Soluble interleukin-6 receptor induces motor stereotypies and co-localizes with gp130 in regions linked to cortico-striato-thalamo-cortical circuits

PLoS ONE

Volumn 7, Issue 7, 2012, Pages

  Patel, Ankur ^a   Zhu, Youhua ^a   Kuzhikandathil, Eldo V ^a   Banks, William A ^b   Siegel, Allan ^a   Zalcman, Steven S ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN GP 130; INTERLEUKIN 6 RECEPTOR; RECOMBINANT PROTEIN; SOLUBLE INTERLEUKIN 6 RECEPTOR; UNCLASSIFIED DRUG; VANOXERINE;

ANATOMICAL VARIATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; CAUDATE NUCLEUS; CONTROLLED STUDY; CORPUS STRIATUM; DRUG TARGETING; ELECTROENCEPHALOGRAM; ENZYME ACTIVITY; MALE; MOTOR ACTIVITY; MOTOR CORTEX; MOUSE; NONHUMAN; NUCLEUS ACCUMBENS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PUTAMEN; SENSORIMOTOR CORTEX; SIGNAL TRANSDUCTION; STEREOTYPY; STRESS; SUBSTANTIA NIGRA; THALAMUS; VENTRAL TEGMENTUM;

ANIMALS; BEHAVIOR, ANIMAL; CEREBRAL CORTEX; CYTOKINE RECEPTOR GP130; HUMANS; INJECTIONS, SUBCUTANEOUS; MALE; MICE; MICE, INBRED BALB C; MOTOR ACTIVITY; NEOSTRIATUM; NERVE NET; PIPERAZINES; PROTEIN TRANSPORT; RECEPTORS, INTERLEUKIN-6; SOLUBILITY; STAINING AND LABELING; THALAMUS;

MUS;

EID: 84864231131     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0041623     Document Type: Article

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