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Volumn 157, Issue 1, 2016, Pages 176-194

Neurotensin is coexpressed, coreleased, and acts together with GLP-1 and PYY in enteroendocrine control of metabolism

Author keywords

[No Author keywords available]

Indexed keywords

GLUCAGON LIKE PEPTIDE 1; NEUROPEPTIDE; NEUROTENSIN; PEPTIDE YY; PERTUSSIS TOXIN; PROGLUCAGON; SOMATOSTATIN; BIOLOGICAL MARKER; BOMBESIN; G PROTEIN COUPLED RECEPTOR; GPCR41 PROTEIN, MOUSE; HYBRID PROTEIN; NEUROMEDIN C; PEPTIDE FRAGMENT; PHOTOPROTEIN; RED FLUORESCENT PROTEIN;

EID: 84954482475     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2015-1600     Document Type: Article
Times cited : (122)

References (94)
  • 2
    • 84878808238 scopus 로고    scopus 로고
    • Pharmacology, physiology, and mechanisms of incretin hormone action
    • Campbell JE, Drucker DJ. Pharmacology, physiology, and mechanisms of incretin hormone action. Cell Metab. 2013;17:819-837.
    • (2013) Cell Metab. , vol.17 , pp. 819-837
    • Campbell, J.E.1    Drucker, D.J.2
  • 3
  • 5
    • 66049102943 scopus 로고    scopus 로고
    • The control of food intake: Behavioral versus molecular perspectives
    • Woods SC. The control of food intake: behavioral versus molecular perspectives. Cell Metab. 2009;9:489-498.
    • (2009) Cell Metab. , vol.9 , pp. 489-498
    • Woods, S.C.1
  • 6
    • 84862207266 scopus 로고    scopus 로고
    • Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide
    • Astrup A, Carraro R, Finer N, et al. Safety, tolerability and sustained weight loss over 2 years with the once-daily human GLP-1 analog, liraglutide. Int J Obes (Lond). 2012;36:843-854.
    • (2012) Int J Obes (Lond) , vol.36 , pp. 843-854
    • Astrup, A.1    Carraro, R.2    Finer, N.3
  • 7
    • 84858006062 scopus 로고    scopus 로고
    • The role of GLP-1 mimetics and basal insulin analogues in type 2 diabetes mellitus: Guidance from studies of liraglutide
    • Barnett AH. The role of GLP-1 mimetics and basal insulin analogues in type 2 diabetes mellitus: guidance from studies of liraglutide. Diabetes Obes Metab. 2012;14:304-314.
    • (2012) Diabetes Obes Metab. , vol.14 , pp. 304-314
    • Barnett, A.H.1
  • 8
    • 84928032636 scopus 로고    scopus 로고
    • GLP-1 based therapeutics: Simultaneously combating T2DM and obesity
    • Heppner KM, Perez-Tilve D. GLP-1 based therapeutics: simultaneously combating T2DM and obesity. Front Neurosci. 2015;9:92.
    • (2015) Front Neurosci. , vol.9 , pp. 92
    • Heppner, K.M.1    Perez-Tilve, D.2
  • 9
    • 84929206792 scopus 로고    scopus 로고
    • Liraglutide and obesity: A review of the data so far
    • Ladenheim EE. Liraglutide and obesity: a review of the data so far. Drug Des Devel Ther. 2015;9:1867-1875.
    • (2015) Drug des Devel Ther. , vol.9 , pp. 1867-1875
    • Ladenheim, E.E.1
  • 11
    • 84914127466 scopus 로고    scopus 로고
    • The physiology underlying Roux-en-Y gastric bypass: A status report
    • Lutz TA, Bueter M. The physiology underlying Roux-en-Y gastric bypass: a status report. Am J Physiol Regul Integr Comp Physiol. 2014;307:R1275-R1291.
    • (2014) Am J Physiol Regul Integr Comp Physiol. , vol.307 , pp. R1275-R1291
    • Lutz, T.A.1    Bueter, M.2
  • 12
    • 84888199705 scopus 로고    scopus 로고
    • Enteroendocrine secretion of gut hormones in diabetes, obesity and after bariatric surgery
    • Holst JJ. Enteroendocrine secretion of gut hormones in diabetes, obesity and after bariatric surgery. Curr Opin Pharmacol. 2013;13:983-988.
    • (2013) Curr Opin Pharmacol. , vol.13 , pp. 983-988
    • Holst, J.J.1
  • 13
    • 84881353226 scopus 로고    scopus 로고
    • Gastrointestinal hormones and bariatric surgery-induced weight loss
    • Ionut V, Burch M, Youdim A, Bergman RN. Gastrointestinal hormones and bariatric surgery-induced weight loss. Obesity. 2013;21:1093-1103.
    • (2013) Obesity , vol.21 , pp. 1093-1103
    • Ionut, V.1    Burch, M.2    Youdim, A.3    Bergman, R.N.4
  • 14
    • 84910003335 scopus 로고    scopus 로고
    • Metabolic surgery: Action via hormonal milieu changes, changes in bile acids or gut microbiota? A summary of the literature
    • Sweeney TE, Morton JM. Metabolic surgery: action via hormonal milieu changes, changes in bile acids or gut microbiota? A summary of the literature. Best Pract Res Clin Gastroenterol. 2014;28:727-740.
    • (2014) Best Pract Res Clin Gastroenterol. , vol.28 , pp. 727-740
    • Sweeney, T.E.1    Morton, J.M.2
  • 15
    • 33646182727 scopus 로고    scopus 로고
    • Organizing cell renewal in the intestine: Stem cells, signals and combinatorial control
    • Crosnier C, Stamataki D, Lewis J. Organizing cell renewal in the intestine: stem cells, signals and combinatorial control. Nat Rev Genet. 2006;7:349-359.
    • (2006) Nat Rev Genet. , vol.7 , pp. 349-359
    • Crosnier, C.1    Stamataki, D.2    Lewis, J.3
  • 16
    • 49649125933 scopus 로고    scopus 로고
    • Targeted ablation of glucose-dependent insulinotropic polypeptideproducing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet
    • Althage MC, Ford EL, Wang S, Tso P, Polonsky KS, Wice BM. Targeted ablation of glucose-dependent insulinotropic polypeptideproducing cells in transgenic mice reduces obesity and insulin resistance induced by a high fat diet. J Biol Chem. 2008;283:18365-18376.
    • (2008) J Biol Chem. , vol.283 , pp. 18365-18376
    • Althage, M.C.1    Ford, E.L.2    Wang, S.3    Tso, P.4    Polonsky, K.S.5    Wice, B.M.6
  • 17
    • 0031722813 scopus 로고    scopus 로고
    • The new biology of gastrointestinal hormones
    • Rehfeld JF. The new biology of gastrointestinal hormones. Physiol Rev. 1998;78:1087-1108.
    • (1998) Physiol Rev. , vol.78 , pp. 1087-1108
    • Rehfeld, J.F.1
  • 18
    • 2342606044 scopus 로고    scopus 로고
    • The "normal" endocrine cell of the gut: Changing concepts and new evidences
    • Rindi G, Leiter AB, Kopin AS, Bordi C, Solcia E. The "normal" endocrine cell of the gut: changing concepts and new evidences. Ann NY Acad Sci. 2004;1014:1-12.
    • (2004) Ann NY Acad Sci. , vol.1014 , pp. 1-12
    • Rindi, G.1    Leiter, A.B.2    Kopin, A.S.3    Bordi, C.4    Solcia, E.5
  • 19
    • 79251564398 scopus 로고    scopus 로고
    • A stem cell marker-expressing subset of enteroendocrine cells resides at the crypt base in the small intestine
    • Sei Y, Lu X, Liou A, Zhao X, Wank SA. A stem cell marker-expressing subset of enteroendocrine cells resides at the crypt base in the small intestine. Am J Physiol Gastrointest Liver Physiol. 2011;300:G345-G356.
    • (2011) Am J Physiol Gastrointest Liver Physiol. , vol.300 , pp. G345-G356
    • Sei, Y.1    Lu, X.2    Liou, A.3    Zhao, X.4    Wank, S.A.5
  • 20
    • 0028025301 scopus 로고
    • Immunohistochemical studies indicate multiple enteroendocrine cell differentiation pathways in the mouse proximal small intestine
    • Aiken KD, Kisslinger JA, Roth KA. Immunohistochemical studies indicate multiple enteroendocrine cell differentiation pathways in the mouse proximal small intestine. Dev Dyn. 1994;201:63-70.
    • (1994) Dev Dyn. , vol.201 , pp. 63-70
    • Aiken, K.D.1    Kisslinger, J.A.2    Roth, K.A.3
  • 21
    • 0027070802 scopus 로고
    • Temporal differentiation and migration of substance P, serotonin, and secretin immunoreactive enteroendocrine cells in the mouse proximal small intestine
    • Aiken KD, Roth KA. Temporal differentiation and migration of substance P, serotonin, and secretin immunoreactive enteroendocrine cells in the mouse proximal small intestine. Dev Dyn. 1992;194:303-310.
    • (1992) Dev Dyn. , vol.194 , pp. 303-310
    • Aiken, K.D.1    Roth, K.A.2
  • 22
    • 84870225450 scopus 로고    scopus 로고
    • A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin
    • Egerod KL, Engelstoft MS, Grunddal KV, et al. A major lineage of enteroendocrine cells coexpress CCK, secretin, GIP, GLP-1, PYY, and neurotensin but not somatostatin. Endocrinology. 2012;153:5782-5795.
    • (2012) Endocrinology , vol.153 , pp. 5782-5795
    • Egerod, K.L.1    Engelstoft, M.S.2    Grunddal, K.V.3
  • 24
    • 84860536527 scopus 로고    scopus 로고
    • The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice
    • Beucher A, Gjernes E, Collin C, et al. The homeodomain-containing transcription factors Arx and Pax4 control enteroendocrine subtype specification in mice. PLoS One. 2012;7:e36449.
    • (2012) PLoS One , vol.7 , pp. e36449
    • Beucher, A.1    Gjernes, E.2    Collin, C.3
  • 25
    • 84862743498 scopus 로고    scopus 로고
    • Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry
    • Habib AM, Richards P, Cairns LS, et al. Overlap of endocrine hormone expression in the mouse intestine revealed by transcriptional profiling and flow cytometry. Endocrinology. 2012;153:3054-3065.
    • (2012) Endocrinology , vol.153 , pp. 3054-3065
    • Habib, A.M.1    Richards, P.2    Cairns, L.S.3
  • 26
    • 0015821329 scopus 로고
    • The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami
    • Caraway RE, Leeman SE. The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem. 1973;248:17138-17144.
    • (1973) J Biol Chem. , vol.248 , pp. 17138-17144
    • Caraway, R.E.1    Leeman, S.E.2
  • 27
    • 84877101527 scopus 로고    scopus 로고
    • Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA
    • Kempadoo KA, Tourino C, Cho SL, et al. Hypothalamic neurotensin projections promote reward by enhancing glutamate transmission in the VTA. J Neurosci. 2013;33:7618-7626.
    • (2013) J Neurosci. , vol.33 , pp. 7618-7626
    • Kempadoo, K.A.1    Tourino, C.2    Cho, S.L.3
  • 28
    • 80052707655 scopus 로고    scopus 로고
    • Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance
    • Leinninger GM, Opland DM, Jo YH, et al. Leptin action via neurotensin neurons controls orexin, the mesolimbic dopamine system and energy balance. Cell Metab. 2011;14:313-323.
    • (2011) Cell Metab. , vol.14 , pp. 313-323
    • Leinninger, G.M.1    Opland, D.M.2    Jo, Y.H.3
  • 29
    • 84889087755 scopus 로고    scopus 로고
    • Loss of neurotensin receptor-1 disrupts the control of the mesolimbic dopamine system by leptin and promotes hedonic feeding and obesity
    • Opland D, Sutton A, Woodworth H, et al. Loss of neurotensin receptor-1 disrupts the control of the mesolimbic dopamine system by leptin and promotes hedonic feeding and obesity. Mol Metab. 2013;2:423-434.
    • (2013) Mol Metab. , vol.2 , pp. 423-434
    • Opland, D.1    Sutton, A.2    Woodworth, H.3
  • 30
    • 0020333709 scopus 로고
    • Neurotensin: Discovery, isolation, characterization, synthesis and possible physiological roles
    • Leeman SE, Carraway RE. Neurotensin: discovery, isolation, characterization, synthesis and possible physiological roles. Ann NY Acad Sci. 1982;400:1-16.
    • (1982) Ann NY Acad Sci. , vol.400 , pp. 1-16
    • Leeman, S.E.1    Carraway, R.E.2
  • 31
    • 0019393620 scopus 로고
    • Pancreatic endocrine responses to exogenous neurotensin in the conscious calf
    • Blackburn AM, Bloom SR, Edwards AV. Pancreatic endocrine responses to exogenous neurotensin in the conscious calf. J Physiol. 1981;314:11-21.
    • (1981) J Physiol. , vol.314 , pp. 11-21
    • Blackburn, A.M.1    Bloom, S.R.2    Edwards, A.V.3
  • 32
    • 0019393838 scopus 로고
    • Pancreatic endocrine responses to physiological changes in plasma neurotensin concentration in the calf
    • Blackburn AM, Bloom SR, Edwards AV. Pancreatic endocrine responses to physiological changes in plasma neurotensin concentration in the calf. J Physiol. 1981;318:407-412.
    • (1981) J Physiol. , vol.318 , pp. 407-412
    • Blackburn, A.M.1    Bloom, S.R.2    Edwards, A.V.3
  • 33
    • 0018192270 scopus 로고
    • Effects of substance P and neurotensin infused intrapancreatically on glucagon and insulin secretion
    • Kaneto A, Kaneko T, Kajinuma H, Kosaka K. Effects of substance P and neurotensin infused intrapancreatically on glucagon and insulin secretion. Endocrinology. 1978;102:393-401.
    • (1978) Endocrinology , vol.102 , pp. 393-401
    • Kaneto, A.1    Kaneko, T.2    Kajinuma, H.3    Kosaka, K.4
  • 34
    • 51849099001 scopus 로고    scopus 로고
    • Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119
    • Semple G, Fioravanti B, Pereira G, et al. Discovery of the first potent and orally efficacious agonist of the orphan G-protein coupled receptor 119. J Med Chem. 2008;51:5172-5175.
    • (2008) J Med Chem. , vol.51 , pp. 5172-5175
    • Semple, G.1    Fioravanti, B.2    Pereira, G.3
  • 35
    • 84879092042 scopus 로고    scopus 로고
    • Discovery and optimization of potent GPR40 full agonists containing tricyclic spirocycles
    • Wang Y, Liu JJ, Dransfield PJ, et al. Discovery and optimization of potent GPR40 full agonists containing tricyclic spirocycles. ACS Med Chem Lett. 2013;4:551-555.
    • (2013) ACS Med Chem Lett. , vol.4 , pp. 551-555
    • Wang, Y.1    Liu, J.J.2    Dransfield, P.J.3
  • 37
    • 84922710254 scopus 로고    scopus 로고
    • The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium
    • Sommer F, Bäckhed F. The gut microbiota engages different signaling pathways to induce Duox2 expression in the ileum and colon epithelium. Mucosal Immunol. 2015;8:372-379.
    • (2015) Mucosal Immunol. , vol.8 , pp. 372-379
    • Sommer, F.1    Bäckhed, F.2
  • 38
    • 84923917065 scopus 로고    scopus 로고
    • An analysis of cosecretion and coexpression of gut hormones from male rat proximal and distal small intestine
    • Svendsen B, Pedersen J, Albrechtsen NJ, et al. An analysis of cosecretion and coexpression of gut hormones from male rat proximal and distal small intestine. Endocrinology. 2015;156:847-857.
    • (2015) Endocrinology , vol.156 , pp. 847-857
    • Svendsen, B.1    Pedersen, J.2    Albrechtsen, N.J.3
  • 40
    • 84884693129 scopus 로고    scopus 로고
    • GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes
    • Nøhr MK, Pedersen MH, Gille A, et al. GPR41/FFAR3 and GPR43/FFAR2 as cosensors for short-chain fatty acids in enteroendocrine cells vs FFAR3 in enteric neurons and FFAR2 in enteric leukocytes. Endocrinology. 2013;154:3552-3564.
    • (2013) Endocrinology , vol.154 , pp. 3552-3564
    • Nøhr, M.K.1    Pedersen, M.H.2    Gille, A.3
  • 41
    • 84922620529 scopus 로고    scopus 로고
    • Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes
    • Tang C, Ahmed K, Gille A, et al. Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes. Nat Med. 2015;21:173-177.
    • (2015) Nat Med. , vol.21 , pp. 173-177
    • Tang, C.1    Ahmed, K.2    Gille, A.3
  • 42
    • 0022617570 scopus 로고
    • Co-existence of glicentin and peptide YY in colorectal L-cells in cat and man. An electron microscopic study
    • Böttcher G, Alumets J, Håkanson R, Sundler F. Co-existence of glicentin and peptide YY in colorectal L-cells in cat and man. An electron microscopic study. Regul Pept. 1986;13:283-291.
    • (1986) Regul Pept. , vol.13 , pp. 283-291
    • Böttcher, G.1    Alumets, J.2    Håkanson, R.3    Sundler, F.4
  • 43
    • 84904750267 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 and peptide YY are in separate storage organelles in enteroendocrine cells
    • Cho HJ, Robinson ES, Rivera LR, et al. Glucagon-like peptide 1 and peptide YY are in separate storage organelles in enteroendocrine cells. Cell Tissue Res. 2014;357:63-69.
    • (2014) Cell Tissue Res. , vol.357 , pp. 63-69
    • Cho, H.J.1    Robinson, E.S.2    Rivera, L.R.3
  • 44
    • 0027303167 scopus 로고
    • Regulation of intestinal proglucagonderived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop
    • Roberge JN, Brubaker PL. Regulation of intestinal proglucagonderived peptide secretion by glucose-dependent insulinotropic peptide in a novel enteroendocrine loop. Endocrinology. 1993;133:233-240.
    • (1993) Endocrinology , vol.133 , pp. 233-240
    • Roberge, J.N.1    Brubaker, P.L.2
  • 45
    • 67650445631 scopus 로고    scopus 로고
    • Peripheral and central administration of xenin and neurotensin suppress food intake in rodents
    • Cooke JH, Patterson M, Patel SR, et al. Peripheral and central administration of xenin and neurotensin suppress food intake in rodents. Obesity. 2009;17:1135-1143.
    • (2009) Obesity , vol.17 , pp. 1135-1143
    • Cooke, J.H.1    Patterson, M.2    Patel, S.R.3
  • 46
    • 6344293726 scopus 로고    scopus 로고
    • Comparison of the inhibitory effects of PYY (3-36) and PYY (1-36) on gastric emptying in rats
    • Chelikani PK, Haver AC, Reidelberger RD. Comparison of the inhibitory effects of PYY (3-36) and PYY (1-36) on gastric emptying in rats. Am J Physiol Regul IntegrCompPhysiol. 2004;287:R1064-R1070.
    • (2004) Am J Physiol Regul IntegrCompPhysiol. , vol.287 , pp. R1064-R1070
    • Chelikani, P.K.1    Haver, A.C.2    Reidelberger, R.D.3
  • 47
    • 77950854036 scopus 로고    scopus 로고
    • Ghrelin and PYY in the regulation of energy balance and metabolism: Lessons from mouse mutants
    • Kirchner H, Tong J, Tschöp MH, Pfluger PT. Ghrelin and PYY in the regulation of energy balance and metabolism: lessons from mouse mutants. Am J Physiol Endocrinol Metab. 2010;298:E909-E919.
    • (2010) Am J Physiol Endocrinol Metab. , vol.298 , pp. E909-E919
    • Kirchner, H.1    Tong, J.2    Tschöp, M.H.3    Pfluger, P.T.4
  • 48
    • 0023003463 scopus 로고
    • Peptide YY release by fatty acids is sufficient to inhibit gastric emptying in dogs
    • Pappas TN, Debas HT, Chang AM, Taylor IL. Peptide YY release by fatty acids is sufficient to inhibit gastric emptying in dogs. Gastroenterology. 1986;91:1386-1389.
    • (1986) Gastroenterology , vol.91 , pp. 1386-1389
    • Pappas, T.N.1    Debas, H.T.2    Chang, A.M.3    Taylor, I.L.4
  • 49
    • 0025369062 scopus 로고
    • Mapping enteroendocrine cell populations in transgenic mice reveals an unexpected degree of complexity in cellular differentiation within the gastrointestinal tract
    • Roth KA, Hertz JM, Gordon JI. Mapping enteroendocrine cell populations in transgenic mice reveals an unexpected degree of complexity in cellular differentiation within the gastrointestinal tract. J Cell Biol. 1990;110:1791-1801.
    • (1990) J Cell Biol. , vol.110 , pp. 1791-1801
    • Roth, K.A.1    Hertz, J.M.2    Gordon, J.I.3
  • 50
    • 0025718615 scopus 로고
    • Epithelial cell differentiation in normal and transgenic mouse intestinal isografts
    • Rubin DC, Roth KA, Birkenmeier EH, Gordon JI. Epithelial cell differentiation in normal and transgenic mouse intestinal isografts. J Cell Biol. 1991;113:1183-1192.
    • (1991) J Cell Biol. , vol.113 , pp. 1183-1192
    • Rubin, D.C.1    Roth, K.A.2    Birkenmeier, E.H.3    Gordon, J.I.4
  • 51
    • 79961186689 scopus 로고    scopus 로고
    • Basic helix-loophelix transcription factors and enteroendocrine cell differentiation
    • Li HJ, Ray SK, Singh NK, Johnston B, Leiter AB. Basic helix-loophelix transcription factors and enteroendocrine cell differentiation. Diabetes Obes Metab. 2011;13(suppl 1):5-12.
    • (2011) Diabetes Obes Metab. , vol.13 , pp. 5-12
    • Li, H.J.1    Ray, S.K.2    Singh, N.K.3    Johnston, B.4    Leiter, A.B.5
  • 53
    • 38949193301 scopus 로고    scopus 로고
    • Sorting mechanism of peptide hormones and biogenesis mechanism of secretory granules by secretogranin III, a cholesterol-binding protein, in endocrine cells
    • Takeuchi T, Hosaka M. Sorting mechanism of peptide hormones and biogenesis mechanism of secretory granules by secretogranin III, a cholesterol-binding protein, in endocrine cells. Curr Diabetes Rev. 2008;4:31-38.
    • (2008) Curr Diabetes Rev. , vol.4 , pp. 31-38
    • Takeuchi, T.1    Hosaka, M.2
  • 55
    • 0023484479 scopus 로고
    • Distribution of peptide YY in the gastrointestinal tract of the rat, dog, and monkey
    • Greeley GH Jr, Hill FL, Spannagel A, Thompson JC. Distribution of peptide YY in the gastrointestinal tract of the rat, dog, and monkey. Regul Pept. 1987;19:365-372.
    • (1987) Regul Pept. , vol.19 , pp. 365-372
    • Greeley, G.H.1    Hill, F.L.2    Spannagel, A.3    Thompson, J.C.4
  • 56
    • 68949177102 scopus 로고    scopus 로고
    • Gut hormones: Implications for the treatment of obesity
    • Neary MT, Batterham RL. Gut hormones: implications for the treatment of obesity. Pharmacol Ther. 2009;124:44-56.
    • (2009) Pharmacol Ther. , vol.124 , pp. 44-56
    • Neary, M.T.1    Batterham, R.L.2
  • 57
    • 84901704935 scopus 로고    scopus 로고
    • Effects of PYY3-36 and GLP-1 on energy intake, energy expenditure, and appetite in overweight men
    • Schmidt JB, Gregersen NT, Pedersen SD, et al. Effects of PYY3-36 and GLP-1 on energy intake, energy expenditure, and appetite in overweight men. Am J Physiol Endocrinol Metab. 2014;306:E1248-E1256.
    • (2014) Am J Physiol Endocrinol Metab. , vol.306 , pp. E1248-E1256
    • Schmidt, J.B.1    Gregersen, N.T.2    Pedersen, S.D.3
  • 58
    • 78049440734 scopus 로고    scopus 로고
    • Oral administration of glucagon-like peptide 1 or peptide YY 3-36 affects food intake in healthy male subjects
    • Steinert RE, Poller B, Castelli MC, Drewe J, Beglinger C. Oral administration of glucagon-like peptide 1 or peptide YY 3-36 affects food intake in healthy male subjects. Am J Clin Nutr. 2010;92:810-817.
    • (2010) Am J Clin Nutr. , vol.92 , pp. 810-817
    • Steinert, R.E.1    Poller, B.2    Castelli, M.C.3    Drewe, J.4    Beglinger, C.5
  • 59
    • 23844554610 scopus 로고    scopus 로고
    • Peripheral exendin-4 and peptide YY (3-36) synergistically reduce food intake through different mechanisms in mice
    • Talsania T, Anini Y, Siu S, Drucker DJ, Brubaker PL. Peripheral exendin-4 and peptide YY (3-36) synergistically reduce food intake through different mechanisms in mice. Endocrinology. 2005;146:3748-3756.
    • (2005) Endocrinology , vol.146 , pp. 3748-3756
    • Talsania, T.1    Anini, Y.2    Siu, S.3    Drucker, D.J.4    Brubaker, P.L.5
  • 60
    • 84920736359 scopus 로고    scopus 로고
    • GPR40 (FFAR1) - Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo
    • Hauge M, Vestmar MA, Husted AS, et al. GPR40 (FFAR1) - Combined Gs and Gq signaling in vitro is associated with robust incretin secretagogue action ex vivo and in vivo. Mol Metab. 2015;4:3-14.
    • (2015) Mol Metab. , vol.4 , pp. 3-14
    • Hauge, M.1    Vestmar, M.A.2    Husted, A.S.3
  • 61
    • 0042831206 scopus 로고    scopus 로고
    • Mechanisms of cross-talk between G-protein-coupled receptors resulting in enhanced release of intracellular Ca2+
    • Werry TD, Wilkinson GF, Willars GB. Mechanisms of cross-talk between G-protein-coupled receptors resulting in enhanced release of intracellular Ca2+. Biochem J. 2003;374:281-296.
    • (2003) Biochem J. , vol.374 , pp. 281-296
    • Werry, T.D.1    Wilkinson, G.F.2    Willars, G.B.3
  • 62
    • 84893137029 scopus 로고    scopus 로고
    • Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance
    • Schneeberger M, Gomis R, Claret M. Hypothalamic and brainstem neuronal circuits controlling homeostatic energy balance. J Endocrinol. 2014;220:T25-T46.
    • (2014) J Endocrinol. , vol.220 , pp. T25-T46
    • Schneeberger, M.1    Gomis, R.2    Claret, M.3
  • 63
    • 0024538857 scopus 로고
    • Association of neurotensin binding sites with sensory and visceromotor components of the vagus nerve
    • Kessler JP, Beaudet A. Association of neurotensin binding sites with sensory and visceromotor components of the vagus nerve. J Neurosci. 1989;9:466-472.
    • (1989) J Neurosci. , vol.9 , pp. 466-472
    • Kessler, J.P.1    Beaudet, A.2
  • 64
    • 20244369116 scopus 로고    scopus 로고
    • The role of the vagal nerve in peripheral PYY3-36-induced feeding reduction in rats
    • Koda S, Date Y, Murakami N, et al. The role of the vagal nerve in peripheral PYY3-36-induced feeding reduction in rats. Endocrinology. 2005;146:2369-2375.
    • (2005) Endocrinology , vol.146 , pp. 2369-2375
    • Koda, S.1    Date, Y.2    Murakami, N.3
  • 65
    • 34748898831 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats
    • Vahl TP, Tauchi M, Durler TS, et al. Glucagon-like peptide-1 (GLP-1) receptors expressed on nerve terminals in the portal vein mediate the effects of endogenous GLP-1 on glucose tolerance in rats. Endocrinology. 2007;148:4965-4973.
    • (2007) Endocrinology , vol.148 , pp. 4965-4973
    • Vahl, T.P.1    Tauchi, M.2    Durler, T.S.3
  • 66
    • 67449169287 scopus 로고    scopus 로고
    • Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat
    • Bucinskaite V, Tolessa T, Pedersen J, et al. Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat. Neurogastroenterol Motil. 2009;21:978-e78.
    • (2009) Neurogastroenterol Motil. , vol.21 , pp. e978-e1178
    • Bucinskaite, V.1    Tolessa, T.2    Pedersen, J.3
  • 67
    • 84873057212 scopus 로고    scopus 로고
    • Pancreatic polypeptide and peptide YY3-36 induce Ca2+ signaling in nodose ganglion neurons
    • Iwasaki Y, Kakei M, Nakabayashi H, et al. Pancreatic polypeptide and peptide YY3-36 induce Ca2+ signaling in nodose ganglion neurons. Neuropeptides. 2013;47:19-23.
    • (2013) Neuropeptides. , vol.47 , pp. 19-23
    • Iwasaki, Y.1    Kakei, M.2    Nakabayashi, H.3
  • 68
    • 0020414770 scopus 로고
    • The stability and metabolism of intravenously administered neurotensin in the rat
    • Aronin N, Carraway RE, Ferris CF, Hammer RA, Leeman SE. The stability and metabolism of intravenously administered neurotensin in the rat. Peptides. 1982;3:637-642.
    • (1982) Peptides. , vol.3 , pp. 637-642
    • Aronin, N.1    Carraway, R.E.2    Ferris, C.F.3    Hammer, R.A.4    Leeman, S.E.5
  • 69
    • 0029118049 scopus 로고
    • Degradation of glucosedependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV
    • Kieffer TJ, McIntosh CH, Pederson RA. Degradation of glucosedependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV. Endocrinology. 1995;136:3585-3596.
    • (1995) Endocrinology , vol.136 , pp. 3585-3596
    • Kieffer, T.J.1    McIntosh, C.H.2    Pederson, R.A.3
  • 70
    • 0022891164 scopus 로고
    • Effect of neurotensin and neurotensin fragments on gastric acid secretion in man
    • Holst Pedersen J, Skov Olsen P, Kirkegaard P. Effect of neurotensin and neurotensin fragments on gastric acid secretion in man. Regul Pept. 1986;15:77-86.
    • (1986) Regul Pept. , vol.15 , pp. 77-86
    • Holst Pedersen, J.1    Skov Olsen, P.2    Kirkegaard, P.3
  • 71
    • 0023605328 scopus 로고
    • Regulation of gastric acid secretion by neurotensin in man. Evidence against a hormonal role
    • Mogard MH, Maxwell V, Sytnik B, Walsh JH. Regulation of gastric acid secretion by neurotensin in man. Evidence against a hormonal role. J Clin Invest. 1987;80:1064-1067.
    • (1987) J Clin Invest. , vol.80 , pp. 1064-1067
    • Mogard, M.H.1    Maxwell, V.2    Sytnik, B.3    Walsh, J.H.4
  • 72
    • 0032576607 scopus 로고    scopus 로고
    • Widespread expression in adult rat forebrain of mRNA encoding high-affinity neurotensin receptor
    • Alexander MJ, Leeman SE. Widespread expression in adult rat forebrain of mRNA encoding high-affinity neurotensin receptor. J Comp Neurol. 1998;402:475-500.
    • (1998) J Comp Neurol. , vol.402 , pp. 475-500
    • Alexander, M.J.1    Leeman, S.E.2
  • 73
    • 0028867442 scopus 로고
    • Distribution of GLP-1 binding sites in the rat brain: Evidence that exendin-4 is a ligand of brain GLP-1 binding sites
    • Göke R, Larsen PJ, Mikkelsen JD, Sheikh SP. Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur J Neurosci. 1995;7:2294-2300.
    • (1995) Eur J Neurosci. , vol.7 , pp. 2294-2300
    • Göke, R.1    Larsen, P.J.2    Mikkelsen, J.D.3    Sheikh, S.P.4
  • 74
    • 0031020407 scopus 로고    scopus 로고
    • Distribution of the neuropeptide Y Y2 receptor mRNA in rat central nervous system
    • Gustafson EL, Smith KE, Durkin MM, et al. Distribution of the neuropeptide Y Y2 receptor mRNA in rat central nervous system. Brain Res Mol Brain Res. 1997;46:223-235.
    • (1997) Brain Res Mol Brain Res. , vol.46 , pp. 223-235
    • Gustafson, E.L.1    Smith, K.E.2    Durkin, M.M.3
  • 75
    • 0028296105 scopus 로고
    • Saturable binding of circulating peptide YY in the dorsal vagal complex of rats
    • Hernandez EJ, Whitcomb DC, Vigna SR, Taylor IL. Saturable binding of circulating peptide YY in the dorsal vagal complex of rats. Am J Physiol. 1994;266:G511-G516.
    • (1994) Am J Physiol. , vol.266 , pp. G511-G516
    • Hernandez, E.J.1    Whitcomb, D.C.2    Vigna, S.R.3    Taylor, I.L.4
  • 76
    • 0033545166 scopus 로고    scopus 로고
    • Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system
    • Merchenthaler I, Lane M, Shughrue P. Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system. J Comp Neurol. 1999;403:261-280.
    • (1999) J Comp Neurol. , vol.403 , pp. 261-280
    • Merchenthaler, I.1    Lane, M.2    Shughrue, P.3
  • 77
    • 0028822015 scopus 로고
    • Central inhibitory action of peptide YY on gastric motility in rats
    • Chen CH, Rogers RC. Central inhibitory action of peptide YY on gastric motility in rats. Am J Physiol. 1995;269:R787-R792.
    • (1995) Am J Physiol. , vol.269 , pp. R787-R792
    • Chen, C.H.1    Rogers, R.C.2
  • 78
    • 0030913172 scopus 로고    scopus 로고
    • PYY and NPY: Control of gastric motility via action on Y1 and Y2 receptors in the DVC
    • Chen CH, Stephens RL Jr, Rogers RC. PYY and NPY: control of gastric motility via action on Y1 and Y2 receptors in the DVC. Neurogastroenterol Motil. 1997;9:109-116.
    • (1997) Neurogastroenterol Motil. , vol.9 , pp. 109-116
    • Chen, C.H.1    Stephens, R.L.2    Rogers, R.C.3
  • 79
    • 70350426017 scopus 로고    scopus 로고
    • Vagally mediated effects of glucagon-like peptide 1: In vitro and in vivo gastric actions
    • Holmes GM, Browning KN, Tong M, Qualls-Creekmore E, Travagli RA. Vagally mediated effects of glucagon-like peptide 1: in vitro and in vivo gastric actions. J Physiol. 2009;587:4749-4759.
    • (2009) J Physiol. , vol.587 , pp. 4749-4759
    • Holmes, G.M.1    Browning, K.N.2    Tong, M.3    Qualls-Creekmore, E.4    Travagli, R.A.5
  • 80
    • 18144381593 scopus 로고    scopus 로고
    • The inhibitory effects of peripheral administration of peptide YY (3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagalbrainstemhypothalamic pathway
    • Abbott CR, Monteiro M, Small CJ, et al. The inhibitory effects of peripheral administration of peptide YY (3-36) and glucagon-like peptide-1 on food intake are attenuated by ablation of the vagalbrainstemhypothalamic pathway. Brain Res. 2005;1044:127-131.
    • (2005) Brain Res. , vol.1044 , pp. 127-131
    • Abbott, C.R.1    Monteiro, M.2    Small, C.J.3
  • 82
    • 33745700396 scopus 로고    scopus 로고
    • Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs
    • Nagell CF, Wettergren A, Ørskov C, Holst JJ. Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs. Scand J Gastroenterol. 2006;41:667-672.
    • (2006) Scand J Gastroenterol. , vol.41 , pp. 667-672
    • Nagell, C.F.1    Wettergren, A.2    Ørskov, C.3    Holst, J.J.4
  • 83
    • 84908029176 scopus 로고    scopus 로고
    • Role of capsaicinsensitive peripheral sensory neurons in anorexic responses to intravenous infusions of cholecystokinin, peptide YY-(3-36), and glucagonlike peptide-1 in rats
    • Reidelberger R, Haver A, Anders K, Apenteng B. Role of capsaicinsensitive peripheral sensory neurons in anorexic responses to intravenous infusions of cholecystokinin, peptide YY-(3-36), and glucagonlike peptide-1 in rats. Am J Physiol Endocrinol Metab. 2014;307:E619-E629.
    • (2014) Am J Physiol Endocrinol Metab. , vol.307 , pp. E619-E629
    • Reidelberger, R.1    Haver, A.2    Anders, K.3    Apenteng, B.4
  • 84
    • 0023226528 scopus 로고
    • Distribution of neurotensin binding sites in the caudal brainstem of the rat: A light microscopic radioautographic study
    • Kessler JP, Moyse E, Kitabgi P, Vincent JP, Beaudet A. Distribution of neurotensin binding sites in the caudal brainstem of the rat: a light microscopic radioautographic study. Neuroscience. 1987;23:189-198.
    • (1987) Neuroscience. , vol.23 , pp. 189-198
    • Kessler, J.P.1    Moyse, E.2    Kitabgi, P.3    Vincent, J.P.4    Beaudet, A.5
  • 85
    • 0028099425 scopus 로고
    • Glucagonlike peptide 1: A newly discovered gastrointestinal hormone
    • Holst JJ. Glucagonlike peptide 1: a newly discovered gastrointestinal hormone. Gastroenterology. 1994;107:1848-1855.
    • (1994) Gastroenterology , vol.107 , pp. 1848-1855
    • Holst, J.J.1
  • 86
    • 77956184011 scopus 로고    scopus 로고
    • Neurotensin is a regulator of insulin secretion in pancreaticβ-cells
    • Béraud-Dufour S, Abderrahmani A, Noel J, et al. Neurotensin is a regulator of insulin secretion in pancreaticβ-cells. Int J Biochem Cell Biol. 2010;42:1681-1688.
    • (2010) Int J Biochem Cell Biol. , vol.42 , pp. 1681-1688
    • Béraud-Dufour, S.1    Abderrahmani, A.2    Noel, J.3
  • 87
    • 0018772033 scopus 로고
    • Effect of neurotensin on insulin, glucagon, and somatostatin release from isolated pancreatic islets
    • Dolais-Kitabgi J, Kitabgi P, Brazeau P, Freychet P. Effect of neurotensin on insulin, glucagon, and somatostatin release from isolated pancreatic islets. Endocrinology. 1979;105:256-260.
    • (1979) Endocrinology , vol.105 , pp. 256-260
    • Dolais-Kitabgi, J.1    Kitabgi, P.2    Brazeau, P.3    Freychet, P.4
  • 88
    • 0023464087 scopus 로고
    • Neurotensin induces hyperplasia of the pancreas and growth of the gastric antrum in rats
    • Feurle GE, Müller B, Rix E. Neurotensin induces hyperplasia of the pancreas and growth of the gastric antrum in rats. Gut. 1987;28(suppl):19-23.
    • (1987) Gut. , vol.28 , pp. 19-23
    • Feurle, G.E.1    Müller, B.2    Rix, E.3
  • 89
    • 0024215838 scopus 로고
    • Effect of neurotensin on pancreatic and gastric secretion and growth in rats
    • Wood JG, Hoang HD, Bussjaeger LJ, Solomon TE. Effect of neurotensin on pancreatic and gastric secretion and growth in rats. Pancreas. 1988;3:332-339.
    • (1988) Pancreas. , vol.3 , pp. 332-339
    • Wood, J.G.1    Hoang, H.D.2    Bussjaeger, L.J.3    Solomon, T.E.4
  • 91
    • 0034685687 scopus 로고    scopus 로고
    • A novel neurotensin peptide analog given extracranially decreases food intake and weight in rodents
    • Boules M, Cusack B, Zhao L, Fauq A, McCormick DJ, Richelson E. A novel neurotensin peptide analog given extracranially decreases food intake and weight in rodents. Brain Res. 2000;865:35-44.
    • (2000) Brain Res. , vol.865 , pp. 35-44
    • Boules, M.1    Cusack, B.2    Zhao, L.3    Fauq, A.4    McCormick, D.J.5    Richelson, E.6
  • 92
    • 71549120350 scopus 로고    scopus 로고
    • The acute and subchronic effects of a brain-penetrating, neurotensin-1 receptor agonist on feeding, body weight and temperature
    • Feifel D, Goldenberg J, Melendez G, Shilling PD. The acute and subchronic effects of a brain-penetrating, neurotensin-1 receptor agonist on feeding, body weight and temperature. Neuropharmacology. 2010;58:195-198.
    • (2010) Neuropharmacology , vol.58 , pp. 195-198
    • Feifel, D.1    Goldenberg, J.2    Melendez, G.3    Shilling, P.D.4
  • 93
    • 84893087602 scopus 로고    scopus 로고
    • Generation of L cells in mouse and human small intestine organoids
    • Petersen N, Reimann F, Bartfeld S, et al. Generation of L cells in mouse and human small intestine organoids. Diabetes. 2014;63:410-420.
    • (2014) Diabetes. , vol.63 , pp. 410-420
    • Petersen, N.1    Reimann, F.2    Bartfeld, S.3
  • 94
    • 84920471373 scopus 로고    scopus 로고
    • Targeting development of incretin-producing cells increases insulin secretion
    • Petersen N, Reimann F, Van Es JH, et al. Targeting development of incretin-producing cells increases insulin secretion. J Clin Invest. 2015;125:379-385.
    • (2015) J Clin Invest. , vol.125 , pp. 379-385
    • Petersen, N.1    Reimann, F.2    Van Es, J.H.3


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