-
1
-
-
0028607336
-
Chemoresistance in the clinic: Overview 1994
-
Bates S. E., Regis J. I., Robey R. W., Zhan Z., Scala S., and Meadows B. J. (1994) Chemoresistance in the clinic: overview 1994. Bull. Cancer 9, 55s-61s.
-
(1994)
Bull. Cancer
, vol.9
-
-
Bates, S.E.1
Regis, J.I.2
Robey, R.W.3
Zhan, Z.4
Scala, S.5
Meadows, B.J.6
-
2
-
-
0026514505
-
Vincristine in therapeutic dosage appears to increase blood-brain barrier permeability to colchicine in the anesthetised guinea pig
-
Begley D. J. and Evans J. E. (1992) Vincristine in therapeutic dosage appears to increase blood-brain barrier permeability to colchicine in the anesthetised guinea pig. J. Physiol. (Lond.) 446, 449.
-
(1992)
J. Physiol. (Lond.)
, vol.446
, pp. 449
-
-
Begley, D.J.1
Evans, J.E.2
-
3
-
-
0029822580
-
Functional expression of P-glycoprotein in an immortalised cell line of rat brain endothelial cells, RBE4
-
Begley D. J., Lechardeur D., Chen Z.-D., Rollinson C., Bardoul M., Roux F., Scherman D., and Abbott N. J. (1996) Functional expression of P-glycoprotein in an immortalised cell line of rat brain endothelial cells, RBE4. J. Neurochem. 67, 988-995.
-
(1996)
J. Neurochem.
, vol.67
, pp. 988-995
-
-
Begley, D.J.1
Lechardeur, D.2
Chen, Z.-D.3
Rollinson, C.4
Bardoul, M.5
Roux, F.6
Scherman, D.7
Abbott, N.J.8
-
5
-
-
0002542906
-
Blood-brain cerebrospinal fluid barriers
-
(Siegel G. J., Agranoff B. W., Albers R. W., and Molinoff P. B., eds), Raven Press, New York
-
Betz A. L., Goldstein G. W., and Katzman R. (1989) Blood-brain cerebrospinal fluid barriers, in Basic Neurochemistry: Molecular, Cellular, and Medical Aspects, 4th edit. (Siegel G. J., Agranoff B. W., Albers R. W., and Molinoff P. B., eds), pp. 591-606. Raven Press, New York.
-
(1989)
Basic Neurochemistry: Molecular, Cellular, and Medical Aspects, 4th Edit.
, pp. 591-606
-
-
Betz, A.L.1
Goldstein, G.W.2
Katzman, R.3
-
6
-
-
0020522339
-
Transport of alpha-aminoisobutyric acid across brain capillary and cellular membranes
-
Blasberg R. G., Fenstermacher J. D., and Patlak C. S. (1983) Transport of alpha-aminoisobutyric acid across brain capillary and cellular membranes. J. Cereb. Blood Flow Metab. 3, 8-31.
-
(1983)
J. Cereb. Blood Flow Metab.
, vol.3
, pp. 8-31
-
-
Blasberg, R.G.1
Fenstermacher, J.D.2
Patlak, C.S.3
-
7
-
-
0000712439
-
Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites
-
Cordon-Cardo C., O'Brien J. P., Casals D., Rittman-Grauer L., Biedler J. L., Melamed M. R., and Bertino J. R. (1989) Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites. Proc. Natl. Acad. Sci. USA 86, 695-698.
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 695-698
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Casals, D.3
Rittman-Grauer, L.4
Biedler, J.L.5
Melamed, M.R.6
Bertino, J.R.7
-
8
-
-
0025071180
-
Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues
-
Cordon-Cardo C., O'Brien J. P., Boccia J., Casals D., Bertino J. R., and Melamed M. R. (1990) Expression of the multidrug resistance gene product (P-glycoprotein) in human normal and tumor tissues. J. Histochem. Cytochem. 38, 1277-1287.
-
(1990)
J. Histochem. Cytochem.
, vol.38
, pp. 1277-1287
-
-
Cordon-Cardo, C.1
O'Brien, J.P.2
Boccia, J.3
Casals, D.4
Bertino, J.R.5
Melamed, M.R.6
-
9
-
-
0028157006
-
Renal secretion of vinblastine, vincristine and colchicine in vivo
-
De Lannoy I. A. M., Mandin R. S., and Silverman M. (1994) Renal secretion of vinblastine, vincristine and colchicine in vivo. J. Pharmacol. Exp. Ther. 263, 388-395.
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.263
, pp. 388-395
-
-
De Lannoy, I.A.M.1
Mandin, R.S.2
Silverman, M.3
-
10
-
-
0025007511
-
Pharmacology of drugs that alter multidrug resistance in cancer
-
Ford J. M. and Hait W. N. (1990) Pharmacology of drugs that alter multidrug resistance in cancer. Pharmacol. Rev. 47, 155-199.
-
(1990)
Pharmacol. Rev.
, vol.47
, pp. 155-199
-
-
Ford, J.M.1
Hait, W.N.2
-
11
-
-
0000185678
-
SDZ PSC-833, a non-immunosuppressive cyclosporin analog, is a very potent multidrug-resistance modifier
-
Gaveriaux C., Boesch D., and Jachez B. (1991) SDZ PSC-833, a non-immunosuppressive cyclosporin analog, is a very potent multidrug-resistance modifier. J. Cell. Pharmacol. 2, 225-234.
-
(1991)
J. Cell. Pharmacol.
, vol.2
, pp. 225-234
-
-
Gaveriaux, C.1
Boesch, D.2
Jachez, B.3
-
12
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman M. M. and Pastan I. (1993) Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 62, 385-427.
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
13
-
-
1842275495
-
Effects of vincristine on brain uptake of P-glycoprotein substrates in anaesthetized adult rats
-
Habgood M. D., Begley D. J., and Abbott N. J. (1996) Effects of vincristine on brain uptake of P-glycoprotein substrates in anaesthetized adult rats. J. Physiol. (Lond.) 491, 37P-38P.
-
(1996)
J. Physiol. (Lond.)
, vol.491
-
-
Habgood, M.D.1
Begley, D.J.2
Abbott, N.J.3
-
14
-
-
0027092617
-
Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells
-
Hegmann E. J., Bauer H. C., and Kerbel R. S. (1992) Expression and functional activity of P-glycoprotein in cultured cerebral capillary endothelial cells. Cancer Res. 52, 6969-6975.
-
(1992)
Cancer Res.
, vol.52
, pp. 6969-6975
-
-
Hegmann, E.J.1
Bauer, H.C.2
Kerbel, R.S.3
-
15
-
-
0028079955
-
Reversion of P-glycoprotein mediated multi-drug resistance to vincristine and adriamycin by PSC-833, a cyclosporin derivative in human neuroblastoma cell lines
-
Helson C., Zahn Z., and Helson L. (1994) Reversion of P-glycoprotein mediated multi-drug resistance to vincristine and adriamycin by PSC-833, a cyclosporin derivative in human neuroblastoma cell lines. Int. J. Oncol. 5, 1037-1042.
-
(1994)
Int. J. Oncol.
, vol.5
, pp. 1037-1042
-
-
Helson, C.1
Zahn, Z.2
Helson, L.3
-
16
-
-
0027184425
-
High levels of P-glycoprotein detected in isolated brain capillaries
-
Jetté L., Têtu B., and Béliveau R. (1993) High levels of P-glycoprotein detected in isolated brain capillaries. Biochim. Biophys. Acta 1150, 147-154.
-
(1993)
Biochim. Biophys. Acta
, vol.1150
, pp. 147-154
-
-
Jetté, L.1
Têtu, B.2
Béliveau, R.3
-
17
-
-
0026539377
-
SDZ PSC-833, a nonimmunosuppressive cyclosporin: Its potency in overcoming P-glycoprotein mediated multidrug resistance of murine leukemia
-
Keller R. P., Altermatt H. J., and Nooter K. (1992) SDZ PSC-833, a nonimmunosuppressive cyclosporin: its potency in overcoming P-glycoprotein mediated multidrug resistance of murine leukemia. Int. J. Cancer 50, 593-597.
-
(1992)
Int. J. Cancer
, vol.50
, pp. 593-597
-
-
Keller, R.P.1
Altermatt, H.J.2
Nooter, K.3
-
19
-
-
0019124032
-
Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability
-
Levin V. A. (1980) Relationship of octanol/water partition coefficient and molecular weight to rat brain capillary permeability. J. Med Chem. 23, 682-684.
-
(1980)
J. Med Chem.
, vol.23
, pp. 682-684
-
-
Levin, V.A.1
-
21
-
-
0018237164
-
Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat
-
Ohno K., Pettigrew K. D., and Rapoport S. I. (1978) Lower limits of cerebrovascular permeability to nonelectrolytes in the conscious rat. Am. J. Physiol. 235, H299-H307.
-
(1978)
Am. J. Physiol.
, vol.235
-
-
Ohno, K.1
Pettigrew, K.D.2
Rapoport, S.I.3
-
22
-
-
0016354690
-
Lipid solubility and drug penetration of the blood-brain barrier
-
Oldendorf W. H. (1974) Lipid solubility and drug penetration of the blood-brain barrier. Proc. Soc. Exp. Biol Med. 147, 813-816.
-
(1974)
Proc. Soc. Exp. Biol Med.
, vol.147
, pp. 813-816
-
-
Oldendorf, W.H.1
-
24
-
-
0026834343
-
Pharmacokinetics of colchicine: A review of experimental and clinical data
-
Sabouraud A., Rochdi M., Urtizberea M., Christen M. O., Achtert G., and Scherrmann J. M. (1992) Pharmacokinetics of colchicine: a review of experimental and clinical data. Z. Gastroenterol. 30, 35-39.
-
(1992)
Z. Gastroenterol.
, vol.30
, pp. 35-39
-
-
Sabouraud, A.1
Rochdi, M.2
Urtizberea, M.3
Christen, M.O.4
Achtert, G.5
Scherrmann, J.M.6
-
25
-
-
0028229150
-
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
-
Schinkel A. H., Smit J. J. M., van Tellingen O., Beijnen J. H., Wagenaar E., van Deemter L., Mol C. A. A. M., van der Valk M. A., Robanus-Maandag E. C., te Riele H. P., Berns A. J. M., and Borst P. (1994) Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs. Cell 77, 491-502.
-
(1994)
Cell
, vol.77
, pp. 491-502
-
-
Schinkel, A.H.1
Smit, J.J.M.2
Van Tellingen, O.3
Beijnen, J.H.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.A.M.7
Van Der Valk, M.A.8
Robanus-Maandag, E.C.9
Te Riele, H.P.10
Berns, A.J.M.11
Borst, P.12
-
26
-
-
0027970462
-
Functional studies of P-glycoprotein in inside-out plasma membrane vesicles derived from murine erythroleukemia cells overexpressing MDR 3
-
Schlemmer S. R. and Sirotnak F. M. (1994) Functional studies of P-glycoprotein in inside-out plasma membrane vesicles derived from murine erythroleukemia cells overexpressing MDR 3. J. Biol. Chem. 269, 31059-31066.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 31059-31066
-
-
Schlemmer, S.R.1
Sirotnak, F.M.2
-
27
-
-
0021920344
-
Regional cerebrovascular transport of leucine as measured by the in situ brain perfusion method
-
Smith Q. R., Takasato Y., Sweeney D. J., and Rapoport S. I. (1985) Regional cerebrovascular transport of leucine as measured by the in situ brain perfusion method. J. Cereb. Blood Flow Metab. 5, 300-311.
-
(1985)
J. Cereb. Blood Flow Metab.
, vol.5
, pp. 300-311
-
-
Smith, Q.R.1
Takasato, Y.2
Sweeney, D.J.3
Rapoport, S.I.4
-
28
-
-
0000821015
-
Influence of cerebral blood flow on tryptophan uptake into brain
-
(Lubec G. and Rosenthal G. A., eds), ESCOM Science Publishers, Amsterdam
-
Smith Q. R., Fukui S., Robinson P., and Rapoport S. I. (1990) Influence of cerebral blood flow on tryptophan uptake into brain, in Amino Acids: Chemistry, Biology and Medicine (Lubec G. and Rosenthal G. A., eds), pp. 364-369. ESCOM Science Publishers, Amsterdam.
-
(1990)
Amino Acids: Chemistry, Biology and Medicine
, pp. 364-369
-
-
Smith, Q.R.1
Fukui, S.2
Robinson, P.3
Rapoport, S.I.4
-
29
-
-
0026636982
-
Effect of cyclosporine on colchicine secretion by the kidney multidrug transporter studied in vivo
-
Speeg V. K., Maldonado A. L., Liaci J., and Muirhead D. (1992a) Effect of cyclosporine on colchicine secretion by the kidney multidrug transporter studied in vivo. J. Pharmacol. Exp. Ther. 261, 50-55.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.261
, pp. 50-55
-
-
Speeg, V.K.1
Maldonado, A.L.2
Liaci, J.3
Muirhead, D.4
-
30
-
-
0026603791
-
Effect of cyclosporine on colchicine secretion by a liver canalicular transporter studied in vivo
-
Speeg V. K., Maldonado A. L., Liaci J., and Muirhead D. (1992b) Effect of cyclosporine on colchicine secretion by a liver canalicular transporter studied in vivo. Hepatology 15, 899-903.
-
(1992)
Hepatology
, vol.15
, pp. 899-903
-
-
Speeg, V.K.1
Maldonado, A.L.2
Liaci, J.3
Muirhead, D.4
-
31
-
-
0000545811
-
An in situ brain perfusion technique to study cerebrovascular transport in the rat
-
Takasato Y., Rapoport S. I., and Smith Q. R. (1984) An in situ brain perfusion technique to study cerebrovascular transport in the rat. Am. J. Physiol. 247, H484-H493.
-
(1984)
Am. J. Physiol.
, vol.247
-
-
Takasato, Y.1
Rapoport, S.I.2
Smith, Q.R.3
-
32
-
-
0026669192
-
Functional involvement of P-glycoprotein in blood-brain barrier
-
Tatsuta T., Naito M., Oh-hara T., Sugawara I., and Tsuruo T. (1992) Functional involvement of P-glycoprotein in blood-brain barrier. J. Biol. Chem. 267, 20383-20391.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 20383-20391
-
-
Tatsuta, T.1
Naito, M.2
Oh-hara, T.3
Sugawara, I.4
Tsuruo, T.5
-
33
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F., Tsuruo T., Hamada H., Gottesman M. M., Pastan I., and Willingham M. C. (1987) Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc. Natl. Acad. Sci. USA 84, 7735-7738.
-
(1987)
Proc. Natl. Acad. Sci. USA
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
34
-
-
0024576304
-
Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: Evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein
-
Thiebaut F., Tsuruo T., Hamada H., Gottesman M. M., Pastan I., and Willingham M. C. (1989) Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein. J. Histochem. Cytochem. 37, 159-164.
-
(1989)
J. Histochem. Cytochem.
, vol.37
, pp. 159-164
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
35
-
-
0026760889
-
P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells
-
Tsuji A., Terasaki T., Takabatake Y., Tenda Y., Tamai I., Yamashima T., Moritani S., Tsuruo T., and Yamashita J. (1992) P-glycoprotein as the drug efflux pump in primary cultured bovine brain capillary endothelial cells. Life Sci. 51, 1427-1437.
-
(1992)
Life Sci.
, vol.51
, pp. 1427-1437
-
-
Tsuji, A.1
Terasaki, T.2
Takabatake, Y.3
Tenda, Y.4
Tamai, I.5
Yamashima, T.6
Moritani, S.7
Tsuruo, T.8
Yamashita, J.9
-
36
-
-
0019430432
-
Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil
-
Tsuruo T., Iida H., Tsukagoshi S., and Sakurai Y. (1981) Overcoming of vincristine resistance in P388 leukemia in vivo and in vitro through enhanced cytotoxicity of vincristine and vinblastine by verapamil. Cancer Res. 41, 1967-1972.
-
(1981)
Cancer Res.
, vol.41
, pp. 1967-1972
-
-
Tsuruo, T.1
Iida, H.2
Tsukagoshi, S.3
Sakurai, Y.4
|