Proteomic identification of less oxidized brain proteins in aged senescence-accelerated mice following administration of antisense oligonucleotide directed at the Aβ region of amyloid precursor protein

Molecular Brain Research

Volumn 138, Issue 1, 2005, Pages 8-16

  Poon, H Fai ^a   Farr, Susan A ^b,c   Banks, William A ^b,c   Pierce, William M ^d   Klein, Jon B ^e   Morley, John E ^b,c   Butterfield, D Allan ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c SAINT LOUIS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF LOUISVILLE SCHOOL OF MEDICINE   (United States)

^e University of Louisville School of Medicine   (United States)

Author keywords

Alzheimer's disease; Amyloid beta peptide; Amyloid precursor protein; Antisense oligonucleotide; Oxidative stress; Proteomic identification; SAMP8

Indexed keywords

ADENOSINE TRIPHOSPHATASE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; ANTISENSE OLIGODEOXYNUCLEOTIDE; BRAIN PROTEIN; FRUCTOSE BISPHOSPHATE ALDOLASE; KHELLIN; PEROXIREDOXIN; PROFILIN;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; ENDOSOME; INTERNALIZATION; LEARNING; LIPID PEROXIDATION; MEMORY CONSOLIDATION; MOUSE; MOUSE STRAIN; NONHUMAN; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STRUCTURE; SENESCENCE; SPECIES COMPARISON; STRUCTURAL PROTEOMICS; STRUCTURE ANALYSIS;

ACETALDEHYDE; AGING; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BLOTTING, WESTERN; BRAIN; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; MASS SPECTROMETRY; MICE; MICE, INBRED STRAINS; MODELS, BIOLOGICAL; OLIGONUCLEOTIDES, ANTISENSE; PROTEINS; PROTEOMICS;

EID: 22744455017     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molbrainres.2005.02.020     Document Type: Article

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