Stroke upregulates TNFα transport across the blood-brain barrier

Experimental Neurology

Volumn 198, Issue 1, 2006, Pages 222-233

  Pan, Weihong ^a   Ding, Yuemin ^a   Yu, Yongmei ^a   Ohtaki, Hirokazu ^b   Nakamachi, Tomoya ^b   Kastin, Abba J ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

^b SHOWA UNIVERSITY   (Japan)

Author keywords

Blood brain barrier; Cerebral ischemia; Neuroplasticity; Stroke; TNF ; Transport

Indexed keywords

ALBUMIN; IODINE 125; IODINE 131; MESSENGER RNA; TUMOR NECROSIS FACTOR ALPHA; AAO1 PROTEIN, ARABIDOPSIS; ALDEHYDE OXIDASE; ARABIDOPSIS PROTEIN; DIAGNOSTIC AGENT; IODINE; TETRAZOLIUM; TRIPHENYLTETRAZOLIUM; TUMOR NECROSIS FACTOR RECEPTOR 1; TUMOR NECROSIS FACTOR RECEPTOR 2;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN INFARCTION; BRAIN PERFUSION; BRAIN REGION; BRAIN SIZE; CONTROLLED STUDY; HEMISPHERE; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOUSE; NERVE CELL PLASTICITY; NEUROLOGIC DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TRANSPORT; REPERFUSION INJURY; STROKE; UPREGULATION; ANIMAL; C57BL MOUSE; CEREBROVASCULAR ACCIDENT; COMPARATIVE STUDY; DISEASE MODEL; GENE EXPRESSION; GENETICS; METABOLISM; METHODOLOGY; MOTOR ACTIVITY; NEUROLOGIC EXAMINATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOMOTOR PERFORMANCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; TRANSPORT AT THE CELLULAR LEVEL;

ALDEHYDE OXIDASE; ANIMALS; ARABIDOPSIS PROTEINS; BIOLOGICAL TRANSPORT; BLOOD-BRAIN BARRIER; CEREBRAL INFARCTION; CEREBROVASCULAR ACCIDENT; DISEASE MODELS, ANIMAL; GENE EXPRESSION; IODINE ISOTOPES; MALE; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; NEUROLOGIC EXAMINATION; PSYCHOMOTOR PERFORMANCE; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE I; RECEPTORS, TUMOR NECROSIS FACTOR, TYPE II; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRAZOLIUM SALTS; TIME FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 32644440951     PISSN: 00144886     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.expneurol.2005.11.020     Document Type: Article

References (34)

1. T.J. Abbruscato, and T.P. Davis Protein expression of brain endothelial cell E-cadherin after hypoxia/aglycemia: influence of astrocyte contact Brain Res. 842 1999 277 286
2. F.C. Barone, B. Arvin, R.F. White, A. Miller, C.L. Webb, R.N. Willette, P.G. Lysko, and G.Z. Feuerstein Tumor necrosis factor-a. A mediator of focal ischemic brain injury Stroke 28 1997 1233 1244
3. A.L. Betz, R.F. Keep, M.E. Beer, and X.D. Ren Blood-brain-barrier permeability and brain concentration of sodium, potassium, and chloride during focal ischemia J. Cereb. Blood Flow Metab. 14 1994 29 37
4. G.I. Botchkina, M.E.I. Meistrell, I.L. Botchkina, and K.J. Tracey Expression of TNF and TNF receptors (p55 and p75) in the rat brain after focal cerebral ischemia Mol. Med. 3 1997 765 781
5. A.J. Bruce, W. Boling, M.S. Kindy, J. Peschon, P.J. Kraemer, M.K. Carpenter, F.W. Holtsberg, and M.P. Mattson Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors Nat. Med. 2 1996 788 794
6. J. Castillo, M.A. Moro, M. Blanco, R. Leira, J. Serena, I. Lizasoain, and A. Davalos The release of tumor necrosis factor-alpha is associated with ischemic tolerance in human stroke Ann. Neurol. 54 2003 811 819
7. Y. Ding, A.J. Kastin, and W. Pan Neural plasticity after spinal cord injury Curr. Pharm. Des. 11 2005 1441 1450
8. D.S. Gary, A.J. Bruce-Keller, M.S. Kindy, and M.P. Mattson Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor J. Cereb. Blood Flow Metab. 18 1998 1283 1287
9. I. Ginis, U. Schweizer, M. Brenner, J. Liu, N. Azzam, M. Spatz, and J.M. Hallenbeck TNF-alpha pretreatment prevents subsequent activation of cultured brain cells with TNF-alpha and hypoxia via ceramide Am. J. Physiol. 276 1999 C1171 C1183
10. I. Ginis, J.M. Hallenbeck, J. Liu, M. Spatz, R. Jaiswal, and E. Shohami Tumor necrosis factor and reactive oxygen species cooperative cytotoxicity is mediated via inhibition of NF-kappa B Mol. Med. 6 2000 1028 1041
11. G.A. Grant, N.J. Abbott, and D. Janigro Understanding the physiology of the blood-brain barrier: in vitro models News Physiol. Sci. 13 1998 287 293
12. E.G. Gutierrez, W.A. Banks, and A.J. Kastin Murine tumor necrosis factor alpha is transported from blood to brain in the mouse J. Neuroimmunol. 47 1993 169 176
13. J.M. Hallenbeck The many faces of tumor necrosis factor in stroke Nat. Med. 8 2002 1363 1368
14. K. Hattori, H. Lee, P.D. Hurn, B.J. Crain, R.J. Traystman, and A.C. Devries Cognitive deficits after focal cerebral ischemia in mice Stroke 31 2000 1939 1944
15. D. Intiso, M.M. Zarrelli, G. Lagioia, F. Di Rienzo, C.C. De Ambrosio, P. Simone, P. Tonali, and R.P. Cioffi Tumor necrosis factor alpha serum levels and inflammatory response in acute ischemic stroke patients Neurol. Sci. 24 2004 390 396
16. A. Kastrup, T. Engelhorn, C. Beaulieu, A. de Crespigny, and M.E. Moseley Dynamics of cerebral injury, perfusion, and blood-brain barrier changes after temporary and permanent middle cerebral artery occlusion in the rat J. Neurol. Sci. 166 1999 91 99
17. T. Liu, R.K. Clark, P.C. McDonnell, P.R. Young, R.F. White, F.C. Barone, and G.Z. Feuerstein Tumor necrosis factor-alpha expression in ischemic neurons Stroke 25 1994 1481 1488
18. J. Liu, I. Ginis, M. Spatz, and J.M. Hallenbeck Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-a and ceramide Am. J. Physiol. 278 2000 C144 C153
19. S. Maguire, R. Strittmatter, S. Chandra, and F.C. Barone Stroke-prone rats exhibit prolonged behavioral deficits without increased brain injury: an indication of disrupted post-stroke brain recovery of function Neurosci. Lett. 354 2004 229 233
20. H. Nawashiro, D. Martin, and J.M. Hallenbeck Inhibition of tumor necrosis factor and amelioration of brain infarction in mice J. Cereb. Blood Flow Metab. 17 1997 229 232
21. H. Nawashiro, K. Tasaki, C.A. Ruetzler, and J.M. Hallenbeck TNF-a pretreatment induces protective effects against focal cerebral ischemia in mice J. Cereb. Blood Flow Metab. 17 1997 483 490
22. B. Osburg, C. Peiser, D. Dömling, L. Schomburg, Y.T. Ko, K. Viogt, and U. Bickel Effect of endotoxin on expression of TNF receptors and transport of TNF-a at the blood-brain barrier of the rat Am. J. Physiol. 283 2002 E899 E908
23. W. Pan, and A.J. Kastin TNFa transport across the blood-brain barrier is abolished in receptor knockout mice Exp. Neurol. 174 2002 193 200
24. W. Pan, W.A. Banks, M.K. Kennedy, E.G. Gutierrez, and A.J. Kastin Differential permeability of the BBB in acute EAE: enhanced transport of TNF-a Am. J. Physiol. 271 1996 E636 E642
25. W. Pan, W.A. Banks, and A.J. Kastin BBB permeability to ebiratide and TNF in acute spinal cord injury Exp. Neurol. 146 1997 367 373
26. W. Pan, W.A. Banks, and A.J. Kastin Permeability of the blood-brain and blood-spinal cord barriers to interferons J. Neuroimmunol. 76 1997 105 111
27. W. Pan, J.E. Zadina, R.E. Harlan, J.T. Weber, W.A. Banks, and A.J. Kastin Tumor necrosis factor a: a neuromodulator in the CNS Neurosci. Biobehav. Rev. 21 1997 603 613
28. W. Pan, A.J. Kastin, R.L. Bell, and R.D. Olson Upregulation of tumor necrosis factor a transport across the blood-brain barrier after acute compressive spinal cord injury J. Neurosci. 19 1999 3649 3655
29. W. Pan, A.J. Kastin, R.N. McLay, T. Rigai, and C.G. Pick Increased hippocampal uptake of TNFa and behavioral changes in mice Exp. Brain Res. 149 2003 195 199
30. G.A. Rosenberg, E.Y. Estrada, and J.E. Dencoff Matrix metalloproteinases and TIMPs are associated with blood-brain barrier opening after reperfusion in rat brain Stroke 29 1998 2189 2195
31. A. Somogyvari-Vigh, W. Pan, D. Reglodi, A.J. Kastin, and A. Arimura Effect of middle cerebral artery occlusion on the passage of pituitary adenylate cyclase activating polypeptide across the blood-brain barrier in the rat Regul. Pept. 28 2000 89 95
32. Z.H. Wu, F.M. Hofman, and B.V. Zlokovic A simple method for isolation and characterization of mouse brain microvascular endothelial cells J. Neurosci. Methods 130 2003 53 63
33. L. Yin, H. Ohtaki, T. Nakamachi, Y. Kudo, R. Makino, and S. Shioda Delayed expressed TNFR1 co-localize with ICAM-1 in astrocyte in mice brain after transient focal ischemia Neurosci. Lett. 370 2004 30 35
34. J. Zaremba, and J. Losy Early TNF-alpha levels correlate with ischaemic stroke severity Acta Neurol. Scand. 104 2001 288 295