메뉴 건너뛰기




Volumn 1845, Issue 1, 2014, Pages 84-89

Doxorubicin, DNA torsion, and chromatin dynamics

Author keywords

Anthracycline; Cancer; Chemotherapy; Chromatin dynamics; DNA torsion; Doxorubicin

Indexed keywords

CERAMIDE; DNA TOPOISOMERASE (ATP HYDROLYSING); DOXORUBICIN; VALPROIC ACID; VOSAROXIN;

EID: 84891592249     PISSN: 0304419X     EISSN: 18792561     Source Type: Journal    
DOI: 10.1016/j.bbcan.2013.12.002     Document Type: Review
Times cited : (565)

References (79)
  • 2
    • 0014473575 scopus 로고
    • Adriamycin (NSC-123,127): a new antibiotic with antitumor activity
    • Di Marco A., Gaetani M., Scarpinato B. Adriamycin (NSC-123,127): a new antibiotic with antitumor activity. Cancer Chemother. Rep. 1969, 53:33-37.
    • (1969) Cancer Chemother. Rep. , vol.53 , pp. 33-37
    • Di Marco, A.1    Gaetani, M.2    Scarpinato, B.3
  • 4
    • 0033006172 scopus 로고    scopus 로고
    • A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin
    • Gewirtz D.A. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin. Biochem. Pharmacol. 1999, 57:727-741.
    • (1999) Biochem. Pharmacol. , vol.57 , pp. 727-741
    • Gewirtz, D.A.1
  • 5
    • 2642566088 scopus 로고    scopus 로고
    • Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity
    • Minotti G., Menna P., Salvatorelli E., Cairo G., Gianni L. Anthracyclines: molecular advances and pharmacologic developments in antitumor activity and cardiotoxicity. Pharmacol. Rev. 2004, 56:185-229.
    • (2004) Pharmacol. Rev. , vol.56 , pp. 185-229
    • Minotti, G.1    Menna, P.2    Salvatorelli, E.3    Cairo, G.4    Gianni, L.5
  • 6
    • 0035819885 scopus 로고    scopus 로고
    • Targeting ceramide metabolism-a strategy for overcoming drug resistance
    • Senchenkov A., Litvak D.A., Cabot M.C. Targeting ceramide metabolism-a strategy for overcoming drug resistance. J. Natl. Cancer Inst. 2001, 93:347-357.
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 347-357
    • Senchenkov, A.1    Litvak, D.A.2    Cabot, M.C.3
  • 7
    • 84861095603 scopus 로고    scopus 로고
    • Topological domains in mammalian genomes identified by analysis of chromatin interactions
    • Dixon J.R., Selvaraj S., Yue F., Kim A., Li Y., Shen Y., Hu M., Liu J.S., Ren B. Topological domains in mammalian genomes identified by analysis of chromatin interactions. Nature 2012, 485:376-380.
    • (2012) Nature , vol.485 , pp. 376-380
    • Dixon, J.R.1    Selvaraj, S.2    Yue, F.3    Kim, A.4    Li, Y.5    Shen, Y.6    Hu, M.7    Liu, J.S.8    Ren, B.9
  • 11
    • 84877585708 scopus 로고    scopus 로고
    • Doxorubicin enhances nucleosome turnover around promoters
    • Yang F., Kemp C.J., Henikoff S. Doxorubicin enhances nucleosome turnover around promoters. Curr. Biol. 2013, 23:782-787.
    • (2013) Curr. Biol. , vol.23 , pp. 782-787
    • Yang, F.1    Kemp, C.J.2    Henikoff, S.3
  • 12
    • 77954187741 scopus 로고    scopus 로고
    • DNA topoisomerases and their poisoning by anticancer and antibacterial drugs
    • Pommier Y., Leo E., Zhang H., Marchand C. DNA topoisomerases and their poisoning by anticancer and antibacterial drugs. Chem. Biol. 2010, 17:421-433.
    • (2010) Chem. Biol. , vol.17 , pp. 421-433
    • Pommier, Y.1    Leo, E.2    Zhang, H.3    Marchand, C.4
  • 13
    • 9444229370 scopus 로고    scopus 로고
    • Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell line
    • Carpenter A.J., Porter A.C. Construction, characterization, and complementation of a conditional-lethal DNA topoisomerase IIalpha mutant human cell line. Mol. Biol. Cell 2004, 15:5700-5711.
    • (2004) Mol. Biol. Cell , vol.15 , pp. 5700-5711
    • Carpenter, A.J.1    Porter, A.C.2
  • 15
    • 64649090292 scopus 로고    scopus 로고
    • Targeting DNA topoisomerase II in cancer chemotherapy
    • Nitiss J.L. Targeting DNA topoisomerase II in cancer chemotherapy. Nat. Rev. Cancer 2009, 9:338-350.
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 338-350
    • Nitiss, J.L.1
  • 17
    • 33646394582 scopus 로고    scopus 로고
    • Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death
    • Swift L.P., Rephaeli A., Nudelman A., Phillips D.R., Cutts S.M. Doxorubicin-DNA adducts induce a non-topoisomerase II-mediated form of cell death. Cancer Res. 2006, 66:4863-4871.
    • (2006) Cancer Res. , vol.66 , pp. 4863-4871
    • Swift, L.P.1    Rephaeli, A.2    Nudelman, A.3    Phillips, D.R.4    Cutts, S.M.5
  • 18
    • 0027065109 scopus 로고
    • Mode of action of topoisomerase II-targeting agents at a specific DNA sequence, uncoupling the DNA binding, cleavage and religation events
    • Sorensen B.S., Sinding J., Andersen A.H., Alsner J., Jensen P.B., Westergaard O. Mode of action of topoisomerase II-targeting agents at a specific DNA sequence, uncoupling the DNA binding, cleavage and religation events. J. Mol. Biol. 1992, 228:778-786.
    • (1992) J. Mol. Biol. , vol.228 , pp. 778-786
    • Sorensen, B.S.1    Sinding, J.2    Andersen, A.H.3    Alsner, J.4    Jensen, P.B.5    Westergaard, O.6
  • 19
    • 84869209094 scopus 로고    scopus 로고
    • Identification of the molecular basis of doxorubicin-induced cardiotoxicity
    • Zhang S., Liu X., Bawa-Khalfe T., Lu L.S., Lyu Y.L., Liu L.F., Yeh E.T. Identification of the molecular basis of doxorubicin-induced cardiotoxicity. Nat. Med. 2012, 18:1639-1642.
    • (2012) Nat. Med. , vol.18 , pp. 1639-1642
    • Zhang, S.1    Liu, X.2    Bawa-Khalfe, T.3    Lu, L.S.4    Lyu, Y.L.5    Liu, L.F.6    Yeh, E.T.7
  • 20
    • 84885024579 scopus 로고    scopus 로고
    • Catalytic inhibitors of topoisomerase II differently modulate the toxicity of anthracyclines in cardiac and cancer cells
    • Vavrova A., Jansova H., Mackova E., Machacek M., Haskova P., Tichotova L., Sterba M., Simunek T. Catalytic inhibitors of topoisomerase II differently modulate the toxicity of anthracyclines in cardiac and cancer cells. PLoS One 2013, 8:e76676.
    • (2013) PLoS One , vol.8
    • Vavrova, A.1    Jansova, H.2    Mackova, E.3    Machacek, M.4    Haskova, P.5    Tichotova, L.6    Sterba, M.7    Simunek, T.8
  • 21
    • 0025298798 scopus 로고
    • Preferential binding of daunomycin to 5'ATCG and 5'ATGC sequences revealed by footprinting titration experiments
    • Chaires J.B., Herrera J.E., Waring M.J. Preferential binding of daunomycin to 5'ATCG and 5'ATGC sequences revealed by footprinting titration experiments. Biochemistry 1990, 29:6145-6153.
    • (1990) Biochemistry , vol.29 , pp. 6145-6153
    • Chaires, J.B.1    Herrera, J.E.2    Waring, M.J.3
  • 23
    • 0022650763 scopus 로고
    • A theoretical investigation on the sequence selective binding of adriamycin to double-stranded polynucleotides
    • Chen K.S., Gresh N., Pullman B. A theoretical investigation on the sequence selective binding of adriamycin to double-stranded polynucleotides. Nucleic Acids Res. 1986, 14:2251-2267.
    • (1986) Nucleic Acids Res. , vol.14 , pp. 2251-2267
    • Chen, K.S.1    Gresh, N.2    Pullman, B.3
  • 25
    • 52649163984 scopus 로고    scopus 로고
    • Detection of adriamycin-DNA adducts by accelerator mass spectrometry at clinically relevant adriamycin concentrations
    • Coldwell K.E., Cutts S.M., Ognibene T.J., Henderson P.T., Phillips D.R. Detection of adriamycin-DNA adducts by accelerator mass spectrometry at clinically relevant adriamycin concentrations. Nucleic Acids Res. 2008, 36:e100.
    • (2008) Nucleic Acids Res. , vol.36
    • Coldwell, K.E.1    Cutts, S.M.2    Ognibene, T.J.3    Henderson, P.T.4    Phillips, D.R.5
  • 26
    • 0029840013 scopus 로고    scopus 로고
    • Alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin
    • Taatjes D.J., Gaudiano G., Resing K., Koch T.H. Alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin. J. Med. Chem. 1996, 39:4135-4138.
    • (1996) J. Med. Chem. , vol.39 , pp. 4135-4138
    • Taatjes, D.J.1    Gaudiano, G.2    Resing, K.3    Koch, T.H.4
  • 27
    • 0030991136 scopus 로고    scopus 로고
    • Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin
    • Taatjes D.J., Gaudiano G., Resing K., Koch T.H. Redox pathway leading to the alkylation of DNA by the anthracycline, antitumor drugs adriamycin and daunomycin. J. Med. Chem. 1997, 40:1276-1286.
    • (1997) J. Med. Chem. , vol.40 , pp. 1276-1286
    • Taatjes, D.J.1    Gaudiano, G.2    Resing, K.3    Koch, T.H.4
  • 28
    • 0035393735 scopus 로고    scopus 로고
    • Formaldehyde in human cancer cells: detection by preconcentration-chemical ionization mass spectrometry
    • Kato S., Burke P.J., Koch T.H., Bierbaum V.M. Formaldehyde in human cancer cells: detection by preconcentration-chemical ionization mass spectrometry. Anal. Chem. 2001, 73:2992-2997.
    • (2001) Anal. Chem. , vol.73 , pp. 2992-2997
    • Kato, S.1    Burke, P.J.2    Koch, T.H.3    Bierbaum, V.M.4
  • 29
    • 0034091435 scopus 로고    scopus 로고
    • Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs
    • Kato S., Burke P.J., Fenick D.J., Taatjes D.J., Bierbaum V.M., Koch T.H. Mass spectrometric measurement of formaldehyde generated in breast cancer cells upon treatment with anthracycline antitumor drugs. Chem. Res. Toxicol. 2000, 13:509-516.
    • (2000) Chem. Res. Toxicol. , vol.13 , pp. 509-516
    • Kato, S.1    Burke, P.J.2    Fenick, D.J.3    Taatjes, D.J.4    Bierbaum, V.M.5    Koch, T.H.6
  • 30
    • 0035890824 scopus 로고    scopus 로고
    • Molecular basis for the synergistic interaction of adriamycin with the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate (AN-9)
    • Cutts S.M., Rephaeli A., Nudelman A., Hmelnitsky I., Phillips D.R. Molecular basis for the synergistic interaction of adriamycin with the formaldehyde-releasing prodrug pivaloyloxymethyl butyrate (AN-9). Cancer Res. 2001, 61:8194-8202.
    • (2001) Cancer Res. , vol.61 , pp. 8194-8202
    • Cutts, S.M.1    Rephaeli, A.2    Nudelman, A.3    Hmelnitsky, I.4    Phillips, D.R.5
  • 34
    • 0019457695 scopus 로고
    • Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 reductase produces DNA cleavage in a reaction mediated by molecular oxygen
    • Berlin V., Haseltine W.A. Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 reductase produces DNA cleavage in a reaction mediated by molecular oxygen. J. Biol. Chem. 1981, 256:4747-4756.
    • (1981) J. Biol. Chem. , vol.256 , pp. 4747-4756
    • Berlin, V.1    Haseltine, W.A.2
  • 35
    • 0031714464 scopus 로고    scopus 로고
    • The role of iron in doxorubicin-induced cardiomyopathy
    • Myers C. The role of iron in doxorubicin-induced cardiomyopathy. Semin. Oncol. 1998, 25:10-14.
    • (1998) Semin. Oncol. , vol.25 , pp. 10-14
    • Myers, C.1
  • 36
    • 0035353186 scopus 로고    scopus 로고
    • Oxidative DNA base modifications in peripheral blood mononuclear cells of patients treated with high-dose infusional doxorubicin
    • Doroshow J.H., Synold T.W., Somlo G., Akman S.A., Gajewski E. Oxidative DNA base modifications in peripheral blood mononuclear cells of patients treated with high-dose infusional doxorubicin. Blood 2001, 97:2839-2845.
    • (2001) Blood , vol.97 , pp. 2839-2845
    • Doroshow, J.H.1    Synold, T.W.2    Somlo, G.3    Akman, S.A.4    Gajewski, E.5
  • 38
    • 34247859168 scopus 로고    scopus 로고
    • Oxidative DNA base damage in MCF-10A breast epithelial cells at clinically achievable concentrations of doxorubicin
    • Gajewski E., Gaur S., Akman S.A., Matsumoto L., van Balgooy J.N., Doroshow J.H. Oxidative DNA base damage in MCF-10A breast epithelial cells at clinically achievable concentrations of doxorubicin. Biochem. Pharmacol. 2007, 73:1947-1956.
    • (2007) Biochem. Pharmacol. , vol.73 , pp. 1947-1956
    • Gajewski, E.1    Gaur, S.2    Akman, S.A.3    Matsumoto, L.4    van Balgooy, J.N.5    Doroshow, J.H.6
  • 39
    • 0035831158 scopus 로고    scopus 로고
    • Doxorubicin and mechanical performance of cardiac trabeculae after acute and chronic treatment: a review
    • De Beer E.L., Bottone A.E., Voest E.E. Doxorubicin and mechanical performance of cardiac trabeculae after acute and chronic treatment: a review. Eur. J. Pharmacol. 2001, 415:1-11.
    • (2001) Eur. J. Pharmacol. , vol.415 , pp. 1-11
    • De Beer, E.L.1    Bottone, A.E.2    Voest, E.E.3
  • 40
    • 84856112404 scopus 로고    scopus 로고
    • Doxorubicin increases oxidative metabolism in HL-1 cardiomyocytes as shown by 13C metabolic flux analysis
    • Strigun A., Wahrheit J., Niklas J., Heinzle E., Noor F. Doxorubicin increases oxidative metabolism in HL-1 cardiomyocytes as shown by 13C metabolic flux analysis. Toxicol. Sci. 2012, 125:595-606.
    • (2012) Toxicol. Sci. , vol.125 , pp. 595-606
    • Strigun, A.1    Wahrheit, J.2    Niklas, J.3    Heinzle, E.4    Noor, F.5
  • 41
    • 80054787805 scopus 로고    scopus 로고
    • Targeting histone demethylases: a new avenue for the fight against cancer
    • Rotili D., Mai A. Targeting histone demethylases: a new avenue for the fight against cancer. Genes Cancer 2011, 2:663-679.
    • (2011) Genes Cancer , vol.2 , pp. 663-679
    • Rotili, D.1    Mai, A.2
  • 42
    • 72249115358 scopus 로고    scopus 로고
    • Niacin status impacts chromatin structure
    • Kirkland J.B. Niacin status impacts chromatin structure. J. Nutr. 2009, 139:2397-2401.
    • (2009) J. Nutr. , vol.139 , pp. 2397-2401
    • Kirkland, J.B.1
  • 45
    • 0033565728 scopus 로고    scopus 로고
    • Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells
    • Lucci A., Han T.Y., Liu Y.Y., Giuliano A.E., Cabot M.C. Multidrug resistance modulators and doxorubicin synergize to elevate ceramide levels and elicit apoptosis in drug-resistant cancer cells. Cancer 1999, 86:300-311.
    • (1999) Cancer , vol.86 , pp. 300-311
    • Lucci, A.1    Han, T.Y.2    Liu, Y.Y.3    Giuliano, A.E.4    Cabot, M.C.5
  • 47
    • 84871946952 scopus 로고    scopus 로고
    • Epigenetic silencing of antiviral genes renders clones of Huh-7 cells permissive for hepatitis C virus replication
    • Chen Q., Denard B., Huang H., Ye J. Epigenetic silencing of antiviral genes renders clones of Huh-7 cells permissive for hepatitis C virus replication. J. Virol. 2013, 87:659-665.
    • (2013) J. Virol. , vol.87 , pp. 659-665
    • Chen, Q.1    Denard, B.2    Huang, H.3    Ye, J.4
  • 48
    • 78650303774 scopus 로고    scopus 로고
    • Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition
    • Ji C., Yang B., Yang Y.L., He S.H., Miao D.S., He L., Bi Z.G. Exogenous cell-permeable C6 ceramide sensitizes multiple cancer cell lines to Doxorubicin-induced apoptosis by promoting AMPK activation and mTORC1 inhibition. Oncogene 2010, 29:6557-6568.
    • (2010) Oncogene , vol.29 , pp. 6557-6568
    • Ji, C.1    Yang, B.2    Yang, Y.L.3    He, S.H.4    Miao, D.S.5    He, L.6    Bi, Z.G.7
  • 49
    • 4344559711 scopus 로고    scopus 로고
    • Ceramide reduction and transcriptional up-regulation of glucosylceramide synthase through doxorubicin-activated Sp1 in drug-resistant HL-60/ADR cells
    • Uchida Y., Itoh M., Taguchi Y., Yamaoka S., Umehara H., Ichikawa S., Hirabayashi Y., Holleran W.M., Okazaki T. Ceramide reduction and transcriptional up-regulation of glucosylceramide synthase through doxorubicin-activated Sp1 in drug-resistant HL-60/ADR cells. Cancer Res. 2004, 64:6271-6279.
    • (2004) Cancer Res. , vol.64 , pp. 6271-6279
    • Uchida, Y.1    Itoh, M.2    Taguchi, Y.3    Yamaoka, S.4    Umehara, H.5    Ichikawa, S.6    Hirabayashi, Y.7    Holleran, W.M.8    Okazaki, T.9
  • 51
    • 0035079539 scopus 로고    scopus 로고
    • Ceramide glycosylation potentiates cellular multidrug resistance
    • Liu Y.Y., Han T.Y., Giuliano A.E., Cabot M.C. Ceramide glycosylation potentiates cellular multidrug resistance. FASEB J. 2001, 15:719-730.
    • (2001) FASEB J. , vol.15 , pp. 719-730
    • Liu, Y.Y.1    Han, T.Y.2    Giuliano, A.E.3    Cabot, M.C.4
  • 52
    • 79952767541 scopus 로고    scopus 로고
    • Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells
    • Liu Y.Y., Patwardhan G.A., Bhinge K., Gupta V., Gu X., Jazwinski S.M. Suppression of glucosylceramide synthase restores p53-dependent apoptosis in mutant p53 cancer cells. Cancer Res. 2011, 71:2276-2285.
    • (2011) Cancer Res. , vol.71 , pp. 2276-2285
    • Liu, Y.Y.1    Patwardhan, G.A.2    Bhinge, K.3    Gupta, V.4    Gu, X.5    Jazwinski, S.M.6
  • 53
    • 84881522110 scopus 로고    scopus 로고
    • Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1
    • Denard B., Lee C., Ye J. Doxorubicin blocks proliferation of cancer cells through proteolytic activation of CREB3L1. Elife 2012, 1:e00090.
    • (2012) Elife , vol.1
    • Denard, B.1    Lee, C.2    Ye, J.3
  • 54
    • 0017134585 scopus 로고
    • Mechanisms of chromosome banding. IX. Are variations in DNA base composition adequate to account for quinacrine, Hoechst 33258 and daunomycin banding?
    • Comings D.E., Drets M.E. Mechanisms of chromosome banding. IX. Are variations in DNA base composition adequate to account for quinacrine, Hoechst 33258 and daunomycin banding?. Chromosoma 1976, 56:199-211.
    • (1976) Chromosoma , vol.56 , pp. 199-211
    • Comings, D.E.1    Drets, M.E.2
  • 55
    • 0023433855 scopus 로고
    • Supercoiling of the DNA template during transcription
    • Liu L.F., Wang J.C. Supercoiling of the DNA template during transcription. Proc. Natl. Acad. Sci. U. S. A. 1987, 84:7024-7027.
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 7024-7027
    • Liu, L.F.1    Wang, J.C.2
  • 56
    • 0024279845 scopus 로고
    • Transcription generates positively and negatively supercoiled domains in the template
    • Wu H.Y., Shyy S.H., Wang J.C., Liu L.F. Transcription generates positively and negatively supercoiled domains in the template. Cell 1988, 53:433-440.
    • (1988) Cell , vol.53 , pp. 433-440
    • Wu, H.Y.1    Shyy, S.H.2    Wang, J.C.3    Liu, L.F.4
  • 57
    • 0034704235 scopus 로고    scopus 로고
    • Generation of superhelical torsion by ATP-dependent chromatin remodeling activities
    • Havas K., Flaus A., Phelan M., Kingston R., Wade P.A., Lilley D.M., Owen-Hughes T. Generation of superhelical torsion by ATP-dependent chromatin remodeling activities. Cell 2000, 103:1133-1142.
    • (2000) Cell , vol.103 , pp. 1133-1142
    • Havas, K.1    Flaus, A.2    Phelan, M.3    Kingston, R.4    Wade, P.A.5    Lilley, D.M.6    Owen-Hughes, T.7
  • 59
    • 0026452036 scopus 로고
    • Positive supercoiling of DNA greatly diminishes mRNA synthesis in yeast
    • Gartenberg M.R., Wang J.C. Positive supercoiling of DNA greatly diminishes mRNA synthesis in yeast. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:11461-11465.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 11461-11465
    • Gartenberg, M.R.1    Wang, J.C.2
  • 60
    • 84870524315 scopus 로고    scopus 로고
    • Topoisomerase II is required for the production of long Pol II gene transcripts in yeast
    • Joshi R.S., Pina B., Roca J. Topoisomerase II is required for the production of long Pol II gene transcripts in yeast. Nucleic Acids Res. 2012, 40:7907-7915.
    • (2012) Nucleic Acids Res. , vol.40 , pp. 7907-7915
    • Joshi, R.S.1    Pina, B.2    Roca, J.3
  • 62
    • 73449148377 scopus 로고    scopus 로고
    • Nucleosome assembly depends on the torsion in the DNA molecule: a magnetic tweezers study
    • Gupta P., Zlatanova J., Tomschik M. Nucleosome assembly depends on the torsion in the DNA molecule: a magnetic tweezers study. Biophys. J. 2009, 97:3150-3157.
    • (2009) Biophys. J. , vol.97 , pp. 3150-3157
    • Gupta, P.1    Zlatanova, J.2    Tomschik, M.3
  • 63
    • 15944408542 scopus 로고    scopus 로고
    • Atomic force microscopy demonstrates a critical role of DNA superhelicity in nucleosome dynamics
    • Hizume K., Yoshimura S.H., Takeyasu K. Atomic force microscopy demonstrates a critical role of DNA superhelicity in nucleosome dynamics. Cell Biochem. Biophys. 2004, 40:249-261.
    • (2004) Cell Biochem. Biophys. , vol.40 , pp. 249-261
    • Hizume, K.1    Yoshimura, S.H.2    Takeyasu, K.3
  • 64
    • 0025965065 scopus 로고
    • Formation of nucleosomes on positively supercoiled DNA
    • Clark D.J., Felsenfeld G. Formation of nucleosomes on positively supercoiled DNA. EMBO J. 1991, 10:387-395.
    • (1991) EMBO J. , vol.10 , pp. 387-395
    • Clark, D.J.1    Felsenfeld, G.2
  • 65
    • 84865461059 scopus 로고    scopus 로고
    • Measuring genome-wide nucleosome turnover using CATCH-IT
    • Teves S.S., Deal R.B., Henikoff S. Measuring genome-wide nucleosome turnover using CATCH-IT. Methods Enzymol. 2012, 513:169-184.
    • (2012) Methods Enzymol. , vol.513 , pp. 169-184
    • Teves, S.S.1    Deal, R.B.2    Henikoff, S.3
  • 66
    • 77952996319 scopus 로고    scopus 로고
    • Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones
    • Deal R.B., Henikoff J.G., Henikoff S. Genome-wide kinetics of nucleosome turnover determined by metabolic labeling of histones. Science 2010, 328:1161-1164.
    • (2010) Science , vol.328 , pp. 1161-1164
    • Deal, R.B.1    Henikoff, J.G.2    Henikoff, S.3
  • 69
    • 0026036393 scopus 로고
    • Transcription-induced nucleosome 'splitting': an underlying structure for DNase I sensitive chromatin
    • Lee M.S., Garrard W.T. Transcription-induced nucleosome 'splitting': an underlying structure for DNase I sensitive chromatin. EMBO J. 1991, 10:607-615.
    • (1991) EMBO J. , vol.10 , pp. 607-615
    • Lee, M.S.1    Garrard, W.T.2
  • 70
    • 84893786534 scopus 로고    scopus 로고
    • Transcription-generated torsional stress destabilizes nucleosomes
    • Teves S.S., Henikoff S. Transcription-generated torsional stress destabilizes nucleosomes. Nat. Struct. Mol. Biol. 2013.
    • (2013) Nat. Struct. Mol. Biol.
    • Teves, S.S.1    Henikoff, S.2
  • 71
    • 67650725820 scopus 로고    scopus 로고
    • The biology of chromatin remodeling complexes
    • Clapier C.R., Cairns B.R. The biology of chromatin remodeling complexes. Annu. Rev. Biochem. 2009, 78:273-304.
    • (2009) Annu. Rev. Biochem. , vol.78 , pp. 273-304
    • Clapier, C.R.1    Cairns, B.R.2
  • 72
    • 2542622944 scopus 로고    scopus 로고
    • Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila somatic mutation and recombination test
    • Lehmann M., Vilar Kde S., Franco A., Reguly M.L., Rodrigues de Andrade H.H. Activity of topoisomerase inhibitors daunorubicin, idarubicin, and aclarubicin in the Drosophila somatic mutation and recombination test. Environ. Mol. Mutagen. 2004, 43:250-257.
    • (2004) Environ. Mol. Mutagen. , vol.43 , pp. 250-257
    • Lehmann, M.1    Vilar Kde, S.2    Franco, A.3    Reguly, M.L.4    Rodrigues de Andrade, H.H.5
  • 74
    • 30344443991 scopus 로고    scopus 로고
    • In vivo synergy between topoisomerase II and histone deacetylase inhibitors: predictive correlates
    • Marchion D.C., Bicaku E., Daud A.I., Sullivan D.M., Munster P.N. In vivo synergy between topoisomerase II and histone deacetylase inhibitors: predictive correlates. Mol. Cancer Ther. 2005, 4:1993-2000.
    • (2005) Mol. Cancer Ther. , vol.4 , pp. 1993-2000
    • Marchion, D.C.1    Bicaku, E.2    Daud, A.I.3    Sullivan, D.M.4    Munster, P.N.5
  • 75
    • 33751505528 scopus 로고    scopus 로고
    • Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells
    • Catalano M.G., Fortunati N., Pugliese M., Poli R., Bosco O., Mastrocola R., Aragno M., Boccuzzi G. Valproic acid, a histone deacetylase inhibitor, enhances sensitivity to doxorubicin in anaplastic thyroid cancer cells. J. Endocrinol. 2006, 191:465-472.
    • (2006) J. Endocrinol. , vol.191 , pp. 465-472
    • Catalano, M.G.1    Fortunati, N.2    Pugliese, M.3    Poli, R.4    Bosco, O.5    Mastrocola, R.6    Aragno, M.7    Boccuzzi, G.8
  • 76
    • 18144373452 scopus 로고    scopus 로고
    • Valproic acid alters chromatin structure by regulation of chromatin modulation proteins
    • Marchion D.C., Bicaku E., Daud A.I., Sullivan D.M., Munster P.N. Valproic acid alters chromatin structure by regulation of chromatin modulation proteins. Cancer Res. 2005, 65:3815-3822.
    • (2005) Cancer Res. , vol.65 , pp. 3815-3822
    • Marchion, D.C.1    Bicaku, E.2    Daud, A.I.3    Sullivan, D.M.4    Munster, P.N.5
  • 79
    • 2942616456 scopus 로고    scopus 로고
    • Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways
    • Wang S., Konorev E.A., Kotamraju S., Joseph J., Kalivendi S., Kalyanaraman B. Doxorubicin induces apoptosis in normal and tumor cells via distinctly different mechanisms. intermediacy of H(2)O(2)- and p53-dependent pathways. J. Biol. Chem. 2004, 279:25535-25543.
    • (2004) J. Biol. Chem. , vol.279 , pp. 25535-25543
    • Wang, S.1    Konorev, E.A.2    Kotamraju, S.3    Joseph, J.4    Kalivendi, S.5    Kalyanaraman, B.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.