ENOS gene deletion restores blood-brain barrier integrity and attenuates neurodegeneration in the thiamine-deficient mouse brain

Journal of Neurochemistry

Volumn 111, Issue 2, 2009, Pages 452-459

  Beauchesne, Élizabeth ^a   Desjardins, Paul ^a   Hazell, Alan S ^a   Butterworth, Roger F ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Blood brain barrier; Endothelial nitric oxide synthase; Neuronal cell death; Thiamine deficiency; Wernicke's encephalopathy

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GELATINASE B; HEME OXYGENASE 1; IMMUNOGLOBULIN G; S NITROSOCYSTEINE; THIAMINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN DISEASE; CONTROLLED STUDY; ENDOTHELIUM CELL; GENE DELETION; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE DEGENERATION; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; THIAMINE DEFICIENCY;

ANIMALS; ANTIMETABOLITES; BLOOD-BRAIN BARRIER; DISEASE MODELS, ANIMAL; FRONTAL LOBE; IMMUNOGLOBULIN G; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE DEGENERATION; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PYRITHIAMINE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; THALAMIC NUCLEI; THIAMINE DEFICIENCY;

MUS;

EID: 70349319841     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2009.06338.x     Document Type: Article

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