A novel approach using DNA-repair-deficient chicken DT40 cell lines for screening and characterizing the genotoxicity of environmental contaminants

Environmental Health Perspectives

Volumn 117, Issue 11, 2009, Pages 1737-1744

  Ji, Kyunghee ^a,b   Kogame, Toshiaki ^b   Choi, Kyungho ^a   Wang, Xin ^b   Lee, Jinyoung ^a,b   Taniguchi, Yoshihito ^b   Takeda, Shunichi ^b  

^a Seoul National University   (South Korea)

^b KYOTO UNIVERSITY   (Japan)

Author keywords

Alternative test methods development; Arsenic; DNA repair; Genotoxicity; High throughput testing; UV radiation

Indexed keywords

ADENOSINE TRIPHOSPHATE; ARSENITE SODIUM; ENVIRONMENTAL MUTAGEN;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE; BIOASSAY; CELL CYCLE; CELL LINE; CELL PROLIFERATION; CELL VIABILITY; CHICKEN; CHROMOSOME BREAKAGE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; GAMMA RADIATION; GENOTOXICITY; NONHUMAN; PRIORITY JOURNAL; RELIABILITY; SCREENING; SENSITIVITY ANALYSIS; ULTRAVIOLET RADIATION; VALIDITY;

ANIMALS; ARSENITES; B-LYMPHOCYTES; BIOLOGICAL ASSAY; CELL LINE; CELL PROLIFERATION; CHICKENS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; GAMMA RAYS; HUMANS; MUTAGENICITY TESTS; MUTAGENS; REPRODUCIBILITY OF RESULTS; SODIUM COMPOUNDS; TIME FACTORS; ULTRAVIOLET RAYS;

BACTERIA (MICROORGANISMS); MAMMALIA;

EID: 74949085703     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.0900842     Document Type: Article

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