Targeting development of incretin-producing cells increases insulin secretion

Journal of Clinical Investigation

Volumn 125, Issue 1, 2015, Pages 379-385

  Petersen, Natalia ^a   Reimann, Frank ^b   Van Es, Johan H ^a   Van Den Berg, Bernard M ^a,c   Kroone, Chantal ^a   Pais, Ramona ^b   Jansen, Erik ^a   Clevers, Hans ^a   Gribble, Fiona M ^b   De Koning, Eelco J P ^a,c  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b INSTITUTE OF METABOLIC SCIENCE   (United Kingdom)

^c LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

DIBENZAZEPINE DERIVATIVE; GASTRIC INHIBITORY POLYPEPTIDE; GLUCAGON; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCOSE; INCRETIN; INSULIN; NEUROGENIC DIFFERENTIATION FACTOR; NEUROGENIN 3; NOTCH RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL FUNCTION; CELL MATURATION; CELL PROLIFERATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ENRICHMENT CULTURE; GLUCOSE TOLERANCE; HORMONE RELEASE; HUMAN; HUMAN CELL; IMPAIRED GLUCOSE TOLERANCE; IN VITRO STUDY; IN VIVO STUDY; INSULIN LIKE ACTIVITY; INSULIN RELEASE; INSULIN RESPONSE; INSULIN SENSITIVITY; INSULIN TOLERANCE TEST; INTESTINE CELL; INTESTINE CRYPT; KILLER CELL; L CELL LINE; LIPID DIET; MALE; METABOLISM; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; SIGNAL TRANSDUCTION; WEIGHT CHANGE; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CELL CULTURE; CYTOLOGY; ENTEROENDOCRINE CELL; GLUCOSE INTOLERANCE; ILEUM; PHYSIOLOGY; SECRETION (PROCESS);

ANIMALS; CELLS, CULTURED; DIET, HIGH-FAT; ENTEROENDOCRINE CELLS; GLUCAGON-LIKE PEPTIDE 1; GLUCOSE INTOLERANCE; HUMANS; ILEUM; INCRETINS; INSULIN; MALE; MICE, INBRED C57BL; RECEPTORS, NOTCH;

EID: 84920471373     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI75838     Document Type: Article

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