.333
, pp. 478-490
-
-
Peter, J.C.1
-
98
-
-
0031965788
-
Outwitting the blood-brain barrier for therapeutic purposes: Osmotic opening and other means
-
Kroll, R. A. & Neuwelt, E. A. Outwitting the blood-brain barrier for therapeutic purposes: Osmotic opening and other means. Neurosurgery 42, 1083-1099 (1998).
-
(1998)
Neurosurgery
, vol.42
, pp. 1083-1099
-
-
Kroll, R.A.1
Neuwelt, E.A.2
-
99
-
-
84897003566
-
Recent progress in tight junction modulation for improving bioavailability
-
Saaber, D., Wollenhaupt, S., Baumann, K. & Reichl, S. Recent progress in tight junction modulation for improving bioavailability. Expert Opin. Drug Deliv. 9, 347-381 (2014).
-
(2014)
Expert Opin. Drug Deliv.
, vol.9
, pp. 347-381
-
-
Saaber, D.1
Wollenhaupt, S.2
Baumann, K.3
Reichl, S.4
-
100
-
-
77954940188
-
Central nervous system penetration for small molecule therapeutic agents does not increase in multiple sclerosis- and Alzheimer's disease-related animal models despite reported blood-brain barrier disruption
-
Cheng, Z. et al. Central nervous system penetration for small molecule therapeutic agents does not increase in multiple sclerosis- and Alzheimer's disease-related animal models despite reported blood-brain barrier disruption. Drug Metab. Dispos. 38, 135-161 (2010).
-
(2010)
Drug Metab. Dispos.
, vol.38
, pp. 135-161
-
-
Cheng, Z.1
-
101
-
-
0026195861
-
Osmotic-hypertensive opening of the blood-brain barrier in rats does not necessarily provide access for potassium to cerebral interstitial fluid
-
Somjen, G. G., Segal, M. B. & Herreras, O. Osmotic-hypertensive opening of the blood-brain barrier in rats does not necessarily provide access for potassium to cerebral interstitial fluid. Exp. Physiol. 76, 507-514 (1991).
-
(1991)
Exp. Physiol.
, vol.76
, pp. 507-514
-
-
Somjen, G.G.1
Segal, M.B.2
Herreras, O.3
-
102
-
-
84876288324
-
Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease
-
Sengillo, J. D. et al. Deficiency in mural vascular cells coincides with blood-brain barrier disruption in Alzheimer's disease. Brain Pathol. 23, 303-310 (2012).
-
(2012)
Brain Pathol.
, vol.23
, pp. 303-310
-
-
Sengillo, J.D.1
-
103
-
-
84455185110
-
Topiramate treatment protects blood-brain barrier pericytes from hyperglycemia-induced oxidative damage in diabetic mice
-
Price, T. O., Eranki, V., Banks, W. A., Ercal, N. & Shah, G. N. Topiramate treatment protects blood-brain barrier pericytes from hyperglycemia-induced oxidative damage in diabetic mice. Endocrinology 153, 362-372 (2012).
-
(2012)
Endocrinology
, vol.153
, pp. 362-372
-
-
Price, T.O.1
Eranki, V.2
Banks, W.A.3
Ercal, N.4
Shah, G.N.5
-
104
-
-
0036789145
-
Pericytes and the pathogenesis of diabetic retinopathy
-
Hammes, H. P. et al. Pericytes and the pathogenesis of diabetic retinopathy. Diabetes 51, 3107-3112 (2002).
-
(2002)
Diabetes
, vol.51
, pp. 3107-3112
-
-
Hammes, H.P.1
-
105
-
-
4344692314
-
Inflammatory changes and breakdown of microvascular integrity in early human immunodeficiency virus dementia
-
Avison, M. J. et al. Inflammatory changes and breakdown of microvascular integrity in early human immunodeficiency virus dementia. J. Neurovirol. 10, 223-232 (2004).
-
(2004)
J. Neurovirol.
, vol.10
, pp. 223-232
-
-
Avison, M.J.1
-
106
-
-
0033866453
-
Monocytes infiltration is highly associated with loss of tight junction protein zonula occludens in HIV-1-associated dementia
-
Boven, L. A., Middel, J., Verhoef, J., De Groot, C. J. & Nottet, H. S. Monocytes infiltration is highly associated with loss of tight junction protein zonula occludens in HIV-1-associated dementia. Neuropathol. Appl. Neurobiol. 26, 356-362 (2000).
-
(2000)
Neuropathol. Appl. Neurobiol.
, vol.26
, pp. 356-362
-
-
Boven, L.A.1
Middel, J.2
Verhoef, J.3
De Groot, C.J.4
Nottet, H.S.5
-
107
-
-
0020607493
-
Ultracytochemical studies of vesicular and canalicular transport structures in the injured mammalian blood-brain barrier
-
Lossinsky, A. S., Vorbrodt, A. W. & Wisniewski, H. M. Ultracytochemical studies of vesicular and canalicular transport structures in the injured mammalian blood-brain barrier. Acta Neuropathol. 61, 239-245 (1983).
-
(1983)
Acta Neuropathol.
, vol.61
, pp. 239-245
-
-
Lossinsky, A.S.1
Vorbrodt, A.W.2
Wisniewski, H.M.3
-
108
-
-
0023694127
-
Mediators of blood-brain barrier dysfunction and formation of vasogenic brain edema
-
Wahl, M., Unterberg, A., Baethmann, A. & Schilling, L. Mediators of blood-brain barrier dysfunction and formation of vasogenic brain edema. J. Cereb. Blood Flow Metab. 8, 621-634 (1988).
-
(1988)
J. Cereb. Blood Flow Metab.
, vol.8
, pp. 621-634
-
-
Wahl, M.1
Unterberg, A.2
Baethmann, A.3
Schilling, L.4
-
109
-
-
70349319841
-
ENOS gene deletion restores blood-brain barrier integrity and attenuates neurodegeneration in the thiamine-deficient mouse brain
-
Beauchesne, E., Desjardins, P., Hazell, A. S. & Butterworth, R. F. eNOS gene deletion restores blood-brain barrier integrity and attenuates neurodegeneration in the thiamine-deficient mouse brain. J. Neurochem. 111, 425-459 (2009).
-
(2009)
J. Neurochem.
, vol.111
, pp. 425-459
-
-
Beauchesne, E.1
Desjardins, P.2
Hazell, A.S.3
Butterworth, R.F.4
-
110
-
-
84883796045
-
Relationship between cyclophilin A levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein E4 carriers and blood-brain barrier breakdown
-
Halliday, M. R. et al. Relationship between cyclophilin A levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein E4 carriers and blood-brain barrier breakdown. JAMA 70, 1198-1200 (2013).
-
(2013)
JAMA
, vol.70
, pp. 1198-1200
-
-
Halliday, M.R.1
-
111
-
-
84874442369
-
Pharmacological inhibition of mitochondrial carbonic anhydrases protects mouse cerebral pericytes from high glucose-induced oxidative stress and apoptosis
-
Shah, G. N. et al. Pharmacological inhibition of mitochondrial carbonic anhydrases protects mouse cerebral pericytes from high glucose-induced oxidative stress and apoptosis. J. Pharmacol. Exp. Ther. 344, 637-645 (2013).
-
(2013)
J. Pharmacol. Exp. Ther.
, vol.344
, pp. 637-645
-
-
Shah, G.N.1
-
112
-
-
35549002772
-
Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-α in the rat
-
Candelario-Jalil, E. et al. Cyclooxygenase inhibition limits blood-brain barrier disruption following intracerebral injection of tumor necrosis factor-α in the rat. J. Pharmacol. Exp. Ther. 323, 488-498 (2007).
-
(2007)
J. Pharmacol. Exp. Ther.
, vol.323
, pp. 488-498
-
-
Candelario-Jalil, E.1
-
113
-
-
84861566618
-
Pegylated granulocyte colony-stimultating factor conveys long-term neuroprotection and improves functional outcome in a model of Parkinson's disease
-
Frank, T. et al. Pegylated granulocyte colony-stimultating factor conveys long-term neuroprotection and improves functional outcome in a model of Parkinson's disease. Brain 135, 1914-1925 (2012).
-
(2012)
Brain
, vol.135
, pp. 1914-1925
-
-
Frank, T.1
-
114
-
-
24144479258
-
Glycosylated neuropeptides: A new vista for neuropsychopharmacology
-
Polt, R., Dhanasekaran, M. & Keyari, C. M. Glycosylated neuropeptides: A new vista for neuropsychopharmacology. Med. Res. Rev. 25, 557-585 (2005).
-
(2005)
Med. Res. Rev.
, vol.25
, pp. 557-585
-
-
Polt, R.1
Dhanasekaran, M.2
Keyari, C.M.3
-
115
-
-
79952916450
-
Cell-mediated drug delivery
-
Batrakova, E. V., Gendelman, H. E. & Kabanov, A. V. Cell-mediated drug delivery. Expert Opin. Drug Deliv. 8, 415-433 (2011).
-
(2011)
Expert Opin. Drug Deliv.
, vol.8
, pp. 415-433
-
-
Batrakova, E.V.1
Gendelman, H.E.2
Kabanov, A.V.3
-
116
-
-
84895455959
-
Effectve intravenous therapy for neurodegenerative disease with a therapeutic enzyme and a peptide that mediates delivery to the brain
-
Meng, Y. et al. Effectve intravenous therapy for neurodegenerative disease with a therapeutic enzyme and a peptide that mediates delivery to the brain. Mol. Ther. 22, 547-543 (2014).
-
(2014)
Mol. Ther.
, vol.22
, pp. 547-543
-
-
Meng, Y.1
-
117
-
-
84887223983
-
Brain delivery of proteins via their fatty acid and block copolymer modifications
-
Yi, X. & Kabanov, A. V. Brain delivery of proteins via their fatty acid and block copolymer modifications. J. Drug Target. 21, 940-955 (2013).
-
(2013)
J. Drug Target.
, vol.21
, pp. 940-955
-
-
Yi, X.1
Kabanov, A.V.2
-
118
-
-
0025819954
-
Defective glucose transport across the blood-brain barrier as a cause of persistent hypoglycorrhachia, seizures, and developmental delay
-
De Vivo, D. C. et al. Defective glucose transport across the blood-brain barrier as a cause of persistent hypoglycorrhachia, seizures, and developmental delay. N. Engl. J. Med. 325, 703-709 (1991).
-
(1991)
N. Engl. J. Med.
, vol.325
, pp. 703-709
-
-
De Vivo, D.C.1
-
119
-
-
84885018413
-
Blood-brain barrier dysfunction as a cause and consequence of Alzheimer's disease
-
Erickson, M. A. & Banks, W. A. Blood-brain barrier dysfunction as a cause and consequence of Alzheimer's disease. J. Cereb. Blood Flow Metab. 33, 1500-1513 (2013).
-
(2013)
J. Cereb. Blood Flow Metab.
, vol.33
, pp. 1500-1513
-
-
Erickson, M.A.1
Banks, W.A.2
-
120
-
-
0032896034
-
Contribution of extracranial lymphatics and arachnoid villi to the clearance of a CSF tracer in the rat
-
Boulton, M. et al. Contribution of extracranial lymphatics and arachnoid villi to the clearance of a CSF tracer in the rat. Am. J. Physiol. 276, R818-R823 (1999).
-
(1999)
Am. J. Physiol.
, vol.276
, pp. 818-823
-
-
Boulton, M.1
-
121
-
-
0023237250
-
Blood-brain barrier in Alzheimer dementia and in non-demented elderly
-
Alafuzoff, I., Adolfsson, R., Grundke-Iqbal, I. & Winblad, B. Blood-brain barrier in Alzheimer dementia and in non-demented elderly. Acta Neuropathol. 73, 160-166 (1987).
-
(1987)
Acta Neuropathol.
, vol.73
, pp. 160-166
-
-
Alafuzoff, I.1
Adolfsson, R.2
Grundke-Iqbal, I.3
Winblad, B.4
-
122
-
-
84865123660
-
A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid ?
-
Iliff, J. J. et al. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid ?. Sci. Transl Med. 4, 147ra111 (2012).
-
(2012)
Sci. Transl Med.
, vol.4
, pp. 147-211
-
-
Iliff, J.J.1
-
123
-
-
84863005570
-
Lipopolysaccharide impairs amyloid ? Efflux from brain: Altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood-brain barrier
-
Erickson, M. A. et al. Lipopolysaccharide impairs amyloid ? efflux from brain: Altered vascular sequestration, cerebrospinal fluid reabsorption, peripheral clearance and transporter function at the blood-brain barrier. J. Neuroinflamm. 9, 150 (2012).
-
(2012)
J. Neuroinflamm.
, vol.9
, pp. 150
-
-
Erickson, M.A.1
-
124
-
-
79953075804
-
Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease
-
Grammas, P. Neurovascular dysfunction, inflammation and endothelial activation: Implications for the pathogenesis of Alzheimer's disease. J. Neuroinflammation 8, 26 (2011).
-
(2011)
J. Neuroinflammation
, vol.8
, pp. 26
-
-
Grammas, P.1
-
125
-
-
13544268809
-
Neurovascular mechanisms of Alzheimer's neurodegeneration
-
Zlokovic, B. V. Neurovascular mechanisms of Alzheimer's neurodegeneration. Trends Neurosci. 28, 202-208 (2005).
-
(2005)
Trends Neurosci.
, vol.28
, pp. 202-208
-
-
Zlokovic, B.V.1
-
126
-
-
78149255128
-
Low density lipoprotein receptor related protein-1: A serial clearance homeostatic mechanism controlling Alzheimer's amyloid ?-peptide elimination fromt the brain
-
Zlokovic, B. V., Deane, R., Sagare, A. P., Bell, R. D. & Winkler, E. A. Low density lipoprotein receptor related protein-1: A serial clearance homeostatic mechanism controlling Alzheimer's amyloid ?-peptide elimination fromt the brain. J. Neurochem. 115, 1077-1089 (2010).
-
(2010)
J. Neurochem.
, vol.115
, pp. 1077-1089
-
-
Zlokovic, B.V.1
Deane, R.2
Sagare, A.P.3
Bell, R.D.4
Winkler, E.A.5
-
127
-
-
77951078680
-
Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-? in a mouse model of Alzheimer's disease
-
Hartz, A. M. S., Miller, D. S. & Bauer, B. Restoring blood-brain barrier P-glycoprotein reduces brain amyloid-? in a mouse model of Alzheimer's disease. Mol. Pharmacol. 77, 715-723 (2010).
-
(2010)
Mol. Pharmacol.
, vol.77
, pp. 715-723
-
-
Hartz, A.M.S.1
Miller, D.S.2
Bauer, B.3
-
128
-
-
33749157416
-
RAGE LRP-1 and amyloid-beta protein in Alzheimer's disease
-
Donahue, J. E. et al. RAGE, LRP-1, and amyloid-beta protein in Alzheimer's disease. Acta Neuropathol. 112, 405-415 (2006).
-
(2006)
Acta Neuropathol.
, vol.112
, pp. 405-415
-
-
Donahue, J.E.1
-
129
-
-
77957352509
-
ABC efflux transporters in brain vasculature of Alzheimer's subjects
-
Wijesuriya, J. C., Bullock, J. Y., Faull, R. L. M., Hladky, S. B. & Barrand, M. A. ABC efflux transporters in brain vasculature of Alzheimer's subjects. Brain Res. 1358, 228-238 (2010).
-
(2010)
Brain Res.
, vol.1358
, pp. 228-238
-
-
Wijesuriya, J.C.1
Bullock, J.Y.2
Faull, R.L.M.3
Hladky, S.B.4
Barrand, M.A.5
-
130
-
-
78049386757
-
Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer's disease: Implications for A? Accumulation in AD brain
-
Owen, J. B. et al. Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer's disease: Implications for A? accumulation in AD brain. Free Radic. Biol. Med. 49, 1798-1803 (2010).
-
(2010)
Free Radic. Biol. Med.
, vol.49
, pp. 1798-1803
-
-
Owen, J.B.1
-
131
-
-
84863393540
-
Blood-brain barrier P-glycoprotein function in Alzheimer's disease
-
Van Assema, D. M. et al. Blood-brain barrier P-glycoprotein function in Alzheimer's disease. Brain 135, 181-189 (2012).
-
(2012)
Brain
, vol.135
, pp. 181-189
-
-
Van Assema, D.M.1
-
132
-
-
67849099661
-
Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-β protein, and impairs cognition
-
Jaeger, L. B. et al. Testing the neurovascular hypothesis of Alzheimer's disease: LRP-1 antisense reduces blood-brain barrier clearance, increases brain levels of amyloid-β protein, and impairs cognition. J. Alzheimers Dis. 17, 553-570 (2009).
-
(2009)
J. Alzheimers Dis.
, vol.17
, pp. 553-570
-
-
Jaeger, L.B.1
-
133
-
-
12844266117
-
The critical role of methionine 35 in Alzheimer's amyloid ? Peptide (1-42)-induced oxidative stress and neurotoxicity
-
Butterfield, D. A. & Boyd-Kimball, D. The critical role of methionine 35 in Alzheimer's amyloid ? peptide (1-42)-induced oxidative stress and neurotoxicity. Biochim. Biophys. Acta 1703, 149-156 (2005).
-
(2005)
Biochim. Biophys. Acta
, vol.1703
, pp. 149-156
-
-
Butterfield, D.A.1
Boyd-Kimball, D.2
-
134
-
-
79953282242
-
Impairments in brain-to-blood transport of amyloid-β and reabsorption of cerebrospinal fluid in an animal model of Alzheimer's disease are reversed by antisense directed against amyloid-β protein precursor
-
Banks, W. A. et al. Impairments in brain-to-blood transport of amyloid-β and reabsorption of cerebrospinal fluid in an animal model of Alzheimer's disease are reversed by antisense directed against amyloid-β protein precursor. J. Alzheimers Dis. 23, 599-605 (2011).
-
(2011)
J. Alzheimers Dis.
, vol.23
, pp. 599-605
-
-
Banks, W.A.1
-
135
-
-
84890576583
-
Pericyte loss influences Alzheimer-like neurodegeneration in mice
-
Sagare, A. P. et al. Pericyte loss influences Alzheimer-like neurodegeneration in mice. Nature Commun. 4, 2932 (2013).
-
(2013)
Nature Commun.
, vol.4
, pp. 2932
-
-
Sagare, A.P.1
-
136
-
-
0031907459
-
Cerebrosinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein e genotype
-
Craft, S. et al. Cerebrosinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein E genotype. Neurology 50, 164-168 (1998).
-
(1998)
Neurology
, vol.50
, pp. 164-168
-
-
Craft, S.1
-
137
-
-
84859718265
-
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dyregulation, and cognitive decline
-
Talbot, K. et al. Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dyregulation, and cognitive decline. J. Clin. Invest. 122, 1316-1338 (2012).
-
(2012)
J. Clin. Invest.
, vol.122
, pp. 1316-1338
-
-
Talbot, K.1
-
138
-
-
47849123972
-
Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-? in memory-impaired older adults
-
Reger, M. A. et al. Intranasal insulin administration dose-dependently modulates verbal memory and plasma amyloid-? in memory-impaired older adults. J. Alzheimers Dis. 13, 323-331 (2008).
-
(2008)
J. Alzheimers Dis.
, vol.13
, pp. 323-331
-
-
Reger, M.A.1
-
139
-
-
46349086692
-
Starvation and triglycerides reverse the obesity-induced impairment of insulin transport at the blood-brain barrier
-
Urayama, A. & Banks, W. A. Starvation and triglycerides reverse the obesity-induced impairment of insulin transport at the blood-brain barrier. Endocrinology 149, 3592-3597 (2008).
-
(2008)
Endocrinology
, vol.149
, pp. 3592-3597
-
-
Urayama, A.1
Banks, W.A.2
-
140
-
-
34547828083
-
Interactions between'cognitive' and 'metabolic' brain in the control of food intake
-
Berthoud, H. R. Interactions between 'cognitive' and 'metabolic' brain in the control of food intake. Physiol. Behav. 91, 486-498 (2007).
-
(2007)
Physiol. Behav.
, vol.91
, pp. 486-498
-
-
Berthoud, H.R.1
-
141
-
-
0025848234
-
Mononuclear cell trafficking and plasma protein extravasation into the CNS during chronic relapsing experimental allergic encephalomyelitis in Biozzi AB/H mice
-
Butter, C., Baker, D., O'Neill, J. K. & Turk, J. L. Mononuclear cell trafficking and plasma protein extravasation into the CNS during chronic relapsing experimental allergic encephalomyelitis in Biozzi AB/H mice. J. Neurol. Sci. 104, 9-12 (1991).
-
(1991)
J. Neurol. Sci.
, vol.104
, pp. 9-12
-
-
Butter, C.1
Baker, D.2
O'Neill, J.K.3
Turk, J.L.4
-
142
-
-
69549127961
-
Cessation of blood-to-brain influx of interleukin-15 during development of EAE
-
Hsuchou, H., Pan, W., Wu, X. & Kastin, A. J. Cessation of blood-to-brain influx of interleukin-15 during development of EAE. J. Cereb. Blood Flow Metab. 29, 1568-1578 (2009).
-
(2009)
J. Cereb. Blood Flow Metab.
, vol.29
, pp. 1568-1578
-
-
Hsuchou, H.1
Pan, W.2
Wu, X.3
Kastin, A.J.4
-
143
-
-
0021164553
-
Blood-brain and blood-spinal cord barrier permeability during the course of experimental allergic encephalomyelitis in the rat
-
Juhler, M. et al. Blood-brain and blood-spinal cord barrier permeability during the course of experimental allergic encephalomyelitis in the rat. Brain Res. 302, 347-355 (1984).
-
(1984)
Brain Res.
, vol.302
, pp. 347-355
-
-
Juhler, M.1
-
144
-
-
84885040008
-
Loss of astrocytic leptin signaling worsens experimental autoimmune encephalomyelitis
-
Mishra, P. K. et al. Loss of astrocytic leptin signaling worsens experimental autoimmune encephalomyelitis. Brain Behav. Immun. 34, 98-107 (2013).
-
(2013)
Brain Behav. Immun.
, vol.34
, pp. 98-107
-
-
Mishra, P.K.1
-
145
-
-
26244449275
-
Astrocytes and microglia differentially regulate trafficking of lymphocyte subsets across brain endothelial cells
-
Hudson, L. C., Bragg, D. C., Tompkins, M. B. & Meeker, R. B. Astrocytes and microglia differentially regulate trafficking of lymphocyte subsets across brain endothelial cells. Brain Res. 1058, 148-160 (2005).
-
(2005)
Brain Res.
, vol.1058
, pp. 148-160
-
-
Hudson, L.C.1
Bragg, D.C.2
Tompkins, M.B.3
Meeker, R.B.4
-
146
-
-
53049107590
-
The effects of natalizumab on the innate and adaptive immune system in the central nervous system
-
Stuve, O. The effects of natalizumab on the innate and adaptive immune system in the central nervous system. J. Neurol. Sci. 274, 39-41 (2008).
-
(2008)
J. Neurol. Sci.
, vol.274
, pp. 39-41
-
-
Stuve, O.1
-
147
-
-
34250315324
-
The blood-brain barrier in multiple sclerosis: Functional roles and therapeutic targeting
-
Correale, J. & Villa, A. The blood-brain barrier in multiple sclerosis: Functional roles and therapeutic targeting. Autoimmunity 40, 148-160 (2007).
-
(2007)
Autoimmunity
, vol.40
, pp. 148-160
-
-
Correale, J.1
Villa, A.2
-
148
-
-
65449183851
-
Targeting the CNS to treat type 2 diabetes
-
Sandoval, D. A., Obici, S. & Seeley, R. J. Targeting the CNS to treat type 2 diabetes. Nat. Rev. Drug Discov. 8, 386-398 (2009).
-
(2009)
Nat. Rev. Drug Discov.
, vol.8
, pp. 386-398
-
-
Sandoval, D.A.1
Obici, S.2
Seeley, R.J.3
-
149
-
-
79551506567
-
Brain insulin controls adipose tissue lipolysis and lipogenesis
-
Scherer, T. et al. Brain insulin controls adipose tissue lipolysis and lipogenesis. Cell Metab. 13, 183-194 (2011).
-
(2011)
Cell Metab.
, vol.13
, pp. 183-194
-
-
Scherer, T.1
-
150
-
-
0032763709
-
Impaired transport of leptin across the blood-brain barrier in obesity
-
Banks, W. A., DiPalma, C. R. & Farrell, C. L. Impaired transport of leptin across the blood-brain barrier in obesity. Peptides 20, 1341-1345 (1999).
-
(1999)
Peptides
, vol.20
, pp. 1341-1345
-
-
Banks, W.A.1
DiPalma, C.R.2
Farrell, C.L.3
-
151
-
-
0036306098
-
Activation of nuclear factor-?B induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes
-
Romeo, G., Liu, W. H., Asnaghi, V., Kern, T. S. & Lorenzi, M. Activation of nuclear factor-?B induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes. Diabetes 51, 2241-2248 (2002).
-
(2002)
Diabetes
, vol.51
, pp. 2241-2248
-
-
Romeo, G.1
Liu, W.H.2
Asnaghi, V.3
Kern, T.S.4
Lorenzi, M.5
-
152
-
-
33845397903
-
Streptozotocin-induced diabetes progressively increases blood-brain barrier permeability in specific brain regions in rats
-
Huber, J. D., VanGilder, R. L. & Houser, K. A. Streptozotocin-induced diabetes progressively increases blood-brain barrier permeability in specific brain regions in rats. Am. J. Physiol. 291, H2660-H2668 (2006).
-
(2006)
Am. J. Physiol.
, vol.291
, pp. 2660-2668
-
-
Huber, J.D.1
VanGilder, R.L.2
Houser, K.A.3
-
153
-
-
0037228838
-
Increased blood-brain barrier permeability in type II diabetes demonstrated by gadolinium magnetic resonance imaging
-
Starr, J. M. et al. Increased blood-brain barrier permeability in type II diabetes demonstrated by gadolinium magnetic resonance imaging. J. Neurol. Neurosurg. Psychiatry 74, 70-76 (2003).
-
(2003)
J. Neurol. Neurosurg. Psychiatry
, vol.74
, pp. 70-76
-
-
Starr, J.M.1
-
154
-
-
84885867527
-
High glucose-induced mitochondrial resistance and reactive oxygen species in mouse cerebral pericytes is reversed by pharmacological inhibition of mitochondrial carbonic anhydrase: Implications for cerbral microvascular disease in diabetes
-
Shah, G. N., Morofuji, Y., Banks, W. A. & Price, T. O. High glucose-induced mitochondrial resistance and reactive oxygen species in mouse cerebral pericytes is reversed by pharmacological inhibition of mitochondrial carbonic anhydrase: Implications for cerbral microvascular disease in diabetes. Biochem. Biophys. Res. Commun. 440, 354-358 (2013).
-
(2013)
Biochem. Biophys. Res. Commun.
, vol.440
, pp. 354-358
-
-
Shah, G.N.1
Morofuji, Y.2
Banks, W.A.3
Price, T.O.4
-
155
-
-
28844466951
-
Diabetic retinopathy: Mitochondrial dysfunction and retinal capillary cell death
-
Kowluru, R. A. Diabetic retinopathy: Mitochondrial dysfunction and retinal capillary cell death. Antioxid. Redox Signal. 7, 1581-1587 (2005).
-
(2005)
Antioxid. Redox Signal.
, vol.7
, pp. 1581-1587
-
-
Kowluru, R.A.1
-
156
-
-
70450225361
-
Targeting carbonic anhydrase to treat diabetic retinopathy: Emerging evidences and encouraging results
-
Weiwei, Z. & Hu, R. Targeting carbonic anhydrase to treat diabetic retinopathy: Emerging evidences and encouraging results. Biochem. Biophys. Res. Commun. 390, 368-371 (2009).
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.390
, pp. 368-371
-
-
Weiwei, Z.1
Hu, R.2
-
157
-
-
2342449315
-
Triglycerides induce leptin resistance at the blood-brain barrier
-
Banks, W. A. et al. Triglycerides induce leptin resistance at the blood-brain barrier. Diabetes 53, 1253-1260 (2004).
-
(2004)
Diabetes
, vol.53
, pp. 1253-1260
-
-
Banks, W.A.1
-
158
-
-
0035016703
-
Glucose and insulin increase the transport of leptin through the blood-brain barrier in normal mice but not in streptozotocin-diabetic mice
-
Kastin, A. J. & Akerstrom, V. Glucose and insulin increase the transport of leptin through the blood-brain barrier in normal mice but not in streptozotocin-diabetic mice. Neuroendocrinology 73, 237-242 (2001).
-
(2001)
Neuroendocrinology
, vol.73
, pp. 237-242
-
-
Kastin, A.J.1
Akerstrom, V.2
-
159
-
-
84856269555
-
1α,25-dihydroxyvitam D3 enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier
-
Ito, S. et al. 1α,25-dihydroxyvitam D3 enhances cerebral clearance of human amyloid-β peptide(1-40) from mouse brain across the blood-brain barrier. Fluids Barriers CNS 8, 20 (2011).
-
(2011)
Fluids Barriers CNS
, vol.8
, pp. 20
-
-
Ito, S.1
-
160
-
-
84872653661
-
The effect of rosiglitazone on LRP1 expression and amyloid ? Uptake in human brain microvascular endothelial cells: A possible role of a low-dose thiazolidinedione for dementia treatment
-
Moon, J. H. et al. The effect of rosiglitazone on LRP1 expression and amyloid ? uptake in human brain microvascular endothelial cells: A possible role of a low-dose thiazolidinedione for dementia treatment. Int. J. Neuropsychopharmacol. 1, 1-8 (2011).
-
(2011)
Int. J. Neuropsychopharmacol.
, vol.1
, pp. 1-8
-
-
Moon, J.H.1
-
161
-
-
33749033087
-
Estradiol reduces activity of the blood-brain barrier Na-K-Cl cotransporter and decreases edema formation in permenent middle cerebral artery occlusion
-
O'Donnell, M. E., Lam, T. I., Tran, L. Q., Foroutan, S. & Anderson, S. E. Estradiol reduces activity of the blood-brain barrier Na-K-Cl cotransporter and decreases edema formation in permenent middle cerebral artery occlusion. J. Cereb. Blood Flow Metab. 26, 1234-1249 (2006).
-
(2006)
J. Cereb. Blood Flow Metab.
, vol.26
, pp. 1234-1249
-
-
O'Donnell, M.E.1
Lam, T.I.2
Tran, L.Q.3
Foroutan, S.4
Anderson, S.E.5
-
162
-
-
84891884106
-
Phase 1 safety, tolerability and pharmacokinetics of 3K3A-APC in healthy adult vounteers
-
Lyden, P. et al. Phase 1 safety, tolerability and pharmacokinetics of 3K3A-APC in healthy adult vounteers. Curr. Pharm. Design 19, 7479-7485 (2013).
-
(2013)
Curr. Pharm. Design
, vol.19
, pp. 7479-7485
-
-
Lyden, P.1
-
163
-
-
0344837293
-
Release of prostaglandin E-2 in bovine brain endothelial cells after exposure to three unique forms of the antifungal drug amphotericin-B: Role of COX-2 in amphotericin-B induced fever
-
McGuire, T. R. et al. Release of prostaglandin E-2 in bovine brain endothelial cells after exposure to three unique forms of the antifungal drug amphotericin-B: Role of COX-2 in amphotericin-B induced fever. Life Sci. 72, 2581-2590 (2003).
-
(2003)
Life Sci.
, vol.72
, pp. 2581-2590
-
-
McGuire, T.R.1
-
164
-
-
33749049130
-
Evidence that N-acetylcysteine inhibits TNF-κ-induced cerebrovascular endothelin-1 upregulation via inhibition of mitogen- and stress-activated protein kinase
-
Sury, M. D. et al. Evidence that N-acetylcysteine inhibits TNF-κ-induced cerebrovascular endothelin-1 upregulation via inhibition of mitogen- and stress-activated protein kinase. Free Radic. Biol. Med. 41, 1372-1383 (2006).
-
(2006)
Free Radic. Biol. Med.
, vol.41
, pp. 1372-1383
-
-
Sury, M.D.1
-
165
-
-
0037007826
-
HIV-1-induced production of endothelin-1 in an in vitro model of the human blood-brain barrier
-
Didier, N., Banks, W. A., Creminon, C., Dereuddre-Bosquet, N. & Mabondzo, A. HIV-1-induced production of endothelin-1 in an in vitro model of the human blood-brain barrier. Neuroreport 13, 1179-1183 (2002).
-
(2002)
Neuroreport
, vol.13
, pp. 1179-1183
-
-
Didier, N.1
Banks, W.A.2
Creminon, C.3
Dereuddre-Bosquet, N.4
Mabondzo, A.5
-
166
-
-
0032881899
-
Endothelin-1 elevated in the cerebrospinal fluid of HIV-infected patients with encephalopathy
-
Rolinski, B. et al. Endothelin-1 elevated in the cerebrospinal fluid of HIV-infected patients with encephalopathy. Infection 27, 244-247 (1999).
-
(1999)
Infection
, vol.27
, pp. 244-247
-
-
Rolinski, B.1
-
167
-
-
79955599523
-
Targeting the neurovascular unit for treatment of neurological disorders
-
Vangilder, R. L., Rosen, C. L., Barr, T. L. & Huber, J. D. Targeting the neurovascular unit for treatment of neurological disorders. Pharmacol. Ther. 130, 239-247 (2011).
-
(2011)
Pharmacol. Ther.
, vol.130
, pp. 239-247
-
-
Vangilder, R.L.1
Rosen, C.L.2
Barr, T.L.3
Huber, J.D.4
-
168
-
-
84879424201
-
Immune activation of human brain microvascular endothelial cells inhibits HIV replication in macrophages
-
Li, J. et al. Immune activation of human brain microvascular endothelial cells inhibits HIV replication in macrophages. Blood 121, 2934-2942 (2013).
-
(2013)
Blood
, vol.121
, pp. 2934-2942
-
-
Li, J.1
-
169
-
-
85025413683
-
Studies on the relationship of the chemical constituents of blood and cerebrospinal fluid
-
Kubie, L. S. & Shults, G. M. Studies on the relationship of the chemical constituents of blood and cerebrospinal fluid. J. Exp. Med. 42, 565-591 (1925).
-
(1925)
J. Exp. Med.
, vol.42
, pp. 565-591
-
-
Kubie, L.S.1
Shults, G.M.2
-
170
-
-
84962253590
-
Comparative study of the concentration of various anions and cations in cerebrospinal fluid and serum
-
Pincus, J. B. & Kramer, B. Comparative study of the concentration of various anions and cations in cerebrospinal fluid and serum. J. Biol. Chem. 57, 463-470 (1923).
-
(1923)
J. Biol. Chem.
, vol.57
, pp. 463-470
-
-
Pincus, J.B.1
Kramer, B.2
-
171
-
-
84964140212
-
Physiological aspects of the penetration of drugs into the cerebrospinal fluid
-
Davson, H. & Smith, H. V. Physiological aspects of the penetration of drugs into the cerebrospinal fluid. Proc. R. Soc. Med. 50, 963-966 (1957).
-
(1957)
Proc. R. Soc. Med.
, vol.50
, pp. 963-966
-
-
Davson, H.1
Smith, H.V.2
-
172
-
-
33645184413
-
Drugs in the brain
-
Roth, L. J. & Barlow, C. F. Drugs in the brain. Science 134, 22-31 (1961).
-
(1961)
Science
, vol.134
, pp. 22-31
-
-
Roth, L.J.1
Barlow, C.F.2
-
173
-
-
0014109002
-
Fine structural localization of a blood-brain barrier to endogenous peroxidase
-
Reese, T. S. & Karnovsky, M. J. Fine structural localization of a blood-brain barrier to endogenous peroxidase. J. Cell Biol. 34, 207-217 (1967).
-
(1967)
J. Cell Biol.
, vol.34
, pp. 207-217
-
-
Reese, T.S.1
Karnovsky, M.J.2
-
174
-
-
70350718157
-
Cutting edge: Natalizumab blocks adhesion but not initial contact of human T cells to the blood-brain barrier in vivo in an animal model of multiple sclerosis
-
Coisne, C., Mao, W. & Engelhardt, B. Cutting edge: Natalizumab blocks adhesion but not initial contact of human T cells to the blood-brain barrier in vivo in an animal model of multiple sclerosis. J. Immunol. 182, 5909-5913 (2009).
-
(2009)
J. Immunol.
, vol.182
, pp. 5909-5913
-
-
Coisne, C.1
Mao, W.2
Engelhardt, B.3
|