Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes

International Journal of Oncology

Volumn 39, Issue 1, 2011, Pages 263-270

  Suzuki, Norihiko ^a   Emura, Tomohiro ^a   Fukushima, Masakazu ^a  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

5 fluoro 2 deoxyuridine; 5 fluorouracil; 5 trifluoromethyl 2 deoxyuridine; DNA repair; DNA replication; TFT; Trifluorothymidine

Indexed keywords

ADENINE; CELL EXTRACT; DNA GLYCOSYLTRANSFERASE; FLOXURIDINE; FLUOROURACIL; GUANINE; METHYL CPG BINDING PROTEIN; METHYL CPG BINDING PROTEIN 4; SMALL INTERFERING RNA; THYMIDINE TRIPHOSPHATE; THYMINE DNA GLYCOSYLASE; TRIFLURIDINE; UNCLASSIFIED DRUG; URACIL DNA GLYCOSIDASE;

ARTICLE; CELL FRACTIONATION; CELL STRAIN; CONCENTRATION RESPONSE; CYTOTOXICITY; DNA CLEAVAGE; DNA REPAIR; DNA REPLICATION; DNA STRAND; DRUG DNA BINDING; DRUG MECHANISM; ENZYME ASSAY; GEL FILTRATION; HUMAN; HUMAN CELL; IC 50; PRIORITY JOURNAL;

ANTIMETABOLITES; DNA GLYCOSYLASES; DNA POLYMERASE I; DNA REPAIR; DNA REPLICATION; ENDODEOXYRIBONUCLEASES; ENZYME ACTIVATION; FLUOROURACIL; GENE KNOCKDOWN TECHNIQUES; HELA CELLS; HUMANS; RNA, SMALL INTERFERING; TRIFLURIDINE;

EID: 79955981402     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.1003     Document Type: Article

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