-
3
-
-
39349118236
-
Transforming environmental health protection
-
DOI 10.1126/science.1154619
-
F.S. Collins Toxicology. Transforming environmental health protection Science 319 2008 906 907 (Pubitemid 351263750)
-
(2008)
Science
, vol.319
, Issue.5865
, pp. 906-907
-
-
Collins, F.S.1
Gray, G.M.2
Bucher, J.R.3
-
4
-
-
77953994301
-
Toxicity testing in the 21st century: A vision and a strategy
-
D. Krewski Toxicity testing in the 21st century: a vision and a strategy J. Toxicol. Environ. Health B: Crit. Rev. 13 2010 51 138
-
(2010)
J. Toxicol. Environ. Health B: Crit. Rev.
, vol.13
, pp. 51-138
-
-
Krewski, D.1
-
5
-
-
84879599189
-
Improving the human hazard characterization of chemicals: A Tox21 update
-
doi 10.1289/ehp.1205784, in press
-
Tice, R.R. et al. (2013) Improving the human hazard characterization of chemicals: a Tox21 update. Environ Health Perspect, doi 10.1289/ehp.1205784, in press.
-
(2013)
Environ Health Perspect
-
-
Tice, R.R.1
-
6
-
-
78649630186
-
The future of toxicity testing: A focus on in vitro methods using a quantitative high throughput screening platform
-
S.J. Shukla The future of toxicity testing: a focus on in vitro methods using a quantitative high throughput screening platform Drug Discov. Today 15 2010 997 1007
-
(2010)
Drug Discov. Today
, vol.15
, pp. 997-1007
-
-
Shukla, S.J.1
-
8
-
-
62749084516
-
Toxicity testing in the 21st century: Implications for human health risk assessment
-
discussion 492-487
-
R.J. Kavlock Toxicity testing in the 21st century: implications for human health risk assessment Risk Anal. 29 2009 485 487 discussion 492-487
-
(2009)
Risk Anal.
, vol.29
, pp. 485-487
-
-
Kavlock, R.J.1
-
9
-
-
84877297399
-
Perspectives on validation of high-throughput assays supporting 21st century toxicity testing
-
R. Judson Perspectives on validation of high-throughput assays supporting 21st century toxicity testing ALTEX 30 2013 51 56
-
(2013)
ALTEX
, vol.30
, pp. 51-56
-
-
Judson, R.1
-
10
-
-
0033003760
-
A simple statistical parameter for use in evaluation and validation of high throughput screening assays
-
J.H. Zhang A simple statistical parameter for use in evaluation and validation of high throughput screening assays J. Biomol. Screen. 4 1999 67 73
-
(1999)
J. Biomol. Screen.
, vol.4
, pp. 67-73
-
-
Zhang, J.H.1
-
11
-
-
54949108677
-
PubChem: Integrated platform of small molecules and biological activities
-
American Chemical Society
-
E. Bolton PubChem: integrated platform of small molecules and biological activities Annual Reports in Computational Chemistry Vol. 4 2008 American Chemical Society
-
(2008)
Annual Reports in Computational Chemistry
, vol.4
-
-
Bolton, E.1
-
12
-
-
79955428497
-
The NCGC pharmaceutical collection: A comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics
-
R. Huang The NCGC pharmaceutical collection: a comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics Sci. Transl. Med. 3 2011 80ps16
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Huang, R.1
-
13
-
-
40149087853
-
Compound Management for Quantitative High-Throughput Screening
-
DOI 10.1016/j.jala.2007.12.004, PII S1535553507003541
-
A. Yasgar Compound management for quantitative high-throughput screening JALA 13 2008 79 89 (Pubitemid 351325745)
-
(2008)
JALA - Journal of the Association for Laboratory Automation
, vol.13
, Issue.2
, pp. 79-89
-
-
Yasgar, A.1
Shinn, P.2
Jadhav, A.3
Auld, D.4
Michael, S.5
Zheng, W.6
Austin, C.P.7
Inglese, J.8
Simeonov, A.9
-
14
-
-
57049118570
-
A robotic platform for quantitative high-throughput screening
-
S. Michael A robotic platform for quantitative high-throughput screening Assay Drug Dev. Technol. 6 2008 637 657
-
(2008)
Assay Drug Dev. Technol.
, vol.6
, pp. 637-657
-
-
Michael, S.1
-
15
-
-
79961042769
-
Chemical genomics profiling of environmental chemical modulation of human nuclear receptors
-
R. Huang Chemical genomics profiling of environmental chemical modulation of human nuclear receptors Environ. Health Perspect. 119 2011 1142 1148
-
(2011)
Environ. Health Perspect.
, vol.119
, pp. 1142-1148
-
-
Huang, R.1
-
16
-
-
85051691015
-
Enabling the large scale analysis of quantitative high throughput screening data
-
R. Seethala, L. Zhang, Taylor and Francis
-
N.T. Southall Enabling the large scale analysis of quantitative high throughput screening data R. Seethala, L. Zhang, Handbook of Drug Screening 2009 Taylor and Francis 442 463
-
(2009)
Handbook of Drug Screening
, pp. 442-463
-
-
Southall, N.T.1
-
17
-
-
0003043542
-
The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves
-
A.V. Hill The possible effects of the aggregation of the molecules of haemoglobin on its dissociation curves J. Physiol. (Lond.) 40 1910 4 7
-
(1910)
J. Physiol. (Lond.)
, vol.40
, pp. 4-7
-
-
Hill, A.V.1
-
18
-
-
78249280753
-
A grid algorithm for high throughput fitting of dose-response curve data
-
Y. Wang A grid algorithm for high throughput fitting of dose-response curve data Curr. Chem. Genom. 4 2011 57 66
-
(2011)
Curr. Chem. Genom.
, vol.4
, pp. 57-66
-
-
Wang, Y.1
-
19
-
-
33746789921
-
Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries
-
DOI 10.1073/pnas.0604348103
-
J. Inglese Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries Proc. Natl Acad. Sci. U. S. A. 103 2006 11473 11478 (Pubitemid 44182476)
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, Issue.31
, pp. 11473-11478
-
-
Inglese, J.1
Auld, D.S.2
Jadhav, A.3
Johnson, R.L.4
Simeonov, A.5
Yasgar, A.6
Zheng, W.7
Austin, C.P.8
-
20
-
-
80053516123
-
Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data
-
N.S. Sipes Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data Toxicol. Sci. 124 2011 109 127
-
(2011)
Toxicol. Sci.
, vol.124
, pp. 109-127
-
-
Sipes, N.S.1
-
21
-
-
80052549683
-
Predictive model of rat reproductive toxicity from ToxCast high throughput screening
-
M.T. Martin Predictive model of rat reproductive toxicity from ToxCast high throughput screening Biol. Reprod. 85 2011 327 339
-
(2011)
Biol. Reprod.
, vol.85
, pp. 327-339
-
-
Martin, M.T.1
-
22
-
-
77951675220
-
In vitro screening of environmental chemicals for targeted testing prioritization: The ToxCast project
-
R.S. Judson In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project Environ. Health Perspect. 118 2010 485 492
-
(2010)
Environ. Health Perspect.
, vol.118
, pp. 485-492
-
-
Judson, R.S.1
-
23
-
-
74949084682
-
Weighted feature significance: A simple, interpretable model of compound toxicity based on the statistical enrichment of structural features
-
R. Huang Weighted feature significance: a simple, interpretable model of compound toxicity based on the statistical enrichment of structural features Toxicol. Sci. 112 2009 385 393
-
(2009)
Toxicol. Sci.
, vol.112
, pp. 385-393
-
-
Huang, R.1
-
24
-
-
84862775836
-
Paradigm shift in toxicity testing and modeling
-
H. Sun Paradigm shift in toxicity testing and modeling AAPS J. 14 2012 473 480
-
(2012)
AAPS J.
, vol.14
, pp. 473-480
-
-
Sun, H.1
-
25
-
-
40849137783
-
Compound cytotoxicity profiling using quantitative high-throughput screening
-
DOI 10.1289/ehp.10727
-
M. Xia Compound cytotoxicity profiling using quantitative high-throughput screening Environ. Health Perspect. 116 2008 284 291 (Pubitemid 351395593)
-
(2008)
Environmental Health Perspectives
, vol.116
, Issue.3
, pp. 284-291
-
-
Xia, M.1
Huang, R.2
Witt, K.L.3
Southall, N.4
Fostel, J.5
Cho, M.-H.6
Jadhav, A.7
Smith, C.S.8
Inglese, J.9
Portier, C.J.10
Tice, R.R.11
Austin, C.P.12
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