Identification of genotoxic compounds using isogenic DNA repair deficient DT40 cell lines on a quantitative high throughput screening platform

Mutagenesis

Volumn 31, Issue 1, 2016, Pages 69-81

  Nishihara, Kana ^a,b   Huang, Ruili ^b   Zhao, Jinghua ^b   Shahane, Sampada A ^b   Witt, Kristine L ^c   Smith Roe, Stephanie L ^c   Tice, Raymond R ^c   Takeda, Shunichi ^a   Xia, Menghang ^b  

^a KYOTO UNIVERSITY   (Japan)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXIRANEMETHANAMINE; AD 67; ADENOSINE TRIPHOSPHATE; DOXORUBICIN; KU ANTIGEN; MELPHALAN; RAD54 PROTEIN; REV3 PROTEIN; TETRAPHENYLOLETHANE GLYCIDYL; TOXIC SUBSTANCE; UNCLASSIFIED DRUG; CELL NUCLEUS ANTIGEN; DNA BINDING PROTEIN; DNA DIRECTED DNA POLYMERASE; MUTAGENIC AGENT;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL CLONE; CELL VIABILITY ASSAY; CYTOTOXICITY; DNA DAMAGE; DNA SYNTHESIS; DOUBLE STRANDED DNA BREAK; GENOTOXICITY; HIGH THROUGHPUT SCREENING; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; ANIMAL; B LYMPHOCYTE; CELL LINE; CHICKEN; DNA REPAIR; DRUG EFFECTS; GENETICS; MUTAGEN TESTING; MUTATION; PROCEDURES;

ANIMALS; ANTIGENS, NUCLEAR; B-LYMPHOCYTES; CELL LINE; CHICKENS; DNA BREAKS, DOUBLE-STRANDED; DNA REPAIR; DNA-BINDING PROTEINS; DNA-DIRECTED DNA POLYMERASE; HIGH-THROUGHPUT SCREENING ASSAYS; KU AUTOANTIGEN; MUTAGENICITY TESTS; MUTAGENS; MUTATION;

EID: 84954487603     PISSN: 02678357     EISSN: 14643804     Source Type: Journal    
DOI: 10.1093/mutage/gev055     Document Type: Article

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